RNA interference and receptors

@article{servant_graphene_2014,

title = {Graphene for multi-functional synthetic biology: the last 'zeitgeist' in nanomedicine},

author = {A Servant and A Bianco and M Prato and K Kostarelos},

doi = {10.1016/j.bmcl.2014.01.051},

issn = {1464-3405},

year  = {2014},

date = {2014-01-01},

journal = {Bioorganic & Medicinal Chemistry Letters},

volume = {24},

number = {7},

pages = {1638--1649},

abstract = {The high versatility of graphene has attracted significant attention in many areas of scientific research from electronics to physics and mechanics. One of the most intriguing utilisation of graphene remains however in nanomedicine and synthetic biology. In particular, the last decade has witnessed an exponential growth in the generation of novel candidate therapeutics of multiple biological activities based on graphene constructs with small molecules, such as anti-cancer drugs. In this Digest, we summarise the different synthetic strategies and routes available to fabricate these promising graphene conjugates and the opportunities for the design of multi-functional tools for synthetic biology that they offer.},

keywords = {Antineoplastic Agents, carbon, Drug delivery, Drug Design, Graphite, I2CT, Nanomaterials, Nanomedicine, nanotechnology, Synthetic Biology, Team-Bianco},

pubstate = {published},

tppubtype = {article}

}

@article{lacotte_interfacing_2008,

title = {Interfacing Functionalized Carbon Nanohorns with Primary Phagocytic Cells},

author = {Stéphanie Lacotte and Ainara García and Marion Décossas and Wafa' T Al‐Jamal and Shouping Li and Kostas Kostarelos and Sylviane Muller and Maurizio Prato and Hélène Dumortier and Alberto Bianco},

url = {https://onlinelibrary.wiley.com/doi/abs/10.1002/adma.200702753},

doi = {10.1002/adma.200702753},

issn = {1521-4095},

year  = {2008},

date = {2008-01-01},

urldate = {2020-03-31},

journal = {Advanced Materials},

volume = {20},

number = {12},

pages = {2421--2426},

abstract = {Functionalized carbon nanohorns (f-CNH) are uptaken by macrophages, without affecting cell viability. f-CNH induce the production of reactive oxygen species and of pro-inflammatory cytokines. The level of inflammation, although moderate, should be taken into consideration when using f-CNH for drug delivery. However, it could be exploited as an intrinsic f-CNH adjuvant function for biomedical applications requiring some activation of the immune system.},

keywords = {carbon nanostructures, Cells, Cytotoxicity, Drug delivery, I2CT, Team-Bianco},

pubstate = {published},

tppubtype = {article}

}

@article{lacerda_intracellular_2007,

title = {Intracellular Trafficking of Carbon Nanotubes by Confocal Laser Scanning Microscopy},

author = {L Lacerda and G Pastorin and D Gathercole and J Buddle and M Prato and A Bianco and K Kostarelos},

url = {https://onlinelibrary.wiley.com/doi/abs/10.1002/adma.200790051},

doi = {10.1002/adma.200790051},

issn = {1521-4095},

year  = {2007},

date = {2007-01-01},

urldate = {2020-03-31},

journal = {Advanced Materials},

volume = {19},

number = {14},

pages = {1789--1789},

keywords = {Biomedical materials, Cells, Drug delivery, fluorescence, I2CT, Nanotubes, single-walled, Team-Bianco},

pubstate = {published},

tppubtype = {article}

}

@article{campidelli_functionalization_2006,

title = {Functionalization of CNT: synthesis and applications in photovoltaics and biology},

author = {Stéphane Campidelli and Cédric Klumpp and Alberto Bianco and Dirk M Guldi and Maurizio Prato},

url = {https://onlinelibrary.wiley.com/doi/abs/10.1002/poc.1052},

doi = {10.1002/poc.1052},

issn = {1099-1395},

year  = {2006},

date = {2006-01-01},

urldate = {2020-03-31},

journal = {Journal of Physical Organic Chemistry},

volume = {19},

number = {8-9},

pages = {531--539},

abstract = {Here, we review part of the work carried out in our laboratories on carbon nanotube functionalization. Both covalent (sidewall derivatization) and non-covalent (using π-π interactions) functionalization have been used to solubilize carbon nanotubes (NTs). The combination of NTs with various electron donors, mainly using the supramolecular approach, led to a new generation of donor-acceptor nanohybrids which can be used for the development of carbon-based photovoltaic cells. Covalent functionalization has been successfully applied for preparation of water soluble nanotubes and further derivatization of the nanotubes with bioactive molecules hold great promise for application in drug, vaccine and gene delivery. Copyright © 2006 John Wiley & Sons, Ltd.},

keywords = {Carbon nanotubes, Cells, Drug delivery, electron transfer, Functionalization, I2CT, Peptides, photovoltaic, Team-Bianco, Toxicity, Vectors},

pubstate = {published},

tppubtype = {article}

}