Doctorat (H/F) EN BIOLOGIE STRUCTURALE Doctorat Nous recherchons un doctorant (H/F) pour travailler sur l'identification et la caractérisation de complexes ribonucléoprotéiques impliqués dans la réplication des virus de la Dengue et du Zika. Send your Application before : 2022.07.1 Offer published on this site from 2022.06.4 to 2022.07.1 ARN
PhD student (M/F) in molecular biology for the development of depollution enzymes by directed evolution and functional screening in microfluidic systems PhD D. student (M/F) for the development of depollution enzymes by directed evolution and functional screening in microfluidic systems. The thesis work will be carried out within the "Digital RNA Biology" team (Institute of Molecular and Cellular Biology, Strasbourg). To do this, two complementary strategies will be used in parallel, in close collaboration with the team of Prof. Stéphane Vuilleumier (University of Strasbourg). Firstly, bacteria from samples taken from sites contaminated by fluorinated compounds will be individualised in water-in-oil droplets of a few picolitres containing a minimum synthetic culture medium supplemented with the fluorinated compound to be degraded and used as a carbon source. Thus, the ability of the organism in the droplet to degrade the target compound will result not only in its growth, but also in the release of fluoride. The latter will be detected by an RNA molecular probe recently developed by the team, which converts the presence of fluoride ions into fluorescence emission. Send your Application before : 2022.06.15 Offer published on this site from 2022.05.23 to 2022.06.15 ARN
Post-doctoral fellow in structural biology and biochemistry Fixed-term contract,Researcher We are looking for a motivated post-doctoral researcher to participate in a research program (36-months contract) which will be conducted between the team “Viral ribonucleoproteins, incorporation of the genome and assembly” at UPR9002 CNRS (IBMC) and the “Chromatin stability and DNA mobility” team at UMR 7104 CNRS-U 1258 Inserm (IGBMC). The research project consists in obtaining the structure of the Pr55Gag precursor of HIV-1 in association with the genomic RNA fragment containing all the signals necessary for the specific encapsidation of the genome (Psi) by cryo-EM and X-ray crystallography. We also plan to obtain the structure of the Pr55Gag-Psi complex in the presence of the cellular and viral ligands of the p6 domain of Pr55Gag by the same methods. Send your Application before : 2022.03.8 Offer published on this site from 2022.02.15 to 2022.03.8 ARN
Poste d’assistant-e ingénieur-e H/F en biologie moléculaire et microbiologie CDD Notre unité recherche un assistant-e ingénieur-e H/F en biologie moléculaire et microbiologie. La mission consistera (i) à mettre en œuvre dans le cadre de protocoles bien établis, les techniques de base de la biologie pour la préparation du matériel biologique, ainsi qu'à (ii) apporter une aide pour l'organisation interne de l'équipe (préparation de tampons, commandes, suivi des équipements du laboratoire). Send your Application before : 2022.03.7 Offer published on this site from 2022.02.15 to 2022.03.7 ARN
Post-doctoral position (M/F) in cellular biology and signalling pathways Fixed-term contract We are currently inviting applications from enthusiastic post-doctoral candidates to participate in a research project (2-years position) conducted in a mixed public/private environment between a CNRS team and the Adisseo Company. Previously, a comparative study identified a set of new genes activated during stress situations conserved between different species. The research program centers on the characterization of cell signaling pathways controlling this genetic program and participating in the mechanisms of resistance or adaptation to stress. Send your Application before : 2022.02.28 Offer published on this site from 2022.01.19 to 2022.02.28 ARN
Ingénieur(e) (H/F) d’Etude pour la Sélection d’Aptamères par Criblage Microfluidique CDD L'équipe « Biologie Digitale de l'ARN » de l'unité « Architecture et Réactivité de l'ARN » (UPR 9002 du CNRS, Institut de Biologie Moléculaire et Cellulaire) de Strasbourg, recherche un/une ingénieur(e) d'étude dans le cadre d'un projet de Recherche et Développement en collaboration avec l'entreprise Novaptech située à Bordeaux. Send your Application before : 2022.01.25 Offer published on this site from 2022.01.10 to 2022.01.25 ARN
Position Assistant Engineer FSEP (Functions Susceptible To Be Filled) BAP A (Life, Earth and Environmental Sciences) Internal mobility An AI FSEP (Fonctions Susceptibles d'Evoirs Pourvues) BAP A (Sciences du vivant, de la terre et de l'environnement) position for internal CNRS mobility is open in the "Architecture et Réactivité de l'ARN" unit at IBMC until 17 January 2022. Send your Application before : 2022.01.17 Offer published on this site from 2021.12.14 to 2022.01.17 ARN
Research Scientist M/F in cellular and molecular virology Fixed-term contract,Researcher The project will consist in studying the innate immune response during infection of human cells, mosquitoes and ticks by the Zika virus (ZIKV) and tick-borne encephalitis virus (TBEV). More specifically, the aim will be to characterize the interactome of the viral RNA replication intermediate in order to identify new factors in antiviral response. Mass spectrometry and high throughput sequencing approaches will be implemented in these infection models. Send your Application before : 2022.01.18 Offer published on this site from 2021.11.15 to 2022.01.18 ARN
Researcher position M / F in microbiology and molecular biology Fixed-term contract,Researcher The mission of the project will consist in the analysis of RNA modifications (mainly tRNA and rRNA) in different strains of Staphylococcus aureus and in different stress conditions encountered during infections. This mapping will be performed using innovative methodologies, including mass spectrometry and high-throughput sequencing. The impact of variations in the epitranscriptome on the translation process and on the decoding rules will be analyzed at global scale by means of "ribosome profiling" and in details by in vitro translation systems. Based on the obtained results, mutations in key modifying enzymes will be analyzed for their function in the physiology and pathogenicity of S. aureus. Send your Application before : 2021.11.18 Offer published on this site from 2021.11.9 to 2021.11.18 ARN
Postdoctoral researcher M/F Fixed-term contract,Researcher The project will analyse the impact of myeloperoxidase-derived oxidants during interactions between neutrophils and the pathogenic bacterium Salmonella. In particular, the project will develop cellular models (i.e. immune cells) for the study of host-pathogen interactions. Send your Application before : 2021.11.19 Offer published on this site from 2021.10.29 to 2021.11.19 ARN
Post-doctoral fellow (M/F) in molecular biology or chemobiology Fixed-term contract,Researcher The droplet microfluidic systems used by the "Digital RNA Biology" team (Institute of Molecular and Cellular Biology, Strasbourg) allow the production and manipulation (e.g., controlled melting, sorting) of water-in-oil microdroplets of a few picolitres in size and very homogeneous in size at a rate of several thousand events per second. The present project will aim to use biomolecule capture technology to coat the inner surface of the droplets with synthetic RNA motifs. This approach will also allow the identification of molecules capable of interfering with the RNA/protein interaction. Send your Application before : 2021.11.4 Offer published on this site from 2021.10.25 to 2021.11.4 ARN
Researcher position M / F in cell biology and host-pathogenic bacteria interaction Fixed-term contract,Researcher The mission of the project will consist in analyzing the function of regulatory RNAs of Staphylococcus aureus in an infectious context. In particular, the project will require the development and use of eukaryotic cells (i.e. immune cells) and mouse models for the study of host-pathogenic bacteria interactions. Different high-throughput sequencing approaches will be used to analyze RNA expression in these different infection models. Send your Application before : 2021.11.22 Offer published on this site from 2021.10.25 to 2021.11.22 ARN
UNIVERSITY OF STRASBOURG, IMCBio graduate school International PhD call 2021 PhD Send your Application before : 2021.02.26 Offer published on this site from 2020.12.17 to 2021.02.26 ARN M3i
2-year post-doctoral fellowship Employment Send your Application before : 2020.09.1 Offer published on this site from 2020.12.1 to 2020.09.1 ARN
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