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2021

Prakash Pragya, Roychowdhury-Sinha Arghyashree, Goto Akira

Verloren negatively regulates the expression of IMD pathway dependent antimicrobial peptides in Drosophila Article de journal

Dans: Scientific Reports, 11 (15549), 2021.

Résumé | Liens | BibTeX | Étiquettes: bacteria, Biochemistry, DNA, Fungi, Gene Expression, gene regulation, Genetics, hoffmann, Immunochemistry, Immunology, infection, inflammation, Innate immune cells, innate immunity, M3i, microbiology, Molecular Biology, pathogens, RNA, RNAi, Signal Transduction, Transcription

Chen Di, Roychowdhury-Sinha Arghyashree, Prakash Pragya, Lan Xiao, Fan Wenmin, Goto Akira, Hoffmann Jules A.

A time course transcriptomic analysis of host and injected oncogenic cells reveals new aspects of Drosophila immune defenses Article de journal

Dans: PNAS, 118 (12), 2021.

Résumé | Liens | BibTeX | Étiquettes: cancer, chemoreceptor, Drosophila melanogaster, goto, hoffmann, innate immunity, M3i, RasV12

2020

Imler JL, Hofmann JA

L'immunité innée Chapitre d'ouvrage

Dans: Cramer, P; Meignien, A (Ed.): Le défi des maladies infectieuses , p. 191-203, Les éditions du Palais, Docis, 2020, ISBN: 9791090119895.

BibTeX | Étiquettes: hoffmann, imler, M3i

Goto Akira, Okado Kiyoshi, Martins Nelson, Cai Hua, Barbier Vincent, Lamiable Olivier, Troxler Laurent, Santiago Estelle, Kuhn Lauriane, Paik Donggi, Silverman Neal, Holleufer Andreas, Hartmann Rune, Liu Jiyong, Peng Tao, Hoffmann Jules A, Meignin Carine, Daeffler Laurent, Imler Jean-Luc

The Kinase IKKβ Regulates a STING-and NF-κB-Dependent Antiviral Response Pathway in Drosophila Article de journal

Dans: Immunity, 52 (1), p. 200, 2020.

Résumé | Liens | BibTeX | Étiquettes: antiviral, Drosophila, hoffmann, imler, Kinase, M3i, meignin, STING

2018

Goto Akira, Okado Kiyoshi, Martins Nelson, Cai Hua, Barbier Vincent, Lamiable Olivier, Troxler Laurent, Santiago Estelle, Kuhn Lauriane, Paik Donggi, Silverman Neal, Holleufer Andreas, Hartmann Rune, Liu Jiyong, Peng Tao, Hoffmann Jules A, Meignin Carine, Daeffler Laurent, Imler Jean-Luc

The Kinase IKKβ Regulates a STING- and NF-κB-Dependent Antiviral Response Pathway in Drosophila Article de journal

Dans: Immunity, (49), p. 225-234, 2018.

Résumé | Liens | BibTeX | Étiquettes: hoffmann, imler, M3i, meignin, PPSE

2016

Lamiable Olivier, Kellenberger Christine, Kemp Cordula, Troxler Laurent, Pelte Nadège, Boutros Michael, Marques Joao Trindade, Daeffler Laurent, Hoffmann Jules A, Roussel Alain, Imler Jean-Luc

Cytokine Diedel and a viral homologue suppress the IMD pathway in Drosophila Article de journal

Dans: PNAS, 113 (3), p. 698–703, 2016, ISSN: 0027-8424, 1091-6490.

Résumé | Liens | BibTeX | Étiquettes: antiviral immunity, bioinformatic, cytokine, Edin, hoffmann, imler, M3i, Sindbis Virus, virokine

Lamiable Olivier, Arnold Johan, da de Faria Isaque Joao Silva, Olmo Roenick Proveti, Bergami Francesco, Meignin Carine, Hoffmann Jules A, Marques Joao Trindade, Imler Jean-Luc

Analysis of the Contribution of Hemocytes and Autophagy to Drosophila Antiviral Immunity Article de journal

Dans: J. Virol., 90 (11), p. 5415–5426, 2016, ISSN: 0022-538X, 1098-5514.

Liens | BibTeX | Étiquettes: antiviral immunity, Autophagy, Hemocytes, hoffmann, imler, M3i, meignin

2014

Chtarbanova Stanislava, Lamiable Olivier, Lee Kwang-Zin, Galiana Delphine, Troxler Laurent, Meignin Carine, Hetru Charles, Hoffmann Jules A, Daeffler Laurent, Imler Jean-Luc

Drosophila C virus systemic infection leads to intestinal obstruction Article de journal

Dans: Journal of Virology, 88 (24), p. 14057–14069, 2014, ISSN: 1098-5514.

Résumé | Liens | BibTeX | Étiquettes: Animals, bioinformatic, Dicistroviridae, Female, Gastrointestinal Tract, Gene Expression Profiling, hoffmann, imler, Intestinal Obstruction, M3i, meignin, Muscle, Nodaviridae, Sindbis Virus, Smooth, Viral Tropism

Tartey Sarang, Matsushita Kazufumi, Vandenbon Alexis, Ori Daisuke, Imamura Tomoko, Mino Takashi, Standley Daron M, Hoffmann Jules A, Reichhart Jean-Marc, Akira Shizuo, Takeuchi Osamu

Akirin2 is critical for inducing inflammatory genes by bridging IκB-ζ and the SWI/SNF complex Article de journal

Dans: EMBO J., 33 (20), p. 2332–2348, 2014, ISSN: 1460-2075.

Résumé | Liens | BibTeX | Étiquettes: Adaptor Proteins, Animals, Cell Nucleus, Chromatin Assembly and Disassembly, chromatin remodeling, Chromosomal Proteins, cytokine, Cytokines, Female, Gene Expression Regulation, gene regulation, Genetic, hoffmann, Humans, Immunity, Innate, innate immunity, Knockout, Listeria monocytogenes, M3i, Macrophages, Male, Mice, Multiprotein Complexes, Non-Histone, Nuclear Proteins, Promoter Regions, Protein Binding, reichhart, Repressor Proteins, Sequence Deletion, Signal Transducing, Transcriptional Activation

Goto Akira, Fukuyama Hidehiro, Imler Jean-Luc, Hoffmann Jules A

The chromatin regulator DMAP1 modulates activity of the nuclear factor B (NF-B) transcription factor Relish in the Drosophila innate immune response Article de journal

Dans: The Journal of Biological Chemistry, 289 (30), p. 20470–20476, 2014, ISSN: 1083-351X.

Résumé | Liens | BibTeX | Étiquettes: Animals, Cell Line, Chromatin Assembly and Disassembly, Epistasis, Escherichia coli, Escherichia coli Infections, Genetic, hoffmann, imler, Immunity, Innate, M3i, NF-kappa B, Repressor Proteins, Signal Transduction, Transcription Factors

Imler Jean-Luc, Hoffmann Jules A

Le défi des maladies infectieuses Chapitre d'ouvrage

Dans: collection Guérir et prévenir demain, Ph. Cramer (Ed.): Chapitre « L’immunité innée », p. 167-174, Editions DOCIS, 2014, ISBN: 978-2-85525-390-9.

Résumé | BibTeX | Étiquettes: hoffmann, imler, innate immunity, M3i, maladies infectieuses

Majzoub K, Hafirassou M L, Meignin C, Goto A, Marzi S, Fedorova A, Verdier Y, Vinh J, Hoffmann J A, Martin F, Baumert T F, Schuster C, Imler JL

RACK1 Controls IRES-Mediated Translation of Viruses. Article de journal

Dans: Cell, 159 (5), p. 1086-1095, 2014, ISBN: 25416947.

Résumé | Liens | BibTeX | Étiquettes: ERIANI, hoffmann, imler, M3i, meignin, ROMBY, Unité ARN

2013

Fukuyama Hidehiro, Verdier Yann, Guan Yongsheng, Makino-Okamura Chieko, Shilova Victoria, Liu Xi, Maksoud Elie, Matsubayashi Jun, Haddad Iman, Spirohn Kerstin, Ono Kenichiro, Hetru Charles, Rossier Jean, Ideker Trey, Boutros Michael, Vinh Joëlle, Hoffmann Jules A

Landscape of protein-protein interactions in Drosophila immune deficiency signaling during bacterial challenge Article de journal

Dans: Proc. Natl. Acad. Sci. U.S.A., 110 (26), p. 10717–10722, 2013, ISSN: 1091-6490.

Résumé | Liens | BibTeX | Étiquettes: Amino Acid, Animals, Chromatin Assembly and Disassembly, Escherichia coli, functional proteomics, Genes, Genetically Modified, Histone Acetyltransferases, hoffmann, Host-Pathogen Interactions, Humans, IMD interactome, Insect, M3i, Models, Molecular, Protein Interaction Maps, Sequence Homology, Signal Transduction, small ubiquitin-like modifier

Bonnay François, Cohen-Berros Eva, Hoffmann Martine, Kim Sabrina Y, Boulianne Gabrielle L, Hoffmann Jules A, Matt Nicolas, Reichhart Jean-Marc

Big bang gene modulates gut immune tolerance in Drosophila Article de journal

Dans: Proc. Natl. Acad. Sci. U.S.A., 110 (8), p. 2957–2962, 2013, ISSN: 1091-6490.

Résumé | Liens | BibTeX | Étiquettes: Animals, hoffmann, Immune Tolerance, Longevity, M3i, matt, Membrane Proteins, reichhart

2012

Lemaitre Bruno, Nicolas Emmanuelle, Michaut Lydia, Reichhart Jean-Marc, Hoffmann Jules A

Pillars article: the dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults. Cell. 1996. 86: 973-983 Article de journal

Dans: J. Immunol., 188 (11), p. 5210–5220, 2012, ISSN: 1550-6606.

Résumé | BibTeX | Étiquettes: Animals, Antifungal Agents, Developmental, DNA-Binding Proteins, Gene Expression Regulation, history, hoffmann, M3i, Multigene Family, Mycoses, Phosphoproteins, reichhart, Toll-Like Receptors

Imler Jean-Luc, Hoffmann Jules A

Nucleic Acid Sensors and Antiviral Immunity Chapitre d'ouvrage

Dans: eds T. Fujita & P. Sambhara, (Ed.): Chapitre 1 : Antiviral responses in invertebrates, p. 1-18, Landes Bioscience, 2012.

BibTeX | Étiquettes: antiviral immunity, hoffmann, imler, Invertebrate, M3i

Liu Xi, Sano Teruyuki, Guan Yongsheng, Nagata Shigekazu, Hoffmann Jules A, Fukuyama Hidehiro

Drosophila EYA regulates the immune response against DNA through an evolutionarily conserved threonine phosphatase motif Article de journal

Dans: PLoS ONE, 7 (8), p. e42725, 2012, ISSN: 1932-6203.

Résumé | Liens | BibTeX | Étiquettes: Amino Acid, Animals, Blotting, Conserved Sequence, Endodeoxyribonucleases, Eye Proteins, hoffmann, Immunoprecipitation, M3i, Phosphoprotein Phosphatases, Sequence Homology, Transcription Factors, Western

2011

Eleftherianos Ioannis, Won Sungyong, Chtarbanova Stanislava, Squiban Barbara, Ocorr Karen, Bodmer Rolf, Beutler Bruce, Hoffmann Jules A, Imler Jean-Luc

ATP-sensitive potassium channel (K(ATP))-dependent regulation of cardiotropic viral infections Article de journal

Dans: Proceedings of the National Academy of Sciences of the United States of America, 108 (29), p. 12024–12029, 2011, ISSN: 1091-6490.

Résumé | Liens | BibTeX | Étiquettes: Animals, Heart, HeLa Cells, hoffmann, Humans, imler, Immunity, Immunoblotting, Inbred C57BL, Innate, KATP Channels, M3i, Mice, Nodaviridae, Pinacidil, Reverse Transcriptase Polymerase Chain Reaction, RNA Interference, Tolbutamide, Viral Load, Viremia

2009

Hetru Charles, Hoffmann Jules A

NF-kappaB in the immune response of Drosophila Article de journal

Dans: Cold Spring Harb Perspect Biol, 1 (6), p. a000232, 2009, ISSN: 1943-0264.

Résumé | Liens | BibTeX | Étiquettes: Animals, bacteria, Fungi, Gene Expression Regulation, hoffmann, M3i, NF-kappa B

Mishima Yumiko, Quintin Jessica, Aimanianda Vishukumar, Kellenberger Christine, Coste Franck, Clavaud Cecile, Hetru Charles, Hoffmann Jules A, Latgé Jean-Paul, Ferrandon Dominique, Roussel Alain

The N-terminal domain of Drosophila Gram-negative binding protein 3 (GNBP3) defines a novel family of fungal pattern recognition receptors Article de journal

Dans: J. Biol. Chem., 284 (42), p. 28687–28697, 2009, ISSN: 1083-351X.

Résumé | Liens | BibTeX | Étiquettes: Animals, beta-Glucans, Bombyx, Carrier Proteins, Crystallography, ferrandon, Fungal Proteins, Hemolymph, hoffmann, ligands, M3i, Molecular Conformation, Mutagenesis, Polysaccharides, Protein Structure, Secondary, Tertiary, X-Ray

Fraiture Malou, Baxter Richard H G, Steinert Stefanie, Chelliah Yogarany, Frolet Cécile, Quispe-Tintaya Wilber, Hoffmann Jules A, Blandin Stéphanie A, Levashina Elena A

Two mosquito LRR proteins function as complement control factors in the TEP1-mediated killing of Plasmodium Article de journal

Dans: Cell Host Microbe, 5 (3), p. 273–284, 2009, ISSN: 1934-6069.

Résumé | Liens | BibTeX | Étiquettes: Animals, Anopheles, APL1, Biological, blandin, Complement System Proteins, Hemolymph, hoffmann, Immunologic Factors, LRIM1, M3i, Models, Plasmodium, Protein Binding, Proteins, TEP1

2008

Deddouche Safia, Matt Nicolas, Budd Aidan, Mueller Stefanie, Kemp Cordula, Galiana-Arnoux Delphine, Dostert Catherine, Antoniewski Christophe, Hoffmann Jules A, Imler Jean-Luc

The DExD/Ħ-box helicase Dicer-2 mediates the induction of antiviral activity in drosophila Article de journal

Dans: Nature Immunology, 9 (12), p. 1425–1432, 2008, ISSN: 1529-2916.

Résumé | Liens | BibTeX | Étiquettes: Amino Acid, Animals, Electrophoresis, Fat Body, Gene Expression Regulation, Genetic, Genetically Modified, hoffmann, Humans, imler, M3i, matt, Phylogeny, Polyacrylamide Gel, Reverse Transcriptase Polymerase Chain Reaction, Ribonuclease III, RNA Helicases, Sequence Homology, Transcription, Virus Diseases

Goto Akira, Matsushita Kazufumi, Gesellchen Viola, Chamy Laure El, Kuttenkeuler David, Takeuchi Osamu, Hoffmann Jules A, Akira Shizuo, Boutros Michael, Reichhart Jean-Marc

Akirins are highly conserved nuclear proteins required for NF-kappaB-dependent gene expression in drosophila and mice Article de journal

Dans: Nat. Immunol., 9 (1), p. 97–104, 2008, ISSN: 1529-2916.

Résumé | Liens | BibTeX | Étiquettes: Animals, Cell Line, Embryo, Fibroblasts, hoffmann, Humans, Immunity, Innate, Interleukin-1beta, M3i, Mammalian, Mice, NF-kappa B, Nuclear Proteins, Proteins, reichhart, Signal Transduction, Toll-Like Receptors, transgenic, Tumor Necrosis Factor-alpha

2007

Ferrandon Dominique, Imler Jean-Luc, Hetru Charles, Hoffmann Jules A

The Drosophila systemic immune response: sensing and signalling during bacterial and fungal infections Article de journal

Dans: Nat Rev Immunol, 7 , p. 862–74, 2007.

Résumé | BibTeX | Étiquettes: Animals, Bacterial Infections/*immunology/microbiology, Drosophila melanogaster/genetics/*immunology/microbiology, ferrandon, hoffmann, imler, Immunity, M3i, Mycoses/*immunology/microbiology, Natural/genetics, Signal Transduction/genetics/*immunology

Beutler Bruce, Eidenschenk Celine, Crozat Karine, Imler Jean-Luc, Takeuchi Osamu, Hoffmann Jules A, Akira Shizuo

Genetic analysis of resistance to viral infection Article de journal

Dans: Nature Reviews. Immunology, 7 (10), p. 753–766, 2007, ISSN: 1474-1741.

Résumé | Liens | BibTeX | Étiquettes: Animals, Antiviral Agents, Disease Susceptibility, Drug Resistance, Eukaryotic Cells, hoffmann, Humans, imler, Immunity, M3i, Mutation, Viral, Virus Diseases, viruses

Nehme Nadine T, Liégeois Samuel, Kele Beatrix, Giammarinaro Philippe, Pradel Elizabeth, Hoffmann Jules A, Ewbank Jonathan J, Ferrandon Dominique

A model of bacterial intestinal infections in Drosophila melanogaster Article de journal

Dans: PLoS Pathog., 3 (11), p. e173, 2007, ISSN: 1553-7374.

Résumé | Liens | BibTeX | Étiquettes: Animal, Animals, Disease Models, Electron, ferrandon, fluorescence, Hemolymph, hoffmann, Host-Pathogen Interactions, Immunohistochemistry, Intestines, M3i, Microscopy, Reverse Transcriptase Polymerase Chain Reaction, Serratia Infections, Serratia marcescens, Transmission

2006

Gottar Marie, Gobert Vanessa, Matskevich Alexey A, Reichhart Jean-Marc, Wang Chengshu, Butt Tariq M, Belvin Marcia, Hoffmann Jules A, Ferrandon Dominique

Dual detection of fungal infections in Drosophila via recognition of glucans and sensing of virulence factors Article de journal

Dans: Cell, 127 (7), p. 1425–1437, 2006, ISSN: 0092-8674.

Résumé | Liens | BibTeX | Étiquettes: Animals, Antibody Formation, Beauveria, Candida albicans, Carrier Proteins, Cellular, ferrandon, Glucans, hoffmann, Immunity, Immunological, M3i, Metarhizium, Models, Polysaccharides, reichhart, Serine Endopeptidases, Signal Transduction, Virulence Factors

Shiao Shin-Hong, Whitten Miranda M A, Zachary Daniel, Hoffmann Jules A, Levashina Elena A

Fz2 and cdc42 mediate melanization and actin polymerization but are dispensable for Plasmodium killing in the mosquito midgut Article de journal

Dans: PLoS Pathog., 2 (12), p. e133, 2006, ISSN: 1553-7374.

Résumé | Liens | BibTeX | Étiquettes: Actins, Animals, Anopheles, Carrier Proteins, cdc42 GTP-Binding Protein, Double-Stranded, Electron, Frizzled Receptors, Gastrointestinal Tract, hoffmann, Host-Parasite Interactions, Immunity, Innate, Insect Vectors, Intestinal Mucosa, M3i, Melanins, Microarray Analysis, Microscopy, Plasmodium berghei, Polymers, Protozoan, RNA, scanning, telomerase

Frolet Cécile, Thoma Martine, Blandin Stéphanie A, Hoffmann Jules A, Levashina Elena A

Boosting NF-kappaB-dependent basal immunity of Anopheles gambiae aborts development of Plasmodium berghei Article de journal

Dans: Immunity, 25 (4), p. 677–685, 2006, ISSN: 1074-7613.

Résumé | Liens | BibTeX | Étiquettes: Animals, Anopheles gambiae, blandin, Gene Expression, Gene Expression Regulation, Genes, hoffmann, Immunity, Insect, M3i, NF-kappa B, Plasmodium berghei, telomerase

Galiana-Arnoux Delphine, Dostert Catherine, Schneemann Anette, Hoffmann Jules A, Imler Jean-Luc

Essential function in vivo for Dicer-2 in host defense against RNA viruses in drosophila Article de journal

Dans: Nature Immunology, 7 (6), p. 590–597, 2006, ISSN: 1529-2908.

Résumé | Liens | BibTeX | Étiquettes: Animals, Genetically Modified, hoffmann, imler, M3i, Mutation, Nodaviridae, Ribonuclease III, RNA, RNA Helicases, RNA Interference, RNA Viruses, Viral, Viral Proteins, Virus Replication

Bischoff Vincent, Vignal Cécile, Duvic Bernard, Boneca Ivo G, Hoffmann Jules A, Royet Julien

Downregulation of the Drosophila immune response by peptidoglycan-recognition proteins SC1 and SC2 Article de journal

Dans: PLoS Pathog., 2 (2), p. e14, 2006, ISSN: 1553-7374.

Résumé | Liens | BibTeX | Étiquettes: Animals, Antimicrobial Cationic Peptides, bacteria, Carrier Proteins, Down-Regulation, hoffmann, Larva, M3i, RNA Interference, Signal Transduction

Leclerc Vincent, Pelte Nadège, Chamy Laure El, Martinelli Cosimo, Ligoxygakis Petros, Hoffmann Jules A, Reichhart Jean-Marc

Prophenoloxidase activation is not required for survival to microbial infections in Drosophila Article de journal

Dans: EMBO Rep., 7 (2), p. 231–235, 2006, ISSN: 1469-221X.

Résumé | Liens | BibTeX | Étiquettes: Animals, Bacterial Infections, Catechol Oxidase, Enzyme Activation, Enzyme Precursors, Gram-Negative Bacteria, Gram-Positive Bacteria, Hemolymph, hoffmann, Immunity, Innate, M3i, Mutation, reichhart, Survival Rate

2005

Kocks Christine, Cho Ju Hyun, Nehme Nadine, Ulvila Johanna, Pearson Alan M, Meister Marie, Strom Charles, Conto Stephanie L, Hetru Charles, Stuart Lynda M, Stehle Thilo, Hoffmann Jules A, Reichhart Jean-Marc, Ferrandon Dominique, Rämet Mika, Ezekowitz Alan R B

Eater, a transmembrane protein mediating phagocytosis of bacterial pathogens in Drosophila Article de journal

Dans: Cell, 123 (2), p. 335–346, 2005, ISSN: 0092-8674.

Résumé | Liens | BibTeX | Étiquettes: Amino Acid, Amino Acid Motifs, Animals, Bacterial Infections, Cell Surface, Embryo, Escherichia coli, ferrandon, Flow Cytometry, Frameshift Mutation, Genes, Histidine, hoffmann, In Situ Hybridization, Insect, Insect Proteins, M3i, Macrophages, Membrane Proteins, messenger, Nonmammalian, Open Reading Frames, Phagocytosis, Receptors, reichhart, RNA, RNA Interference, Sequence Homology, Serratia marcescens

Irving Phil, Ubeda Jean-Michel, Doucet Daniel, Troxler Laurent, Lagueux Marie, Zachary Daniel, Hoffmann Jules A, Hetru Charles, Meister Marie

New insights into Drosophila larval haemocyte functions through genome-wide analysis Article de journal

Dans: Cell. Microbiol., 7 (3), p. 335–350, 2005, ISSN: 1462-5814.

Résumé | Liens | BibTeX | Étiquettes: Animals, bioinformatic, Catechol Oxidase, Cell Lineage, Enzyme Precursors, Escherichia coli, Fat Body, Gene Expression Profiling, Genome, Hemocytes, hoffmann, Integrin alpha Chains, Integrins, Larva, M3i, Micrococcus luteus

Royet Julien, Reichhart Jean-Marc, Hoffmann Jules A

Sensing and signaling during infection in Drosophila Article de journal

Dans: Curr. Opin. Immunol., 17 (1), p. 11–17, 2005, ISSN: 0952-7915.

Résumé | Liens | BibTeX | Étiquettes: Animals, Antimicrobial Cationic Peptides, Bacterial Infections, Gene Expression Regulation, Genome, hoffmann, Immunity, Innate, M3i, reichhart, Signal Transduction

Dostert Catherine, Jouanguy Emmanuelle, Irving Phil, Troxler Laurent, Galiana-Arnoux Delphine, Hetru Charles, Hoffmann Jules A, Imler Jean-Luc

The Jak-STAT signaling pathway is required but not sufficient for the antiviral response of drosophila Article de journal

Dans: Nature Immunology, 6 (9), p. 946–953, 2005, ISSN: 1529-2908.

Résumé | Liens | BibTeX | Étiquettes: Animals, bioinformatic, DNA-Binding Proteins, Genetic, Genetically Modified, hoffmann, imler, Insect Viruses, Janus Kinase 1, M3i, Male, Oligonucleotide Array Sequence Analysis, Promoter Regions, Protein-Tyrosine Kinases, Signal Transduction, STAT1 Transcription Factor, Trans-Activators

2004

Bischoff Vincent, Vignal Cécile, Boneca Ivo G, Michel Tatiana, Hoffmann Jules A, Royet Julien

Function of the drosophila pattern-recognition receptor PGRP-SD in the detection of Gram-positive bacteria Article de journal

Dans: Nat. Immunol., 5 (11), p. 1175–1180, 2004, ISSN: 1529-2908.

Résumé | Liens | BibTeX | Étiquettes: Animals, Carrier Proteins, Cell Surface, Gram-Positive Bacteria, Gram-Positive Bacterial Infections, hoffmann, M3i, Mutation, Mycoses, Receptors, Staphylococcus aureus, Toll-Like Receptors

Levy Francine, Rabel David, Charlet Maurice, Bulet Philippe, Hoffmann Jules A, Ehret-Sabatier Laurence

Peptidomic and proteomic analyses of the systemic immune response of Drosophila Article de journal

Dans: Biochimie, 86 (9-10), p. 607–616, 2004, ISSN: 0300-9084.

Résumé | Liens | BibTeX | Étiquettes: Animals, hoffmann, Immunity, M3i, proteomics

Ferrandon Dominique, Imler Jean-Luc, Hoffmann Jules A

Sensing infection in Drosophila: Toll and beyond Article de journal

Dans: Semin Immunol, 16 , p. 43–53, 2004, ISSN: 1044-5323.

Résumé | BibTeX | Étiquettes: Animals, Carrier Proteins/chemistry/immunology/physiology, Cell Surface/immunology/*physiology, Drosophila Proteins/chemistry/immunology/*physiology, Drosophila/genetics/*immunology/microbiology, ferrandon, Fungi/immunology, Gene Expression Regulation, Gram-Negative Bacterial Infections/immunology, Gram-Positive Bacterial Infections/immunology, hoffmann, imler, Immunological, Insect Proteins/chemistry/immunology/physiology, M3i, Models, Non-U.S. Gov't, Receptors, Signal Transduction/immunology/physiology, Support

Imler Jean-Luc, Ferrandon Dominique, Royet Julien, Reichhart Jean-Marc, Hetru Charles, Hoffmann Jules A

Toll-dependent and Toll-independent immune responses in Drosophila Article de journal

Dans: Journal of Endotoxin Research, 10 (4), p. 241–246, 2004, ISSN: 0968-0519.

Résumé | Liens | BibTeX | Étiquettes: Acute-Phase Proteins, Animals, Blood Proteins, Cell Surface, ferrandon, hoffmann, imler, Insect Proteins, M3i, Membrane Glycoproteins, Receptors, reichhart, Toll-Like Receptor 5, Toll-Like Receptors, Up-Regulation

2003

Gobert Vanessa, Gottar Marie, Matskevich Alexey A, Rutschmann Sophie, Royet Julien, Belvin Marcia, Hoffmann Jules A, Ferrandon Dominique

Dual activation of the Drosophila toll pathway by two pattern recognition receptors Article de journal

Dans: Science, 302 (5653), p. 2126–2130, 2003, ISSN: 1095-9203.

Résumé | Liens | BibTeX | Étiquettes: Animals, Carrier Proteins, Cell Surface, DNA Transposable Elements, ferrandon, Gene Expression, Genes, Gram-Negative Bacteria, Gram-Positive Bacteria, Hemolymph, hoffmann, Hypocreales, Insect, Insect Proteins, M3i, Mutation, Phenotype, Receptors, Serine Endopeptidases, Toll-Like Receptors

Thouzeau Cécile, Maho Yvon Le, Froget Guillaume, Sabatier Laurence, Bohec Céline Le, Hoffmann Jules A, Bulet Philippe

Spheniscins, avian beta-defensins in preserved stomach contents of the king penguin, Aptenodytes patagonicus Article de journal

Dans: J. Biol. Chem., 278 (51), p. 51053–51058, 2003, ISSN: 0021-9258.

Résumé | Liens | BibTeX | Étiquettes: Animals, Antimicrobial Cationic Peptides, bacteria, beta-Defensins, Birds, Feeding Behavior, Fungi, Gastrointestinal Contents, hoffmann, M3i, Male, Mass, Matrix-Assisted Laser Desorption-Ionization, Protein Isoforms, Sequence Alignment, Spectrometry

Hoffmann Jules A

The immune response of Drosophila Article de journal

Dans: Nature, 426 (6962), p. 33–38, 2003, ISSN: 1476-4687.

Résumé | Liens | BibTeX | Étiquettes: Animals, Cell Surface, hoffmann, Immunity, Innate, M3i, Membrane Glycoproteins, Receptors, Signal Transduction, Toll-Like Receptor 5, Toll-Like Receptors

Weber Alexander N R, Tauszig-Delamasure Servane, Hoffmann Jules A, Lelièvre Eric, Gascan Hugues, Ray Keith P, Morse Mary A, Imler Jean-Luc, Gay Nicholas J

Binding of the Drosophila cytokine Spätzle to Toll is direct and establishes signaling Article de journal

Dans: Nature Immunology, 4 (8), p. 794–800, 2003, ISSN: 1529-2908.

Résumé | Liens | BibTeX | Étiquettes: Animals, Cell Surface, hoffmann, imler, Insect Proteins, M3i, Protein Binding, Protein Structure, Receptors, Signal Transduction, Tertiary, Toll-Like Receptors

Hetru Charles, Troxler Laurent, Hoffmann Jules A

Drosophila melanogaster antimicrobial defense Article de journal

Dans: J. Infect. Dis., 187 Suppl 2 , p. S327–334, 2003, ISSN: 0022-1899.

Résumé | Liens | BibTeX | Étiquettes: Animal, Animals, Bacterial Infections, bioinformatic, hoffmann, Immunity, Innate, M3i, Mycoses, Parasitic Diseases, Peptides, Signal Transduction

Kurz Léopold C, Chauvet Sophie, Andrès Emmanuel, Aurouze Marianne, Vallet Isabelle, Michel Gérard P F, Uh Mitch, Celli Jean, Filloux Alain, Bentzmann Sophie De, Steinmetz Ivo, Hoffmann Jules A, Finlay Brett B, Gorvel Jean-Pierre, Ferrandon Dominique, Ewbank Jonathan J

Virulence factors of the human opportunistic pathogen Serratia marcescens identified by in vivo screening Article de journal

Dans: Embo J, 22 , p. 1451–60, 2003, ISBN: 0261-4189.

Résumé | Liens | BibTeX | Étiquettes: *Virulence, Animal, Caenorhabditis elegans/*microbiology, ferrandon, hoffmann, M3i, Mutation, Non-U.S. Gov't, Serratia marcescens/genetics/*pathogenicity, Support