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Publications

2024

Messmer Mélanie, Pierson Louison, Pasquier Charline, Djordjevic Nikola, Chicher Johana, Hammann Philippe, Pfeffer Sébastien, Girardi Erika

DEAD box RNA helicase 5 is a new pro-viral host factor for Sindbis virus infection Journal Article

In: Virol J, vol. 21, no. 1, pp. 76, 2024, ISSN: 1743-422X.

Abstract | Links | BibTeX | Tags: PFEFFER, PPSE, Unité ARN

Baldaccini Morgane, Gaucherand Léa, Chane-Woon-Ming Béatrice, Messmer Mélanie, Gucciardi Floriane, Pfeffer Sébastien

The helicase domain of human Dicer prevents RNAi-independent activation of antiviral and inflammatory pathways Journal Article

In: EMBO J, 2024, ISSN: 1460-2075.

Abstract | Links | BibTeX | Tags: PFEFFER, Unité ARN

2023

Gaucherand Lea, Iyer Amrita, Gilabert Isabel, Rycroft Chris H, Gaglia Marta M

Cut site preference allows influenza A virus PA-X to discriminate between host and viral mRNAs Journal Article

In: Nat Microbiol, 2023, ISSN: 2058-5276.

Abstract | Links | BibTeX | Tags: PFEFFER, Unité ARN

Girardi Erika, Messmer Mélanie, Lopez Paula, Fender Aurélie, Chicher Johana, Chane-Woon-Ming Béatrice, Hammann Philippe, Pfeffer Sébastien

Proteomics-based determination of double-stranded RNA interactome reveals known and new factors involved in Sindbis virus infection Journal Article

In: RNA, vol. 29, no. 3, pp. 361–375, 2023, ISSN: 1469-9001.

Abstract | Links | BibTeX | Tags: PFEFFER, PPSE, Unité ARN

Lee Seungjae, Jee David, Srivastava Sid, Yang Acong, Ramidi Abhinav, Shang Renfu, Bortolamiol-Becet Diane, Pfeffer Sébastien, Gu Shuo, Wen Jiayu, Lai Eric C

Promiscuous splicing-derived hairpins are dominant substrates of tailing-mediated defense of miRNA biogenesis in mammals Journal Article

In: Cell Rep, vol. 42, no. 2, pp. 112111, 2023, ISSN: 2211-1247.

Abstract | Links | BibTeX | Tags: PFEFFER, Unité ARN

2022

Girardi Erika, Messmer Melanie, Lopez Paula, Fender Aurelie, Chicher Johana, Chane-Woon-Ming Beatrice, Hammann Philippe, Pfeffer Sebastien

Proteomics-based determination of double stranded RNA interactome reveals known and new factors involved in Sindbis virus infection Journal Article

In: RNA, vol. 29, iss. 3, pp. 361-375, 2022, ISSN: 1469-9001.

Abstract | Links | BibTeX | Tags: PFEFFER, PPSE, Unité ARN

Vilimova Monika, Pfeffer Sébastien

Post-transcriptional regulation of polycistronic microRNAs Journal Article

In: Wiley Interdiscip Rev RNA, vol. 14, iss. 2, pp. e1749, 2022, ISSN: 1757-7012.

Abstract | Links | BibTeX | Tags: PFEFFER, Unité ARN

Camara A., Lavanant A. C., Abe J., Desforges H. L., Alexandre Y. O., Girardi E., Igamberdieva Z., Asano K., Tanaka M., Hehlgans T., Pfeffer K., Pfeffer S., Mueller S. N., Stein J. V., Mueller C. G.

CD169(+) macrophages in lymph node and spleen critically depend on dual RANK and LTbetaR signaling Journal Article

In: Proc Natl Acad Sci U S A, vol. 119, no. 3, pp. e2108540119, 2022, ISBN: 35031565, (1091-6490 (Electronic) 0027-8424 (Linking) Journal Article).

Abstract | Links | BibTeX | Tags: PFEFFER, Team-Mueller, Unité ARN

Brugier A., Hafirrassou M. L., Pourcelot M., Baldaccini M., Kril V., Couture L., Kummerer B. M., Gallois-Montbrun S., Bonnet-Madin L., Vidalain P. O., Delaugerre C., Pfeffer S., Meertens L., Amara A.

RACK1 Associates with RNA-Binding Proteins Vigilin and SERBP1 to Facilitate Dengue Virus Replication Journal Article

In: J Virol, vol. 96, iss. 7, pp. e0196221, 2022, ISBN: 35266803, (1098-5514 (Electronic) 0022-538X (Linking) Journal Article).

Abstract | Links | BibTeX | Tags: PFEFFER, Unité ARN

2021

Vilimova Monika, Contrant Maud, Randrianjafy Ramy, Dumas Philippe, Elbasani Endrit, Ojala Päivi M, Pfeffer Sébastien, Fender Aurélie

Correction to 'Cis regulation within a cluster of viral microRNAs' Miscellaneous

2021, ISSN: 1362-4962.

Links | BibTeX | Tags: PFEFFER, Unité ARN

Montavon T C, Baldaccini M, Lefevre M, Girardi E, Chane-Woon-Ming B, Messmer M, Hammann P, Chicher J, Pfeffer S

Human DICER helicase domain recruits PKR and modulates its antiviral activity Journal Article

In: PLoS Pathog, vol. 17, no. 5, pp. e1009549, 2021, ISBN: 33984068, (1553-7374 (Electronic) 1553-7366 (Linking) Journal Article).

Abstract | Links | BibTeX | Tags: PFEFFER, PPSE, Unité ARN

Vilimova M, Contrant M, Randrianjafy R, Dumas P, Elbasani E, Ojala P M, Pfeffer S, Fender A

Cis regulation within a cluster of viral microRNAs Journal Article

In: Nucleic Acids Res, 2021, ISBN: 34417603, (1362-4962 (Electronic) 0305-1048 (Linking) Journal Article).

Abstract | Links | BibTeX | Tags: PFEFFER, Unité ARN

Baldaccini M., Pfeffer S.

Untangling the roles of RNA helicases in antiviral innate immunity Journal Article

In: PLoS Pathog, vol. 17, no. 12, pp. e1010072, 2021, ISBN: 34882751, (1553-7374 (Electronic) 1553-7366 (Linking) Journal Article Review).

Abstract | Links | BibTeX | Tags: PFEFFER, Unité ARN

2020

Petitjean O, Girardi E, Ngondon RP, Lupashin V, Pfeffer S

Genome-Wide CRISPR-Cas9 Screen Reveals the Importance of the Heparan Sulfate Pathway and the Conserved Oligomeric Golgi Complex for Synthetic Double-Stranded RNA Uptake and Sindbis Virus Infection Journal Article

In: mSphere, vol. 5, no. 6, pp. e00914-20, 2020.

Abstract | Links | BibTeX | Tags: complex oligomeric Golgi complex, CRISPR-Cas9 screen, double-stranded RNA, heparan-sulfate, PFEFFER, Transfection, Unité ARN, virus

Lopez P, Girardi E, Mounce B C, Weiss A, Chane-Woon-Ming B, Messmer M, Kaukinen P, Kopp A, Bortolamiol-Becet D, Fendri A, Vignuzzi M, Brino L, Pfeffer S

High-throughput Fluorescence-Based Screen Identifies the Neuronal microRNA miR-124 as a Positive Regulator of Alphavirus Infection Journal Article

In: J Virol, vol. 94, no. 9, pp. e02145-02119, 2020, ISBN: 32102877.

Abstract | Links | BibTeX | Tags: PFEFFER, Unité ARN

Herzog K, Bandiera S, Pernot S, Fauvelle C, Jühling F, Weiss A, Bull A, Durand S C, Chane-Woon-Ming B, Pfeffer S, Mercey M, Lerat H, Meunier J C, Raffelsberger W, Brino L, Baumert T F, Zeisel M B

Functional microRNA screen uncovers O-linked N-acetylglucosamine transferase as a host factor modulating hepatitis C virus morphogenesis and infectivity Journal Article

In: Gut, vol. 69, no. 2, pp. 380-392, 2020, ISBN: 31076402.

Abstract | Links | BibTeX | Tags: HCV hepatitis C hepatocyte molecular mechanisms, PFEFFER, Unité ARN

Girardi E, Pfeffer S, Baumert T F, Majzoub K

Roadblocks and fast tracks: How RNA binding proteins affect the viral RNA journey in the cell Journal Article

In: Semin Cell Dev Biol, vol. S1084-9521, no. 20, pp. 30091-4, 2020, ISBN: 32847707.

Abstract | Links | BibTeX | Tags: Innate Immunity RNA biology RNA viruses Technology Viral RNA sensing Viral Translation Virology., PFEFFER, Unité ARN

Ghosh S, Guimaraes J C, Lanzafame M, Schmidt A, Syed A P, Dimitriades B, Börsch A, Ghosh S, Mittal N, Montavon T, Correia A L, Danner J, Meister G, Terracciano L M, Pfeffer S, Piscuoglio S, Zavolan M

Prevention of dsRNA-induced interferon signaling by AGO1x is linked to breast cancer cell proliferation Journal Article

In: EMBO J, pp. in press, 2020, ISBN: 32812257.

Abstract | Links | BibTeX | Tags: Argonaute 1 breast cancer endogenous dsRNA interferon response translation readthrough, PFEFFER, Unité ARN

2019

Spaety M E, Gries A, Badie A, Venkatasamy A, Romain B, Orvain C, Yanagihara K, Okamoto K, Jung A C, Mellitzer G, Pfeffer S, Gaiddon C

HDAC4 Levels Control Sensibility toward Cisplatin in Gastric Cancer via the p53-p73/BIK Pathway Journal Article

In: Cancers (Basel), vol. 11, no. 11, pp. 1747, 2019, ISBN: 31703394.

Abstract | Links | BibTeX | Tags: BIK HDAC4 cisplatin gastric cancer miR-140 p53 p73, PFEFFER, Unité ARN

Lopez P, Girardi E, Pfeffer S

[Importance of cellular microRNAs in the regulation of viral infections] Journal Article

In: Med Sci (Paris), vol. 35, no. 8-9, pp. 667-673, 2019, ISBN: 31532379.

Abstract | Links | BibTeX | Tags: PFEFFER, Unité ARN

2018

Olivier Petitjean Thomas Montavon, Pfeffer Sébastien

To have and have not, RNA interference as an antiviral defense system in mammals Journal Article

In: Virologie (Montrouge), vol. 22, no. 5, pp. 251-260, 2018, ISSN: 33111686 .

Abstract | Links | BibTeX | Tags: PFEFFER, Unité ARN

Girardi E, López P, Pfeffer S

On the Importance of Host MicroRNAs During Viral Infection Journal Article

In: Front Genet, vol. 9, pp. 439, 2018, ISBN: 30333857.

Abstract | Links | BibTeX | Tags: defense mechanism host–pathogen interaction microRNA post-transcriptional regulation virus, PFEFFER, Unité ARN

Creugny A, Fender A, Pfeffer S

Regulation of primary-microRNA processing Journal Article

In: FEBS Lett, vol. 592, no. 12, pp. 1980-1996, 2018, ISBN: 29683487.

Abstract | Links | BibTeX | Tags: Drosha biogenesis microRNA regulation, PFEFFER, Unité ARN

Bortolamiol-Bécet D, Monsion B, Chapuis S, Hleibieh K, Scheidecker D, Alioua A, Bogaert F, Revers F, Brault V, Ziegler-Graff V

Phloem-Triggered Virus-Induced Gene Silencing Using a Recombinant Polerovirus Journal Article

In: Front Microbiol, vol. 9, pp. 2449, 2018, ISBN: 30405546.

Abstract | Links | BibTeX | Tags: PFEFFER, Unité ARN, VIGS phloem polerovirus suppressor of RNA silencing visual monitoring of infection

2016

Alsaleh G, Nehmar R, Blüml S, Schleiss C, Ostermann E, Dillenseger J P, Sayeh A, Choquet P, Dembele D, Francois A, Salmon J H, Paul N, Schabbauer G, Bierry G, Meyer A, Gottenberg J E, Haas G, Pfeffer S, Vallat L, Sibilia J, Bahram S, Georgel P

Reduced DICER1 expression bestows rheumatoid arthritis synoviocytes proinflammatory properties and resistance to apoptotic stimuli. Journal Article

In: Arthritis Rheumatol, vol. 68, no. 8, pp. 1839-1848, 2016, ISBN: 26882526.

Abstract | Links | BibTeX | Tags: DICER1 inflammation microRNA rheumatoid arthritis, PFEFFER, Unité ARN

Haas G, Cetin S, Messmer M, Chane-Woon-Ming B, Terenzi O, Chicher J, Kuhn L, Hammann P, Pfeffer S

Identification of factors involved in target RNA-directed microRNA degradation. Journal Article

In: Nucleic Acids Res, vol. 44, no. 6, pp. 2873-2887, 2016, ISBN: 26809675.

Abstract | Links | BibTeX | Tags: PFEFFER, PPSE, Unité ARN

Haar J, Contrant M, Bernhardt K, Feederle R, Diederichs S, Pfeffer S, Delecluse H J

The expression of a viral microRNA is regulated by clustering to allow optimal B cell transformation. Journal Article

In: Nucleic Acids Res, vol. 44, no. 3, pp. 1326-1341, 2016, ISBN: 26635399.

Abstract | Links | BibTeX | Tags: PFEFFER, Unité ARN

2015

Sorel O, Tuddenham L, Myster F, Palmeira L, Kerkhofs P, Pfeffer S, Vanderplasschen A, Dewals B G

Small RNA deep sequencing identifies viral microRNAs during malignant catarrhal fever induced by alcelaphine herpesvirus 1. Journal Article

In: J Gen Virol, vol. 96, no. 11, pp. 3360-3372, 2015, ISBN: 26329753.

Abstract | Links | BibTeX | Tags: PFEFFER, Unité ARN

Oussaief L, Fendri A, Chane-Woon-Ming B, Poirey R, Delecluse H J, Joab I, Pfeffer S

Modulation of the microRNA cluster miR-183-96-182 expression by the Epstein-Barr virus latent membrane protein 1. Journal Article

In: J Virol, vol. 89, no. 23, pp. 12178-12188, 2015, ISBN: 26401047.

Abstract | Links | BibTeX | Tags: PFEFFER, Unité ARN

Mailly L, Xiao F, Lupberger J, Wilson G K, Aubert P, Duong F H, Calabrese D, Leboeuf C, Fofana I, Thumann C, Bandiera S, Lütgehetmann M, Volz T, Davis C, Harris H J, Mee C J, Girardi E, Chane-Woon-Ming B, Ericsson M, Fletcher N, Bartenschlager R, Pessaux P, Vercauteren K, Meuleman P, Villa P, Kaderali L, Pfeffer S, Heim M H, Neunlist M, Zeisel M B, Dandri M, McKeating J A, Robinet E, Baumert T F

Clearance of persistent hepatitis C virus infection in humanized mice using a claudin-1-targeting monoclonal antibody. Journal Article

In: Nat Biotechnol, vol. 33, no. 5, pp. 549-554, 2015, ISBN: 25798937.

Abstract | Links | BibTeX | Tags: PFEFFER, Unité ARN

Girardi E, Lefèvre M, Chane-Woon-Ming B, Paro S, Claydon B, Imler JL, Meignin C, Pfeffer S

Cross-species comparative analysis of Dicer proteins during Sindbis virus infection. Journal Article

In: Sci Rep, vol. 5, pp. 10693, 2015, ISBN: 26024431.

Abstract | Links | BibTeX | Tags: meignin, PFEFFER, Unité ARN

Bandiera S, Pfeffer S, Baumert T F, Zeisel M B

miR-122 - a key factor and therapeutic target in liver disease. Journal Article

In: J Hepatol, vol. 62, no. 2, pp. 448-457, 2015, ISBN: 25308172.

Abstract | Links | BibTeX | Tags: HBV HCC HCV Hepatitis Liver disease pathogenesis miR-122, PFEFFER, Unité ARN

2014

Stik G, Muylkens B, Coupeau D, Laurent S, Dambrine G, Messmer M, Chane-Woon-Ming B, Pfeffer S, Rasschaert D

Small RNA cloning and sequencing strategy affects host and viral microRNA expression signatures Journal Article

In: J Biotechnol, vol. 181, pp. 35-44, 2014, ISBN: 24746587.

Abstract | Links | BibTeX | Tags: Marek's disease virus MicroRNA Small RNA cloning and sequencing Viral infection, PFEFFER, Unité ARN

Pfeffer S

Herpesviruses Encode Their Own MicroRNAs. Journal Article

In: Clin Chem, vol. 60, no. 5, pp. 791-792, 2014, ISBN: 24778302.

Links | BibTeX | Tags: PFEFFER, Unité ARN

2012

Tuddenham L, Jung J S, Chane-Woon-Ming B, Dölken L, Pfeffer S

Small RNA deep-sequencing identifies microRNAs and other small non-coding RNAs from human herpesvirus 6 (HHV-6B). Journal Article

In: J Virol, vol. 86, pp. 1638-1649, 2012, ISBN: 22114334, (Published ahead of print 23 November 2011).

Abstract | Links | BibTeX | Tags: MicroRNA Roseolovirus HHV-6 Sup-T-1 OriLyt, PFEFFER, Unité ARN

Philippe L, Alsaleh G, Suffert G, Meyer A, Georgel P, Sibilia J, Wachsmann D, Pfeffer S

TLR2 Expression Is Regulated by MicroRNA miR-19 in Rheumatoid Fibroblast-like Synoviocytes. Journal Article

In: J Immunol, vol. 188, no. 1, pp. 454-461, 2012, ISBN: 22105995, (Published online: November 21, 2011).

Abstract | Links | BibTeX | Tags: PFEFFER, Unité ARN

Ostermann E, Tuddenham L, Macquin C, Alsaleh G, Schreiber-Becker J, Tanguy M, Bahram S, Pfeffer S, Georgel P

Deregulation of Type I IFN-Dependent Genes Correlates with Increased Susceptibility to Cytomegalovirus Acute Infection of Dicer Mutant Mice. Journal Article

In: PLoS One, vol. 7, no. 8, pp. e43744, 2012, ISBN: 22916300.

Abstract | Links | BibTeX | Tags: PFEFFER, Unité ARN

Marcinowski L, Tanguy M, Krmpotic A, Rädle B, Lisnić V J, Tuddenham L, Chane-Woon-Ming B, Ruzsics Z, Erhard F, Benkartek C, Babic M, Zimmer R, Trgovcich J, Koszinowski U H, Jonjic S, Pfeffer S, Dölken L

Degradation of cellular mir-27 by a novel, highly abundant viral transcript is important for efficient virus replication in vivo. Journal Article

In: PLoS Pathog, vol. 8, no. 2, pp. e1002510, 2012, ISBN: 22346748.

Abstract | Links | BibTeX | Tags: PFEFFER, Unité ARN

Costa D Da, Turek M, Felmlee D J, Girardi E, Pfeffer S, Long G, Bartenschlager R, Zeisel M B, Baumert T F

Reconstitution of the entire hepatitis C virus life cycle in non-hepatic cells. Journal Article

In: J Virol, vol. 86, no. 21, pp. 11919-11925, 2012, ISBN: 22896615.

Abstract | Links | BibTeX | Tags: PFEFFER, Unité ARN