Imaging

@article{,

title = {Sequence-specific cleavage of yeast tRNA(Phe) with oligonucleotides conjugated to a diimidazole construct},

author = {V Vlassov and T Abramova and T Godovikova and R Giege and V Silnikov},

url = {http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9055037},

isbn = {9055037},

year  = {1997},

date = {1997-01-01},

journal = {Antisense Nucleic Acid Drug Dev},

volume = {7},

number = {1},

pages = {39-42},

abstract = {Oligonucleotide derivatives conjugated to a chemical construction with two histamine residues imitating the catalytic center of ribonuclease A have been synthesized. In experiments with the conjugates complementary to the 3'-end and to the variable loop and the T loop of yeast tRNA(Phe), it was shown that the compounds can accomplish sequence-specific cleavage of the target RNA in physiologic conditions.},

note = {1087-2906 

Journal Article},

keywords = {Antisense/chemical synthesis/metabolism/*pharmacology  RNA, Base Sequence  Imidazoles/*chemistry  Molecular Sequence Data  Oligonucleotides, Fungal/*drug effects  RNA, Non-U.S. Gov't  Yeasts/genetics, Pancreatic/pharmacology  Support, Phe/chemistry/*drug effects/*metabolism  Ribonuclease, Transfer, Unité ARN},

pubstate = {published},

tppubtype = {article}

}