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2009

Kondo J.

[Exploring the "motion" = "function" of the ribosomal A-site molecular switch] Article de journal

Dans: Tanpakushitsu Kakusan Koso, 54 (11), p. 1356-62, 2009, (0039-9450 (Print) 0039-9450 (Linking) Journal Article Review).

BibTeX | Étiquettes: *Binding, *RNA/genetics, Agents/adverse, Anti-Bacterial, Bacteria/drug, Biosynthesis/genetics, Crystallography, Disorders/genetics, effects, effects/pharmacology, Hearing, Humans, Mutation, Protein, Ribosomes/chemistry/*genetics/*physiology, RNA, Sites, Transfer, Untranslated, WESTHOF, X-Ray

Messmer M, Putz J, Suzuki T, Sauter C, Sissler M, Florentz C

Tertiary network in mammalian mitochondrial tRNAAsp revealed by solution probing and phylogeny Article de journal

Dans: Nucleic Acids Res, 37 (20), p. 6881-6895, 2009, ISBN: 19767615, (1362-4962 (Electronic) 0305-1048 (Linking) Journal Article Research Support, Non-U.S. Gov't).

Résumé | Liens | BibTeX | Étiquettes: Asp/*chemistry/*metabolism Transcription, Base Sequence Databases, FLORENTZ, FRUGIER, Genetic, Nucleic Acid Humans Molecular Sequence Data Nucleic Acid Conformation Phylogeny RNA/*chemistry/*metabolism RNA, SISSLER, Transfer, Unité ARN

Messmer M, Gaudry A, Sissler M, Florentz C

Pathology-related mutation A7526G (A9G) helps in the understanding of the 3D structural core of human mitochondrial tRNA(Asp) Article de journal

Dans: RNA, 15 (8), p. 1462-1468, 2009, ISBN: 19535463, (1469-9001 (Electronic) Letter Research Support, Non-U.S. Gov't).

Résumé | Liens | BibTeX | Étiquettes: Asp/*chemistry/*genetics/metabolism Transfer RNA Aminoacylation/genetics, Binding Sites/genetics Humans Kinetics Mitochondrial Myopathies/genetics/metabolism/pathology Models, FLORENTZ, Missense Nucleic Acid Conformation RNA/*chemistry/*genetics/metabolism RNA, Molecular Mutation, SISSLER, Transfer, Unité ARN

Giannouli S, Kyritsis A, Malissovas N, Becker H D, Stathopoulos C

On the role of an unusual tRNAGly isoacceptor in Staphylococcus aureus Article de journal

Dans: Biochimie, 91 (3), p. 344-351, 2009, ISBN: 19014993, (1638-6183 (Electronic) Journal Article Research Support, Non-U.S. Gov't).

Résumé | Liens | BibTeX | Étiquettes: Bacterial Glycine-tRNA Ligase/genetics/*metabolism Peptide Elongation Factor Tu/metabolism RNA, Gly/*genetics/*metabolism Recombinant Proteins/metabolism Sequence Analysis, KERN Anticodon/metabolism Computational Biology/methods Genes, RNA Staphylococcus aureus/*genetics/*metabolism Transfer RNA Aminoacylation/genetics, Transfer, Unité ARN

Frechin M, Senger B, Brayé M, Kern D, Martin R P, Becker H D

Yeast mitochondrial Gln-tRNA(Gln) is generated by a GatFAB-mediated transamidation pathway involving Arc1p-controlled subcellular sorting of cytosolic GluRS Article de journal

Dans: Genes Dev, 23 (9), p. 1119-1130, 2009, ISBN: 19417106, (1549-5477 (Electronic) Journal Article Research Support, Non-U.S. Gov't).

Résumé | Liens | BibTeX | Étiquettes: Amino Acyl/*metabolism RNA-Binding Proteins/*metabolism Saccharomyces cerevisiae/*enzymology/*metabolism Saccharomyces cerevisiae Proteins/*metabolism Transferases/*metabolism, Fungal Glutamate-tRNA Ligase/*metabolism Glutamic Acid/metabolism Mitochondria/*enzymology Protein Binding Protein Transport RNA, KERN Cytoplasm/enzymology Gene Expression Regulation, Transfer, Unité ARN

Bailly M, Blaise M, Lorber B, Thirup S, Kern D

Isolation, crystallization and preliminary X-ray analysis of the transamidosome, a ribonucleoprotein involved in asparagine formation Article de journal

Dans: Acta Crystallogr F Struct Biol Commun, 65 (Pt 6), p. 577-581, 2009, ISBN: 19478435, (1744-3091 (Electronic) Journal Article Research Support, Non-U.S. Gov't).

Résumé | Liens | BibTeX | Étiquettes: Amino Acyl/genetics/metabolism RNA, Asn/*biosynthesis Ribonucleoproteins/*isolation & purification/*metabolism Scattering, KERN FLORENTZ Asparagine/*biosynthesis Aspartate-tRNA Ligase/*chemistry/genetics/*metabolism Crystallization Data Collection Escherichia coli/genetics Light RNA, Radiation Statistics as Topic Thermus thermophilus/genetics/metabolism Transfer RNA Aminoacylation X-Ray Diffraction, Transfer, Unité ARN

2008

Yao P, Zhu B, Jaeger S, Eriani G, Wang E D

Recognition of tRNALeu by Aquifex aeolicus leucyl-tRNA synthetase during the aminoacylation and editing steps Article de journal

Dans: Nucleic Acids Res, 36 (8), p. 2728-2738, 2008, ISBN: 18367476, (1362-4962 (Electronic) Journal Article Research Support, Non-U.S. Gov't).

Résumé | Liens | BibTeX | Étiquettes: Amino Acids/chemistry Anticodon/chemistry Bacteria/enzymology/genetics Base Sequence Iodine Leucine-tRNA Ligase/chemistry/*metabolism Molecular Sequence Data Mutagenesis Nucleic Acid Conformation Protein Footprinting RNA, ERIANI, Leu/*chemistry/genetics/metabolism Ribonucleases Substrate Specificity *Transfer RNA Aminoacylation, Transfer, Unité ARN

Simonetti A, Marzi S, Myasnikov A G, Fabbretti A, Yusupov M, Gualerzi C O, Klaholz B P

Structure of the 30S translation initiation complex Article de journal

Dans: Nature, 455 (7211), p. 416-420, 2008, ISBN: 18758445, (1476-4687 (Electronic) Journal Article Research Support, Non-U.S. Gov't).

Résumé | Liens | BibTeX | Étiquettes: Cryoelectron Microscopy Crystallography, Messenger/chemistry/genetics/metabolism RNA, Met/chemistry/genetics/metabolism/ultrastructure Ribosome Subunits/chemistry/metabolism/ultrastructure Ribosomes/chemistry/*metabolism/*ultrastructure Thermus thermophilus/*enzymology/genetics/*ultrastructure, Molecular Multiprotein Complexes/*chemistry/genetics/metabolism/*ultrastructure *Peptide Chain Initiation, ROMBY, Transfer, Translational Prokaryotic Initiation Factor-1/chemistry/genetics/metabolism/ultrastructure Prokaryotic Initiation Factor-2/chemistry/genetics/metabolism/ultrastructure Protein Conformation RNA, Unité ARN, X-Ray Guanosine Triphosphate/chemistry/metabolism Models

Rederstorff M, Allamand V, Guicheney P, Gartioux C, Richard P, Chaigne D, Krol A, Lescure A

Ex vivo correction of selenoprotein N deficiency in rigid spine muscular dystrophy caused by a mutation in the selenocysteine codon Article de journal

Dans: Nucleic Acids Res, 36 (1), p. 237-244, 2008, ISBN: 18025044, (1362-4962 (Electronic) Journal Article Research Support, Non-U.S. Gov't).

Résumé | Liens | BibTeX | Étiquettes: Amino Acid-Specific/*genetics Selenocysteine/metabolism Selenoproteins/biosynthesis/*deficiency/*genetics Transgenes, KROL Codon/chemistry *Codon, LESCURE, Nonsense Fibroblasts/metabolism Hela Cells Humans Muscle Proteins/biosynthesis/*deficiency/*genetics Muscular Atrophy, Spinal/*genetics/metabolism RNA, Transfer, Unité ARN

Pujol C, Bailly M, Kern D, Marechal-Drouard L, Becker H, Duchene A M

Dual-targeted tRNA-dependent amidotransferase ensures both mitochondrial and chloroplastic Gln-tRNAGln synthesis in plants Article de journal

Dans: Proc Natl Acad Sci U S A, 105 (17), p. 6481-6485, 2008, ISBN: 18441100, (1091-6490 (Electronic) Journal Article Research Support, Non-U.S. Gov't).

Résumé | Liens | BibTeX | Étiquettes: Amino Acyl/*biosynthesis Solanum tuberosum/*enzymology, KERN Arabidopsis/*enzymology Cell Extracts Chloroplasts/*enzymology Cytosol/enzymology Glutamate-tRNA Ligase/metabolism Glutamine/*biosynthesis Mitochondria/*enzymology Nitrogenous Group Transferases/*metabolism Protein Subunits/metabolism Protein Transport RNA, Transfer, Unité ARN

Bonnefond L, Florentz C, Giege R, Rudinger-Thirion J

Decreased aminoacylation in pathology-related mutants of mitochondrial tRNATyr is associated with structural perturbations in tRNA architecture Article de journal

Dans: RNA, 14 (4), p. 641-648, 2008, ISBN: 18268021, (1469-9001 (Electronic) In Vitro Journal Article Research Support, Non-U.S. Gov't).

Résumé | Liens | BibTeX | Étiquettes: Base Sequence Humans Mitochondrial Diseases/genetics/metabolism Models, FLORENTZ, FRUGIER, Molecular Molecular Sequence Data Nucleic Acid Conformation *Point Mutation RNA/*chemistry/*genetics/metabolism RNA Stability RNA, Transfer, Tyr/*chemistry/*genetics/metabolism *Transfer RNA Aminoacylation, Unité ARN

Blaise M, Olieric V, Sauter C, Lorber B, Roy B, Karmakar S, Banerjee R, Becker H D, Kern D

Crystal structure of glutamyl-queuosine tRNAAsp synthetase complexed with L-glutamate: structural elements mediating tRNA-independent activation of glutamate and glutamylation of tRNAAsp anticodon Article de journal

Dans: J Mol Biol, 381 (5), p. 1224-1237, 2008, ISBN: 18602926, (1089-8638 (Electronic) Journal Article Research Support, Non-U.S. Gov't).

Résumé | Liens | BibTeX | Étiquettes: Adenosine Triphosphate/metabolism Amino Acid Sequence Amino Acyl-tRNA Synthetases/*chemistry Anticodon/*metabolism Base Sequence Binding Sites Catalysis Conserved Sequence Crystallography, Asp/*chemistry/genetics Regulatory Sequences, FFRUGIER, Molecular Molecular Sequence Data Nucleic Acid Conformation Nucleoside Q/*chemistry Protein Structure, Ribonucleic Acid/*genetics Thermus thermophilus/enzymology, Secondary RNA, Transfer, Unité ARN, X-Ray Escherichia coli/*enzymology Escherichia coli Proteins/*chemistry Glutamic Acid/*chemistry Models

2007

Roy H, Becker H D, Mazauric M H, Kern D

Structural elements defining elongation factor Tu mediated suppression of codon ambiguity Article de journal

Dans: Nucleic Acids Res, 35 (10), p. 3420-3430, 2007, ISBN: 17478519, (1362-4962 (Electronic) Journal Article Research Support, Non-U.S. Gov't).

Résumé | Liens | BibTeX | Étiquettes: Amino Acyl/*chemistry/metabolism RNA, Asn/*chemistry/metabolism RNA, Asp/chemistry/metabolism Thermus thermophilus/genetics *Transfer RNA Aminoacylation, KERN Base Pairing *Codon Escherichia coli Proteins/metabolism Models, Molecular Peptide Elongation Factor Tu/*chemistry/metabolism Protein Binding RNA, Transfer, Unité ARN

Henriet S, Sinck L, Bec G, Gorelick R J, Marquet R, Paillart J C

Vif is a RNA chaperone that could temporally regulate RNA dimerization and the early steps of HIV-1 reverse transcription Article de journal

Dans: Nucleic Acids Res, 35 (15), p. 5141-5153, 2007, ISBN: 17660191, (1362-4962 (Electronic) Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't).

Résumé | Liens | BibTeX | Étiquettes: Amino Acyl/metabolism RNA, Capsid Proteins/metabolism DNA, gag/metabolism Gene Products, Human Immunodeficiency Virus, Human Immunodeficiency Virus vif Gene Products, MARQUET, PAILLART, Single-Stranded/biosynthesis Dimerization Gene Products, Transfer, Unité ARN, vif/*metabolism HIV-1/*genetics Molecular Chaperones/*metabolism RNA, Viral/*metabolism *Reverse Transcription Viral Proteins/metabolism gag Gene Products

Maone E, Stefano M Di, Berardi A, Benelli D, Marzi S, Teana A La, Londei P

Functional analysis of the translation factor aIF2/5B in the thermophilic archaeon Sulfolobus solfataricus Article de journal

Dans: Mol Microbiol, 65 (3), p. 700-13, 2007, ISBN: 17608795, (0950-382X (Print) 0950-382X (Linking) Journal Article Research Support, Non-U.S. Gov't).

Résumé | Liens | BibTeX | Étiquettes: Archaeal Hydrolysis Peptide Chain Initiation, Met/metabolism Recombinant Fusion Proteins/metabolism Ribosomes/metabolism Sulfolobus solfataricus/genetics/*metabolism, Molecular Conserved Sequence GTP Phosphohydrolases/metabolism Gene Expression Genes, ROMBY, Secondary RNA, Transfer, Translational Peptide Initiation Factors/chemistry/isolation & purification/*metabolism Protein Binding *Protein Biosynthesis Protein Structure, Unité ARN

2006

Westhof E

The ribosomal decoding site and antibiotics Article de journal

Dans: Biochimie, 88 (8), p. 931-933, 2006, ISBN: 16876930, (0300-9084 (Print) Editorial).

Liens | BibTeX | Étiquettes: Anti-Bacterial Agents/metabolism/*pharmacology Bacteria/*drug effects/genetics/growth & development Binding Sites/drug effects Protein Biosynthesis/drug effects/genetics RNA Amino Acyl/*metabolism, Bacterial/*metabolism RNA, Transfer, Unité ARN, WESTHOF

Fender A, Sauter C, Messmer M, Putz J, Giege R, Florentz C, Sissler M

Loss of a primordial identity element for a mammalian mitochondrial aminoacylation system Article de journal

Dans: J Biol Chem, 281 (23), p. 15980-15986, 2006, ISBN: 16597625, (0021-9258 (Print) Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Acylation Base Sequence Humans Kinetics Mutagenesis Nucleic Acid Conformation Plasmids RNA | Non-U.S. Gov't, Asp/chemistry/genetics/*metabolism Research Support, FLORENTZ, FRUGIER, Non-U.S. Gov't, SISSLER, Transfer, Unité ARN

2005

Jenner L, Romby P, Rees B, Schulze-Briese C, Springer M, Ehresmann C, Ehresmann B, Moras D, Yusupova G, Yusupov M

Translational operator of mRNA on the ribosome: how repressor proteins exclude ribosome binding Article de journal

Dans: Science, 308 (5718), p. 120-123, 2005, ISBN: 15802605, (1095-9203 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: 16S/chemistry/metabolism RNA, Bacterial/*chemistry/metabolism RNA, Messenger/*chemistry/metabolism RNA, Met/chemistry/metabolism *Regulatory Sequences, Molecular Nucleic Acid Conformation *Protein Biosynthesis RNA, Non-U.S. Gov't Ribosomal Proteins/metabolism Ribosomes/*metabolism Thermus thermophilus/genetics/*metabolism Threonine-tRNA Ligase/genetics/metabolism, Ribonucleic Acid Repressor Proteins/*metabolism Research Support, Ribosomal, ROMBY, ROMBY Bacterial Proteins/metabolism Base Pairing Binding Sites Crystallization Crystallography, Transfer, Unité ARN, X-Ray Fourier Analysis Models

Graindorge J S, Senger B, Tritch D, Simos G, Fasiolo F

Role of Arc1p in the modulation of yeast glutamyl-tRNA synthetase activity Article de journal

Dans: Biochemistry, 44 (4), p. 1344-1352, 2005, ISBN: 15667228, (0006-2960 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: FASIOLO Adenosine Triphosphate/chemistry/metabolism Amino Acid Sequence Aminoacylation Base Sequence Diphosphates/chemistry/metabolism Enzyme Activation Gene Expression Regulation, Fungal Glutamate-tRNA Ligase/isolation & purification/*metabolism Kinetics Molecular Sequence Data Peptide Fragments/chemistry/metabolism Protein Binding Protein Structure, Fungal/genetics/metabolism RNA, Genetic, Glu/genetics/metabolism RNA-Binding Proteins/*chemistry/isolation & purification/metabolism Research Support, Non-U.S. Gov't Saccharomyces cerevisiae/enzymology/genetics/metabolism Saccharomyces cerevisiae Proteins/*chemistry/isolation & purification/metabolism Transcription, Tertiary RNA, Transfer, Unité ARN

Bonnefond L, Frugier M, Giege R, Rudinger-Thirion J

Human mitochondrial TyrRS disobeys the tyrosine identity rules Article de journal

Dans: RNA, 11 (5), p. 558-562, 2005, ISBN: 15840810, (1355-8382 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Amino Acid Sequence Base Sequence Catalytic Domain Humans Mitochondria/*enzymology Molecular Sequence Data RNA, FRUGIER, Non-U.S. Gov't Substrate Specificity Tyrosine/genetics/*metabolism Tyrosine-tRNA Ligase/chemistry/*metabolism, Transfer, Tyr/genetics/*metabolism Research Support, Unité ARN

2004

Costa A., de Barros J. P. Pais, Keith G., Baranowski W., Desgres J.

Determination of queuosine derivatives by reverse-phase liquid chromatography for the hypomodification study of Q-bearing tRNAs from various mammal liver cells Article de journal

Dans: J Chromatogr B Analyt Technol Biomed Life Sci, 801 (2), p. 237-47, 2004, (1570-0232 Journal Article).

Résumé | BibTeX | Étiquettes: *Chromatography, &, Acyl/chemistry, Amino, Animals, Asn/chemistry, Cells, Chickens, Cultured, derivatives/*analysis, Experimental, Gov't, Hepatocytes/chemistry, high, KEITH, liquid, Liver, Liver/*chemistry, Neoplasms, Non-U.S., Nucleoside, Pressure, purification, Q/*analogs, Rats, RNA, Support, Transfer, Transfer/*chemistry/isolation, tumor

Martineau Y., Bec C. Le, Monbrun L., Allo V., Chiu I. M., Danos O., Moine H., Prats H., Prats A. C.

Internal ribosome entry site structural motifs conserved among mammalian fibroblast growth factor 1 alternatively spliced mRNAs Article de journal

Dans: Mol Cell Biol, 24 (17), p. 7622-35, 2004, (0270-7306 Journal Article).

Résumé | BibTeX | Étiquettes: (Genetics), *5', *Alternative, *Nucleic, *Promoter, 1/*genetics, Acid, Alignment, Animals, Base, Cell, Conformation, Data, EHRESMANN, Factor, Fibroblast, Gene, Genes, Genetic, Gov't, Growth, Human, Line, Messenger/chemistry/*genetics/metabolism, Mice, Molecular, Muscle, Mutagenesis, Non-U.S., Regions, Ribosomes/*metabolism, RNA, Sequence, Site-Directed, Skeletal/cytology/physiology, Splicing, Structural/genetics, Support, Techniques, Transfer, Untranslated, Vectors

Zheng Y G, Wei H, Ling C, Martin F, Eriani G, Wang E D

Two distinct domains of the beta subunit of Aquifex aeolicus leucyl-tRNA synthetase are involved in tRNA binding as revealed by a three-hybrid selection Article de journal

Dans: Nucleic Acids Res, 32 (11), p. 3294-3303, 2004, ISBN: 15208367, (1362-4962 Evaluation Studies Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Amino Acid Sequence Binding Sites Gram-Negative Bacteria/*enzymology Kinetics Leucine-tRNA Ligase/*chemistry/genetics/*metabolism Molecular Sequence Data Mutation Protein Structure, ERIANI, Leu/*metabolism Saccharomyces cerevisiae/genetics *Two-Hybrid System Techniques, Tertiary Protein Subunits/chemistry RNA, Transfer, Unité ARN

Théobald-Dietrich A, Frugier M, Giege R, Rudinger-Thirion J

Atypical archaeal tRNA pyrrolysine transcript behaves towards EF-Tu as a typical elongator tRNA Article de journal

Dans: Nucleic Acids Res, 32 (3), p. 1091-1096, 2004, ISBN: 14872064, (1362-4962 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Anticodon/metabolism Base Sequence Lysine/*analogs & derivatives/*metabolism Lysine-tRNA Ligase/metabolism Methanosarcina barkeri/genetics Mitochondria/genetics Molecular Sequence Data Nucleic Acid Conformation Peptide Elongation Factor Tu/*metabolism RNA, Archaeal/chemistry/*metabolism RNA, FRUGIER, Non-U.S. Gov't Yeasts/enzymology, Ser/chemistry Selenocysteine/metabolism Support, Transfer, Transfer/chemistry/*metabolism RNA, Unité ARN

Sohm B, Sissler M, Park H, King M P, Florentz C

Recognition of human mitochondrial tRNALeu(UUR) by its cognate leucyl-tRNA synthetase Article de journal

Dans: J Mol Biol, 339 (1), p. 17-29, 2004, ISBN: 15123417, (0022-2836 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Cultured, FLORENTZ, FLORENTZ *Acylation Base Sequence Comparative Study Human Kinetics Leucine/metabolism Leucine-tRNA Ligase/genetics/*metabolism Mitochondria/*metabolism Molecular Sequence Data Mutation Nucleic Acid Conformation Osteosarcoma/metabolism RNA/*genetics/metabolism RNA, Genetic/*genetics Tumor Cells, Leu/genetics/*metabolism Solutions Substrate Specificity Support, Non-U.S. Gov't Support, P.H.S. Transcription, SISSLER, Transfer, U.S. Gov't, Unité ARN

Sissler M, Helm M, Frugier M, Giege R, Florentz C

Aminoacylation properties of pathology-related human mitochondrial tRNA(Lys) variants Article de journal

Dans: RNA, 10 (5), p. 841-853, 2004, ISBN: 15100439, (1355-8382 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: ERIANI, FLORENTZ, FLORENTZ GIEGE Acylation Aminoacyltransferases/*genetics Human MERRF Syndrome/genetics Mitochondria/*genetics Mitochondrial Diseases/*genetics Mutation Nucleic Acid Conformation RNA, FRUGIER, Lys/*genetics Sequence Analysis, Non-U.S. Gov't Variation (Genetics), RNA Support, SISSLER, Transfer, Unité ARN

Rangan P, Masquida B, Westhof E, Woodson S A

Architecture and folding mechanism of the Azoarcus Group I Pre-tRNA Article de journal

Dans: J Mol Biol, 339 (1), p. 41-51, 2004, ISBN: 15123419, (0022-2836 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Azoarcus/enzymology/*genetics Base Sequence Binding Sites Exoribonucleases/metabolism Hydroxyl Radical/metabolism Introns/*genetics Magnesium/chemistry Models, Bacterial/*chemistry/genetics/*metabolism RNA, Ile/chemistry/*genetics Substrate Specificity Support, Molecular Molecular Sequence Data *Nucleic Acid Conformation RNA Precursors/*genetics RNA Splice Sites/genetics RNA Splicing RNA, Non-U.S. Gov't Support, P.H.S., Transfer, U.S. Gov't, Unité ARN, WESTHOF

Martin F, Barends S, Eriani G

Single amino acid changes in AspRS reveal alternative routes for expanding its tRNA repertoire in vivo Article de journal

Dans: Nucleic Acids Res, 32 (13), p. 4081-4089, 2004, ISBN: 15289581, (1362-4962 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Amino Acid Substitution Anticodon/metabolism Aspartate-tRNA Ligase/*chemistry/genetics/*metabolism Aspartic Acid/metabolism Binding Sites Models, Amino Acyl/chemistry/*metabolism Support, ERIANI, Molecular Mutation Phenotype Protein Engineering Protein Structure, Non-U.S. Gov't, Tertiary RNA, Transfer, Unité ARN

Levinger L, Oestreich I, Florentz C, Morl M

A pathogenesis-associated mutation in human mitochondrial tRNALeu(UUR) leads to reduced 3'-end processing and CCA addition Article de journal

Dans: J Mol Biol, 337 (3), p. 535-544, 2004, ISBN: 15019775, (0022-2836 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: FLORENTZ, FLORENTZ Human Kinetics Mitochondrial Diseases/*genetics Nucleic Acid Conformation *Point Mutation RNA/*genetics/physiology *RNA 3' End Processing RNA Nucleotidyltransferases/metabolism RNA, Leu/*genetics/physiology Support, Non-U.S. Gov't Support, P.H.S., Transfer, U.S. Gov't, Unité ARN

Fender A, Sissler M, Florentz C, Giege R

Functional idiosyncrasies of tRNA isoacceptors in cognate and noncognate aminoacylation systems Article de journal

Dans: Biochimie, 86 (1), p. 21-29, 2004, ISBN: 14987797, (0300-9084 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Amino Acyl/genetics/*metabolism Saccharomyces cerevisiae Substrate Specificity/genetics/physiology Support, Chemical Molecular Sequence Data Mutation Nucleic Acid Conformation Protein Binding/physiology RNA, FLORENTZ, GIEGE FLORENTZ Amino Acid Activation/physiology Amino Acyl-tRNA Ligases/*metabolism Anticodon Bacterial Proteins/metabolism Base Sequence Cloning, Molecular Computer Simulation Escherichia coli Models, Non-U.S. Gov't Thermus thermophilus, SISSLER, Transfer, Transfer/genetics/*metabolism RNA, Unité ARN

Fender A, Geslain R, Eriani G, Giege R, Sissler M, Florentz C

A yeast arginine specific tRNA is a remnant aspartate acceptor Article de journal

Dans: Nucleic Acids Res, 32 (17), p. 5076-5086, 2004, ISBN: 15452274, (1362-4962 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Arg/*chemistry/genetics/metabolism RNA, Asp/*chemistry/genetics/metabolism Saccharomyces cerevisiae/*genetics Sequence Alignment Support, ERIANI, ERIANI FLORENTZ GIEGE Aspartic Acid/metabolism Base Sequence *Evolution, FLORENTZ, Fungal/*chemistry/genetics/metabolism RNA, Molecular Molecular Sequence Data Point Mutation RNA, Non-U.S. Gov't, SISSLER, Transfer, Unité ARN

Dubois D Y, Blaise M, Becker H D, Campanacci V, Keith G, Giege R, Cambillau C, Lapointe J, Kern D

An aminoacyl-tRNA synthetase-like protein encoded by the Escherichia coli yadB gene glutamylates specifically tRNAAsp Article de journal

Dans: Proc Natl Acad Sci U S A, 101 (20), p. 7530-7535, 2004, ISBN: 15096594, (0027-8424 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Asp/*metabolism Support, KERN GIEGE Amino Acyl-tRNA Ligases/chemistry/genetics/*metabolism Crystallography, Messenger/metabolism RNA, Non-U.S. Gov't, Tertiary RNA, Transfer, Unité ARN, X-Ray Escherichia coli/enzymology/genetics/*metabolism Escherichia coli Proteins/chemistry/genetics/*metabolism Glutamic Acid/*metabolism Peptide Elongation Factor 2/metabolism Phylogeny Protein Structure

Costa A, de Barros J P Pais, Keith G, Baranowski W, Desgres J

Determination of queuosine derivatives by reverse-phase liquid chromatography for the hypomodification study of Q-bearing tRNAs from various mammal liver cells Article de journal

Dans: J Chromatogr B Analyt Technol Biomed Life Sci, 801 (2), p. 237-247, 2004, ISBN: 14751792, (1570-0232 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Amino Acyl/chemistry RNA, Asn/chemistry Rats Support, Cultured, Cultured Chickens *Chromatography, Experimental Nucleoside Q/*analogs & derivatives/*analysis RNA, High Pressure Liquid Hepatocytes/chemistry Liver/*chemistry Liver Neoplasms, KEITH Animals Cells, Non-U.S. Gov't Tumor Cells, Transfer, Transfer/*chemistry/isolation & purification RNA, Unité ARN

Campanacci V, Dubois D Y, Becker H D, Kern D, Spinelli S, Valencia C, Pagot F, Salomoni A, Grisel S, Vincentelli R, Bignon C, Lapointe J, Giege R, Cambillau C

The Escherichia coli YadB gene product reveals a novel aminoacyl-tRNA synthetase like activity Article de journal

Dans: J Mol Biol, 337 (2), p. 273-283, 2004, ISBN: 15003446, (0022-2836 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Amino Acid Support, Bacterial Glutamate-tRNA Ligase/chemistry/genetics/metabolism Glutamic Acid/metabolism Kinetics Ligands Models, Glu/metabolism Sequence Homology, KERN GIEGE Adenosine Monophosphate/metabolism Adenosine Triphosphate/metabolism Amino Acid Sequence Amino Acyl-tRNA Ligases/chemistry/*genetics/*metabolism Carrier Proteins/metabolism Crystallography, Molecular Molecular Sequence Data Neoplasm Proteins/metabolism Nuclear Proteins/metabolism Protein Conformation RNA, Non-U.S. Gov't Thermus thermophilus/enzymology/genetics Zinc/metabolism, Transfer, Unité ARN, X-Ray Escherichia coli/*enzymology/*genetics Escherichia coli Proteins/chemistry/*genetics/*metabolism Genes

Blaise M, Becker H D, Keith G, Cambillau C, Lapointe J, Giege R, Kern D

A minimalist glutamyl-tRNA synthetase dedicated to aminoacylation of the tRNAAsp QUC anticodon Article de journal

Dans: Nucleic Acids Res, 32 (9), p. 2768-2775, 2004, ISBN: 15150343, (1362-4962 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Asp/chemistry/genetics/*metabolism RNA, Bacterial/chemistry/genetics/metabolism RNA, Glu/chemistry/genetics/metabolism Support, KERN Acylation Anticodon/chemistry/genetics/*metabolism Base Sequence Conserved Sequence Escherichia coli/*enzymology/*genetics Evolution Glutamate-tRNA Ligase/*chemistry/genetics/*metabolism Molecular Mimicry Nucleoside Q/genetics/*metabolism Periodic Acid/pharmacology RNA, Non-U.S. Gov't, Transfer, Unité ARN

Ador L, Jaeger S, Geslain R, Martin F, Cavarelli J, Eriani G

Mutation and evolution of the magnesium-binding site of a class II aminoacyl-tRNA synthetase Article de journal

Dans: Biochemistry, 43 (22), p. 7028-7037, 2004, ISBN: 15170340, (0006-2960 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Acylation Adenosine Triphosphate/metabolism Amino Acid Substitution Aspartate-tRNA Ligase/chemistry/genetics/*metabolism Aspartic Acid/metabolism Binding Sites Catalytic Domain Cell Death Combinatorial Chemistry Techniques Comparative Study *Evolution, Asp/metabolism Saccharomyces cerevisiae/*enzymology Support, ERIANI, Molecular Kinetics Magnesium/*metabolism Mutagenesis, Non-U.S. Gov't Transfection, Site-Directed Mutation/*genetics Peptide Library Protein Binding Protein Conformation RNA, Transfer, Unité ARN

2003

Zhao M W, Hao R, Chen J F, Martin F, Eriani G, Wang E D

Enzymes assembled from Aquifex aeolicus and Escherichia coli leucyl-tRNA synthetases Article de journal

Dans: Biochemistry, 42 (25), p. 7694-7700, 2003, ISBN: 12820878, (0006-2960 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Amino Acyl-tRNA Ligases/genetics/*metabolism Escherichia coli/*enzymology Evolution, ERIANI, Horizontal Heat Kinetics Mutation RNA, Leu/*metabolism Structure-Activity Relationship Support, Molecular Gene Transfer, Non-U.S. Gov't, Transfer, Unité ARN

Sohm B, Frugier M, Brule H, Olszak K, Przykorska A, Florentz C

Towards understanding human mitochondrial leucine aminoacylation identity Article de journal

Dans: J Mol Biol, 328 (5), p. 995-1010, 2003, ISBN: 12729737, (0022-2836 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Base Sequence Human In Vitro Leucine/*metabolism Leucine-tRNA Ligase/*metabolism Mitochondria/*metabolism Mitochondrial Diseases/genetics/metabolism Molecular Sequence Data Mutation Nucleic Acid Conformation RNA, ERIANI, FLORENTZ, FRUGIER, Leu/chemistry/genetics/*metabolism Recombinant Proteins/genetics/metabolism Solutions Substrate Specificity Support, Non-U.S. Gov't Variation (Genetics), Transfer, Unité ARN

Ryckelynck M, Giege R, Frugier M

Yeast tRNA(Asp) charging accuracy is threatened by the N-terminal extension of aspartyl-tRNA synthetase Article de journal

Dans: J Biol Chem, 278 (11), p. 9683-9690, 2003, ISBN: 12486031, (0021-9258 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Amino Acid Motifs Aspartate-tRNA Ligase/*metabolism Aspartic Acid/chemistry Base Sequence Codon Escherichia coli/metabolism Kinetics Molecular Sequence Data Nucleic Acid Conformation Nucleic Acids/chemistry Protein Structure, Asp/*chemistry Support, FRUGIER, Messenger/metabolism RNA, Non-U.S. Gov't Yeasts/metabolism, Secondary Protein Structure, Tertiary RNA, Transfer, Unité ARN

Romby P, Springer M

Bacterial translational control at atomic resolution Article de journal

Dans: Trends Genet, 19 (3), p. 155-161, 2003, ISBN: 12615010, (0168-9525 Journal Article Review Review, Tutorial).

Résumé | Liens | BibTeX | Étiquettes: Bacterial *Gene Expression Regulation, Bacterial Models, Base Sequence Conserved Sequence Escherichia coli/*enzymology/*genetics *Gene Expression Regulation, Biological Models, Enzymologic Genes, Genetic, Messenger/genetics/*metabolism RNA, Molecular Molecular Mimicry Nucleic Acid Conformation Operator Regions (Genetics) RNA, Non-U.S. Gov't Threonine-tRNA Ligase/chemistry/*genetics/metabolism *Translation, ROMBY, Thr/*metabolism RNA-Binding Proteins/metabolism Support, Transfer, Unité ARN

Rigourd M, Goldschmidt V, Brule F, Morrow C D, Ehresmann B, Ehresmann C, Marquet R

Structure-function relationships of the initiation complex of HIV-1 reverse transcription: the case of mutant viruses using tRNA(His) as primer Article de journal

Dans: Nucleic Acids Res, 31 (19), p. 5764-5775, 2003, ISBN: 14500840, (1362-4962 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Base Sequence Comparative Study DNA, Genetic, Genetic *Transcription Initiation Site *Transcription, His/*metabolism RNA, MARQUET, Non-U.S. Gov't Templates, Post-Transcriptional RNA, Transfer, Unité ARN, Viral HIV-1/*genetics/metabolism HIV-1 Reverse Transcriptase/metabolism Kinetics Macromolecular Systems Molecular Sequence Data Mutation RNA Probes RNA Processing, Viral/*biosynthesis/genetics Sequence Alignment Structure-Activity Relationship Support, Viral/biosynthesis *Gene Expression Regulation

Rigourd M, Bec G, Benas P, Grice S F Le, Ehresmann B, Ehresmann C, Marquet R

Effects of tRNA 3 Lys aminoacylation on the initiation of HIV-1 reverse transcription Article de journal

Dans: Biochimie, 85 (5), p. 521-525, 2003, ISBN: 12763311, (0300-9084 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Acetyltransferases/metabolism *Acylation Animals Cattle HIV-1/*physiology HIV-1 Reverse Transcriptase/pharmacology RNA/genetics RNA, Genetic/drug effects/*physiology Virus Assembly, Lys/*chemistry/drug effects Support, MARQUET, Non-U.S. Gov't Transcription, Transfer, Unité ARN

Levinger L, Giege R, Florentz C

Pathology-related substitutions in human mitochondrial tRNA(Ile) reduce precursor 3' end processing efficiency in vitro Article de journal

Dans: Nucleic Acids Res, 31 (7), p. 1904-1912, 2003, ISBN: 12655007, (1362-4962 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Base Sequence DNA, FLORENTZ, Ile/*genetics/metabolism Support, Mitochondrial/*genetics Endoribonucleases/metabolism Hela Cells Human Kinetics Molecular Sequence Data Mutation RNA Precursors/genetics/metabolism *RNA Processing, Non-U.S. Gov't Support, P.H.S., Post-Transcriptional RNA, Transfer, U.S. Gov't, Unité ARN

Goldschmidt V, Ehresmann C, Ehresmann B, Marquet R

Does the HIV-1 primer activation signal interact with tRNA3(Lys) during the initiation of reverse transcription? Article de journal

Dans: Nucleic Acids Res, 31 (3), p. 850-859, 2003, ISBN: 12560480, (1362-4962 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Amino Acyl/chemistry/*metabolism RNA, Base Sequence Binding Sites DNA Primers DNA, Genetic, MARQUET, Non-U.S. Gov't *Transcription, Transfer, Unité ARN, Viral HIV-1/*genetics HIV-1 Reverse Transcriptase/*metabolism Kinetics Molecular Sequence Data Mutation Nucleic Acid Conformation Oligoribonucleotides RNA, Viral/biosynthesis *Gene Expression Regulation, Viral/chemistry/genetics/metabolism Support

Giege R

Genetic code expansion Article de journal

Dans: Nat Struct Biol, 10 (6), p. 414-416, 2003, ISBN: 12768199, (1072-8368 Comment News).

Liens | BibTeX | Étiquettes: Amino Acyl-tRNA Ligases/*chemistry/genetics/*metabolism Codon *Genetic Code Genetic Engineering/methods Human RNA, Transfer, Transfer/*chemistry/*metabolism RNA, Tyr/chemistry/metabolism Structure-Activity Relationship Tyrosine/chemistry/*genetics/metabolism, Unité ARN

Geslain R, Martin F, Camasses A, Eriani G

A yeast knockout strain to discriminate between active and inactive tRNA molecules Article de journal

Dans: Nucleic Acids Res, 31 (16), p. 4729-4737,