@article{pantarotto_functionalized_2004,
title = {Functionalized Carbon Nanotubes for Plasmid DNA Gene Delivery},
author = {Davide Pantarotto and Ravi Singh and David McCarthy and Mathieu Erhardt and Jean-Paul Briand and Maurizio Prato and Kostas Kostarelos and Alberto Bianco},
url = {https://onlinelibrary.wiley.com/doi/abs/10.1002/anie.200460437},
doi = {10.1002/anie.200460437},
issn = {1521-3773},
year = {2004},
date = {2004-01-01},
urldate = {2020-03-31},
journal = {Angewandte Chemie International Edition},
volume = {43},
number = {39},
pages = {5242--5246},
abstract = {Genetic vaccination and gene therapy research could benefit from the application of carbon nanotubes. Functionalized, positively charged, water-soluble carbon nanotubes are able to penetrate into cells (see figure) and can transport plasmid DNA by formation of noncovalent DNA–nanotube complexes. Such nanotubes can be used as novel nonviral delivery systems for gene transfer.},
keywords = {Carbon nanotubes, gene delivery, I2CT, plasmid DNA, supramolecular chemistry, Team-Bianco},
pubstate = {published},
tppubtype = {article}
}
Genetic vaccination and gene therapy research could benefit from the application of carbon nanotubes. Functionalized, positively charged, water-soluble carbon nanotubes are able to penetrate into cells (see figure) and can transport plasmid DNA by formation of noncovalent DNA–nanotube complexes. Such nanotubes can be used as novel nonviral delivery systems for gene transfer.