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Baron Olga Lucia, van West Pieter, Industri Benoit, Ponchet Michel, Dubreuil Géraldine, Gourbal Benjamin, Reichhart Jean-Marc, Coustau Christine

Parental transfer of the antimicrobial protein LBP/BPI protects Biomphalaria glabrata eggs against oomycete infections Journal Article

In: PLoS Pathog., 9 (12), pp. e1003792, 2013, ISSN: 1553-7374.

Abstract | Links | BibTeX | Tags: Acute-Phase Proteins, Animals, Antimicrobial Cationic Peptides, Biomphalaria, Blood Proteins, Carrier Proteins, Cell Membrane, Cell Membrane Permeability, Cloning, Escherichia coli, Female, Immunity, infection, M3i, Maternally-Acquired, Membrane Glycoproteins, Microbial Sensitivity Tests, Molecular, Oomycetes, Recombinant Proteins, reichhart, Zygote


Croker Ben, Crozat Karine, Berger Michael, Xia Yu, Sovath Sosathya, Schaffer Lana, Eleftherianos Ioannis, Imler Jean-Luc, Beutler Bruce

ATP-sensitive potassium channels mediate survival during infection in mammals and insects Journal Article

In: Nature Genetics, 39 (12), pp. 1453–1460, 2007, ISSN: 1546-1718.

Abstract | Links | BibTeX | Tags: Animals, ATP-Binding Cassette Transporters, Cloning, Coronary Vessels, Crosses, Ethylnitrosourea, Genetic, Homozygote, imler, infection, Inwardly Rectifying, KATP Channels, Lipopolysaccharides, M3i, Mice, Molecular, Mutagenesis, Potassium Channels, Sulfonylurea Receptors


Luna C, Hoa N T, Zhang J, Kanzok S M, Brown S E, Imler Jean-Luc, Knudson D L, Zheng L

Characterization of three Toll-like genes from mosquito Aedes aegypti Journal Article

In: Insect Molecular Biology, 12 (1), pp. 67–74, 2003, ISSN: 0962-1075.

Abstract | BibTeX | Tags: Aedes, Animals, Base Sequence, Cell Surface, Chimera, Cloning, Developmental, Female, Gene Expression Regulation, Genetic, imler, Insect Proteins, M3i, Male, messenger, Models, Molecular, Mutagenesis, Promoter Regions, Receptors, Reverse Transcriptase Polymerase Chain Reaction, RNA, Sequence Alignment, Signal Transduction, Site-Directed, Transfection


Wilhelm M., Fishman J. A., Pontikis R., Aubertin A. M., Wilhelm F. X.

Susceptibility of recombinant porcine endogenous retrovirus reverse transcriptase to nucleoside and non-nucleoside inhibitors Journal Article

In: Cell Mol Life Sci, 59 (12), pp. 2184-90, 2002, (1420-682x Journal Article).

Abstract | BibTeX | Tags: Acid, Amino, Animals, Calf, Chloride/metabolism, Chlorides/metabolism, Cloning, Compounds/metabolism, Data, DNA, DNA-Directed, endogenous, Gov't, H, Human, Inhibitors/*pharmacology, Magnesium, Manganese, Molecular, Non-U.S., Nucleosides/chemistry/*metabolism, P.H.S., Polymerase/chemistry/genetics/*metabolism, Polymerase/metabolism, Proteins/metabolism, Recombinant, Retroviruses/*enzymology, Reverse, Ribonuclease, RNA-Directed, Sequence, Sodium, structure, Support, Swine, Thymus/metabolism, Transcriptase, U.S.


Mueller C G, Cremer I, Paulet P E, Niida S, Maeda N, Lebeque S, Fridman W H, Sautès-Fridman C

Mannose receptor ligand-positive cells express the metalloprotease decysin in the B cell follicle Journal Article

In: Journal of Immunology (Baltimore, Md.: 1950), 167 (9), pp. 5052–5060, 2001, ISSN: 0022-1767.

Abstract | Links | BibTeX | Tags: ADAM Proteins, Amino Acid Sequence, Animals, B-Lymphocytes, C-Type, Cell Surface, Cloning, Dendritic Cells, Follicular, Germinal Center, Humans, Inbred BALB C, Lectins, ligands, Macrophage Colony-Stimulating Factor, Macrophages, Mannose-Binding Lectins, Metalloendopeptidases, Mice, Molecular, Molecular Sequence Data, Receptors, SPLEEN, Team-Mueller

Levashina Elena A, Moita L F, Blandin Stéphanie A, Vriend G, Lagueux Marie, Kafatos F C

Conserved role of a complement-like protein in phagocytosis revealed by dsRNA knockout in cultured cells of the mosquito, Anopheles gambiae Journal Article

In: Cell, 104 (5), pp. 709–718, 2001, ISSN: 0092-8674.

Abstract | BibTeX | Tags: alpha-Macroglobulins, Animals, Anopheles, blandin, Cells, Cloning, Complement C3, Cultured, DNA Fragmentation, Double-Stranded, Female, Genetic, Gram-Negative Bacteria, Hemocytes, Insect Proteins, M3i, Molecular, Nucleic Acid Denaturation, Phagocytosis, Protein Structure, RNA, Tertiary, Transcription


Wilhelm M., Boutabout M., Wilhelm F. X.

Expression of an active form of recombinant Ty1 reverse transcriptase in Escherichia coli: a fusion protein containing the C-terminal region of the Ty1 integrase linked to the reverse transcriptase-RNase H domain exhibits polymerase and RNase H activities Journal Article

In: Biochem J, 348 (Pt 2), pp. 337-42, 2000, (0264-6021 Journal Article).

Abstract | BibTeX | Tags: &, Acid, affinity, Alignment, Amino, Calf, cerevisiae/*enzymology/*genetics, Chromatography, Cloning, Codon, coli, Comparative, Data, DNA, DNA/metabolism, Escherichia, Frames, Fusion, Genetic, Gov't, H, Heteroduplexes/metabolism, HIV-1, Homology, Integrases/chemistry/metabolism, Kinetics, Molecular, Non-U.S., Nucleic, Open, Polymerase/chemistry/isolation, Proteins/chemistry/isolation, purification/*metabolism, purification/metabolism, Reading, Recombinant, Retroelements/*genetics, Reverse, Ribonuclease, RNA-Directed, RNA/metabolism, Saccharomyces, Sequence, Study, Support, Templates, Terminator, Thymus/isolation, Transcriptase/chemistry


Lowenberger C A, Smartt C T, Bulet Philippe, Ferdig M T, Severson D W, Hoffmann Jules A, Christensen B M

Insect immunity: molecular cloning, expression, and characterization of cDNAs and genomic DNA encoding three isoforms of insect defensin in Aedes aegypti Journal Article

In: Insect Mol. Biol., 8 (1), pp. 107–118, 1999, ISSN: 0962-1075.

Abstract | BibTeX | Tags: Aedes, Amino Acid, Animals, Base Sequence, Blotting, Chromosome Mapping, Cloning, Complementary, Defensins, DNA, Gene Expression, Hemolymph, hoffmann, M3i, Molecular, Northern, Protein Isoforms, Proteins, Sequence Homology


Uttenweiler-Joseph S, Moniatte M, Lagueux Marie, Dorsselaer Van A, Hoffmann Jules A, Bulet Philippe

Differential display of peptides induced during the immune response of Drosophila: a matrix-assisted laser desorption ionization time-of-flight mass spectrometry study Journal Article

In: Proc. Natl. Acad. Sci. U.S.A., 95 (19), pp. 11342–11347, 1998, ISSN: 0027-8424.

Abstract | BibTeX | Tags: Animals, bacteria, Chromatography, Cloning, Hemolymph, High Pressure Liquid, hoffmann, Immunity, Insect Proteins, M3i, Mass, Matrix-Assisted Laser Desorption-Ionization, messenger, Molecular, Peptides, Protein Precursors, RNA, Sequence Analysis, Spectrometry, Time Factors

Motorin Y., Keith G., Simon C., Foiret D., Simos G., Hurt E., Grosjean H.

The yeast tRNA:pseudouridine synthase Pus1p displays a multisite substrate specificity Journal Article

In: RNA, 4 (7), pp. 856-69, 1998, (1355-8382 Journal Article).

Abstract | BibTeX | Tags: *RNA, cerevisiae, Cloning, Fractions/metabolism, Fungal, Fungal/metabolism, Gov't, Hydro-Lyases/biosynthesis/genetics/*metabolism, Molecular, Mutation, Non-U.S., Plant/metabolism, post-transcriptional, Precursors/*metabolism, Processing, Proteins/biosynthesis, Proteins/biosynthesis/genetics/metabolism, Pseudouridine/*biosynthesis, Recombinant, RNA, Saccharomyces, Specificity, Subcellular, Substrate, Support, Transfer/*metabolism

Levashina Elena A, Ohresser S, Lemaitre Bruno, Imler Jean-Luc

Two distinct pathways can control expression of the gene encoding the Drosophila antimicrobial peptide metchnikowin Journal Article

In: Journal of Molecular Biology, 278 (3), pp. 515–527, 1998, ISSN: 0022-2836.

Abstract | Links | BibTeX | Tags: Animals, Anti-Infective Agents, Antimicrobial Cationic Peptides, Base Sequence, Cloning, Gene Expression Regulation, Genes, Genetic, Genetically Modified, Glycopeptides, imler, Insect, Insect Proteins, Larva, M3i, Molecular, Mutation, Peptides, Promoter Regions, Recombinant Fusion Proteins, Reporter, Restriction Mapping, Transcription


Richman A M, Bulet Philippe, Hetru Charles, Barillas-Mury Carolina, Hoffmann Jules A, Kafalos Fotis C

Inducible immune factors of the vector mosquito Anopheles gambiae: biochemical purification of a defensin antibacterial peptide and molecular cloning of preprodefensin cDNA Journal Article

In: Insect Mol. Biol., 5 (3), pp. 203–210, 1996, ISSN: 0962-1075.

Abstract | BibTeX | Tags: Amino Acid, Animals, Anopheles, Base Sequence, Blood Bactericidal Activity, Blood Proteins, Cloning, Complementary, Defensins, DNA, Escherichia coli, Female, Gene Expression, Genes, hoffmann, Insect, Insect Vectors, Larva, M3i, Micrococcus luteus, Molecular, Sequence Homology


Levashina Elena A, Ohresser S, Bulet Philippe, Reichhart Jean-Marc, Hetru Charles, Hoffmann Jules A

Metchnikowin, a novel immune-inducible proline-rich peptide from Drosophila with antibacterial and antifungal properties Journal Article

In: Eur. J. Biochem., 233 (2), pp. 694–700, 1995, ISSN: 0014-2956.

Abstract | BibTeX | Tags: Animals, Anti-Bacterial Agents, Antifungal Agents, Antimicrobial Cationic Peptides, bacteria, Base Sequence, Cells, Chromosome Mapping, Cloning, Cultured, Genetic, hoffmann, M3i, Molecular, Peptides, Proline, reichhart, Transcription

Heyman T., Agoutin B., Friant S., Wilhelm F. X., Wilhelm M. L.

Plus-strand DNA synthesis of the yeast retrotransposon Ty1 is initiated at two sites, PPT1 next to the 3' LTR and PPT2 within the pol gene. PPT1 is sufficient for Ty1 transposition Journal Article

In: J Mol Biol, 253 (2), pp. 291-303, 1995, (0022-2836 Journal Article).

Abstract | BibTeX | Tags: *DNA, *Genes, *Repetitive, *Retroelements, Acid, Base, C/analysis, cerevisiae/genetics/*virology, Chain, Cloning, Data, DNA, Fungal, Fungal/biosynthesis, Genes, Genetic, Genome, Gov't, Mapping, Molecular, Non-U.S., Nucleic, pol, Poly, Polymerase, Primers, Reaction, Replication, Restriction, Saccharomyces, Sequence, Sequences, Support, Transcription, Viral, Viral/*biosynthesis

Cura V, Kern D, Mitschler A, Moras D

Crystallization of threonyl-tRNA synthetase from Thermus thermophilus and preliminary crystallographic data Journal Article

In: FEBS Lett, 374 (1), pp. 110-112, 1995, ISBN: 7589494, (0014-5793 Journal Article).

Abstract | Links | BibTeX | Tags: Cloning, Molecular Crystallization Crystallography, Non-U.S. Gov't Temperature Thermus thermophilus/*enzymology Threonine-tRNA Ligase/*chemistry/genetics, Unité ARN, X-Ray Escherichia coli Solubility Support


Fehlbaum P, Bulet Philippe, Michaut L, Lagueux Marie, Broekaert W F, Hetru Charles, Hoffmann Jules A

Insect immunity. Septic injury of Drosophila induces the synthesis of a potent antifungal peptide with sequence homology to plant antifungal peptides Journal Article

In: J. Biol. Chem., 269 (52), pp. 33159–33163, 1994, ISSN: 0021-9258.

Abstract | BibTeX | Tags: Amino Acid, Animals, Antifungal Agents, Base Sequence, Cloning, Complementary, DNA, hoffmann, Insect Proteins, M3i, Male, messenger, Microbial Sensitivity Tests, Molecular, Peptide Biosynthesis, Peptides, Plants, Protein Biosynthesis, Protein Precursors, Proteins, RNA, Sequence Homology

Dimarcq Jean-Luc, Hoffmann Danièle, Meister Marie, Bulet Philippe, Lanot R, Reichhart Jean-Marc, Hoffmann Jules A

Characterization and transcriptional profiles of a Drosophila gene encoding an insect defensin. A study in insect immunity Journal Article

In: Eur. J. Biochem., 221 (1), pp. 201–209, 1994, ISSN: 0014-2956.

Abstract | BibTeX | Tags: Animals, Base Sequence, Blood Proteins, Chromosome Mapping, Cloning, Complementary, Defensins, DNA, Gene Expression, Genetic, Gram-Positive Bacteria, hoffmann, Larva, M3i, Molecular, Molecular Structure, Nucleic Acid, Protein Precursors, Regulatory Sequences, reichhart, Transcription

Wilhelm M., Wilhelm F. X., Keith G., Agoutin B., Heyman T.

Yeast Ty1 retrotransposon: the minus-strand primer binding site and a cis-acting domain of the Ty1 RNA are both important for packaging of primer tRNA inside virus-like particles Journal Article

In: Nucleic Acids Res, 22 (22), pp. 4560-5, 1994, (0305-1048 Journal Article).

Abstract | BibTeX | Tags: Acid, Amino, Base, Binding, cerevisiae/*genetics, Cloning, Data, Fungal/*genetics, Genetic, Gov't, Met/*genetics, Molecular, Mutation/physiology, Non-U.S., Retroelements/*genetics/physiology, Retroviridae/genetics, RNA, RNA/*genetics, Saccharomyces, Sequence, Sites, Support, Transcription, Transfer


Bulet Philippe, Dimarcq Jean-Luc, Hetru Charles, Lagueux Marie, Charlet Maurice, Hegy G, Dorsselaer Alan Van, Hoffmann Jules A

A novel inducible antibacterial peptide of Drosophila carries an O-glycosylated substitution Journal Article

In: J. Biol. Chem., 268 (20), pp. 14893–14897, 1993, ISSN: 0021-9258.

Abstract | BibTeX | Tags: Animals, Anti-Bacterial Agents, Base Sequence, Carbohydrates, Cloning, DNA, Escherichia coli, Gas Chromatography-Mass Spectrometry, Glycopeptides, Glycosylation, hoffmann, M3i, Molecular

Kappler Christine, Meister Marie, Lagueux Marie, Gateff E, Hoffmann Jules A, Reichhart Jean-Marc

Insect immunity. Two 17 bp repeats nesting a kappa B-related sequence confer inducibility to the diptericin gene and bind a polypeptide in bacteria-challenged Drosophila Journal Article

In: EMBO J., 12 (4), pp. 1561–1568, 1993, ISSN: 0261-4189.

Abstract | BibTeX | Tags: Animals, Anti-Bacterial Agents, Base Sequence, Cloning, Gene Expression Regulation, Genes, Genetic, Genetically Modified, hoffmann, Insect, Insect Hormones, Insect Proteins, Lipopolysaccharides, M3i, messenger, Molecular, NF-kappa B, Nucleic Acid, Oligodeoxyribonucleotides, Promoter Regions, Regulatory Sequences, reichhart, RNA, Transfection

Santos M. A., Keith G., Tuite M. F.

Non-standard translational events in Candida albicans mediated by an unusual seryl-tRNA with a 5'-CAG-3' (leucine) anticodon Journal Article

In: EMBO J, 12 (2), pp. 607-16, 1993, (0261-4189 Journal Article).

Abstract | BibTeX | Tags: *Anticodon, *Translation, &, Acid, albicans/*genetics, Base, Candida, Cloning, Conformation, Data, DNA, Fungal, Fungal/chemistry/genetics/isolation, Genes, Genetic, Gov't, Leucine/*genetics, Molecular, Non-U.S., Nucleic, purification, RNA, Sequence, Ser/chemistry/*genetics/isolation, Support, Transfer


Dimarcq Jean-Luc, Zachary Daniel, Hoffmann Jules A, Hoffmann Danièle, Reichhart Jean-Marc

Insect immunity: expression of the two major inducible antibacterial peptides, defensin and diptericin, in Phormia terranovae Journal Article

In: EMBO J., 9 (8), pp. 2507–2515, 1990, ISSN: 0261-4189.

Abstract | BibTeX | Tags: Animals, Anti-Bacterial Agents, Base Sequence, Blood Proteins, Cloning, Defensins, Diptera, Gene Expression, hoffmann, Insect Hormones, Insect Proteins, Larva, M3i, Molecular, Nucleic Acid Hybridization, Oligonucleotide Probes, Protein Conformation, reichhart

Wicker C, Reichhart Jean-Marc, Hoffmann Danièle, Hultmark D, Samakovlis C, Hoffmann Jules A

Insect immunity. Characterization of a Drosophila cDNA encoding a novel member of the diptericin family of immune peptides Journal Article

In: J. Biol. Chem., 265 (36), pp. 22493–22498, 1990, ISSN: 0021-9258.

Abstract | BibTeX | Tags: Animals, Anti-Bacterial Agents, Base Sequence, Cloning, Diptera, DNA, Escherichia coli, hoffmann, Insect Hormones, Insect Proteins, M3i, Molecular, Multigene Family, Nucleic Acid, Oligonucleotide Probes, reichhart, Sequence Homology