Publications
1991
Hetru Charles, Li K W, Bulet Philippe, Lagueux Marie, Hoffmann Jules A
Isolation and structural characterization of an insulin-related molecule, a predominant neuropeptide from Locusta migratoria Article de journal
Dans: Eur. J. Biochem., vol. 201, no. 2, p. 495–499, 1991, ISSN: 0014-2956.
Résumé | BibTeX | Étiquettes: Animals, Chromatography, DNA, Female, Grasshoppers, High Pressure Liquid, hoffmann, Insect Hormones, Insulin, M3i, Mass Spectrometry, Neuropeptides, Proinsulin, Protein Conformation
@article{hetru_isolation_1991,
title = {Isolation and structural characterization of an insulin-related molecule, a predominant neuropeptide from Locusta migratoria},
author = {Charles Hetru and K W Li and Philippe Bulet and Marie Lagueux and Jules A Hoffmann},
issn = {0014-2956},
year = {1991},
date = {1991-10-01},
journal = {Eur. J. Biochem.},
volume = {201},
number = {2},
pages = {495--499},
abstract = {Neurohaemal lobes of corpora cardiaca of Locusta migratoria are an established storage site for neurohormones produced by the neurosecretory cells of the brain. As previously reported [Hietter, H., Van Dorsselaer, A., Green, B., Denoroy, L., Hoffmann, J.A. & Luu, B. (1990) Eur. J. Biochem. 187, 241-247], the isolation and characterization of a novel 5-kDa peptide from these lobes served as the basis for oligonucleotide screening of cDNA libraries prepared from poly(A) RNA from neurosecretory cells of the central nervous system. From subsequent cDNA cloning studies [Lagueux, M., Lwoff, L., Meister, M., Goltzené, F. & Hoffmann, J.A. (1990) Eur. J. Biochem. 187, 249-254], the existence of a 145-residue precursor protein was deduced, which contained, in addition to the 5-kDa peptide, amino-acid sequences with homology to the A and B chains of an insulin-related peptide. In the present study we have isolated the native molecule from corpora cardiaca of Locusta and characterized, by Edman degradation and plasma-desorption mass spectrometry, the two chains as follows: A chain, Gly-Val-Phe-Asp-Glu-Cys-Cys-Arg-Lys-Ser-Cys-Ser-Ile-Ser-Glu-Leu-Gln-Thr- Tyr-Cys - Gly (Ile, isoleucine); B chain, Ser-Gly-Ala-Pro-Gln-Pro-Val-Ala-Arg-Tyr-Cys-Gly-Glu-Lys-Leu-Ser-Asn-Ala- Leu-Lys - Leu-Val-Cys-Arg-Gly-Asn-Tyr-Asn-Thr-Met-Phe. Taken in conjunction with the previous cloning studies, our data lead to a clear picture of the processing of Locusta preproinsulin. They indicate that locusta corpora cardiaca contain remarkably large amounts of one single insulin form, in contrast to multiple insulin isoforms of Bombyx mori, the only other insect species from which insulin-related peptides have been isolated and characterized [Nagasawa, H., Kataoka, H., Isogai, A., Tamura, S., Suzuki, A., Mizoguchi, A., Fujiwara, Y., Suzuki, A., Takahashi, S. & Ishizaki, H. (1986) Proc. Natl Acad. Sci. USA 83, 5840-5843].},
keywords = {Animals, Chromatography, DNA, Female, Grasshoppers, High Pressure Liquid, hoffmann, Insect Hormones, Insulin, M3i, Mass Spectrometry, Neuropeptides, Proinsulin, Protein Conformation},
pubstate = {published},
tppubtype = {article}
}
1990
Lagueux Marie, Lwoff L, Meister Marie, Goltzené F, Hoffmann Jules A
cDNAs from neurosecretory cells of brains of Locusta migratoria (Insecta, Orthoptera) encoding a novel member of the superfamily of insulins Article de journal
Dans: Eur. J. Biochem., vol. 187, no. 1, p. 249–254, 1990, ISSN: 0014-2956.
Résumé | BibTeX | Étiquettes: Animals, Base Sequence, DNA, Genes, Grasshoppers, hoffmann, Humans, Insulin, M3i, Multigene Family, Nervous System, Neuropeptides, Neurosecretory Systems, Nucleic Acid, Nucleic Acid Hybridization, Oligonucleotide Probes, RNA, Sequence Homology
@article{lagueux_cdnas_1990,
title = {cDNAs from neurosecretory cells of brains of Locusta migratoria (Insecta, Orthoptera) encoding a novel member of the superfamily of insulins},
author = {Marie Lagueux and L Lwoff and Marie Meister and F Goltzené and Jules A Hoffmann},
issn = {0014-2956},
year = {1990},
date = {1990-01-01},
journal = {Eur. J. Biochem.},
volume = {187},
number = {1},
pages = {249--254},
abstract = {From neurohaemal lobes of corpora cardiaca of Locusta migratoria a 5-kDa peptide has been isolated and its sequence established [see the accompanying paper, by Hietter et al. (1990) Eur. J. Biochem. 187, 241-247]. We have designed oligonucleotide probes from the peptide sequence of this molecule and screened a library prepared from mRNA of the neurosecretory cell region of the brain of this insect. Several positive cDNAs were isolated, the combined nucleotide sequences of which predict a large precursor of 145 residues (15770 Da) containing the newly isolated 5-kDa peptide. The peptide is flanked by regions homologous to the A and B chains of the superfamily of insulins. The overall organization of the precursor is as follows: signal peptide/domain homologous to the B chain of insulins/C (connecting)-peptide (corresponding to the newly isolated 5-kDa peptide)/domain homologous to the A chain of insulins. The numbers and relative positions of the cysteines of the Locusta peptide are equivalent to those of the other members of the insulin superfamily and most of the hydrophobic core residues are conserved.},
keywords = {Animals, Base Sequence, DNA, Genes, Grasshoppers, hoffmann, Humans, Insulin, M3i, Multigene Family, Nervous System, Neuropeptides, Neurosecretory Systems, Nucleic Acid, Nucleic Acid Hybridization, Oligonucleotide Probes, RNA, Sequence Homology},
pubstate = {published},
tppubtype = {article}
}
1989
Rosenthal G A, Reichhart Jean-Marc, Hoffmann Jules A
L-canavanine incorporation into vitellogenin and macromolecular conformation Article de journal
Dans: J. Biol. Chem., vol. 264, no. 23, p. 13693–13696, 1989, ISSN: 0021-9258.
Résumé | BibTeX | Étiquettes: Animals, Antibodies, Canavanine, fluorescence, Grasshoppers, hoffmann, M3i, Monoclonal, Protein Conformation, reichhart, Spectrometry, Vitellogenins
@article{rosenthal_l-canavanine_1989,
title = {L-canavanine incorporation into vitellogenin and macromolecular conformation},
author = {G A Rosenthal and Jean-Marc Reichhart and Jules A Hoffmann},
issn = {0021-9258},
year = {1989},
date = {1989-01-01},
journal = {J. Biol. Chem.},
volume = {264},
number = {23},
pages = {13693--13696},
abstract = {L-Canavanine is a potentially deleterious arginine antimetabolite whose toxicity is expressed in canavanine-sensitive organisms ranging from viruses to humans. Canavanine, a substrate for arginyl-tRNA synthetase, is incorporated into nascent polypeptide chains in place of arginine. This substitution results in the production of structurally aberrant, canavanyl proteins. Chemical, physical, and immunological studies of native and canavanine-containing vitellogenin obtained from female migratory locusts (Locusta migratoria migratorioides (Orthoptera] provide the first experimental evidence that canavanine can disrupt the tertiary and/or quaternary structure that yields the three-dimensional conformation unique to the protein. These findings enhance our understanding of the biochemical basis for canavanine's antimetabolic and potent insecticidal properties.},
keywords = {Animals, Antibodies, Canavanine, fluorescence, Grasshoppers, hoffmann, M3i, Monoclonal, Protein Conformation, reichhart, Spectrometry, Vitellogenins},
pubstate = {published},
tppubtype = {article}
}
1988
Kappler Christine, Kabbouh M, Hetru Charles, Durst F, Hoffmann Jules A
Characterization of three hydroxylases involved in the final steps of biosynthesis of the steroid hormone ecdysone in Locusta migratoria (Insecta, Orthoptera) Article de journal
Dans: J. Steroid Biochem., vol. 31, no. 6, p. 891–898, 1988, ISSN: 0022-4731.
Résumé | BibTeX | Étiquettes: Animals, Biological, Ecdysone, Grasshoppers, hoffmann, Kinetics, M3i, Mixed Function Oxygenases, Models, NAD, NADP, Subcellular Fractions
@article{kappler_characterization_1988,
title = {Characterization of three hydroxylases involved in the final steps of biosynthesis of the steroid hormone ecdysone in Locusta migratoria (Insecta, Orthoptera)},
author = {Christine Kappler and M Kabbouh and Charles Hetru and F Durst and Jules A Hoffmann},
issn = {0022-4731},
year = {1988},
date = {1988-12-01},
journal = {J. Steroid Biochem.},
volume = {31},
number = {6},
pages = {891--898},
abstract = {It is most generally accepted that the last three enzymatic reactions in the biosynthetic pathway of ecdysone are, in this order, the hydroxylations at positions C-25, C-22 and C-2. Using high specific activity tritiated ecdysone precursors (2,22,25-trideoxyecdysone, 2,22-dideoxyecdysone and 2-deoxyecdysone) we have characterized the hydroxylases involved in these reactions, in the major biosynthetic tissue of ecdysone, i.e. the prothoracic glands. We show that C-2 hydroxylase is a mitochondrial oxygenase which differs from conventional cytochrome P-450-dependent monooxygenases by its relative insensitivity to CO. In contrast, C-22 and C-25 hydroxylases appear as classical cytochrome P-450 monooxygenases; C-22 hydroxylase is a mitochondrial enzyme whereas our data point to a microsomal localization of the C-25 hydroxylase.},
keywords = {Animals, Biological, Ecdysone, Grasshoppers, hoffmann, Kinetics, M3i, Mixed Function Oxygenases, Models, NAD, NADP, Subcellular Fractions},
pubstate = {published},
tppubtype = {article}
}
Lanot R, Thiebold J, Costet-Corio M F, Benveniste P, Hoffmann Jules A
Further experimental evidence for the involvement of ecdysone in the control of meiotic reinitiation in oocytes of Locusta migratoria (Insecta, Orthoptera) Article de journal
Dans: Dev. Biol., vol. 126, no. 1, p. 212–214, 1988, ISSN: 0012-1606.
Résumé | BibTeX | Étiquettes: Animals, Ecdysone, Female, Grasshoppers, hoffmann, M3i, Meiosis, Oocytes, Ovary
@article{lanot_further_1988,
title = {Further experimental evidence for the involvement of ecdysone in the control of meiotic reinitiation in oocytes of Locusta migratoria (Insecta, Orthoptera)},
author = {R Lanot and J Thiebold and M F Costet-Corio and P Benveniste and Jules A Hoffmann},
issn = {0012-1606},
year = {1988},
date = {1988-03-01},
journal = {Dev. Biol.},
volume = {126},
number = {1},
pages = {212--214},
abstract = {Ecdysone has recently been shown to be able to trigger meiotic reinitiation in vitro in submature oocytes of Locusta. In the present study we have experimentally depressed (by 60-70%) ecdysone biosynthesis in the ovaries of adult females by rearing them on a diet with a modified sterol profile. Mature oocytes from such females fail to undergo normal reinitiation, but when incubated in vitro, can be induced to break their meiotic arrest by the addition of exogenous ecdysone. These results lend further support to the hypothesis that in Locusta, ovarian ecdysone is involved in the control of meiotic reinitiation.},
keywords = {Animals, Ecdysone, Female, Grasshoppers, hoffmann, M3i, Meiosis, Oocytes, Ovary},
pubstate = {published},
tppubtype = {article}
}
1985
Meister Marie F, Dimarcq Jean-Luc, Kappler Christine, Hetru Charles, Lagueux Marie, Lanot R, Luu B, Hoffmann Jules A
Conversion of a radiolabelled ecdysone precursor, 2,22,25-trideoxyecdysone, by embryonic and larval tissues of Locusta migratoria Article de journal
Dans: Mol. Cell. Endocrinol., vol. 41, no. 1, p. 27–44, 1985, ISSN: 0303-7207.
Résumé | BibTeX | Étiquettes: Abdomen, Animals, Cholestenones, Chromatography, Ecdysone, Epidermis, Fat Body, Grasshoppers, Head, High Pressure Liquid, hoffmann, Hydroxylation, Larva, M3i, Malpighian Tubules, Thorax
@article{meister_conversion_1985,
title = {Conversion of a radiolabelled ecdysone precursor, 2,22,25-trideoxyecdysone, by embryonic and larval tissues of Locusta migratoria},
author = {Marie F Meister and Jean-Luc Dimarcq and Christine Kappler and Charles Hetru and Marie Lagueux and R Lanot and B Luu and Jules A Hoffmann},
issn = {0303-7207},
year = {1985},
date = {1985-06-01},
journal = {Mol. Cell. Endocrinol.},
volume = {41},
number = {1},
pages = {27--44},
abstract = {A high specific activity tritiated ecdysone precursor, 2,22,25-trideoxyecdysone, was used to probe the capacity of various embryonic and larval tissues to perform the last 3 hydroxylation steps in ecdysone biosynthesis. Embryos at early stages of development, prior to the differentiation of their endocrine glands and embryonic heads, thoraces and abdomens of later stages, were found to have the capacity to hydroxylate the precursor to ecdysone. Larval epidermis and fat body are also able to transform 2,22,25-trideoxyecdysone into ecdysone; Malpighian tubules and midgut hydroxylate the precursor at C-2 but are apparently unable to hydroxylate both at C-22 and C-25. Larval prothoracic glands convert the precursor to ecdysone at a very efficient rate, which is 1-2 magnitudes higher than that of the other tissues investigated; several data argue for the existence of a privileged sequence of hydroxylations, C-25, C-22, C-2, in the larval prothoracic glands.},
keywords = {Abdomen, Animals, Cholestenones, Chromatography, Ecdysone, Epidermis, Fat Body, Grasshoppers, Head, High Pressure Liquid, hoffmann, Hydroxylation, Larva, M3i, Malpighian Tubules, Thorax},
pubstate = {published},
tppubtype = {article}
}
1982
Tsoupras G, Luu B, Hoffmann Jules A
Isolation and identification of three ecdysteroid conjugates with a C-20 hydroxy group in eggs of Locusta migratoria Article de journal
Dans: Steroids, vol. 40, no. 5, p. 551–560, 1982, ISSN: 0039-128X.
Résumé | BibTeX | Étiquettes: Animals, Chromatography, Ecdysone, Ecdysterone, Female, Grasshoppers, High Pressure Liquid, hoffmann, M3i, Magnetic Resonance Spectroscopy, Ovum, Phosphates, Spectrophotometry, Ultraviolet
@article{tsoupras_isolation_1982,
title = {Isolation and identification of three ecdysteroid conjugates with a C-20 hydroxy group in eggs of Locusta migratoria},
author = {G Tsoupras and B Luu and Jules A Hoffmann},
issn = {0039-128X},
year = {1982},
date = {1982-11-01},
journal = {Steroids},
volume = {40},
number = {5},
pages = {551--560},
abstract = {Three ecdysteroids conjugates with a hydroxy group at C-20 were isolated from developing eggs of locusta migratoria and identified as 22-phosphate conjugates of 2-deoxy-20-hydroxy-ecdysone, 20-hydroxyecdysone and 20-hydroxyecdysone acetate.},
keywords = {Animals, Chromatography, Ecdysone, Ecdysterone, Female, Grasshoppers, High Pressure Liquid, hoffmann, M3i, Magnetic Resonance Spectroscopy, Ovum, Phosphates, Spectrophotometry, Ultraviolet},
pubstate = {published},
tppubtype = {article}
}
1981
Lagueux Marie, Harry P, Hoffmann Jules A
Ecdysteroids are bound to vitellin in newly laid eggs of Locusta Article de journal
Dans: Mol. Cell. Endocrinol., vol. 24, no. 3, p. 325–338, 1981, ISSN: 0303-7207.
Résumé | BibTeX | Étiquettes: Animals, Chromatography, Ecdysteroids, Female, Grasshoppers, High Pressure Liquid, hoffmann, Invertebrate Hormones, Lipoproteins, M3i, Molecular Weight, Ovum, Peptide Hydrolases, Radioimmunoassay, Vitellogenins
@article{lagueux_ecdysteroids_1981,
title = {Ecdysteroids are bound to vitellin in newly laid eggs of Locusta},
author = {Marie Lagueux and P Harry and Jules A Hoffmann},
issn = {0303-7207},
year = {1981},
date = {1981-12-01},
journal = {Mol. Cell. Endocrinol.},
volume = {24},
number = {3},
pages = {325--338},
abstract = {The follicle cells of vitellogenic ovaries of Locusta migratoria have been reported to synthesize impressive amounts of ecdysteroids which accumulate inside the oöcytes where they persist during egg-laying; these ecdysteroids are conjugated to more than 95%, and it is believed that their hydrolysis in the egg is the source of the peaks of free ecdysone observed in early embryonic development. The present paper shows that, in the eggs, the ecdysteroid conjugates are bound to a 520 000-dalton macromolecule which shares several characteristics with the major yolk protein vitellin and is precipitated by an anti-vitellin antibody. The physiological relevance of the binding of ovarian ecdysteroid conjugates is discussed in respect to the transfer of maternal ecdysteroids to the embryo.},
keywords = {Animals, Chromatography, Ecdysteroids, Female, Grasshoppers, High Pressure Liquid, hoffmann, Invertebrate Hormones, Lipoproteins, M3i, Molecular Weight, Ovum, Peptide Hydrolases, Radioimmunoassay, Vitellogenins},
pubstate = {published},
tppubtype = {article}
}
1978
Goltzené F, Lagueux Marie, Charlet Maurice, Hoffmann Jules A
The follicle cell epithelium of maturing ovaries of Locusta migratoria: a new biosynthetic tissue for ecdysone Article de journal
Dans: Hoppe-Seyler's Z. Physiol. Chem., vol. 359, no. 10, p. 1427–1434, 1978, ISSN: 0018-4888.
Résumé | BibTeX | Étiquettes: Animals, Ecdysone, Epithelium, Female, Grasshoppers, hoffmann, Kinetics, M3i, Oocytes, Ovarian Follicle, Ovary, Sexual Maturation
@article{goltzene_follicle_1978,
title = {The follicle cell epithelium of maturing ovaries of Locusta migratoria: a new biosynthetic tissue for ecdysone},
author = {F Goltzené and Marie Lagueux and Maurice Charlet and Jules A Hoffmann},
issn = {0018-4888},
year = {1978},
date = {1978-10-01},
journal = {Hoppe-Seyler's Z. Physiol. Chem.},
volume = {359},
number = {10},
pages = {1427--1434},
abstract = {Follicle cells of maturing ovaries of Locusta migratoria are demonstrated to synthesize the moulting hormone ecdysone (2beta,3beta,14alpha,22R,25-pentahydroxy-5beta-cholest-7-en-6-one). Studies of secretory kinetics under in vitro conditions show that the intensity of hormone secretion is strictly dependent on the stage of maturation of the excised ovaries.},
keywords = {Animals, Ecdysone, Epithelium, Female, Grasshoppers, hoffmann, Kinetics, M3i, Oocytes, Ovarian Follicle, Ovary, Sexual Maturation},
pubstate = {published},
tppubtype = {article}
}
Hetru Charles, Lagueux Marie, Bang L, Hoffmann Jules A
Adult ovaries of Locusta migratoria contain the sequence of biosynthetic intermediates for ecdysone Article de journal
Dans: Life Sci., vol. 22, no. 23, p. 2141–2154, 1978, ISSN: 0024-3205.
BibTeX | Étiquettes: Animals, Chemical Phenomena, Chemistry, Cholesterol, Ecdysone, Female, Grasshoppers, hoffmann, M3i, Mass Spectrometry, Ovary, Ovum
@article{hetru_adult_1978,
title = {Adult ovaries of Locusta migratoria contain the sequence of biosynthetic intermediates for ecdysone},
author = {Charles Hetru and Marie Lagueux and L Bang and Jules A Hoffmann},
issn = {0024-3205},
year = {1978},
date = {1978-06-01},
journal = {Life Sci.},
volume = {22},
number = {23},
pages = {2141--2154},
keywords = {Animals, Chemical Phenomena, Chemistry, Cholesterol, Ecdysone, Female, Grasshoppers, hoffmann, M3i, Mass Spectrometry, Ovary, Ovum},
pubstate = {published},
tppubtype = {article}
}
1977
Brehelin M, Zachary Daniel, Hoffmann Jules A
Comparative study of hemocyte capsule formation in Locusta migratoria, Melolontha melolontha and Calliphora erythrocephala Article de journal
Dans: Ann Parasitol Hum Comp, vol. 52, no. 1, p. 66–67, 1977, ISSN: 0003-4150.
BibTeX | Étiquettes: Animals, Beetles, Blood Cells, Cellular, Diptera, Grasshoppers, Hemocytes, hoffmann, Immunity, M3i
@article{brehelin_comparative_1977,
title = {Comparative study of hemocyte capsule formation in Locusta migratoria, Melolontha melolontha and Calliphora erythrocephala},
author = {M Brehelin and Daniel Zachary and Jules A Hoffmann},
issn = {0003-4150},
year = {1977},
date = {1977-02-01},
journal = {Ann Parasitol Hum Comp},
volume = {52},
number = {1},
pages = {66--67},
keywords = {Animals, Beetles, Blood Cells, Cellular, Diptera, Grasshoppers, Hemocytes, hoffmann, Immunity, M3i},
pubstate = {published},
tppubtype = {article}
}
Hoffmann Danièle, Brehelin M, Hoffmann Jules A
First results of the antibacterial defense reactions of Locusta migratoria larva and imago Article de journal
Dans: Ann Parasitol Hum Comp, vol. 52, no. 1, p. 87–88, 1977, ISSN: 0003-4150.
BibTeX | Étiquettes: Animals, Bacillus thuringiensis, bacteria, Cellular, Grasshoppers, Hematopoietic System, Hemocytes, Hemolymph, hoffmann, Immunity, Larva, M3i, Muramidase
@article{hoffmann_first_1977,
title = {First results of the antibacterial defense reactions of Locusta migratoria larva and imago},
author = {Danièle Hoffmann and M Brehelin and Jules A Hoffmann},
issn = {0003-4150},
year = {1977},
date = {1977-02-01},
journal = {Ann Parasitol Hum Comp},
volume = {52},
number = {1},
pages = {87--88},
keywords = {Animals, Bacillus thuringiensis, bacteria, Cellular, Grasshoppers, Hematopoietic System, Hemocytes, Hemolymph, hoffmann, Immunity, Larva, M3i, Muramidase},
pubstate = {published},
tppubtype = {article}
}
Lagueux Marie, Hirn M, Hoffmann Jules A
Ecdysone during ovarian development in Locusta migratoria Article de journal
Dans: J. Insect Physiol., vol. 23, no. 1, p. 109–119, 1977, ISSN: 0022-1910.
BibTeX | Étiquettes: Animals, Ecdysone, Female, Grasshoppers, hoffmann, M3i, Male, Oogenesis, Ovary
@article{lagueux_ecdysone_1977,
title = {Ecdysone during ovarian development in Locusta migratoria},
author = {Marie Lagueux and M Hirn and Jules A Hoffmann},
issn = {0022-1910},
year = {1977},
date = {1977-01-01},
journal = {J. Insect Physiol.},
volume = {23},
number = {1},
pages = {109--119},
keywords = {Animals, Ecdysone, Female, Grasshoppers, hoffmann, M3i, Male, Oogenesis, Ovary},
pubstate = {published},
tppubtype = {article}
}
1976
Bang L, Lagueux Marie, Hirn M, Hoffmann Jules A
Identification, by gas chromatography and mass spectrometry, of ecdysone synthesized in the ovaries of adult female Locusta migratoria (Insecta, Orthoptera) Article de journal
Dans: C.R. Hebd. Seances Acad. Sci., Ser. D, Sci. Nat., vol. 283, no. 9, p. 1081–1084, 1976.
Résumé | BibTeX | Étiquettes: Age Factors, Animals, Chromatography, Ecdysone, Female, Gas, Grasshoppers, hoffmann, M3i, Mass Spectrometry, Ovary
@article{bang_identification_1976,
title = {Identification, by gas chromatography and mass spectrometry, of ecdysone synthesized in the ovaries of adult female Locusta migratoria (Insecta, Orthoptera)},
author = {L Bang and Marie Lagueux and M Hirn and Jules A Hoffmann},
year = {1976},
date = {1976-10-01},
journal = {C.R. Hebd. Seances Acad. Sci., Ser. D, Sci. Nat.},
volume = {283},
number = {9},
pages = {1081--1084},
abstract = {Gas chromatographic analysis, coupled to mass spectrometry, demonstrates that the considerable amounts of ecdysteroids produced in the ovaries of female adults of Locusta migratoria at the end of each ovarian cycle, consist predominantly of ecdysone.},
keywords = {Age Factors, Animals, Chromatography, Ecdysone, Female, Gas, Grasshoppers, hoffmann, M3i, Mass Spectrometry, Ovary},
pubstate = {published},
tppubtype = {article}
}
Feyereisen R, Lagueux Marie, Hoffmann Jules A
Dynamics of ecdysone metabolism after ingestion and injection in Locusta migratoria Article de journal
Dans: Gen. Comp. Endocrinol., vol. 29, no. 3, p. 319–327, 1976, ISSN: 0016-6480.
BibTeX | Étiquettes: Animals, Ecdysone, Grasshoppers, hoffmann, Hydroxylation, Injections, Intestines, Larva, M3i, Malpighian Tubules, Oral
@article{feyereisen_dynamics_1976,
title = {Dynamics of ecdysone metabolism after ingestion and injection in Locusta migratoria},
author = {R Feyereisen and Marie Lagueux and Jules A Hoffmann},
issn = {0016-6480},
year = {1976},
date = {1976-07-01},
journal = {Gen. Comp. Endocrinol.},
volume = {29},
number = {3},
pages = {319--327},
keywords = {Animals, Ecdysone, Grasshoppers, hoffmann, Hydroxylation, Injections, Intestines, Larva, M3i, Malpighian Tubules, Oral},
pubstate = {published},
tppubtype = {article}
}
Lagueux Marie, Hirn M, de Reggi M, Hoffmann Jules A
Ecdysteroid levels and ovarian development in adult female Locust migratoria Article de journal
Dans: C.R. Hebd. Seances Acad. Sci., Ser. D, Sci. Nat., vol. 282, no. 12, p. 1187–1190, 1976.
Résumé | BibTeX | Étiquettes: Adipose Tissue, Animals, Castration, Female, Grasshoppers, Hemolymph, hoffmann, Invertebrate Hormones, M3i, Neurosecretory Systems, Oogenesis, Ovary, Oviposition
@article{lagueux_ecdysteroid_1976,
title = {Ecdysteroid levels and ovarian development in adult female Locust migratoria},
author = {Marie Lagueux and M Hirn and M de Reggi and Jules A Hoffmann},
year = {1976},
date = {1976-03-01},
journal = {C.R. Hebd. Seances Acad. Sci., Ser. D, Sci. Nat.},
volume = {282},
number = {12},
pages = {1187--1190},
abstract = {During ovarian development in adult females of Locusta, an important biosynthesis of ecdysteroids is observed at the end of the maturation process of the terminal oocyte. This phenomenon occurs regularly during the different ovarian cycles. No synthesis is observed in allatectomized or ovariectomized female adults.},
keywords = {Adipose Tissue, Animals, Castration, Female, Grasshoppers, Hemolymph, hoffmann, Invertebrate Hormones, M3i, Neurosecretory Systems, Oogenesis, Ovary, Oviposition},
pubstate = {published},
tppubtype = {article}
}
1975
Feyereisen R, Lagueux Marie, Hoffmann Jules A
The hemolymphatic transport of molting hormone during the development of Locusta migratoria L Article de journal
Dans: C.R. Hebd. Seances Acad. Sci., Ser. D, Sci. Nat., vol. 280, no. 14, p. 1709–1712, 1975.
Résumé | BibTeX | Étiquettes: Age Factors, Animals, Carrier Proteins, Chromatography, Ecdysone, Ecdysterone, Gel, Grasshoppers, Hematopoietic System, hoffmann, Larva, M3i, Neurosecretory Systems, Protein Binding, Time Factors
@article{feyereisen_hemolymphatic_1975,
title = {The hemolymphatic transport of molting hormone during the development of Locusta migratoria L},
author = {R Feyereisen and Marie Lagueux and Jules A Hoffmann},
year = {1975},
date = {1975-04-01},
journal = {C.R. Hebd. Seances Acad. Sci., Ser. D, Sci. Nat.},
volume = {280},
number = {14},
pages = {1709--1712},
abstract = {Shortly after injection of radio-labelled ecdysone into fifth instar larvae of Locusta migratoria, 20-hydroxy-ecdysone (ecdysterone) is the main hormone found in the blood. Some 10% of the circulating hormone are bound to hemolymph macromolecules. The ratio of bound to free hormone is stage-dependent; it decreases considerably after previous injections of non-labelled ecdysone, but increases in insects in which ecdysone biosynthesis has been blocked by extirpation of the prothoracic glands or selective X-ray treatment of the hemocytopoietic tissue.},
keywords = {Age Factors, Animals, Carrier Proteins, Chromatography, Ecdysone, Ecdysterone, Gel, Grasshoppers, Hematopoietic System, hoffmann, Larva, M3i, Neurosecretory Systems, Protein Binding, Time Factors},
pubstate = {published},
tppubtype = {article}
}
Hoffmann Jules A, Koolman J, Beyler C
The role of the prothoracic glands in the production of ecdysone during the last larval instar of Locusta migratoria L Article de journal
Dans: C.R. Hebd. Seances Acad. Sci., Ser. D, Sci. Nat., vol. 280, no. 6, p. 733–736, 1975.
Résumé | BibTeX | Étiquettes: Animals, Cholesterol, Ecdysone, Grasshoppers, hoffmann, Larva, M3i
@article{hoffmann_role_1975,
title = {The role of the prothoracic glands in the production of ecdysone during the last larval instar of Locusta migratoria L},
author = {Jules A Hoffmann and J Koolman and C Beyler},
year = {1975},
date = {1975-02-01},
journal = {C.R. Hebd. Seances Acad. Sci., Ser. D, Sci. Nat.},
volume = {280},
number = {6},
pages = {733--736},
abstract = {Tritiated cholesterol is rapidly converted to labelled ecdysone in vitro by prothoracic glands from last instar larvae of Locusta at the time of the maximum endogenous hormone increase of the insects. Glands from larvae with low hormone content or fat body fragments do not make similar conversions.},
keywords = {Animals, Cholesterol, Ecdysone, Grasshoppers, hoffmann, Larva, M3i},
pubstate = {published},
tppubtype = {article}
}
1974
Hoffmann Danièle, Brehelin M, Hoffmann Jules A
Modifications of the hemogram and of the hemocytopoietic tissue of male adults of Locusta migratoria (Orthoptera) after injection of Bacillus thuringiensis Article de journal
Dans: J. Invertebr. Pathol., vol. 24, no. 2, p. 238–247, 1974, ISSN: 0022-2011.
BibTeX | Étiquettes: Bacillus, Blood Cell Count, Grasshoppers, Hematopoietic System, hoffmann, M3i
@article{hoffmann_modifications_1974,
title = {Modifications of the hemogram and of the hemocytopoietic tissue of male adults of Locusta migratoria (Orthoptera) after injection of Bacillus thuringiensis},
author = {Danièle Hoffmann and M Brehelin and Jules A Hoffmann},
issn = {0022-2011},
year = {1974},
date = {1974-09-01},
journal = {J. Invertebr. Pathol.},
volume = {24},
number = {2},
pages = {238--247},
keywords = {Bacillus, Blood Cell Count, Grasshoppers, Hematopoietic System, hoffmann, M3i},
pubstate = {published},
tppubtype = {article}
}
Hoffmann Jules A, Koolman J
Prothoracic glands in the regulation of ecdysone titres and metabolic fate of injected labelled ecdysone in Locusta migratoria Article de journal
Dans: J. Insect Physiol., vol. 20, no. 8, p. 1593–1601, 1974, ISSN: 0022-1910.
BibTeX | Étiquettes: Animals, Ecdysone, Grasshoppers, hoffmann, Injections, M3i
@article{hoffmann_prothoracic_1974,
title = {Prothoracic glands in the regulation of ecdysone titres and metabolic fate of injected labelled ecdysone in Locusta migratoria},
author = {Jules A Hoffmann and J Koolman},
issn = {0022-1910},
year = {1974},
date = {1974-08-01},
journal = {J. Insect Physiol.},
volume = {20},
number = {8},
pages = {1593--1601},
keywords = {Animals, Ecdysone, Grasshoppers, hoffmann, Injections, M3i},
pubstate = {published},
tppubtype = {article}
}
Hoffmann Jules A, Weins M J
Active protein synthesis in the prothoracic glands and ecdysone titer in the permanent larvae of Locusta migratoria after selective irradiation of hematopoietic tissue Article de journal
Dans: Experientia, vol. 30, no. 7, p. 821–822, 1974, ISSN: 0014-4754.
BibTeX | Étiquettes: Animals, Ecdysone, Grasshoppers, Hematopoietic System, hoffmann, Larva, Leucine, M3i, Protein Biosynthesis, Radiation Effects, Tritium
@article{hoffmann_active_1974,
title = {Active protein synthesis in the prothoracic glands and ecdysone titer in the permanent larvae of Locusta migratoria after selective irradiation of hematopoietic tissue},
author = {Jules A Hoffmann and M J Weins},
issn = {0014-4754},
year = {1974},
date = {1974-07-01},
journal = {Experientia},
volume = {30},
number = {7},
pages = {821--822},
keywords = {Animals, Ecdysone, Grasshoppers, Hematopoietic System, hoffmann, Larva, Leucine, M3i, Protein Biosynthesis, Radiation Effects, Tritium},
pubstate = {published},
tppubtype = {article}
}
Goltzené F, Hoffmann Jules A
Control of haemolymph protein synthesis and oocyte maturation by the corpora allata in female adults of locusta migratoria (Orthoptera): role of the blood-forming tissue Article de journal
Dans: Gen. Comp. Endocrinol., vol. 22, no. 4, p. 489–498, 1974, ISSN: 0016-6480.
BibTeX | Étiquettes: Animals, Disc, Electrophoresis, Female, Grasshoppers, Hematopoietic System, Hemolymph, hoffmann, M3i, Ovum, Protein Biosynthesis, Radiation Effects
@article{goltzene_control_1974,
title = {Control of haemolymph protein synthesis and oocyte maturation by the corpora allata in female adults of locusta migratoria (Orthoptera): role of the blood-forming tissue},
author = {F Goltzené and Jules A Hoffmann},
issn = {0016-6480},
year = {1974},
date = {1974-04-01},
journal = {Gen. Comp. Endocrinol.},
volume = {22},
number = {4},
pages = {489--498},
keywords = {Animals, Disc, Electrophoresis, Female, Grasshoppers, Hematopoietic System, Hemolymph, hoffmann, M3i, Ovum, Protein Biosynthesis, Radiation Effects},
pubstate = {published},
tppubtype = {article}
}
Hoffmann Jules A, Koolman J, Karlson P, Joly P
Molting hormone titer and metabolic fate of injected ecdysone during the fifth larval instar and in adults of Locusta migratoria (Orthoptera) Article de journal
Dans: Gen. Comp. Endocrinol., vol. 22, no. 1, p. 90–97, 1974, ISSN: 0016-6480.
BibTeX | Étiquettes: Age Factors, Animals, Chromatography, Ecdysone, Feces, Grasshoppers, hoffmann, Hydroxylation, Invertebrate Hormones, Larva, M3i, Thin Layer, Time Factors, Tritium
@article{hoffmann_molting_1974,
title = {Molting hormone titer and metabolic fate of injected ecdysone during the fifth larval instar and in adults of Locusta migratoria (Orthoptera)},
author = {Jules A Hoffmann and J Koolman and P Karlson and P Joly},
issn = {0016-6480},
year = {1974},
date = {1974-01-01},
journal = {Gen. Comp. Endocrinol.},
volume = {22},
number = {1},
pages = {90--97},
keywords = {Age Factors, Animals, Chromatography, Ecdysone, Feces, Grasshoppers, hoffmann, Hydroxylation, Invertebrate Hormones, Larva, M3i, Thin Layer, Time Factors, Tritium},
pubstate = {published},
tppubtype = {article}
}
1973
Koolman J, Hoffmann Jules A, Karlson P
Sulphage esters as inactivation products of ecdysone in Locusta migratoria Article de journal
Dans: Hoppe-Seyler's Z. Physiol. Chem., vol. 354, no. 9, p. 1043–1048, 1973, ISSN: 0018-4888.
BibTeX | Étiquettes: Animals, Biological, Cattle, Chromatography, Ecdysone, Electrophoresis, Esterases, Glucosidases, Glucuronidase, Grasshoppers, hoffmann, Hydrogen-Ion Concentration, Hydrolysis, Ion Exchange, Isotope Labeling, Kinetics, Larva, Liver, M3i, Metamorphosis, Paper, Plants, Saccharomyces cerevisiae, Snails, Sulfatases, Sulfur Radioisotopes, Sulfuric Acids, Swine, Thin Layer, Time Factors, Tritium
@article{koolman_sulphage_1973,
title = {Sulphage esters as inactivation products of ecdysone in Locusta migratoria},
author = {J Koolman and Jules A Hoffmann and P Karlson},
issn = {0018-4888},
year = {1973},
date = {1973-09-01},
journal = {Hoppe-Seyler's Z. Physiol. Chem.},
volume = {354},
number = {9},
pages = {1043--1048},
keywords = {Animals, Biological, Cattle, Chromatography, Ecdysone, Electrophoresis, Esterases, Glucosidases, Glucuronidase, Grasshoppers, hoffmann, Hydrogen-Ion Concentration, Hydrolysis, Ion Exchange, Isotope Labeling, Kinetics, Larva, Liver, M3i, Metamorphosis, Paper, Plants, Saccharomyces cerevisiae, Snails, Sulfatases, Sulfur Radioisotopes, Sulfuric Acids, Swine, Thin Layer, Time Factors, Tritium},
pubstate = {published},
tppubtype = {article}
}
Joly L, Weins M J, Hoffmann Jules A, Porte A
Development of the prothoracic glands of permanent larvae of Locusta migratoria obtained by selective irradiation of the hemocytopoietic tissue Article de journal
Dans: Z Zellforsch Mikrosk Anat, vol. 137, no. 3, p. 387–397, 1973, ISSN: 0340-0336.
BibTeX | Étiquettes: Age Factors, Animals, Biological, Ecdysone, Electron, Endocrine Glands, Golgi Apparatus, Grasshoppers, hoffmann, Larva, M3i, Metamorphosis, Microscopy, Radiation Effects, ribosomes
@article{joly_development_1973,
title = {Development of the prothoracic glands of permanent larvae of Locusta migratoria obtained by selective irradiation of the hemocytopoietic tissue},
author = {L Joly and M J Weins and Jules A Hoffmann and A Porte},
issn = {0340-0336},
year = {1973},
date = {1973-02-01},
journal = {Z Zellforsch Mikrosk Anat},
volume = {137},
number = {3},
pages = {387--397},
keywords = {Age Factors, Animals, Biological, Ecdysone, Electron, Endocrine Glands, Golgi Apparatus, Grasshoppers, hoffmann, Larva, M3i, Metamorphosis, Microscopy, Radiation Effects, ribosomes},
pubstate = {published},
tppubtype = {article}
}