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2011

Limmer Stefanie, Quintin Jessica, Hetru Charles, Ferrandon Dominique

Virulence on the fly: Drosophila melanogaster as a model genetic organism to decipher host-pathogen interactions Article de journal

Dans: Curr Drug Targets, 12 (7), p. 978–999, 2011, ISSN: 1873-5592.

Résumé | BibTeX | Étiquettes: Animal, Animals, Anti-Infective Agents, Disease Models, Drug Delivery Systems, Drug Design, Drug Resistance, ferrandon, Fungi, High-Throughput Screening Assays, Host-Pathogen Interactions, Humans, M3i, Microbial, Pseudomonas aeruginosa

2002

Pantarotto Davide, Bianco Alberto, Pellarini Federica, Tossi Alessandro, Giangaspero Anna, Zelezetsky Igor, Briand Jean-Paul, Prato Maurizio

Solid-phase synthesis of fullerene-peptides Article de journal

Dans: Journal of the American Chemical Society, 124 (42), p. 12543–12549, 2002, ISSN: 0002-7863.

Résumé | Liens | BibTeX | Étiquettes: Amino Acids, Anti-Bacterial Agents, Anti-Infective Agents, Candida albicans, Electrospray Ionization, Enkephalin, Escherichia coli, Fluorenes, Fullerenes, I2CT, Leucine, Mass, Microbial Sensitivity Tests, Oligopeptides, Spectrometry, Staphylococcus aureus, Team-Bianco

2001

Michel T, Reichhart Jean-Marc, Hoffmann Jules A, Royet Julien

Drosophila Toll is activated by Gram-positive bacteria through a circulating peptidoglycan recognition protein Article de journal

Dans: Nature, 414 (6865), p. 756–759, 2001, ISSN: 0028-0836.

Résumé | Liens | BibTeX | Étiquettes: Amino Acid, Animals, Anti-Bacterial Agents, Anti-Infective Agents, Bacillus thuringiensis, Carrier Proteins, Cell Surface, Chromosome Mapping, Enterococcus faecalis, Fungi, Genes, Gram-Positive Bacteria, Hemolymph, hoffmann, Humans, Insect, Insect Proteins, M3i, Membrane Glycoproteins, Micrococcus luteus, Mutation, Receptors, reichhart, Sequence Homology, Toll-Like Receptors

Georgel Philippe, Naitza S, Kappler Christine, Ferrandon Dominique, Zachary Daniel, Swimmer C, Kopczynski C, Duyk G, Reichhart Jean-Marc, Hoffmann Jules A

Drosophila immune deficiency (IMD) is a death domain protein that activates antibacterial defense and can promote apoptosis Article de journal

Dans: Dev. Cell, 1 (4), p. 503–514, 2001, ISSN: 1534-5807.

Résumé | BibTeX | Étiquettes: Animals, Anti-Infective Agents, Apoptosis, Bacterial Infections, Caspases, Chromosome Mapping, Cysteine Proteinase Inhibitors, DNA Damage, Female, ferrandon, Gene Expression, hoffmann, I-kappa B Kinase, Immunocompromised Host, In Situ Nick-End Labeling, Insect Proteins, M3i, Male, Mutation, Phenotype, Protein Structure, Protein-Serine-Threonine Kinases, reichhart, Tertiary

Vizioli J, Bulet Philippe, Hoffmann Jules A, Kafatos Fotis C, Müller H M, Dimopoulos G

Gambicin: a novel immune responsive antimicrobial peptide from the malaria vector Anopheles gambiae Article de journal

Dans: Proc. Natl. Acad. Sci. U.S.A., 98 (22), p. 12630–12635, 2001, ISSN: 0027-8424.

Résumé | Liens | BibTeX | Étiquettes: Animals, Anopheles, Anti-Bacterial Agents, Anti-Infective Agents, Base Sequence, Chromosome Mapping, hoffmann, Insect Proteins, Insect Vectors, M3i, Malaria, messenger, RNA

2000

Imler Jean-Luc, Hoffmann Jules A

Signaling mechanisms in the antimicrobial host defense of Drosophila Article de journal

Dans: Current Opinion in Microbiology, 3 (1), p. 16–22, 2000, ISSN: 1369-5274.

Résumé | BibTeX | Étiquettes: Animals, Anti-Infective Agents, Cell Surface, Gene Expression Regulation, Genes, hoffmann, imler, Insect, Insect Proteins, M3i, Membrane Glycoproteins, Receptors, Signal Transduction, Toll-Like Receptors

Meister Marie, Hetru Charles, Hoffmann Jules A

The antimicrobial host defense of Drosophila Article de journal

Dans: Curr. Top. Microbiol. Immunol., 248 , p. 17–36, 2000, ISSN: 0070-217X.

BibTeX | Étiquettes: Animals, Anti-Infective Agents, Fat Body, Genes, hoffmann, Insect, Insect Proteins, M3i

1999

Manfruelli P, Reichhart Jean-Marc, Steward R, Hoffmann Jules A, Lemaitre Bruno

A mosaic analysis in Drosophila fat body cells of the control of antimicrobial peptide genes by the Rel proteins Dorsal and DIF Article de journal

Dans: EMBO J., 18 (12), p. 3380–3391, 1999, ISSN: 0261-4189.

Résumé | Liens | BibTeX | Étiquettes: Animals, Anti-Infective Agents, Cell Surface, Clone Cells, DNA-Binding Proteins, Fat Body, Female, Gene Expression Regulation, Genes, hoffmann, Insect, Insect Proteins, Larva, M3i, Male, Membrane Glycoproteins, Mosaicism, Mutation, Nuclear Proteins, Phosphoproteins, Receptors, reichhart, Reporter, Signal Transduction, Toll-Like Receptors, Transcription Factors

1998

Bulet Philippe, Uttenweiler-Joseph S, Moniatte M, Dorsselaer Van A, Hoffmann Jules A

Differential display of peptides induced during the immune response of Drosophila: a matrix-assisted laser desorption ionization time-of-flight mass spectrometry study Article de journal

Dans: J. Protein Chem., 17 (6), p. 528–529, 1998, ISSN: 0277-8033.

BibTeX | Étiquettes: Animals, Anti-Infective Agents, hoffmann, M3i, Mass, Matrix-Assisted Laser Desorption-Ionization, Peptide Biosynthesis, Peptides, Spectrometry

Shahabuddin M, Fields I, Bulet Philippe, Hoffmann Jules A, Miller L H

Plasmodium gallinaceum: differential killing of some mosquito stages of the parasite by insect defensin Article de journal

Dans: Exp. Parasitol., 89 (1), p. 103–112, 1998, ISSN: 0014-4894.

Résumé | Liens | BibTeX | Étiquettes: Aedes, Animals, Anti-Infective Agents, Blood Proteins, Defensins, Diptera, hoffmann, Insect Vectors, insects, M3i, Plasmodium gallinaceum, Zygote

Levashina Elena A, Ohresser S, Lemaitre Bruno, Imler Jean-Luc

Two distinct pathways can control expression of the gene encoding the Drosophila antimicrobial peptide metchnikowin Article de journal

Dans: Journal of Molecular Biology, 278 (3), p. 515–527, 1998, ISSN: 0022-2836.

Résumé | Liens | BibTeX | Étiquettes: Animals, Anti-Infective Agents, Antimicrobial Cationic Peptides, Base Sequence, Cloning, Gene Expression Regulation, Genes, Genetic, Genetically Modified, Glycopeptides, imler, Insect, Insect Proteins, Larva, M3i, Molecular, Mutation, Peptides, Promoter Regions, Recombinant Fusion Proteins, Reporter, Restriction Mapping, Transcription

1997

Meister Marie, Lemaitre Bruno, Hoffmann Jules A

Antimicrobial peptide defense in Drosophila Article de journal

Dans: Bioessays, 19 (11), p. 1019–1026, 1997, ISSN: 0265-9247.

Résumé | Liens | BibTeX | Étiquettes: Animals, Anti-Infective Agents, Gene Expression Regulation, Genetic, hoffmann, Insect Proteins, M3i, Models, Peptides, Promoter Regions, Signal Transduction

1996

Charlet Maurice, Chernysh S, Philippe H, Hetru Charles, Hoffmann Jules A, Bulet Philippe

Innate immunity. Isolation of several cysteine-rich antimicrobial peptides from the blood of a mollusc, Mytilus edulis Article de journal

Dans: J. Biol. Chem., 271 (36), p. 21808–21813, 1996, ISSN: 0021-9258.

Résumé | BibTeX | Étiquettes: Amino Acid, Animals, Anti-Infective Agents, Antifungal Agents, Bivalvia, Blood Proteins, Chromatography, Cysteine, Defensins, High Pressure Liquid, hoffmann, M3i, Molecular Weight, Phylogeny, Sequence Homology

Fehlbaum P, Bulet Philippe, Chernysh S, Briand J P, Roussel J P, Letellier L, Hetru Charles, Hoffmann Jules A

Structure-activity analysis of thanatin, a 21-residue inducible insect defense peptide with sequence homology to frog skin antimicrobial peptides Article de journal

Dans: Proc. Natl. Acad. Sci. U.S.A., 93 (3), p. 1221–1225, 1996, ISSN: 0027-8424.

Résumé | BibTeX | Étiquettes: Amino Acid, Amphibian Proteins, Animals, Anti-Bacterial Agents, Anti-Infective Agents, Antimicrobial Cationic Peptides, Cyclic, Fungi, Gram-Negative Bacteria, Gram-Positive Bacteria, Hemiptera, hoffmann, M3i, Mass Spectrometry, Microbial Sensitivity Tests, Peptides, Ranidae, Sequence Homology, Skin, Structure-Activity Relationship

1995

Lemaitre Bruno, Meister Marie, Govind S, Georgel Philippe, Steward R, Reichhart Jean-Marc, Hoffmann Jules A

Functional analysis and regulation of nuclear import of dorsal during the immune response in Drosophila Article de journal

Dans: EMBO J., 14 (3), p. 536–545, 1995, ISSN: 0261-4189.

Résumé | BibTeX | Étiquettes: Animals, Anti-Bacterial Agents, Anti-Infective Agents, Antimicrobial Cationic Peptides, Biological Transport, Cell Nucleus, Cell Surface, DNA-Binding Proteins, Fat Body, Gene Expression Regulation, Genetic, hoffmann, Immunity, Immunohistochemistry, Insect Hormones, Insect Proteins, M3i, Melanins, Membrane Glycoproteins, Mutation, Neoplasms, Nuclear Proteins, Phosphoproteins, Receptors, reichhart, Signal Transduction, Toll-Like Receptors, Transcription, Transcription Factors

1994

Meister Marie, Braun A, Kappler Christine, Reichhart Jean-Marc, Hoffmann Jules A

Insect immunity. A transgenic analysis in Drosophila defines several functional domains in the diptericin promoter Article de journal

Dans: EMBO J., 13 (24), p. 5958–5966, 1994, ISSN: 0261-4189.

Résumé | BibTeX | Étiquettes: Animals, Anti-Infective Agents, Base Sequence, beta-Galactosidase, DNA Mutational Analysis, Female, Gene Expression Regulation, Genetic, Genetically Modified, Germ Cells, hoffmann, Insect Hormones, Insect Proteins, M3i, Male, Models, Nucleic Acid, Promoter Regions, Recombinant Fusion Proteins, reichhart, Repetitive Sequences, Transformation

1993

Georgel Philippe, Meister Marie, Kappler Christine, Lemaitre Bruno, Reichhart Jean-Marc, Hoffmann Jules A

Insect immunity: the diptericin promoter contains multiple functional regulatory sequences homologous to mammalian acute-phase response elements Article de journal

Dans: Biochem. Biophys. Res. Commun., 197 (2), p. 508–517, 1993, ISSN: 0006-291X.

Résumé | Liens | BibTeX | Étiquettes: Acute-Phase Proteins, Animals, Anti-Infective Agents, Base Sequence, Cell Line, Deoxyribonuclease I, DNA-Binding Proteins, Genetic, hoffmann, Insect Hormones, Insect Proteins, Larva, M3i, Mammals, NF-kappa B, Nucleic Acid, Oligonucleotide Probes, Polymerase Chain Reaction, Promoter Regions, Regulatory Sequences, reichhart