RNA interference and receptors

@article{chtarbanova_microbial_2011,

title = {Microbial sensing by Toll receptors: a historical perspective},

author = {Stanislava Chtarbanova and Jean-Luc Imler},

doi = {10.1161/ATVBAHA.108.179523},

issn = {1524-4636},

year  = {2011},

date = {2011-08-01},

journal = {Arteriosclerosis, Thrombosis, and Vascular Biology},

volume = {31},

number = {8},

pages = {1734--1738},

abstract = {The family of Toll-like receptors plays an essential role in the induction of the immune response. These receptors sense the presence of microbial ligands and activate the nuclear factor-κB transcription factor. We review the key studies that led from the formulation of the concept of pattern recognition receptors to the characterization of Toll-like receptors, insisting on the important role played by the model organism Drosophila melanogaster and on the increasing evidence connecting these receptors to cardiovascular disease.},

keywords = {Animals, Cardiovascular Diseases, history, Host-Pathogen Interactions, Humans, imler, Immunity, Innate, M3i, Macrophages, Toll-Like Receptors},

pubstate = {published},

tppubtype = {article}

}