@article{,
title = {Spatial and temporal expression patterns of selenoprotein genes during embryogenesis in zebrafish},
author = {C Thisse and A Degrave and G V Kryukov and V N Gladyshev and S Obrecht-Pflumio and A Krol and B Thisse and A Lescure},
url = {http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=12915322},
isbn = {12915322},
year = {2003},
date = {2003-01-01},
journal = {Gene Expr Patterns},
volume = {3},
number = {4},
pages = {525-532},
abstract = {Selenium is important for embryogenesis in vertebrates but little is known about the expression patterns and biological functions of most selenoprotein genes. Taking advantage of the zebrafish model, systematic analysis of selenoprotein gene expression was performed by in situ hybridization on whole-mount embryos at different developmental stages. Twenty-one selenoprotein mRNAs were analyzed and all of them exhibited expression patterns restricted to specific tissues. Moreover, we demonstrated that highly similar selenoprotein paralogs were expressed within distinct territories. Therefore, tissue- and development-specific expression patterns provided new information for selenoproteins of unknown function.},
note = {1567-133x
Journal Article},
keywords = {Animals Gene Expression Regulation, Developmental In Situ Hybridization Molecular Sequence Data Proteins/*genetics/metabolism RNA Probes RNA, LESCURE, Messenger/metabolism Support, Non-U.S. Gov't Support, P.H.S. Tissue Distribution Zebrafish/*embryology, U.S. Gov't, Unité ARN},
pubstate = {published},
tppubtype = {article}
}
Selenium is important for embryogenesis in vertebrates but little is known about the expression patterns and biological functions of most selenoprotein genes. Taking advantage of the zebrafish model, systematic analysis of selenoprotein gene expression was performed by in situ hybridization on whole-mount embryos at different developmental stages. Twenty-one selenoprotein mRNAs were analyzed and all of them exhibited expression patterns restricted to specific tissues. Moreover, we demonstrated that highly similar selenoprotein paralogs were expressed within distinct territories. Therefore, tissue- and development-specific expression patterns provided new information for selenoproteins of unknown function.