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2000

Sankaranarayanan R, Dock-Bregeon A C, Rees B, Bovee M, Caillet J, Romby P, Francklyn C S, Moras D

Zinc ion mediated amino acid discrimination by threonyl-tRNA synthetase Article de journal

Dans: Nat Struct Biol, vol. 7, no. 6, p. 461-465, 2000, ISBN: 10881191, (1072-8368 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Binding Sites Catalytic Domain Crystallography, Molecular Molecular Sequence Data Protein Binding Protein Conformation Sequence Deletion/genetics Serine-tRNA Ligase/chemistry/metabolism Structure-Activity Relationship Substrate Specificity Support, Non-U.S. Gov't Threonine/analogs & derivatives/chemistry/*metabolism Threonine-tRNA Ligase/*chemistry/genetics/*metabolism Valine-tRNA Ligase/chemistry/metabolism Zinc/*metabolism, ROMBY, Unité ARN, X-Ray Dimerization Escherichia coli/*enzymology Kinetics Models

Kolb F A, Malmgren C, Westhof E, Ehresmann C, Ehresmann B, Wagner E G, Romby P

An unusual structure formed by antisense-target RNA binding involves an extended kissing complex with a four-way junction and a side-by-side helical alignment Article de journal

Dans: RNA, vol. 6, no. 3, p. 311-324, 2000, ISBN: 10744017, (1355-8382 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Antisense/*metabolism RNA, Bacterial Proteins/*metabolism Base Pairing Base Sequence Binding Sites Cations, Divalent Computer Simulation Metals, Double-Stranded/metabolism RNA, Heavy/metabolism Models, Messenger/metabolism RNA, Molecular Molecular Sequence Data *Nucleic Acid Conformation RNA Stability RNA, Non-U.S. Gov't, ROMBY, Spliced Leader/metabolism Support, Unité ARN

Kolb F A, Engdahl H M, Slagter-Jager J G, Ehresmann B, Ehresmann C, Westhof E, Wagner E G, Romby P

Progression of a loop-loop complex to a four-way junction is crucial for the activity of a regulatory antisense RNA Article de journal

Dans: EMBO J, vol. 19, no. 21, p. 5905-5915, 2000, ISBN: 11060041, (0261-4189 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Antisense/*chemistry/*genetics/metabolism RNA, Bacterial Models, Bacterial Proteins/genetics Base Sequence Binding, Bacterial/chemistry/genetics/metabolism Support, Competitive DNA Primers/genetics Escherichia coli/chemistry/genetics/metabolism Genes, Molecular Molecular Sequence Data Mutation Nucleic Acid Conformation RNA, Non-U.S. Gov't, ROMBY, Unité ARN

Dock-Bregeon A, Sankaranarayanan R, Romby P, Caillet J, Springer M, Rees B, Francklyn C S, Ehresmann C, Moras D

Transfer RNA-mediated editing in threonyl-tRNA synthetase. The class II solution to the double discrimination problem Article de journal

Dans: Cell, vol. 103, no. 6, p. 877-884, 2000, ISBN: 11136973, (0092-8674 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Acylation Amino Acid Activation Binding Sites Crystallography, Amino Acyl/chemistry/*metabolism Serine/metabolism Support, Molecular Mutation *Nucleic Acid Conformation Protein Structure, Non-U.S. Gov't Threonine/metabolism Threonine-tRNA Ligase/*chemistry/*genetics/metabolism Zinc/metabolism, ROMBY, Tertiary *RNA Editing RNA, Transfer, Unité ARN, X-Ray Kinetics Models

Brunel C, Romby P

Probing RNA structure and RNA-ligand complexes with chemical probes Article de journal

Dans: Methods Enzymol, vol. 318, p. 3-21, 2000, ISBN: 10889976, (0076-6879 Journal Article Review Review, Tutorial).

Liens | BibTeX | Étiquettes: Crystallography, Genetic, ROMBY, Unité ARN, X-Ray *Ligands Nucleic Acid Conformation Nucleotides/chemistry/metabolism Proteins/chemistry RNA/*chemistry/drug effects/*metabolism Transcription

Benito Y, Kolb F A, Romby P, Lina G, Etienne J, Vandenesch F

Probing the structure of RNAIII, the Staphylococcus aureus agr regulatory RNA, and identification of the RNA domain involved in repression of protein A expression Article de journal

Dans: RNA, vol. 6, no. 5, p. 668-679, 2000, ISBN: 10836788, (1355-8382 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Antisense/*chemistry/genetics/metabolism RNA, Bacterial Models, Bacterial/*chemistry/genetics/metabolism Ribosomes/metabolism Staphylococcal Protein A/*genetics Staphylococcus aureus/*chemistry/*genetics/metabolism Support, Base Sequence Binding Sites/genetics DNA Primers/genetics Escherichia coli/metabolism Gene Expression Genes, Molecular Molecular Sequence Data Nucleic Acid Conformation RNA, Non-U.S. Gov't, ROMBY, Unité ARN

1999

Sankaranarayanan R, Dock-Bregeon A C, Romby P, Caillet J, Springer M, Rees B, Ehresmann C, Ehresmann B, Moras D

The structure of threonyl-tRNA synthetase-tRNA(Thr) complex enlightens its repressor activity and reveals an essential zinc ion in the active site Article de journal

Dans: Cell, vol. 97, no. 3, p. 371-381, 1999, ISBN: 10319817, (0092-8674 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Amino Acid Support, Amino Acyl/*chemistry/genetics/*metabolism Sequence Homology, Messenger/genetics RNA, Non-U.S. Gov't Zinc/*chemistry, ROMBY, Secondary Protein Structure, Tertiary RNA, Transfer, Unité ARN

Perrin L, Romby P, Laurenti P, Berenger H, Kallenbach S, Bourbon H M, Pradel J

The Drosophila modifier of variegation modulo gene product binds specific RNA sequences at the nucleolus and interacts with DNA and chromatin in a phosphorylation-dependent manner Article de journal

Dans: J Biol Chem, vol. 274, no. 10, p. 6315-6323, 1999, ISBN: 10037720, (0021-9258 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Animals Base Sequence Binding Sites/genetics Chromatin/*genetics DNA/*genetics DNA-Binding Proteins/*genetics/metabolism Drosophila/*genetics *Drosophila Proteins *Genes, Insect Insect Proteins/*genetics/metabolism Molecular Sequence Data Phosphorylation RNA/*genetics RNA-Binding Proteins/*genetics/metabolism Support, Non-U.S. Gov't, ROMBY, Unité ARN

1997

Schlegl J, Gegout V, Schlager B, Hentze M W, Westhof E, Ehresmann C, Ehresmann B, Romby P

Probing the structure of the regulatory region of human transferrin receptor messenger RNA and its interaction with iron regulatory protein-1 Article de journal

Dans: RNA, vol. 3, no. 10, p. 1159-1172, 1997, ISBN: 9326491, (1355-8382 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Base Composition Base Sequence Binding Sites Electrophoresis, Messenger/*chemistry/metabolism RNA-Binding Proteins/*metabolism Receptors, Molecular Molecular Sequence Data Mutation *Nucleic Acid Conformation RNA, Non-U.S. Gov't, Polyacrylamide Gel Ethylnitrosourea/pharmacology Human Hydrolysis Hydroxyl Radical/metabolism Iron/metabolism Iron Regulatory Protein 1 Iron-Regulatory Proteins Iron-Sulfur Proteins/*metabolism Lead/pharmacology Models, ROMBY, Transferrin/*genetics Ribonuclease T1/metabolism Support, Unité ARN

Malmgren C, Wagner E G, Ehresmann C, Ehresmann B, Romby P

Antisense RNA control of plasmid R1 replication. The dominant product of the antisense rna-mrna binding is not a full RNA duplex Article de journal

Dans: J Biol Chem, vol. 272, no. 19, p. 12508-12512, 1997, ISBN: 9139701, (0021-9258 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Antisense/*metabolism RNA, Bacterial Proteins/genetics/metabolism Base Sequence Copper/metabolism Electrophoresis, Messenger/*metabolism Ribonuclease III Support, Non-U.S. Gov't, Polyacrylamide Gel Endoribonucleases/metabolism Escherichia coli Lead Molecular Sequence Data Nucleic Acid Conformation Plasmids/*metabolism Pseudomonas RNA, ROMBY, Unité ARN

Eckardt S, Romby P, Sczakiel G

Implications of RNA structure on the annealing of a potent antisense RNA directed against the human immunodeficiency virus type 1 Article de journal

Dans: Biochemistry, vol. 36, no. 42, p. 12711-12721, 1997, ISBN: 9335527, (0006-2960 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Anti-HIV Agents/*chemistry/pharmacology Base Sequence Cells, Antisense/*chemistry/*pharmacology RNA, Calf Thymus Ribonuclease T1 Software Support, Cultured Electrophoresis, Genetic, Insertional Mutagenesis, Non-U.S. Gov't Thermodynamics Transcription, Polyacrylamide Gel HIV-1/*drug effects/genetics Human Kinetics Molecular Sequence Data Mutagenesis, ROMBY, Site-Directed *Nucleic Acid Conformation Oligodeoxyribonucleotides Oligoribonucleotides/*chemistry/pharmacology RNA, Unité ARN, Viral/*chemistry/drug effects Ribonuclease H

1996

Yusupova G, Reinbolt J, Wakao H, Laalami S, Grunberg-Manago M, Romby P, Ehresmann B, Ehresmann C

Topography of the Escherichia coli initiation factor 2/fMet-tRNA(f)(Met) complex as studied by cross-linking Article de journal

Dans: Biochemistry, vol. 35, no. 9, p. 2978-2984, 1996, ISBN: 8608135, (0006-2960 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Amino Acid Sequence Base Sequence Cisplatin/*pharmacology Cross-Linking Reagents Electrophoresis, Met/chemistry/isolation & purification/*metabolism Substrate Specificity Support, Non-U.S. Gov't, Polyacrylamide Gel Escherichia coli/drug effects/*metabolism Eukaryotic Initiation Factor-2/chemistry/isolation & purification/*metabolism Kinetics Molecular Sequence Data Nucleic Acid Conformation Peptide Fragments/chemistry/isolation & purification Protein Conformation RNA, ROMBY, Transfer, Unité ARN

Romby P, Caillet J, Ebel C, Sacerdot C, Graffe M, Eyermann F, Brunel C, Moine H, Ehresmann C, Ehresmann B, Springer M

The expression of E.coli threonyl-tRNA synthetase is regulated at the translational level by symmetrical operator-repressor interactions Article de journal

Dans: EMBO J, vol. 15, no. 21, p. 5976-5987, 1996, ISBN: 8918475, (0261-4189 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Anticodon Base Sequence Binding Sites Binding, Bacterial Gene Expression Regulation, Bacterial/chemistry/genetics/metabolism RNA, Biological Molecular Sequence Data Mutagenesis, Competitive Escherichia coli/*enzymology/*genetics/metabolism Gene Expression Regulation, Enzymologic Models, Genetic, Messenger/genetics/metabolism Repressor Proteins/genetics Support, Non-U.S. Gov't Threonine-tRNA Ligase/*genetics Translation, ROMBY, Site-Directed Nucleic Acid Conformation Operator Regions (Genetics) RNA, Unité ARN

Romby P, Caillet J, Ebel C, Sacerdot C, Graffe M, Eyermann F, Brunel C, Moine H, Ehresmann C, Ehresmann B, Springer M

The expression of E.coli threonyl-tRNA synthetase is regulated at the translational level by symmetrical operator-repressor interactions Article de journal

Dans: EMBO J, vol. 15, no. 21, p. 5976-5987, 1996, ISBN: 8918475, (0261-4189 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Anticodon Base Sequence Binding Sites Binding, Bacterial Gene Expression Regulation, Bacterial/chemistry/genetics/metabolism RNA, Biological Molecular Sequence Data Mutagenesis, Competitive Escherichia coli/*enzymology/*genetics/metabolism Gene Expression Regulation, Enzymologic Models, Genetic, Messenger/genetics/metabolism Repressor Proteins/genetics Support, Non-U.S. Gov't Threonine-tRNA Ligase/*genetics Translation, ROMBY, Site-Directed Nucleic Acid Conformation Operator Regions (Genetics) RNA, Unité ARN

Malmgren C, Engdahl H M, Romby P, Wagner E G

An antisense/target RNA duplex or a strong intramolecular RNA structure 5' of a translation initiation signal blocks ribosome binding: the case of plasmid R1 Article de journal

Dans: RNA, vol. 2, no. 10, p. 1022-1032, 1996, ISBN: 8849778, (1355-8382 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Antisense/chemistry/*metabolism RNA, Bacterial Proteins/genetics Base Sequence Escherichia coli/genetics Genetic Techniques Kinetics Molecular Sequence Data Mutation *Nucleic Acid Conformation Peptide Chain Initiation/*genetics Protein Sorting Signals/genetics *Proteins R Factors/*chemistry/genetics RNA, Bacterial/chemistry/metabolism RNA, Messenger/chemistry/*metabolism Ribosomes/*metabolism Support, Non-U.S. Gov't, ROMBY, Unité ARN

1995

Brunel C, Romby P, Sacerdot C, de Smit M, Graffe M, Dondon J, van Duin J, Ehresmann B, Ehresmann C, Springer M

Stabilised secondary structure at a ribosomal binding site enhances translational repression in E. coli Article de journal

Dans: J Mol Biol, vol. 253, no. 2, p. 277-290, 1995, ISBN: 7563089, (0022-2836 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Bacterial *Gene Expression Regulation, Base Composition Base Sequence Binding Sites Comparative Study Enzyme Repression Escherichia coli/genetics/*metabolism Gene Expression Regulation, Enzymologic Homeostasis Kinetics Mathematics Models, Genetic *Translation, Genetic beta-Galactosidase/biosynthesis, Messenger/biosynthesis/*chemistry/*metabolism Recombinant Proteins/biosynthesis Ribosomes/*metabolism Support, Non-U.S. Gov't Temperature Threonine-tRNA Ligase/*biosynthesis Transcription, ROMBY, Site-Directed *Nucleic Acid Conformation RNA, Theoretical Molecular Sequence Data Mutagenesis, Unité ARN

Zenkova M, Ehresmann C, Caillet J, Springer M, Karpova G, Ehresmann B, Romby P

A novel approach to introduce site-directed specific cross-links within RNA-protein complexes. Application to the Escherichia coli threonyl-tRNA synthetase/translational operator complex Article de journal

Dans: Eur J Biochem, vol. 231, no. 3, p. 726-735, 1995, ISBN: 7544283, (0014-2956 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Alkylation Base Sequence Cross-Linking Reagents Escherichia coli/enzymology/*genetics Molecular Sequence Data Nucleic Acid Conformation *Operator Regions (Genetics) RNA, Bacterial/*chemistry/genetics RNA-Binding Proteins/*chemistry/genetics Support, Genetic, Non-U.S. Gov't Threonine-tRNA Ligase/*genetics *Translation, ROMBY, Unité ARN

1994

Blomberg P, Engdahl H M, Malmgren C, Romby P, Wagner E G

Replication control of plasmid R1: disruption of an inhibitory RNA structure that sequesters the repA ribosome-binding site permits tap-independent RepA synthesis Article de journal

Dans: Mol Microbiol, vol. 12, no. 1, p. 49-60, 1994, ISBN: 7520116, (0950-382x Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Antisense/chemistry/*physiology RNA, Bacterial Models, Bacterial Proteins/genetics/*metabolism Base Sequence Binding Sites *DNA Replication *Gene Expression Regulation, Bacterial/*genetics Reading Frames Ribosomes/*metabolism Sequence Alignment Support, Genetic, Genetic Molecular Sequence Data Mutagenesis Nucleic Acid Conformation Peptides/*genetics/physiology *Proteins R Factors/*genetics RNA, Non-U.S. Gov't Translation, ROMBY, Unité ARN

1993

Mougel M, Allmang C, Eyermann F, Cachia C, Ehresmann B, Ehresmann C

Minimal 16S rRNA binding site and role of conserved nucleotides in Escherichia coli ribosomal protein S8 recognition Article de journal

Dans: Eur J Biochem, vol. 215, no. 3, p. 787-792, 1993, ISBN: 7689052, (0014-2956 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: 16S/*metabolism Ribosomal Proteins/genetics/*metabolism Support, Adenine/metabolism Bacterial Proteins/metabolism Base Composition Base Sequence Binding Sites Conserved Sequence Escherichia coli/*metabolism Molecular Sequence Data Mutation Nucleic Acid Conformation RNA, Bacterial/metabolism RNA, Non-U.S. Gov't, Ribosomal, ROMBY, Unité ARN

Brunel C, Romby P, Moine H, Caillet J, Grunberg-Manago M, Springer M, Ehresmann B, Ehresmann C

Translational regulation of the Escherichia coli threonyl-tRNA synthetase gene: structural and functional importance of the thrS operator domains Article de journal

Dans: Biochimie, vol. 75, no. 12, p. 1167-1179, 1993, ISBN: 8199252, (0300-9084 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Bacterial/*genetics Molecular Sequence Data Mutation Nucleic Acid Conformation *Operator Regions (Genetics) Point Mutation Protein Structure, Base Sequence Escherichia coli/*enzymology/genetics Gene Deletion Gene Expression Regulation, Genetic, Messenger/chemistry/metabolism RNA, Met/chemistry/metabolism Ribosomes/metabolism Structure-Activity Relationship Support, Non-U.S. Gov't Threonine-tRNA Ligase/chemistry/*genetics/metabolism Translation, ROMBY, Secondary RNA, Transfer, Unité ARN

1992

Romby P, Brunel C, Caillet J, Springer M, Grunberg-Manago M, Westhof E, Ehresmann C, Ehresmann B

Molecular mimicry in translational control of E. coli threonyl-tRNA synthetase gene. Competitive inhibition in tRNA aminoacylation and operator-repressor recognition switch using tRNA identity rules Article de journal

Dans: Nucleic Acids Res, vol. 20, no. 21, p. 5633-5640, 1992, ISBN: 1280807, (0305-1048 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Acylation Anticodon Base Sequence Binding, Bacterial Methionine-tRNA Ligase/metabolism Molecular Sequence Data Mutation Nucleic Acid Conformation *Operator Regions (Genetics) RNA, Bacterial/metabolism RNA, Competitive Escherichia coli/enzymology/*genetics *Gene Expression Regulation, Genetic, Met/metabolism RNA, Non-U.S. Gov't Threonine-tRNA Ligase/antagonists & inhibitors/*genetics/metabolism Translation, ROMBY, Thr/metabolism Repressor Proteins/*metabolism Ribosomes/metabolism Support, Transfer, Transfer/*metabolism RNA, Unité ARN

Graffe M, Dondon J, Caillet J, Romby P, Ehresmann C, Ehresmann B, Springer M

The specificity of translational control switched with transfer RNA identity rules Article de journal

Dans: Science, vol. 255, no. 5047, p. 994-996, 1992, ISBN: 1372129, (0036-8075 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Bacterial Genes, Bacterial Molecular Sequence Data Nucleic Acid Conformation RNA, Bacterial Proteins/metabolism Base Sequence DNA Mutational Analysis *Gene Expression Regulation, Bacterial/metabolism RNA, Genetic, Messenger/*metabolism/ultrastructure RNA, Non-U.S. Gov't Threonine-tRNA Ligase/*genetics/metabolism *Translation, ROMBY, Structural, Thr/*metabolism Support, Transfer, Unité ARN

Brunel C, Caillet J, Lesage P, Graffe M, Dondon J, Moine H, Romby P, Ehresmann C, Ehresmann B, Grunberg-Manago M, Springer M

Domains of the Escherichia coli threonyl-tRNA synthetase translational operator and their relation to threonine tRNA isoacceptors Article de journal

Dans: J Mol Biol, vol. 227, no. 3, p. 621-634, 1992, ISBN: 1383551, (0022-2836).

Résumé | Liens | BibTeX | Étiquettes: Bacterial/genetics Gene Expression Regulation, Bacterial/genetics RNA, Base Sequence Escherichia coli/genetics Gene Expression Regulation, Enzymologic/*genetics Molecular Sequence Data Mutagenesis, Genetic/*genetics, Messenger/*genetics/metabolism RNA, Non-U.S. Gov't Threonine-tRNA Ligase/*genetics/metabolism Translation, ROMBY, Site-Directed/genetics Nucleic Acid Conformation RNA, Thr/*genetics/metabolism Recombinant Fusion Proteins/genetics Support, Transfer, Unité ARN

123 Entrées « 3 de 3 »