Publications
2001
Zenkova M, Beloglazova N, Sil'nikov V, Vlassov V, Giege R
RNA cleavage by 1,4-diazabicyclo[2.2.2]octane-imidazole conjugates Article de journal
Dans: Methods Enzymol, vol. 341, p. 468-490, 2001, ISBN: 11582799, (0076-6879 Journal Article).
Liens | BibTeX | Étiquettes: Aza Compounds/*chemistry Base Sequence Bicyclo Compounds/*chemistry Catalysis Comparative Study Imidazoles/*chemistry Kinetics Molecular Sequence Data Nucleic Acid Conformation Oligoribonucleotides/chemistry Phosphorus Radioisotopes RNA/chemistry/*metabolism RNA, Messenger/chemistry Radioisotope Dilution Technique Ribonuclease, Non-U.S. Gov't, Pancreatic/metabolism Support, Unité ARN
@article{,
title = {RNA cleavage by 1,4-diazabicyclo[2.2.2]octane-imidazole conjugates},
author = {M Zenkova and N Beloglazova and V Sil'nikov and V Vlassov and R Giege},
url = {http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11582799},
isbn = {11582799},
year = {2001},
date = {2001-01-01},
journal = {Methods Enzymol},
volume = {341},
pages = {468-490},
note = {0076-6879
Journal Article},
keywords = {Aza Compounds/*chemistry Base Sequence Bicyclo Compounds/*chemistry Catalysis Comparative Study Imidazoles/*chemistry Kinetics Molecular Sequence Data Nucleic Acid Conformation Oligoribonucleotides/chemistry Phosphorus Radioisotopes RNA/chemistry/*metabolism RNA, Messenger/chemistry Radioisotope Dilution Technique Ribonuclease, Non-U.S. Gov't, Pancreatic/metabolism Support, Unité ARN},
pubstate = {published},
tppubtype = {article}
}
1993
Wohrl B M, Ehresmann B, Keith G, Grice S F Le
Nuclease footprinting of human immunodeficiency virus reverse transcriptase/tRNA(Lys-3) complexes Article de journal
Dans: J Biol Chem, vol. 268, no. 18, p. 13617-13624, 1993, ISBN: 7685766, (0021-9258 Journal Article).
Résumé | Liens | BibTeX | Étiquettes: Anticodon Base Sequence HIV-1/*enzymology HIV-1 Reverse Transcriptase Hydrolysis Molecular Sequence Data Nucleic Acid Conformation RNA, Double-Stranded/metabolism RNA, Lys/chemistry/*metabolism RNA-Directed DNA Polymerase/*metabolism Recombinant Proteins/metabolism Ribonuclease, Non-U.S. Gov't Support, P.H.S., Pancreatic/metabolism Support, Transfer, U.S. Gov't, Unité ARN
@article{,
title = {Nuclease footprinting of human immunodeficiency virus reverse transcriptase/tRNA(Lys-3) complexes},
author = {B M Wohrl and B Ehresmann and G Keith and S F Le Grice},
url = {http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=7685766},
isbn = {7685766},
year = {1993},
date = {1993-01-01},
journal = {J Biol Chem},
volume = {268},
number = {18},
pages = {13617-13624},
abstract = {Nuclease footprinting has been used to probe features of binary complexes of type 1 human immunodeficiency virus reverse transcriptase (HIV-1 RT) with both natural and synthetic preparations of its cognate replication primer, tRNA(Lys-3). In addition to heterodimeric RT (p66/p51), ribonucleoprotein complexes containing either the p66 or p51 subunit were analyzed. Footprinting experiments employed both structure- and sequence-specific nucleases. Our results indicate a similar mode of interaction for the three RT preparations tested, suggesting contact with each loop of the tRNA primer (D, anticodon, and T psi C), as well as minor perturbation of the anticodon stem. Although there is little evidence for extensive disruption of the 3'-acceptor stem. RNase A footprinting data with natural and synthetic tRNA suggests that potential base pairing between the T psi C and D loops is disrupted in the presence of RT.},
note = {0021-9258
Journal Article},
keywords = {Anticodon Base Sequence HIV-1/*enzymology HIV-1 Reverse Transcriptase Hydrolysis Molecular Sequence Data Nucleic Acid Conformation RNA, Double-Stranded/metabolism RNA, Lys/chemistry/*metabolism RNA-Directed DNA Polymerase/*metabolism Recombinant Proteins/metabolism Ribonuclease, Non-U.S. Gov't Support, P.H.S., Pancreatic/metabolism Support, Transfer, U.S. Gov't, Unité ARN},
pubstate = {published},
tppubtype = {article}
}