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Karttunen Sarah, Duffield Michael, Scrimgeour Nathan R, Squires Lauren, Lim Wai Li, Dallas Mark L, Scragg Jason L, Chicher Johana, Dave Keyur A, Whitelaw Murray L, Peers Chris, Gorman Jeffrey J, Gleadle Jonathan M, Rychkov Grigori Y, Peet Daniel J

Oxygen-dependent hydroxylation by FIH regulates the TRPV3 ion channel. Journal Article

In: Journal of cell science, vol. 128, no. 2, pp. 225–231, 2015, ISSN: 1477-9137 0021-9533, (Place: England).

Abstract | Links | BibTeX | Tags: alpha Subunit/genetics/*metabolism, Amino Acid Sequence, Ankyrin Repeat/genetics, Cell Hypoxia/*genetics, FIH, HEK293 Cells, Humans, Hydroxylation, Hydroxylation/genetics, Hypoxia, Hypoxia-Inducible Factor 1, Mixed Function Oxygenases/antagonists & inhibitors/genetics/*metabolism, Mutation, Oxygen/metabolism, PPSE, Protein Binding, Repressor Proteins/antagonists & inhibitors/genetics/*metabolism, TRPV Cation Channels/genetics/*metabolism, TRPV3


Wilkins Sarah E, Hyvärinen Jaana, Chicher Johana, Gorman Jeffrey J, Peet Daniel J, Bilton Rebecca L, Koivunen Peppi

Differences in hydroxylation and binding of Notch and HIF-1alpha demonstrate substrate selectivity for factor inhibiting HIF-1 (FIH-1). Journal Article

In: The international journal of biochemistry & cell biology, vol. 41, no. 7, pp. 1563–1571, 2009, ISSN: 1878-5875 1357-2725, (Place: Netherlands).

Abstract | Links | BibTeX | Tags: alpha Subunit/*metabolism, Amino Acid Sequence, Animals, Asparagine/metabolism, Humans, Hydroxylation, Hypoxia-Inducible Factor 1, Kinetics, Mice, Mixed Function Oxygenases, Molecular Sequence Data, Notch/chemistry/*metabolism, Oxygen/metabolism, Peptides/chemistry/metabolism, PPSE, Protein Binding, Receptors, Recombinant Proteins/metabolism, Repressor Proteins/*metabolism, Substrate Specificity


Meister Marie F, Dimarcq Jean-Luc, Kappler Christine, Hetru Charles, Lagueux Marie, Lanot R, Luu B, Hoffmann Jules A

Conversion of a radiolabelled ecdysone precursor, 2,22,25-trideoxyecdysone, by embryonic and larval tissues of Locusta migratoria Journal Article

In: Mol. Cell. Endocrinol., vol. 41, no. 1, pp. 27–44, 1985, ISSN: 0303-7207.

Abstract | BibTeX | Tags: Abdomen, Animals, Cholestenones, Chromatography, Ecdysone, Epidermis, Fat Body, Grasshoppers, Head, High Pressure Liquid, hoffmann, Hydroxylation, Larva, M3i, Malpighian Tubules, Thorax


Feyereisen R, Lagueux Marie, Hoffmann Jules A

Dynamics of ecdysone metabolism after ingestion and injection in Locusta migratoria Journal Article

In: Gen. Comp. Endocrinol., vol. 29, no. 3, pp. 319–327, 1976, ISSN: 0016-6480.

BibTeX | Tags: Animals, Ecdysone, Grasshoppers, hoffmann, Hydroxylation, Injections, Intestines, Larva, M3i, Malpighian Tubules, Oral


Hoffmann Jules A, Koolman J, Karlson P, Joly P

Molting hormone titer and metabolic fate of injected ecdysone during the fifth larval instar and in adults of Locusta migratoria (Orthoptera) Journal Article

In: Gen. Comp. Endocrinol., vol. 22, no. 1, pp. 90–97, 1974, ISSN: 0016-6480.

BibTeX | Tags: Age Factors, Animals, Chromatography, Ecdysone, Feces, Grasshoppers, hoffmann, Hydroxylation, Invertebrate Hormones, Larva, M3i, Thin Layer, Time Factors, Tritium