Dirheimer G, Baranowski W, Keith G
Variations in tRNA modifications, particularly of their queuine content in higher eukaryotes. Its relation to malignancy grading Article de journal
Dans: Biochimie, vol. 77, no. 1-2, p. 99-103, 1995, ISBN: 7599283, (0300-9084 Journal Article Review Review, Tutorial).
Résumé | Liens | BibTeX | Étiquettes: Animals Cell Transformation, Neoplastic/genetics Female Guanine/*analogs & derivatives/analysis Human Neoplasms/*genetics/pathology Ovarian Neoplasms/*genetics/pathology Purines/analysis Pyrimidines/analysis RNA Processing, Non-U.S. Gov't, Post-Transcriptional RNA, Transfer/*chemistry/metabolism Support
@article{,
title = {Variations in tRNA modifications, particularly of their queuine content in higher eukaryotes. Its relation to malignancy grading},
author = {G Dirheimer and W Baranowski and G Keith},
editor = {Editor},
url = {http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=7599283},
isbn = {7599283},
year = {1995},
date = {1995-01-01},
journal = {Biochimie},
volume = {77},
number = {1-2},
pages = {99-103},
abstract = {Literature references dealing with the variations in the modification level of nucleosides in total eukaryotic tRNAs as a function of different physiological status and after drug administration as well as in sequenced cytoplasmic tRNAs between normal and tumor cells and in SV40-transformed cells are reviewed. In addition, special attention is given to guanine replacement of queuine in the first position of the anticodon of tRNAs. A correlation between the level of this undermodification in cancer tissues and the malignancy grading could be found in human ovarian tumors, confirming the results reported in several laboratories for lymphomas and lung cancer tissues. Indeed tRNAs from primary and metastatic human ovarian malignant tumors are Q deficient as compared to tRNAs from normal tissues or benign tumors: thus queuine deficiency increases with malignancy and grading of differentiation.},
note = {0300-9084
Journal Article
Review
Review, Tutorial},
keywords = {Animals Cell Transformation, Neoplastic/genetics Female Guanine/*analogs & derivatives/analysis Human Neoplasms/*genetics/pathology Ovarian Neoplasms/*genetics/pathology Purines/analysis Pyrimidines/analysis RNA Processing, Non-U.S. Gov't, Post-Transcriptional RNA, Transfer/*chemistry/metabolism Support},
pubstate = {published},
tppubtype = {article}
}
Dirheimer G, Baranowski W, Keith G
Variations in tRNA modifications, particularly of their queuine content in higher eukaryotes. Its relation to malignancy grading Article de journal
Dans: Biochimie, vol. 77, no. 1-2, p. 99-103, 1995, ISBN: 7599283, (0300-9084 Journal Article Review Review, Tutorial).
Résumé | Liens | BibTeX | Étiquettes: Animals Cell Transformation, Neoplastic/genetics Female Guanine/*analogs & derivatives/analysis Human Neoplasms/*genetics/pathology Ovarian Neoplasms/*genetics/pathology Purines/analysis Pyrimidines/analysis RNA Processing, Non-U.S. Gov't, Post-Transcriptional RNA, Transfer/*chemistry/metabolism Support
@article{,
title = {Variations in tRNA modifications, particularly of their queuine content in higher eukaryotes. Its relation to malignancy grading},
author = {G Dirheimer and W Baranowski and G Keith},
url = {http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=7599283},
isbn = {7599283},
year = {1995},
date = {1995-01-01},
journal = {Biochimie},
volume = {77},
number = {1-2},
pages = {99-103},
abstract = {Literature references dealing with the variations in the modification level of nucleosides in total eukaryotic tRNAs as a function of different physiological status and after drug administration as well as in sequenced cytoplasmic tRNAs between normal and tumor cells and in SV40-transformed cells are reviewed. In addition, special attention is given to guanine replacement of queuine in the first position of the anticodon of tRNAs. A correlation between the level of this undermodification in cancer tissues and the malignancy grading could be found in human ovarian tumors, confirming the results reported in several laboratories for lymphomas and lung cancer tissues. Indeed tRNAs from primary and metastatic human ovarian malignant tumors are Q deficient as compared to tRNAs from normal tissues or benign tumors: thus queuine deficiency increases with malignancy and grading of differentiation.},
note = {0300-9084
Journal Article
Review
Review, Tutorial},
keywords = {Animals Cell Transformation, Neoplastic/genetics Female Guanine/*analogs & derivatives/analysis Human Neoplasms/*genetics/pathology Ovarian Neoplasms/*genetics/pathology Purines/analysis Pyrimidines/analysis RNA Processing, Non-U.S. Gov't, Post-Transcriptional RNA, Transfer/*chemistry/metabolism Support},
pubstate = {published},
tppubtype = {article}
}
Dirheimer G, Baranowski W, Keith G
Variations in tRNA modifications, particularly of their queuine content in higher eukaryotes. Its relation to malignancy grading Article de journal
Dans: Biochimie, vol. 77, no. 1-2, p. 99-103, 1995, ISBN: 7599283, (0300-9084 Journal Article Review Review, Tutorial).
Résumé | Liens | BibTeX | Étiquettes: Animals Cell Transformation, Neoplastic/genetics Female Guanine/*analogs & derivatives/analysis Human Neoplasms/*genetics/pathology Ovarian Neoplasms/*genetics/pathology Purines/analysis Pyrimidines/analysis RNA Processing, Non-U.S. Gov't, Post-Transcriptional RNA, Transfer/*chemistry/metabolism Support, Unité ARN
@article{,
title = {Variations in tRNA modifications, particularly of their queuine content in higher eukaryotes. Its relation to malignancy grading},
author = {G Dirheimer and W Baranowski and G Keith},
url = {http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=7599283},
isbn = {7599283},
year = {1995},
date = {1995-01-01},
journal = {Biochimie},
volume = {77},
number = {1-2},
pages = {99-103},
abstract = {Literature references dealing with the variations in the modification level of nucleosides in total eukaryotic tRNAs as a function of different physiological status and after drug administration as well as in sequenced cytoplasmic tRNAs between normal and tumor cells and in SV40-transformed cells are reviewed. In addition, special attention is given to guanine replacement of queuine in the first position of the anticodon of tRNAs. A correlation between the level of this undermodification in cancer tissues and the malignancy grading could be found in human ovarian tumors, confirming the results reported in several laboratories for lymphomas and lung cancer tissues. Indeed tRNAs from primary and metastatic human ovarian malignant tumors are Q deficient as compared to tRNAs from normal tissues or benign tumors: thus queuine deficiency increases with malignancy and grading of differentiation.},
note = {0300-9084
Journal Article
Review
Review, Tutorial},
keywords = {Animals Cell Transformation, Neoplastic/genetics Female Guanine/*analogs & derivatives/analysis Human Neoplasms/*genetics/pathology Ovarian Neoplasms/*genetics/pathology Purines/analysis Pyrimidines/analysis RNA Processing, Non-U.S. Gov't, Post-Transcriptional RNA, Transfer/*chemistry/metabolism Support, Unité ARN},
pubstate = {published},
tppubtype = {article}
}