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Gottar Marie, Gobert Vanessa, Michel Tatiana, Belvin Marcia, Duyk Geoffrey, Hoffmann Jules A, Ferrandon Dominique, Royet Julien

The Drosophila immune response against Gram-negative bacteria is mediated by a peptidoglycan recognition protein Journal Article

In: Nature, vol. 416, pp. 640–644, 2002, ISBN: 0028-0836.

Abstract | Links | BibTeX | Tags: Animal, Anti-Infective Agents/metabolism, Carrier Proteins/biosynthesis/genetics/*immunology, Drosophila melanogaster/genetics/*immunology/*microbiology, Drosophila Proteins/genetics/metabolism, Epistasis, Female, ferrandon, Genes, Genetic, Genetic Predisposition to Disease, Gram-Negative Bacteria/*immunology/physiology, hoffmann, Human, Insect/genetics, M3i, Messenger/genetics/metabolism, Mutation, Non-U.S. Gov't, P.H.S., Phenotype, RNA, Signal Transduction, Support, Survival Rate, Transgenes/genetics, U.S. Gov't

Cristofari G., Bampi C., Wilhelm M., Wilhelm F. X., Darlix J. L.

A 5'-3' long-range interaction in Ty1 RNA controls its reverse transcription and retrotransposition Journal Article

In: EMBO J, vol. 21, no. 16, pp. 4368-79, 2002, (0261-4189 Journal Article).

Abstract | BibTeX | Tags: *Gene, *Transcription, Acid, cerevisiae/*genetics, Complementary/biosynthesis, Conformation, DNA, Expression, Fungal, Fungal/chemistry/*metabolism, Genetic, Gov't, in, Messenger/chemistry/*metabolism, Non-U.S., Nucleic, Phylogeny, Regulation, Retroelements/*genetics, RNA, Saccharomyces, Support, vitro

Perederina A., Nevskaya N., Nikonov O., Nikulin A., Dumas P., Yao M., Tanaka I., Garber M., Gongadze G., Nikonov S.

Detailed analysis of RNA-protein interactions within the bacterial ribosomal protein L5/5S rRNA complex Journal Article

In: RNA, vol. 8, no. 12, pp. 1548-57, 2002, (1355-8382 Journal Article).

Abstract | BibTeX | Tags: 5S/*chemistry/*metabolism, Acid, Amino, Bacterial, Base, Binding, Bonding, coli/genetics, Conformation, Data, Escherichia, Fragments/chemistry/metabolism, Gov't, Hydrogen, Models, Molecular, Non-U.S., Nucleic, Peptide, Protein, Proteins/*chemistry/*metabolism, Proteins/chemistry/metabolism, Ribosomal, RNA, Sequence, Sites, Support


Vizioli J, Bulet Philippe, Hoffmann Jules A, Kafatos Fotis C, Müller H M, Dimopoulos G

Gambicin: a novel immune responsive antimicrobial peptide from the malaria vector Anopheles gambiae Journal Article

In: Proc. Natl. Acad. Sci. U.S.A., vol. 98, no. 22, pp. 12630–12635, 2001, ISSN: 0027-8424.

Abstract | Links | BibTeX | Tags: Animals, Anopheles, Anti-Bacterial Agents, Anti-Infective Agents, Base Sequence, Chromosome Mapping, hoffmann, Insect Proteins, Insect Vectors, M3i, Malaria, messenger, RNA

Boutabout M., Wilhelm M., Wilhelm F. X.

DNA synthesis fidelity by the reverse transcriptase of the yeast retrotransposon Ty1 Journal Article

In: Nucleic Acids Res, vol. 29, no. 11, pp. 2217-22, 2001, (1362-4962 Journal Article).

Abstract | BibTeX | Tags: cerevisiae/*genetics/metabolism, DNA, Fungal/genetics, Fungal/genetics/*metabolism, Genetic, Gov't, Kinetics, Non-U.S., Nucleotides/genetics/metabolism, Polymerase/*metabolism, Retroelements/*genetics, RNA, RNA-Directed, Saccharomyces, Support, Templates

Carnicelli D., Brigotti M., Rizzi S., Keith G., Montanaro L., Sperti S.

Nucleotides U28-A42 and A37 in unmodified yeast tRNA(Trp) as negative identity elements for bovine tryptophanyl-tRNA synthetase Journal Article

In: FEBS Lett, vol. 492, no. 3, pp. 238-41, 2001, (0014-5793 Journal Article).

Abstract | BibTeX | Tags: Acid, Adenine/chemistry, Animals, Base, Cattle, cerevisiae/genetics, Conformation, Data, Fungal/genetics/metabolism, Gov't, Kinetics, Ligase/*metabolism, Molecular, Non-U.S., Nucleic, RNA, Saccharomyces, Sequence, Species, Specificity, Substrate, Support, Transfer, Trp/chemistry/*metabolism, Tryptophan-tRNA, Uridine/chemistry

Moine H., Mandel J. L.

Biomedicine. Do G quartets orchestrate fragile X pathology? Journal Article

In: Science, vol. 294, no. 5551, pp. 2487-8, 2001, (0036-8075 Journal Article).

BibTeX | Tags: Acid, Analysis, Animals, Array, Binding, Brain/metabolism, Conformation, Crystallography, Expression, Fragile, Gene, Genetic, Human, Messenger/*chemistry/genetics/*metabolism, Mice, Nerve, Nucleic, Oligonucleotide, Protein, Proteins/chemistry/genetics/*metabolism, Regions, Regulation, RNA, Sequence, Sites, structure, Synapses/physiology, Syndrome/genetics/*metabolism, Tertiary, Tissue, Translation, Untranslated, X, X-Ray

Levashina Elena A, Moita L F, Blandin Stéphanie A, Vriend G, Lagueux Marie, Kafatos F C

Conserved role of a complement-like protein in phagocytosis revealed by dsRNA knockout in cultured cells of the mosquito, Anopheles gambiae Journal Article

In: Cell, vol. 104, no. 5, pp. 709–718, 2001, ISSN: 0092-8674.

Abstract | BibTeX | Tags: alpha-Macroglobulins, Animals, Anopheles, blandin, Cells, Cloning, Complement C3, Cultured, DNA Fragmentation, Double-Stranded, Female, Genetic, Gram-Negative Bacteria, Hemocytes, Insect Proteins, M3i, Molecular, Nucleic Acid Denaturation, Phagocytosis, Protein Structure, RNA, Tertiary, Transcription


Dumortier H, Monneaux F, Jahn-Schmid B, Briand J P, Skriner K, Cohen P L, Smolen J S, Steiner G, Muller S

B and Ŧ cell responses to the spliceosomal heterogeneous nuclear ribonucleoproteins A2 and B1 in normal and lupus mice Journal Article

In: Journal of Immunology (Baltimore, Md.: 1950), vol. 165, no. 4, pp. 2297–2305, 2000, ISSN: 0022-1767.

Abstract | Links | BibTeX | Tags: Amino Acid Sequence, Animals, Autoantibodies, B-Lymphocytes, Dumortier, Epitope Mapping, Female, Heterogeneous Nuclear, Heterogeneous-Nuclear Ribonucleoprotein Group A-B, Heterogeneous-Nuclear Ribonucleoproteins, Humans, I2CT, Immunoglobulin G, Inbred BALB C, Inbred C57BL, Inbred CBA, Inbred MRL lpr, Injections, Lupus Nephritis, Lymphocyte Activation, Male, Mice, Molecular Sequence Data, Monneaux, Peptide Fragments, Recombinant Proteins, Ribonucleoproteins, RNA, Spliceosomes, Subcutaneous, T-Lymphocytes, Team-Dumortier, transgenic

Delagoutte B., Keith G., Moras D., Cavarelli J.

Crystallization and preliminary X-ray crystallographic analysis of yeast arginyl-tRNA synthetase-yeast tRNAArg complexes Journal Article

In: Acta Crystallogr D Biol Crystallogr, vol. 56, no. Pt 4, pp. 492-4, 2000, (0907-4449 Journal Article).

Abstract | BibTeX | Tags: &, Arg/*chemistry/isolation, Arginine-tRNA, cerevisiae/enzymology/genetics, Crystallization, Crystallography, Fungal/chemistry/isolation, Gov't, Ligase/*chemistry/isolation, Non-U.S., purification/*metabolism, purification/metabolism, RNA, Saccharomyces, Support, Transfer, X-Ray

Jaeger L., Leontis N. B.

Tecto-RNA: One-Dimensional Self-Assembly through Tertiary Interactions Journal Article

In: Angew Chem Int Ed Engl, vol. 39, no. 14, pp. 2521-2524, 2000.

Abstract | BibTeX | Tags: Chemistry, RNA, self-organisation, supramolecular


Auxilien S., Keith G., Grice S. F. Le, Darlix J. L.

Role of post-transcriptional modifications of primer tRNALys,3 in the fidelity and efficacy of plus strand DNA transfer during HIV-1 reverse transcription Journal Article

In: J Biol Chem, vol. 274, no. 7, pp. 4412-20, 1999, (0021-9258 Journal Article).

Abstract | BibTeX | Tags: *RNA, *Transcription, Acid, Base, Calf, Conformation, Data, DNA, Genetic, Gov't, H, HIV-1, HIV-1/*physiology, Lys/*metabolism, Molecular, Non-U.S., Nucleic, post-transcriptional, Processing, Reverse, Ribonuclease, RNA, Sequence, Support, Templates, Thymus/metabolism, Transcriptase/metabolism, Transfer, Viral/*metabolism, Viral/metabolism

Perreau V. M., Keith G., Holmes W. M., Przykorska A., Santos M. A., Tuite M. F.

The Candida albicans CUG-decoding ser-tRNA has an atypical anticodon stem-loop structure Journal Article

In: J Mol Biol, vol. 293, no. 5, pp. 1039-53, 1999, (0022-2836 Journal Article).

Abstract | BibTeX | Tags: *Nucleic, Acid, albicans/*genetics, Anticodon/*chemistry/*genetics/metabolism, Base, Candida, cerevisiae/genetics, Code/genetics, Conformation, Evolution, Fungal/chemistry/genetics/metabolism, Genetic, Gov't, Imidazoles/metabolism, Lead/metabolism, Methylation, Methyltransferases/metabolism, Molecular, Mutation/genetics, Non-P.H.S., Non-U.S., Nucleosides/genetics/metabolism, P.H.S., Ribonucleases/metabolism, RNA, Saccharomyces, Sequence, Ser/*chemistry/*genetics/metabolism, Solutions, Support, Transfer, tRNA, U.S.

Lowenberger C A, Kamal S, Chiles J, Paskewitz S, Bulet Philippe, Hoffmann Jules A, Christensen B M

Mosquito-Plasmodium interactions in response to immune activation of the vector Journal Article

In: Exp. Parasitol., vol. 91, no. 1, pp. 59–69, 1999, ISSN: 0014-4894.

Abstract | Links | BibTeX | Tags: Aedes, Animals, Anopheles, Culicidae, Defensins, Digestive System, Escherichia coli, Female, Genetic, Hemolymph, hoffmann, Insect Vectors, M3i, messenger, Micrococcus luteus, Plasmodium, Plasmodium berghei, Plasmodium gallinaceum, Proteins, Reverse Transcriptase Polymerase Chain Reaction, RNA, Transcription


Uttenweiler-Joseph S, Moniatte M, Lagueux Marie, Dorsselaer Van A, Hoffmann Jules A, Bulet Philippe

Differential display of peptides induced during the immune response of Drosophila: a matrix-assisted laser desorption ionization time-of-flight mass spectrometry study Journal Article

In: Proc. Natl. Acad. Sci. U.S.A., vol. 95, no. 19, pp. 11342–11347, 1998, ISSN: 0027-8424.

Abstract | BibTeX | Tags: Animals, bacteria, Chromatography, Cloning, Hemolymph, High Pressure Liquid, hoffmann, Immunity, Insect Proteins, M3i, Mass, Matrix-Assisted Laser Desorption-Ionization, messenger, Molecular, Peptides, Protein Precursors, RNA, Sequence Analysis, Spectrometry, Time Factors

Brigotti M., Keith G., Pallanca A., Carnicelli D., Alvergna P., Dirheimer G., Montanaro L., Sperti S.

Identification of the tRNAs which up-regulate agrostin, barley RIP and PAP-S, three ribosome-inactivating proteins of plant origin Journal Article

In: FEBS Lett, vol. 431, no. 2, pp. 259-62, 1998, (0014-5793 Journal Article).

Abstract | BibTeX | Tags: &, Acid, Adenosine, Base, Conformation, Data, effects/*metabolism, Gov't, Hordeum/metabolism, Hydrolases/*metabolism, Molecular, N-Glycosyl, Non-U.S., Nucleic, Plant, Plant/chemistry/isolation, Proteins/drug, purification/*metabolism, RNA, Sequence, Support, Transfer/chemistry/isolation, Triphosphate/pharmacology, Up-Regulation

Friant S., Heyman T., Bystrom A. S., Wilhelm M., Wilhelm F. X.

Interactions between Ty1 retrotransposon RNA and the T and D regions of the tRNA(iMet) primer are required for initiation of reverse transcription in vivo Journal Article

In: Mol Cell Biol, vol. 18, no. 2, pp. 799-806, 1998, (0270-7306 Journal Article).

Abstract | BibTeX | Tags: *Retroelements, *Transcription, Acid, Base, Binding, cerevisiae, Conformation, Data, DNA, Fungal/*metabolism, Fungal/biosynthesis, Genetic, Gov't, Met/*metabolism, Molecular, Mutagenesis, Non-U.S., Nucleic, Primers, Replication, RNA, Saccharomyces, Sequence, Sites, Support, Transfer

Gabus C., Ficheux D., Rau M., Keith G., Sandmeyer S., Darlix J. L.

The yeast Ty3 retrotransposon contains a 5'-3' bipartite primer-binding site and encodes nucleocapsid protein NCp9 functionally homologous to HIV-1 NCp7 Journal Article

In: EMBO J, vol. 17, no. 16, pp. 4873-80, 1998, (0261-4189 Journal Article).

Abstract | BibTeX | Tags: *Capsid, *Retroelements, Acid, Base, Binding, Capsid/*genetics, cerevisiae/*genetics, dimerization, gag/*genetics, Gene, Gov't, Homology, Met/genetics/*metabolism, Non-U.S., Nucleic, P.H.S., Products, Proteins, RNA, Saccharomyces, Sequence, Sites, Support, Transfer, U.S.

Motorin Y., Keith G., Simon C., Foiret D., Simos G., Hurt E., Grosjean H.

The yeast tRNA:pseudouridine synthase Pus1p displays a multisite substrate specificity Journal Article

In: RNA, vol. 4, no. 7, pp. 856-69, 1998, (1355-8382 Journal Article).

Abstract | BibTeX | Tags: *RNA, cerevisiae, Cloning, Fractions/metabolism, Fungal, Fungal/metabolism, Gov't, Hydro-Lyases/biosynthesis/genetics/*metabolism, Molecular, Mutation, Non-U.S., Plant/metabolism, post-transcriptional, Precursors/*metabolism, Processing, Proteins/biosynthesis, Proteins/biosynthesis/genetics/metabolism, Pseudouridine/*biosynthesis, Recombinant, RNA, Saccharomyces, Specificity, Subcellular, Substrate, Support, Transfer/*metabolism


Friant S., Heyman T., Poch O., Wilhelm M., Wilhelm F. X.

Sequence comparison of the Ty1 and Ty2 elements of the yeast genome supports the structural model of the tRNAiMet-Ty1 RNA reverse transcription initiation complex Journal Article

In: Yeast, vol. 13, no. 7, pp. 639-45, 1997, (0749-503x Journal Article).

Abstract | BibTeX | Tags: *Sequence, Acid, Alignment, Amino, Analysis, Base, Data, DNA, Elements/*genetics, Fungal/genetics, Gov't, Met/*chemistry/*genetics, Molecular, Non-U.S., RNA, Sequence, structure, Support, Transfer, Transposable, Yeasts/*genetics

Wilhelm M., Heyman T., Friant S., Wilhelm F. X.

Heterogeneous terminal structure of Ty1 and Ty3 reverse transcripts Journal Article

In: Nucleic Acids Res, vol. 25, no. 11, pp. 2161-6, 1997, (0305-1048 Journal Article).

Abstract | BibTeX | Tags: *Nucleic, *Transcription, Acid, Calf, Chain, Conformation, DNA, Fungal/*chemistry/metabolism, Genetic, Gov't, H, Hybridization, Non-U.S., Nucleic, Plasmids/chemistry/genetics/metabolism, Polymerase, Reaction, Replication, Retroelements/*genetics, Ribonuclease, RNA, Support, Thymus/metabolism, Transfer/chemistry


Lowenberger C A, Ferdig M T, Bulet Philippe, Khalili S, Hoffmann Jules A, Christensen B M

Aedes aegypti: induced antibacterial proteins reduce the establishment and development of Brugia malayi Journal Article

In: Exp. Parasitol., vol. 83, no. 2, pp. 191–201, 1996, ISSN: 0014-4894.

Abstract | Links | BibTeX | Tags: Aedes, Analysis of Variance, Animals, Anti-Bacterial Agents, Base Sequence, Blood Proteins, Blotting, Brugia malayi, Culicidae, Defensins, DNA, Escherichia coli, Fat Body, Genetic, Gerbillinae, hoffmann, M3i, Micrococcus luteus, Microfilaria, Northern, RNA, Transcription

Friant S., Heyman T., Wilhelm F. X., Wilhelm M.

Role of RNA primers in initiation of minus-strand and plus-strand DNA synthesis of the yeast retrotransposon Ty1 Journal Article

In: Biochimie, vol. 78, no. 7, pp. 674-80, 1996, (0300-9084 Journal Article).

Abstract | BibTeX | Tags: *DNA, Acid, Bacterial/*metabolism, Complementary/metabolism, Conformation, Data, DNA, Elements, Gov't, Molecular, Mutagenesis, Non-U.S., Nucleic, Replication, RNA, RNA/*metabolism, Sequence, Support, Transposable

Friant S., Heyman T., Wilhelm M. L., Wilhelm F. X.

Extended interactions between the primer tRNAi(Met) and genomic RNA of the yeast Ty1 retrotransposon Journal Article

In: Nucleic Acids Res, vol. 24, no. 3, pp. 441-9, 1996, (0305-1048 Journal Article).

Abstract | BibTeX | Tags: Acid, Base, cerevisiae, Conformation, Data, Gov't, Met/genetics/*metabolism, Molecular, Mutation, Non-U.S., Nucleic, Retroelements/*genetics, RNA, RNA/genetics/*metabolism, Saccharomyces, Sequence, structure, Support, Transfer

de Barros J. P. Pais, Keith G., Adlouni C. El, Glasser A. L., Mack G., Dirheimer G., Desgres J.

2'-O-methyl-5-formylcytidine (f5Cm), a new modified nucleotide at the 'wobble' of two cytoplasmic tRNAs Leu (NAA) from bovine liver Journal Article

In: Nucleic Acids Res, vol. 24, no. 8, pp. 1489-96, 1996, (0305-1048 Journal Article).

Abstract | BibTeX | Tags: &, Acid, Acyl/*chemistry/isolation, Amino, Animals, Base, Borohydrides/chemistry, Cattle, Cells, Conformation, Cytidine/*analogs, Cytoplasm, Data, derivatives/chemistry/isolation, Fragmentography, Gov't, Hela, Human, Liver/*chemistry, Mass, Molecular, Non-U.S., Nucleic, purification, RNA, Sequence, structure, Support, Transfer


Dirheimer G., Baranowski W., Keith G.

Variations in tRNA modifications, particularly of their queuine content in higher eukaryotes. Its relation to malignancy grading Journal Article

In: Biochimie, vol. 77, no. 1-2, pp. 99-103, 1995, (0300-9084 Journal Article Review Review, Tutorial).

Abstract | BibTeX | Tags: &, Animals, Cell, derivatives/analysis, Female, Gov't, Guanine/*analogs, Human, Neoplasms/*genetics/pathology, Neoplastic/genetics, Non-U.S., Ovarian, post-transcriptional, Processing, Purines/analysis, Pyrimidines/analysis, RNA, Support, Transfer/*chemistry/metabolism, Transformation

Gabryszuk J., Keith G., Monko M., Kuligowska E., Dirheimer G., Szarkowski J. W., Przykorska A.

Structural specificity of nuclease from wheat chloroplasts stroma Journal Article

In: Nucleic Acids Symp Ser, no. 33, pp. 115-9, 1995, (0261-3166 Journal Article).

Abstract | BibTeX | Tags: &, Acid, Asp/chemistry/genetics/metabolism, Base, Binding, Chloroplasts/*enzymology, Conformation, Data, Endonucleases/isolation, Fungal/chemistry/genetics/metabolism, Gov't, Molecular, Non-U.S., Nucleic, Phe/chemistry/genetics/metabolism, purification/*metabolism, RNA, RNA/chemistry/metabolism, Sequence, Sites, Specificity, Substrate, Support, Transfer, Triticum/*enzymology

Keith G.

Mobilities of modified ribonucleotides on two-dimensional cellulose thin-layer chromatography Journal Article

In: Biochimie, vol. 77, no. 1-2, pp. 142-4, 1995, (0300-9084 Journal Article).

BibTeX | Tags: *Chromatography, Layer, Purines/chemistry, Pyrimidines/chemistry, Ribonucleases/metabolism, Ribonucleotides/*chemistry, RNA, Thin, Transfer/chemistry

O'Connor M., Brunelli C. A., Firpo M. A., Gregory S. T., Lieberman K. R., Lodmell J. S., Moine H., Ryk D. I. Van, Dahlberg A. E.

Genetic probes of ribosomal RNA function Journal Article

In: Biochem Cell Biol, vol. 73, no. 11-12, pp. 859-68, 1995, (0829-8211 Journal Article Review Review, Tutorial).

Abstract | BibTeX | Tags: 16S/genetics, Acid, Base, Conformation, Data, Gov't, Messenger/genetics, Molecular, Mutation, Non-U.S., Nucleic, P.H.S., Probes, Ribosomal, Ribosomal/*genetics, RNA, Sequence, Support, Transfer/genetics, U.S.


Ferrandon Dominique, Elphick L, Nüsslein-Volhard C, Johnston St D

Staufen protein associates with the 3'UTR of bicoid mRNA to form particles that move in a microtubule-dependent manner Journal Article

In: Cell, vol. 79, no. 7, pp. 1221–1232, 1994, ISSN: 0092-8674.

Abstract | BibTeX | Tags: Animals, Base Sequence, Cell Polarity, ferrandon, Homeodomain Proteins, Insect Hormones, M3i, messenger, Microtubules, Nucleic Acid Conformation, Oocytes, RNA, RNA-Binding Proteins, Trans-Activators