Publications
2013
Ferrandon Dominique
The complementary facets of epithelial host defenses in the genetic model organism Drosophila melanogaster: from resistance to resilience Journal Article
In: Curr. Opin. Immunol., vol. 25, no. 1, pp. 59–70, 2013, ISSN: 1879-0372.
Abstract | Links | BibTeX | Tags: Adult Stem Cells, aging, Animal, Animals, Cell Proliferation, Disease Models, Enterocytes, ferrandon, Humans, Immunity, Intestinal Mucosa, M3i, Metagenome, Stem Cell Niche, Wound Healing
@article{ferrandon_complementary_2013b,
title = {The complementary facets of epithelial host defenses in the genetic model organism Drosophila melanogaster: from resistance to resilience},
author = {Dominique Ferrandon},
doi = {10.1016/j.coi.2012.11.008},
issn = {1879-0372},
year = {2013},
date = {2013-02-01},
journal = {Curr. Opin. Immunol.},
volume = {25},
number = {1},
pages = {59--70},
abstract = {Significant advances have been made in our understanding of the host defense against microbial infections taking place at frontier epithelia of Drosophila flies. Immune deficiency (IMD), the major NF-κB immune response pathway induced in these epithelia, displays remarkable adaptations in its activation and regulation in the respiratory and digestive tract. The host defense against ingested pathogens is not limited to resistance, that is, the immune response. It also involves resilience, the capacity of the host to endure and repair damages inflicted by pathogens or the host's own immune response. For instance, enterocytes damaged by pathogens, the microbiota of aging flies, or host-derived reactive oxygen species (ROS), are replaced under the control of multiple pathways by the compensatory proliferation of intestinal stem cells (ISCs).},
keywords = {Adult Stem Cells, aging, Animal, Animals, Cell Proliferation, Disease Models, Enterocytes, ferrandon, Humans, Immunity, Intestinal Mucosa, M3i, Metagenome, Stem Cell Niche, Wound Healing},
pubstate = {published},
tppubtype = {article}
}
1981
Lachaise F, Goudeau M, Hetru Charles, Kappler Christine, Hoffmann Jules A
Ecdysteroids and ovarian development in the shore crab, Carcinus maenas Journal Article
In: Hoppe-Seyler's Z. Physiol. Chem., vol. 362, no. 5, pp. 521–529, 1981, ISSN: 0018-4888.
Abstract | BibTeX | Tags: aging, Animals, Brachyura, Cross Reactions, Ecdysone, Ecdysterone, Female, hoffmann, M3i, Ovary, Radioimmunoassay, Sexual Maturation
@article{lachaise_ecdysteroids_1981,
title = {Ecdysteroids and ovarian development in the shore crab, Carcinus maenas},
author = {F Lachaise and M Goudeau and Charles Hetru and Christine Kappler and Jules A Hoffmann},
issn = {0018-4888},
year = {1981},
date = {1981-01-01},
journal = {Hoppe-Seyler's Z. Physiol. Chem.},
volume = {362},
number = {5},
pages = {521--529},
abstract = {Mature ovaries of the shore crab Carcinus maenas contain large concentrations of three major ecdysteroids which we have identified by physicochemical methods as ecdysone, 20-hydroxyecdysone and ponasterone A. The fluctuations of ovarian and blood ecdysteroid concentrations are presented in relation to the various stages of ovarian development.},
keywords = {aging, Animals, Brachyura, Cross Reactions, Ecdysone, Ecdysterone, Female, hoffmann, M3i, Ovary, Radioimmunoassay, Sexual Maturation},
pubstate = {published},
tppubtype = {article}
}