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Gladyshev V N, Arnér E S, Berry M J, Brigelius-Flohé R, Bruford E A, Burk R F, Carlson B A, Castellano S, Chavatte L, Conrad M, Copeland P R, Diamond A M, Driscoll D M, Ferreiro A, Flohé L, Green F R, Guigó R, Handy D E, Hatfield D L, Hesketh J, Hoffmann P R, Holmgren A, Hondal R J, Howard M T, Huang K, Kim H Y, Kim I Y, Köhrle J, Krol A, Kryukov G V, Lee B J, Lee B C, Lei X G, Liu Q, Lescure A, Lobanov A V, Loscalzo J, Maiorino M, Mariotti M, Prabhu K S, Rayman M P, Rozovsky S, Salinas G, Schomburg L, Schweizer U, Simonović M, Sunde R A, Tsuji P A, Tweedie S, Ursini F, Zhang Y
Selenoprotein Gene Nomenclature. Article de journal
Dans: J Biol Chem, vol. 291, no. 46, p. 24036-24040, 2016, ISBN: 27645994.
Résumé | Liens | BibTeX | Étiquettes: function gene name genomics nomenclature selenium selenocysteine selenoprotein structure-function, LESCURE, Unité ARN
@article{,
title = {Selenoprotein Gene Nomenclature.},
author = {V N Gladyshev and E S Arnér and M J Berry and R Brigelius-Flohé and E A Bruford and R F Burk and B A Carlson and S Castellano and L Chavatte and M Conrad and P R Copeland and A M Diamond and D M Driscoll and A Ferreiro and L Flohé and F R Green and R Guigó and D E Handy and D L Hatfield and J Hesketh and P R Hoffmann and A Holmgren and R J Hondal and M T Howard and K Huang and H Y Kim and I Y Kim and J Köhrle and A Krol and G V Kryukov and B J Lee and B C Lee and X G Lei and Q Liu and A Lescure and A V Lobanov and J Loscalzo and M Maiorino and M Mariotti and K S Prabhu and M P Rayman and S Rozovsky and G Salinas and L Schomburg and U Schweizer and M Simonović and R A Sunde and P A Tsuji and S Tweedie and F Ursini and Y Zhang},
url = {https://www.ncbi.nlm.nih.gov/pubmed/27645994?dopt=Abstract},
doi = {10.1074/jbc.M116.756155},
isbn = {27645994},
year = {2016},
date = {2016-01-01},
journal = {J Biol Chem},
volume = {291},
number = {46},
pages = {24036-24040},
abstract = {The human genome contains 25 genes coding for selenocysteine-containing proteins (selenoproteins). These proteins are involved in a variety of functions, most notably redox homeostasis. Selenoprotein enzymes with known functions are designated according to these functions: TXNRD1, TXNRD2, and TXNRD3 (thioredoxin reductases), GPX1, GPX2, GPX3, GPX4 and GPX6 (glutathione peroxidases), DIO1, DIO2, and DIO3 (iodothyronine deiodinases), MSRB1 (methionine-R-sulfoxide reductase 1) and SEPHS2 (selenophosphate synthetase 2). Selenoproteins without known functions have traditionally been denoted by SEL or SEP symbols. However, these symbols are sometimes ambiguous and conflict with the approved nomenclature for several other genes. Therefore, there is a need to implement a rational and coherent nomenclature system for selenoprotein-encoding genes. Our solution is to use the root symbol SELENO followed by a letter. This nomenclature applies to SELENOF (selenoprotein F, the 15 kDa selenoprotein, SEP15), SELENOH (selenoprotein H, SELH, C11orf31), SELENOI (selenoprotein I, SELI, EPT1), SELENOK (selenoprotein K, SELK), SELENOM (selenoprotein M, SELM), SELENON (selenoprotein N, SEPN1, SELN), SELENOO (selenoprotein O, SELO), SELENOP (selenoprotein P, SeP, SEPP1, SELP), SELENOS (selenoprotein S, SELS, SEPS1, VIMP), SELENOT (selenoprotein T, SELT), SELENOV (selenoprotein V, SELV) and SELENOW (selenoprotein W, SELW, SEPW1). This system, approved by the HUGO Gene Nomenclature Committee, also resolves conflicting, missing and ambiguous designations for selenoprotein genes and is applicable to selenoproteins across vertebrates.},
keywords = {function gene name genomics nomenclature selenium selenocysteine selenoprotein structure-function, LESCURE, Unité ARN},
pubstate = {published},
tppubtype = {article}
}
The human genome contains 25 genes coding for selenocysteine-containing proteins (selenoproteins). These proteins are involved in a variety of functions, most notably redox homeostasis. Selenoprotein enzymes with known functions are designated according to these functions: TXNRD1, TXNRD2, and TXNRD3 (thioredoxin reductases), GPX1, GPX2, GPX3, GPX4 and GPX6 (glutathione peroxidases), DIO1, DIO2, and DIO3 (iodothyronine deiodinases), MSRB1 (methionine-R-sulfoxide reductase 1) and SEPHS2 (selenophosphate synthetase 2). Selenoproteins without known functions have traditionally been denoted by SEL or SEP symbols. However, these symbols are sometimes ambiguous and conflict with the approved nomenclature for several other genes. Therefore, there is a need to implement a rational and coherent nomenclature system for selenoprotein-encoding genes. Our solution is to use the root symbol SELENO followed by a letter. This nomenclature applies to SELENOF (selenoprotein F, the 15 kDa selenoprotein, SEP15), SELENOH (selenoprotein H, SELH, C11orf31), SELENOI (selenoprotein I, SELI, EPT1), SELENOK (selenoprotein K, SELK), SELENOM (selenoprotein M, SELM), SELENON (selenoprotein N, SEPN1, SELN), SELENOO (selenoprotein O, SELO), SELENOP (selenoprotein P, SeP, SEPP1, SELP), SELENOS (selenoprotein S, SELS, SEPS1, VIMP), SELENOT (selenoprotein T, SELT), SELENOV (selenoprotein V, SELV) and SELENOW (selenoprotein W, SELW, SEPW1). This system, approved by the HUGO Gene Nomenclature Committee, also resolves conflicting, missing and ambiguous designations for selenoprotein genes and is applicable to selenoproteins across vertebrates.
