@article{volohonsky_plasmodium_2020,
title = {Kinetics of Plasmodium midgut invasion in Anopheles mosquitoes},
author = {Gloria Volohonsky and Perrine Paul-Gilloteaux and Jitka Stafkova and Julien Soichot and Jean Salamero and Elena A. Levashina
},
editor = {Kenneth D. Vernick, Institut Pasteur, FRANCE},
url = {https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1008739},
doi = {10.1371/journal.ppat.1008739},
issn = {1553-7374},
year = {2020},
date = {2020-09-18},
journal = {PLoS Pathog},
volume = {16},
number = {9},
abstract = {The traversal of the mosquito midgut cells is one of the critical stages in the life cycle of malaria parasites. Motile parasite forms, called ookinetes, traverse the midgut epithelium in a dynamic process which is not fully understood. Here, we harnessed transgenic reporters to track invasion of Plasmodium parasites in African and Indian mosquito species. We found important differences in parasite dynam- ics between the two Anopheles species and demonstrated a role of the mosquito comple- ment-like system in regulation of parasite invasion of the midgut cells.},
keywords = {Anopheles, M3i, Malaria, marois, midgut, Plasmodium},
pubstate = {published},
tppubtype = {article}
}
The traversal of the mosquito midgut cells is one of the critical stages in the life cycle of malaria parasites. Motile parasite forms, called ookinetes, traverse the midgut epithelium in a dynamic process which is not fully understood. Here, we harnessed transgenic reporters to track invasion of Plasmodium parasites in African and Indian mosquito species. We found important differences in parasite dynam- ics between the two Anopheles species and demonstrated a role of the mosquito comple- ment-like system in regulation of parasite invasion of the midgut cells.