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123 entries « 3 of 3 »

2007

Bodlenner A, Alix A, Weibel J M, Pale P, Ennifar E, Paillart J C, Walter P, Marquet R, Dumas P

Synthesis of a neamine dimer targeting the dimerization initiation site of HIV-1 RNA Journal Article

In: Org Lett, vol. 9, no. 22, pp. 4415-4418, 2007, ISBN: 17915882.

Abstract | Links | BibTeX | Tags: ENNIFAR, MARQUET, PAILLART, Unité ARN

Ennifar E, Paillart J C, Bernacchi S, Walter P, Pale P, Decout J L, Marquet R, Dumas P

A structure-based approach for targeting the HIV-1 genomic RNA dimerization initiation site Journal Article

In: Biochimie, vol. 89, no. 10, pp. 1195-1203, 2007, ISBN: 17434658.

Abstract | Links | BibTeX | Tags: ENNIFAR, MARQUET, PAILLART, Unité ARN

Ali M B, Chaminade F, Kanevsky I, Ennifar E, Josset L, Ficheux D, Darlix J L, Fosse P

Structural requirements for nucleocapsid protein-mediated dimerization of avian leukosis virus RNA Journal Article

In: J Mol Biol, vol. 372, no. 4, pp. 1082-96, 2007, ISBN: 17706668.

Abstract | Links | BibTeX | Tags: DUMAS, ENNIFAR, Unité ARN

Bernacchi S, Freisz S, Maechling C, Spiess B, Marquet R, Dumas P, Ennifar E

Aminoglycoside binding to the HIV-1 RNA dimerization initiation site: thermodynamics and effect on the kissing-loop to duplex conversion Journal Article

In: Nucleic Acids Res, vol. 35, no. 21, pp. 7128-39, 2007, ISBN: 17942426, (1362-4962 (Electronic)).

Abstract | Links | BibTeX | Tags: DUMAS, ENNIFAR, MARQUET, Unité ARN

Ennifar E, Bernacchi S, Wolff P, Dumas P

Influence of C-5 halogenation of uridines on hairpin versus duplex RNA folding. Journal Article

In: RNA, vol. 13, no. 9, pp. 1445-52, 2007, ISBN: 17630326.

Abstract | Links | BibTeX | Tags: ENNIFAR, MARQUET, RNA HIV fluorescence halogen crystal, Unité ARN

Olieric V, Ennifar E, Meents A, Fleurant M, Besnard C, Pattison P, Schiltz M, Schulze-Briese C, Dumas P

Using X-ray absorption spectra to monitor specific radiation damage to anomalously scattering atoms in macromolecular crystallography Journal Article

In: Acta Crystallogr D Biol Crystallogr, vol. 63, no. Pt 7, pp. 759-68, 2007, ISBN: 17582167.

Abstract | Links | BibTeX | Tags: DUMAS, ENNIFAR, Unité ARN

Reblova K, Fadrna E, Sarzynska J, Kulinski T, Kulhanek P, Ennifar E, Koca J, Sponer J

Conformations of Flanking Bases in HIV-1 RNA DIS Kissing Complexes Studied by Molecular Dynamics Journal Article

In: Biophys J, vol. 93, no. 11, pp. 3932-3949, 2007, ISBN: 17704156, (0006-3495 (Print) Journal article).

Abstract | Links | BibTeX | Tags: DUMAS, ENNIFAR, Unité ARN

2006

Ennifar E, Dumas P

Polymorphism of bulged-out residues in HIV-1 RNA DIS kissing complex and structure comparison with solution studies Journal Article

In: J Mol Biol, vol. 356, no. 3, pp. 771-782, 2006, ISBN: 16403527, (0022-2836 (Print) Journal Article).

Abstract | Links | BibTeX | Tags: DUMAS, ENNIFAR, Unité ARN

Ennifar E, Paillart J C, Bodlenner A, Walter P, Weibel J M, Aubertin A M, Pale P, Dumas P, Marquet R

Targeting the dimerization initiation site of HIV-1 RNA with aminoglycosides: from crystal to cell Journal Article

In: Nucleic Acids Research, vol. 34, no. 8, pp. 2328-39, 2006.

Abstract | Links | BibTeX | Tags: Aminoglycosides/*chemistry Anti-HIV Agents/*chemistry Binding Sites Cell Line Crystallography, ENNIFAR, MARQUET, Molecular RNA, Non-U.S. Gov't Virion/chemistry, PAILLART, Unité ARN, Viral/*chemistry Research Support, X-Ray Dimerization Drug Delivery Systems HIV-1/*genetics Humans Models

2005

Ennifar E, Basquin J, Birkenbihl R, Suck D

Purification, crystallization and preliminary X-ray diffraction studies of the archaeal virus resolvase SIRV2 Journal Article

In: Acta Crystallogr F Struct Biol Commun, vol. 61, no. Pt 5, pp. 507-509, 2005, ISBN: 16511081, (1744-3091 (Electronic) Journal Article).

Abstract | Links | BibTeX | Tags: DUMAS, ENNIFAR, Unité ARN

Bernacchi S, Ennifar E, Toth K, Walter P, Langowski J, Dumas P

Mechanism of hairpin-duplex conversion for the HIV-1 dimerization initiation site Journal Article

In: J Biol Chem, vol. 280, no. 48, pp. 40112-40121, 2005, ISBN: 16169845, (0021-9258 (Print) Journal Article).

Abstract | Links | BibTeX | Tags: Base Sequence Binding Sites Crystallography, Drug Electrophoresis Genome, ENNIFAR, Fluorescence Spectrophotometry Temperature Thermodynamics Time Factors Ultraviolet Rays Virus Replication, MARQUET, Non-U.S. Gov't Spectrometry, PAILLART, Unité ARN, Viral HIV-1/*chemistry Kinetics Molecular Sequence Data *Nucleic Acid Conformation Protein Binding RNA/chemistry RNA, Viral/*chemistry Research Support, X-Ray Dimerization Dose-Response Relationship

Gaied N Ben, Glasser N, Ramalanjaona N, Beltz H, Wolff P, Marquet R, Burger A, Mely Y

8-vinyl-deoxyadenosine, an alternative fluorescent nucleoside analog to 2'-deoxyribosyl-2-aminopurine with improved properties Journal Article

In: Nucleic Acids Res, vol. 33, no. 3, pp. 1031-1039, 2005, ISBN: 15718302, (1362-4962 Journal Article).

Abstract | Links | BibTeX | Tags: ENNIFAR, MARQUET, PAILLART, Unité ARN

2004

Schiltz M, Dumas P, Ennifar E, Flensburg C, Paciorek W, Vonrhein C, Bricogne G

Phasing in the presence of severe site-specific radiation damage through dose-dependent modelling of heavy atoms Journal Article

In: Acta Crystallogr D Biol Crystallogr, vol. 60, no. Pt 6, pp. 1024-1031, 2004, ISBN: 15159561, (0907-4449 Journal Article).

Abstract | Links | BibTeX | Tags: DUMAS, ENNIFAR, Unité ARN

Ehresmann C, Ehresmann B, Ennifar E, Dumas P, Garber M, Mathy N, Nikulin A, Portier C, Patel D, Serganov A

Molecular mimicry in translational regulation: the case of ribosomal protein S15. Journal Article

In: RNA Biol, vol. 1, no. 1, pp. 66-73, 2004, ISBN: 17194931, (Epub 2004 May 5.).

Abstract | Links | BibTeX | Tags: DUMAS, ENNIFAR, Unité ARN

2003

Ennifar E, Walter P, Dumas P

A crystallographic study of the binding of 13 metal ions to two related RNA duplexes Journal Article

In: Nucleic Acids Res, vol. 31, no. 10, pp. 2671-2682, 2003, ISBN: 12736317, (1362-4962 Journal Article).

Abstract | Links | BibTeX | Tags: Base Sequence Binding Sites/genetics Binding, Competitive Cations, Divalent/chemistry/metabolism Cobalt/chemistry/metabolism Comparative Study Crystallization Crystallography, ENNIFAR, Molecular Nucleic Acid Heteroduplexes/*chemistry/genetics/metabolism Oligoribonucleotides/chemistry/genetics/metabolism Platinum Compounds/chemistry/metabolism RNA/*chemistry/genetics/metabolism Ruthenium Compounds/chemistry/metabolism Support, Non-U.S. Gov't, Unité ARN, X-Ray Gold Compounds/chemistry/metabolism Magnesium/chemistry/metabolism Metals/*chemistry/metabolism Models

Ennifar E, Paillart J C, Marquet R, Ehresmann B, Ehresmann C, Dumas P, Walter P

HIV-1 RNA dimerization initiation site is structurally similar to the ribosomal A site and binds aminoglycoside antibiotics Journal Article

In: J Biol Chem, vol. 278, no. 4, pp. 2723-2730, 2003, ISBN: 12435744, (0021-9258 Journal Article).

Abstract | Links | BibTeX | Tags: Anti-Bacterial Agents/*pharmacology Binding Sites Dimerization HIV-1/*metabolism Models, ENNIFAR, MARQUET, Molecular Neomycin/pharmacology Nucleic Acid Conformation Paromomycin/pharmacology Protein Binding RNA/metabolism *RNA, Non-U.S. Gov't Temperature Ultraviolet Rays, PAILLART, Unité ARN, Viral Ribosomes/*metabolism Support

2002

Ennifar E, Carpentier P, Ferrer J L, Walter P, Dumas P

X-ray-induced debromination of nucleic acids at the Br K absorption edge and implications for MAD phasing Journal Article

In: Acta Crystallogr D Biol Crystallogr, vol. 58, no. Pt 8, pp. 1262-1268, 2002, ISBN: 12136136, (0907-4449 Journal Article).

Abstract | Links | BibTeX | Tags: Bromine/chemistry/radiation effects Crystallography, ENNIFAR, Non-U.S. Gov't X-Rays, Unité ARN, Viral/chemistry Support, X-Ray HIV-1/chemistry Molecular Structure Nucleic Acids/*chemistry/radiation effects RNA

Serganov A, Ennifar E, Portier C, Ehresmann B, Ehresmann C

Do mRNA and rRNA binding sites of E.coli ribosomal protein S15 share common structural determinants? Journal Article

In: J Mol Biol, vol. 320, no. 5, pp. 963-978, 2002, ISBN: 12126618, (0022-2836 Journal Article).

Abstract | Links | BibTeX | Tags: Binding Sites Cytosine Escherichia coli Guanosine Models, ENNIFAR, Messenger/*chemistry RNA, Molecular Nucleic Acid Conformation Protein Structure, Non-U.S. Gov't Uridine, Ribosomal/*chemistry Ribosomal Proteins/*chemistry Support, Tertiary RNA, Unité ARN

2001

Serganov A, Benard L, Portier C, Ennifar E, Garber M, Ehresmann B, Ehresmann C

Role of conserved nucleotides in building the 16 S rRNA binding site for ribosomal protein S15 Journal Article

In: J Mol Biol, vol. 305, no. 4, pp. 785-803, 2001, ISBN: 11162092, (0022-2836 Journal Article).

Abstract | Links | BibTeX | Tags: 16S/chemistry/*genetics/*metabolism RNA-Binding Proteins/chemistry/metabolism Ribosomal Proteins/chemistry/*metabolism Sequence Alignment Support, Amino Acid Sequence Base Pairing Base Sequence Binding Sites Conserved Sequence/*genetics *Escherichia coli/chemistry/genetics/metabolism Models, ENNIFAR, Molecular Molecular Sequence Data Mutation/genetics Nuclease Protection Assays Phylogeny Protein Binding Protein Conformation Purines/metabolism RNA, Non-U.S. Gov't Thermodynamics Thermus thermophilus/chemistry, Ribosomal, Unité ARN

2000

Nikulin A, Serganov A, Ennifar E, Tishchenko S, Nevskaya N, Shepard W, Portier C, Garber M, Ehresmann B, Ehresmann C, Nikonov S, Dumas P

Crystal structure of the S15-rRNA complex Journal Article

In: Nat Struct Biol, vol. 7, no. 4, pp. 273-277, 2000, ISBN: 10742169, (1072-8368 Journal Article).

Abstract | Links | BibTeX | Tags: 16S/*chemistry/genetics/*metabolism Ribosomal Proteins/*chemistry/*metabolism Structure-Activity Relationship Support, Amino Acid Sequence Base Pairing/drug effects/genetics Base Sequence Binding Sites/drug effects Conserved Sequence/genetics Crystallography, Bacterial/chemistry/genetics/metabolism RNA, ENNIFAR, Molecular Molecular Sequence Data *Nucleic Acid Conformation/drug effects Protein Conformation RNA, Non-U.S. Gov't Thermus thermophilus/*chemistry/genetics, Ribosomal, Unité ARN, X-Ray Magnesium/pharmacology Models

Ennifar E, Nikulin A, Tishchenko S, Serganov A, Nevskaya N, Garber M, Ehresmann B, Ehresmann C, Nikonov S, Dumas P

The crystal structure of UUCG tetraloop Journal Article

In: J Mol Biol, vol. 304, no. 1, pp. 35-42, 2000, ISBN: 11071808, (0022-2836 Journal Article).

Abstract | Links | BibTeX | Tags: 16S/*chemistry/genetics/*metabolism Ribosomal Proteins/chemistry/*metabolism Solvents Support, Base Sequence Crystallography, Biomolecular *Nucleic Acid Conformation RNA Stability RNA, ENNIFAR, Molecular Molecular Sequence Data Motion Nuclear Magnetic Resonance, Non-U.S. Gov't Thermodynamics, Ribosomal, Unité ARN, X-Ray Hydrogen Bonding Models

1999

Dumas P, Ennifar E, Walter P

Detection and treatment of twinning: an improvement and new results Journal Article

In: Acta Crystallogr D Biol Crystallogr, vol. 55, no. Pt 6, pp. 1179-87, 1999, ISBN: 10329781, (0907-4449 Journal Article).

Abstract | Links | BibTeX | Tags: ENNIFAR, HIV-1/*genetics *Nucleic Acid Conformation RNA, Unité ARN, Viral/*chemistry

Ennifar E, Yusupov M, Walter P, Marquet R, Ehresmann B, Ehresmann C, Dumas P

The crystal structure of the dimerization initiation site of genomic HIV-1 RNA reveals an extended duplex with two adenine bulges Journal Article

In: Structure, vol. 7, no. 11, pp. 1439-49, 1999, ISBN: 10574792, (0969-2126 Journal Article).

Abstract | Links | BibTeX | Tags: Adenine/*chemistry Base Pair Mismatch Base Sequence Crystallography, ENNIFAR, Molecular Molecular Sequence Data *Nucleic Acid Conformation RNA, Non-U.S. Gov't, Unité ARN, Viral/*chemistry/metabolism Support, X-Ray Dimerization HIV-1/*genetics Magnesium/metabolism Magnetic Resonance Spectroscopy Manganese/metabolism Models

123 entries « 3 of 3 »