Imaging

@article{ciobanu_selection_2011,

title = {Selection of a synthetic glycan oligomer from a library of DNA-templated fragments against DC-SIGN and inhibition of HIV gp120 binding to dendritic cells},

author = {M Ciobanu and K T Huang and J P Daguer and S Barluenga and O Chaloin and E Schaeffer and C G Mueller and D A Mitchell and N Winssinger},

year  = {2011},

date = {2011-07-01},

journal = {Chem.Commun.(Camb.)},

number = {1364-548X (Electronic)},

abstract = {We report the synthesis of a nucleic acid-encoded carbohydrate library, its combinatorial self-assembly into 37 485 pairs and a screen against DC-SIGN leading to the identification of consensus ligand motifs. A prototypical example from the selected pairs was shown to have enhanced binding. A dendrimer incorporating the selected motifs inhibited gp120's binding to dendritic cells with higher efficiency than mannan},

keywords = {Dendritic Cells, GP120, HIV, IDENTIFICATION, inhibition, ligand, mannan, synthesis, Team-Mueller},

pubstate = {published},

tppubtype = {article}

}