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2021

Arquier Nathalie, Bjordal Marianne, Hammann Philippe, Kuhn Lauriane, Léopold Pierre

Brain adiponectin signaling controls peripheral insulin response in Drosophila Journal Article

In: Nature Communications, 12 (1), pp. 5633, 2021, ISSN: 2041-1723.

Abstract | Links | BibTeX | Tags: Adiponectin, Animals, Brain, Cell Line, Drosophila melanogaster, Drosophila Proteins, Energy Metabolism, Genetically Modified, Hemolymph, Homeostasis, Insulin, Juvenile Hormones, Larva, Neurons, PPSE, Receptors, Signal Transduction

2013

Fukuyama Hidehiro, Verdier Yann, Guan Yongsheng, Makino-Okamura Chieko, Shilova Victoria, Liu Xi, Maksoud Elie, Matsubayashi Jun, Haddad Iman, Spirohn Kerstin, Ono Kenichiro, Hetru Charles, Rossier Jean, Ideker Trey, Boutros Michael, Vinh Joëlle, Hoffmann Jules A

Landscape of protein-protein interactions in Drosophila immune deficiency signaling during bacterial challenge Journal Article

In: Proc. Natl. Acad. Sci. U.S.A., 110 (26), pp. 10717–10722, 2013, ISSN: 1091-6490.

Abstract | Links | BibTeX | Tags: Amino Acid, Animals, Chromatin Assembly and Disassembly, Escherichia coli, functional proteomics, Genes, Genetically Modified, Histone Acetyltransferases, hoffmann, Host-Pathogen Interactions, Humans, IMD interactome, Insect, M3i, Models, Molecular, Protein Interaction Maps, Sequence Homology, Signal Transduction, small ubiquitin-like modifier

2011

Limmer Stefanie, Haller Samantha, Drenkard Eliana, Lee Janice, Yu Shen, Kocks Christine, Ausubel Frederick M, Ferrandon Dominique

Pseudomonas aeruginosa RhlR is required to neutralize the cellular immune response in a Drosophila melanogaster oral infection model Journal Article

In: Proc. Natl. Acad. Sci. U.S.A., 108 (42), pp. 17378–17383, 2011, ISSN: 1091-6490.

Abstract | Links | BibTeX | Tags: Animal, Animals, Bacteremia, Bacterial Proteins, Cellular, Disease Models, ferrandon, Genes, Genetically Modified, Hemolymph, Host-Pathogen Interactions, Immunity, Insect, M3i, Mutation, Oral, Pseudomonas aeruginosa, Pseudomonas Infections, Quorum Sensing, Trans-Activators, Viral, Virulence

2009

Berry Bassam, Deddouche Safia, Kirschner Doris, Imler Jean-Luc, Antoniewski Christophe

Viral suppressors of RNA silencing hinder exogenous and endogenous small RNA pathways in Drosophila Journal Article

In: PloS One, 4 (6), pp. e5866, 2009, ISSN: 1932-6203.

Abstract | Links | BibTeX | Tags: Animals, Antiviral Agents, Crosses, Double-Stranded, Gene Silencing, Genetic, Genetically Modified, Heterozygote, imler, Invertebrate, M3i, Photoreceptor Cells, Reverse Transcriptase Polymerase Chain Reaction, RNA, RNA Interference, Transgenes

Cronin Shane J F, Nehme Nadine T, Limmer Stefanie, Liegeois Samuel, Pospisilik Andrew J, Schramek Daniel, Leibbrandt Andreas, de Simoes Ricardo Matos, Gruber Susanne, Puc Urszula, Ebersberger Ingo, Zoranovic Tamara, Neely Gregory G, von Haeseler Arndt, Ferrandon Dominique, Penninger Josef M

Genome-wide RNAi screen identifies genes involved in intestinal pathogenic bacterial infection Journal Article

In: Science, 325 (5938), pp. 340–343, 2009, ISSN: 1095-9203.

Abstract | Links | BibTeX | Tags: *Genome, *RNA Interference, Animal, Animals, Cell Proliferation, Drosophila melanogaster/*genetics/immunology/*microbiology, Drosophila Proteins/genetics/metabolism, Epithelial Cells, Epithelial Cells/cytology/physiology, ferrandon, Genetically Modified, Genome, Hemocytes, Hemocytes/immunology/metabolism/microbiology, Homeostasis, Immunity, Innate, Innate/*genetics, Insect, Intestinal Mucosa, Intestinal Mucosa/cytology/immunology/metabolism/microbiology, Janus Kinases, Janus Kinases/genetics/metabolism, M3i, Models, RNA Interference, Serratia Infections, Serratia Infections/genetics/*immunology/microbiology, Serratia marcescens, Serratia marcescens/*immunology/physiology, Signal Transduction, STAT Transcription Factors, STAT Transcription Factors/genetics/metabolism, Stem Cells, Stem Cells/cytology/physiology

2008

Deddouche Safia, Matt Nicolas, Budd Aidan, Mueller Stefanie, Kemp Cordula, Galiana-Arnoux Delphine, Dostert Catherine, Antoniewski Christophe, Hoffmann Jules A, Imler Jean-Luc

The DExD/Ħ-box helicase Dicer-2 mediates the induction of antiviral activity in drosophila Journal Article

In: Nature Immunology, 9 (12), pp. 1425–1432, 2008, ISSN: 1529-2916.

Abstract | Links | BibTeX | Tags: Amino Acid, Animals, Electrophoresis, Fat Body, Gene Expression Regulation, Genetic, Genetically Modified, hoffmann, Humans, imler, M3i, matt, Phylogeny, Polyacrylamide Gel, Reverse Transcriptase Polymerase Chain Reaction, Ribonuclease III, RNA Helicases, Sequence Homology, Transcription, Virus Diseases

Chamy L El, Leclerc V, Caldelari I, Reichhart J-M

Sensing of 'danger signals' and pathogen-associated molecular patterns defines binary signaling pathways 'upstream' of Toll Journal Article

In: Nat. Immunol., 9 (10), pp. 1165–1170, 2008, ISSN: 1529-2916.

Abstract | Links | BibTeX | Tags: Animals, Fungi, Genetically Modified, Gram-Positive Bacteria, Gram-Positive Bacterial Infections, In Situ Hybridization, M3i, Mycoses, Pattern Recognition, Peptide Hydrolases, Receptors, reichhart, ROMBY, Serine Endopeptidases, Signal Transduction, Toll-Like Receptors, Unité ARN

2006

Galiana-Arnoux Delphine, Dostert Catherine, Schneemann Anette, Hoffmann Jules A, Imler Jean-Luc

Essential function in vivo for Dicer-2 in host defense against RNA viruses in drosophila Journal Article

In: Nature Immunology, 7 (6), pp. 590–597, 2006, ISSN: 1529-2908.

Abstract | Links | BibTeX | Tags: Animals, Genetically Modified, hoffmann, imler, M3i, Mutation, Nodaviridae, Ribonuclease III, RNA, RNA Helicases, RNA Interference, RNA Viruses, Viral, Viral Proteins, Virus Replication

2005

Dostert Catherine, Jouanguy Emmanuelle, Irving Phil, Troxler Laurent, Galiana-Arnoux Delphine, Hetru Charles, Hoffmann Jules A, Imler Jean-Luc

The Jak-STAT signaling pathway is required but not sufficient for the antiviral response of drosophila Journal Article

In: Nature Immunology, 6 (9), pp. 946–953, 2005, ISSN: 1529-2908.

Abstract | Links | BibTeX | Tags: Animals, bioinformatic, DNA-Binding Proteins, Genetic, Genetically Modified, hoffmann, imler, Insect Viruses, Janus Kinase 1, M3i, Male, Oligonucleotide Array Sequence Analysis, Promoter Regions, Protein-Tyrosine Kinases, Signal Transduction, STAT1 Transcription Factor, Trans-Activators

2003

Kambris Zakaria, Bilak Hana, D'Alessandro Rosalba, Belvin Marcia, Imler Jean-Luc, Capovilla Maria

DmMyD88 controls dorsoventral patterning of the Drosophila embryo Journal Article

In: EMBO reports, 4 (1), pp. 64–69, 2003, ISSN: 1469-221X.

Abstract | Links | BibTeX | Tags: Adaptor Proteins, Alleles, Animals, Antigens, Base Sequence, Cell Surface, Complementary, Developmental, Differentiation, DNA, DNA Transposable Elements, Egg Proteins, Embryo, Exons, Female, Gene Expression Regulation, Genetically Modified, Genotype, imler, Immunity, Immunologic, Innate, Insertional, M3i, Male, messenger, Morphogenesis, Mutagenesis, Myeloid Differentiation Factor 88, Nonmammalian, Oocytes, Protein Biosynthesis, Protein Structure, Receptors, Reverse Transcriptase Polymerase Chain Reaction, RNA, Signal Transducing, Tertiary, Toll-Like Receptors, Zygote

2002

Reichhart Jean-Marc, Ligoxygakis Petros, Naitza Silvia, Woerfel Gertrud, Imler Jean-Luc, Gubb David

Splice-activated UAS hairpin vector gives complete RNAi knockout of single or double target transcripts in Drosophila melanogaster Journal Article

In: Genesis (New York, N.Y.: 2000), 34 (1-2), pp. 160–164, 2002, ISSN: 1526-954X.

Links | BibTeX | Tags: Animals, DNA Transposable Elements, DNA-Binding Proteins, Enhancer Elements, Genetic, Genetic Vectors, Genetically Modified, imler, M3i, reichhart, Saccharomyces cerevisiae Proteins, Transcription Factors

Tauszig-Delamasure Servane, Bilak Hana, Capovilla Maria, Hoffmann Jules A, Imler Jean-Luc

Drosophila MyD88 is required for the response to fungal and Gram-positive bacterial infections Journal Article

In: Nature Immunology, 3 (1), pp. 91–97, 2002, ISSN: 1529-2908.

Abstract | Links | BibTeX | Tags: Adaptor Proteins, Amino Acid, Animals, Antigens, Antimicrobial Cationic Peptides, Cell Surface, Chromosome Mapping, Differentiation, Disease Susceptibility, Enterococcus faecalis, Epistasis, Escherichia coli, Female, Gene Expression Regulation, Genes, Genetic, Genetically Modified, Gram-Negative Bacteria, hoffmann, Hypocreales, imler, Immunologic, Insect, Insect Proteins, M3i, Membrane Glycoproteins, Micrococcus luteus, Myeloid Differentiation Factor 88, Protein Structure, Protein-Serine-Threonine Kinases, Receptors, Recombinant Fusion Proteins, Sequence Alignment, Sequence Homology, Signal Transducing, Tertiary, Toll-Like Receptors, Transfection

2000

Basset A, Khush R S, Braun A, Gardan L, Boccard F, Hoffmann Jules A, Lemaitre Bruno

The phytopathogenic bacteria Erwinia carotovora infects Drosophila and activates an immune response Journal Article

In: Proc. Natl. Acad. Sci. U.S.A., 97 (7), pp. 3376–3381, 2000, ISSN: 0027-8424.

Abstract | Links | BibTeX | Tags: Animals, Bacterial, Gene Expression Regulation, Genetically Modified, hoffmann, Insect Proteins, Larva, M3i, Pectobacterium carotovorum

1998

Levashina Elena A, Ohresser S, Lemaitre Bruno, Imler Jean-Luc

Two distinct pathways can control expression of the gene encoding the Drosophila antimicrobial peptide metchnikowin Journal Article

In: Journal of Molecular Biology, 278 (3), pp. 515–527, 1998, ISSN: 0022-2836.

Abstract | Links | BibTeX | Tags: Animals, Anti-Infective Agents, Antimicrobial Cationic Peptides, Base Sequence, Cloning, Gene Expression Regulation, Genes, Genetic, Genetically Modified, Glycopeptides, imler, Insect, Insect Proteins, Larva, M3i, Molecular, Mutation, Peptides, Promoter Regions, Recombinant Fusion Proteins, Reporter, Restriction Mapping, Transcription

1994

Meister Marie, Braun A, Kappler Christine, Reichhart Jean-Marc, Hoffmann Jules A

Insect immunity. A transgenic analysis in Drosophila defines several functional domains in the diptericin promoter Journal Article

In: EMBO J., 13 (24), pp. 5958–5966, 1994, ISSN: 0261-4189.

Abstract | BibTeX | Tags: Animals, Anti-Infective Agents, Base Sequence, beta-Galactosidase, DNA Mutational Analysis, Female, Gene Expression Regulation, Genetic, Genetically Modified, Germ Cells, hoffmann, Insect Hormones, Insect Proteins, M3i, Male, Models, Nucleic Acid, Promoter Regions, Recombinant Fusion Proteins, reichhart, Repetitive Sequences, Transformation

1993

Kappler Christine, Meister Marie, Lagueux Marie, Gateff E, Hoffmann Jules A, Reichhart Jean-Marc

Insect immunity. Two 17 bp repeats nesting a kappa B-related sequence confer inducibility to the diptericin gene and bind a polypeptide in bacteria-challenged Drosophila Journal Article

In: EMBO J., 12 (4), pp. 1561–1568, 1993, ISSN: 0261-4189.

Abstract | BibTeX | Tags: Animals, Anti-Bacterial Agents, Base Sequence, Cloning, Gene Expression Regulation, Genes, Genetic, Genetically Modified, hoffmann, Insect, Insect Hormones, Insect Proteins, Lipopolysaccharides, M3i, messenger, Molecular, NF-kappa B, Nucleic Acid, Oligodeoxyribonucleotides, Promoter Regions, Regulatory Sequences, reichhart, RNA, Transfection