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57 entries « 1 of 2 »


Huang Jianqiong, Lou Yanyan, Liu Jiyong, Bulet Philippe, Cai Chuping, Ma Kaiyu, Jiao Renjie, Hoffmann Jules A, Liégeois Samuel, Lia Zi, Ferrandon Dominique

A Toll pathway effector protects Drosophila specifically from distinct toxins secreted by a fungus or a bacterium Journal Article

In: PNAS, vol. 120, no. 12, 2023.

Abstract | Links | BibTeX | Tags: Baramicin A, Destruxin A, disease tolerance, enterocin O16, ferrandon, hoffmann, M3i, microbial toxins, resilience


Xu Rui, Lou Yanyan, Tidu Antonin, Bulet Philippe, Heinekamp Thorsten, Martin Franck, Brakhage Axel, Li Zi, Liégeois Samuel, Ferrandon Dominique

The Toll pathway mediates Drosophila resilience to Aspergillus mycotoxins through specific Bomanins Journal Article

In: EMBO Rep, pp. e56036, 2022, ISSN: 1469-3178.

Abstract | Links | BibTeX | Tags: ERIANI, ferrandon, M3i, MARTIN, Unité ARN


Liégeois Samuel, Ferrandon Dominique

An atlas for hemocytes in an insect Journal Article

In: Elife, 2020.

Abstract | Links | BibTeX | Tags: Drosophila, ferrandon, Hemocytes, M3i, single-cell

Liégeois Samuel, Wang Wenhui, Ferrandon Dominique

Methods to Quantify In Vivo Phagocytic Uptake and Opsonization of Live or Killed Microbes in Drosophila melanogaster Book Chapter

In: Handbooks, Springer Protocols (Ed.): Chapter 5, pp. 79, Springer Protocols Handbooks, 2020, ISBN: 9781071602584.

Abstract | Links | BibTeX | Tags: Drosophila, ferrandon, M3i, opsonization, Phagocytosis, protocol


Franchet Adrien, Niehus Sebastian, Caravello Gaetan, Ferrandon Dominique

Phosphatidic acid as a limiting host metabolite for the proliferation of the microsporidium Tubulinosema ratisbonensis in Drosophila flies Journal Article

In: Nature Microbiology, vol. 4, no. 4, pp. 645, 2019, ISBN: 2058-5276.

Abstract | Links | BibTeX | Tags: Drosophila, ferrandon, Host-Parasite Interactions, Lipids, M3i, metabolism, microsporidia


Gros Frédéric, Fournel Sylvie, Liégeois Samuel, Richard Daniel, Soulas-Sprauel Pauline

Atlas d'immunologie Book

Editions Dunod, 2018, ISBN: 9782100767052.

Abstract | BibTeX | Tags: atlas, cours, ferrandon, immunologie, M3i

Haller Samantha, Franchet Adrien, Hakkim A, Chen J, Drenkard E, Yu S, Schirmeier Steffi, Li Zi, Martins Nelson, Ausubel FM, Liégeois Samuel, Ferrandon Dominique

Quorum-sensing regulator RhlR but not its autoinducer RhlI enables Pseudomonas to evade opsonization Journal Article

In: EMBO Reports, 2018.

Links | BibTeX | Tags: Drosophila, ferrandon, M3i, Opsonin Proteins, Phagocytosis, Pseudomonas aeruginosa, Quorum Sensing


Lee Kwang-Zin, Lestradet Matthieu, Socha Catherine, Schirmeier Stefanie, Schmitz Antonin, Spenlé Caroline, Lefebvre Olivier, Keime Céline, Yamba Wennida M., Bou Aoun Richard, Liegeois Samuel, Schwab Yannick, Simon-Assmann Patricia, Dalle Frédéric, Ferrandon Dominique

Enterocyte Purge and Rapid Recovery Is a Resilience Reaction of the Gut Epithelium to Pore-Forming Toxin Attack Journal Article

In: Cell Host & Microbe, 2016, ISSN: 1931-3128.

Abstract | Links | BibTeX | Tags: Epithelium, ferrandon, gut, M3i, resilience


Brunke Sascha, Quintin Jessica, Kasper Lydia, Jacobsen Ilse D, Richter Martin E, Hiller Ekkehard, Schwarzmüller Tobias, d'Enfert Christophe, Kuchler Karl, Rupp Steffen, Hube Bernhard, Ferrandon Dominique

Of mice, flies--and men? Comparing fungal infection models for large-scale screening efforts Journal Article

In: Dis Model Mech, vol. 8, no. 5, pp. 473–486, 2015, ISSN: 1754-8411.

Abstract | Links | BibTeX | Tags: Alternative infection models, Candida glabrata, ferrandon, Fungal virulence factors, M3i, Mutant library, Signature-tagged mutagenesis


Amcheslavsky Alla, Song Wei, Li Qi, Nie Yingchao, Bragatto Ivan, Ferrandon Dominique, Perrimon Norbert, Ip Tony Y

Enteroendocrine cells support intestinal stem-cell-mediated homeostasis in Drosophila Journal Article

In: Cell Rep, vol. 9, no. 1, pp. 32–39, 2014, ISSN: 2211-1247.

Abstract | Links | BibTeX | Tags: Animals, Cell Differentiation, Enterocytes, Enteroendocrine Cells, Female, ferrandon, Homeostasis, Intestines, M3i, Male, Stem Cells, Tachykinins

Haller Samantha, Limmer Stefanie, Ferrandon Dominique

Assessing Pseudomonas virulence with a nonmammalian host: Drosophila melanogaster Journal Article

In: Methods Mol. Biol., vol. 1149, pp. 723–740, 2014, ISSN: 1940-6029.

Abstract | Links | BibTeX | Tags: Animal, Animals, Antimicrobial Cationic Peptides, Biological Assay, Colony Count, Disease Models, ferrandon, Hemolymph, Host-Pathogen Interactions, M3i, Mammals, Microbial, Pseudomonas aeruginosa, Pseudomonas Infections, Reverse Transcriptase Polymerase Chain Reaction, Virulence

Lestradet Matthieu, Lee Kwan Zin, Ferrandon Dominique

Drosophila as a model for intestinal infections Journal Article

In: Methods Mol Biol, vol. 1197, pp. 11–40, 2014, ISSN: 1940-6029 (Electronic) 1064-3745 (Linking).

Abstract | Links | BibTeX | Tags: Animal, Animals, Bacterial Physiological Phenomena, Disease Models, ferrandon, Gastrointestinal Tract, Host-Pathogen Interactions, M3i

Schwarzmüller Tobias, Ma Biao, Hiller Ekkehard, Istel Fabian, Tscherner Michael, Brunke Sascha, Ames Lauren, Firon Arnaud, Green Brian, Cabral Vitor, Marcet-Houben Marina, Jacobsen Ilse D, Quintin Jessica, Seider Katja, Frohner Ingrid, Glaser Walter, Jungwirth Helmut, Bachellier-Bassi Sophie, Chauvel Murielle, Zeidler Ute, Ferrandon Dominique, Gabaldón Toni, Hube Bernhard, d'Enfert Christophe, Rupp Steffen, Cormack Brendan, Haynes Ken, Kuchler Karl

Systematic phenotyping of a large-scale Candida glabrata deletion collection reveals novel antifungal tolerance genes Journal Article

In: PLoS Pathog., vol. 10, no. 6, pp. e1004211, 2014, ISSN: 1553-7374.

Abstract | Links | BibTeX | Tags: Antifungal Agents, Azoles, Biofilms, Candida glabrata, Candidiasis, Cell Wall, Drug Resistance, Echinocandins, ferrandon, Fungal, Fungal Proteins, Gene Deletion, Gene Knockout Techniques, Gene Library, M3i, Microbial Sensitivity Tests, Osmotic Pressure, Phenotype


Quintin Jessica, Asmar Joelle, Matskevich Alexey A, Lafarge Marie-Céline, Ferrandon Dominique

The Drosophila Toll pathway controls but does not clear Candida glabrata infections Journal Article

In: J. Immunol., vol. 190, no. 6, pp. 2818–2827, 2013, ISSN: 1550-6606.

Abstract | Links | BibTeX | Tags: Adaptor Proteins, Animal, Animals, Antigens, Candida glabrata, Candidiasis, Cells, Cultured, Differentiation, Disease Models, ferrandon, Immunologic, M3i, Phagocytosis, Receptors, Signal Transducing, Signal Transduction, Toll-Like Receptors, Virulence

Ferrandon Dominique

The complementary facets of epithelial host defenses in the genetic model organism Drosophila melanogaster: from resistance to resilience Journal Article

In: Curr. Opin. Immunol., vol. 25, no. 1, pp. 59–70, 2013, ISSN: 1879-0372.

Abstract | Links | BibTeX | Tags: Adult Stem Cells, aging, Animal, Animals, Cell Proliferation, Disease Models, Enterocytes, ferrandon, Humans, Immunity, Intestinal Mucosa, M3i, Metagenome, Stem Cell Niche, Wound Healing

Ayyaz Arshad, Giammarinaro Philippe, Liégeois Samuel, Lestradet Matthieu, Ferrandon Dominique

A negative role for MyD88 in the resistance to starvation as revealed in an intestinal infection of Drosophila melanogaster with the Gram-positive bacterium Staphylococcus xylosus Journal Article

In: Immunobiology, vol. 218, no. 4, pp. 635–644, 2013, ISSN: 1878-3279.

Abstract | Links | BibTeX | Tags: Adaptor Proteins, Animal, Animals, Antigens, Differentiation, Disease Models, ferrandon, Immunity, Immunologic, Innate, Intestinal Diseases, M3i, Mucosal, Mutation, Receptors, Signal Transducing, Staphylococcal Infections, Staphylococcus, Starvation, Toll-Like Receptors


Ezekowitz Alan R B, Dimarcq Jean-Luc, Kafatos Fotis, Levashina Elena A, Ferrandon Dominique, Hetru Charles, Imler Jean-Luc, Reichhart Jean-Marc

Lawrence's book review unfair to Hoffmann Journal Article

In: Curr. Biol., vol. 22, no. 12, pp. R482, 2012, ISSN: 1879-0445.

Links | BibTeX | Tags: Book Reviews as Topic, Ethics, ferrandon, imler, M3i, Professional, reichhart

Niehus Sebastian, Giammarinaro Philippe, Liégeois Samuel, Quintin Jessica, Ferrandon Dominique

Fly culture collapse disorder: detection, prophylaxis and eradication of the microsporidian parasite Tubulinosema ratisbonensis infecting Drosophila melanogaster Journal Article

In: Fly (Austin), vol. 6, no. 3, pp. 193–204, 2012, ISSN: 1933-6942.

Abstract | Links | BibTeX | Tags: Animals, Apansporoblastina, Apansporoblastina/*genetics/physiology, Base Sequence, cure, Disinfection, Disinfection/methods, DNA, DNA Primers, Drosophila melanogaster/*microbiology, ferrandon, fumagillin, Fungal, Fungal/chemistry, M3i, microsporidia, obligate intracellular parasitism, PCR detection, Phylogeny, Polymerase Chain Reaction, Polymerase Chain Reaction/methods, prophylaxis, Ribosomal, Ribosomal/chemistry, Sequence Alignment, Tubulinosema ratisbonensis

Meister Marie, Ferrandon Dominique

Immune cell transdifferentiation: a complex crosstalk between circulating immune cells and the haematopoietic niche Journal Article

In: EMBO Rep., vol. 13, no. 1, pp. 3–4, 2012, ISSN: 1469-3178.

Links | BibTeX | Tags: Animals, Cell Communication, Cell Transdifferentiation, ferrandon, Hematopoietic Stem Cells, Humans, Immune System, M3i, Signal Transduction, Stem Cell Niche


Imler Jean-Luc, Ferrandon Dominique

[Innate immunity crowned 2011 Nobel Prize winner] Journal Article

In: Med Sci (Paris), vol. 27, pp. 1019–24, 2011, ISSN: 0767-0974 (Print) 0767-0974 (Linking).

Links | BibTeX | Tags: *Immunity, *Nobel Prize, Biological, ferrandon, Genetic Association Studies, Humans, imler, Immunotherapy/methods/trends, Innate/genetics, M3i, Models, Molecular Targeted Therapy/trends, Seasons, Structure-Activity Relationship, Toll-Like Receptors/chemistry/genetics/isolation & purification/physiology

Limmer Stefanie, Haller Samantha, Drenkard Eliana, Lee Janice, Yu Shen, Kocks Christine, Ausubel Frederick M, Ferrandon Dominique

Pseudomonas aeruginosa RhlR is required to neutralize the cellular immune response in a Drosophila melanogaster oral infection model Journal Article

In: Proc. Natl. Acad. Sci. U.S.A., vol. 108, no. 42, pp. 17378–17383, 2011, ISSN: 1091-6490.

Abstract | Links | BibTeX | Tags: Animal, Animals, Bacteremia, Bacterial Proteins, Cellular, Disease Models, ferrandon, Genes, Genetically Modified, Hemolymph, Host-Pathogen Interactions, Immunity, Insect, M3i, Mutation, Oral, Pseudomonas aeruginosa, Pseudomonas Infections, Quorum Sensing, Trans-Activators, Viral, Virulence

Limmer Stefanie, Quintin Jessica, Hetru Charles, Ferrandon Dominique

Virulence on the fly: Drosophila melanogaster as a model genetic organism to decipher host-pathogen interactions Journal Article

In: Curr Drug Targets, vol. 12, no. 7, pp. 978–999, 2011, ISSN: 1873-5592.

Abstract | BibTeX | Tags: Animal, Animals, Anti-Infective Agents, Disease Models, Drug Delivery Systems, Drug Design, Drug Resistance, ferrandon, Fungi, High-Throughput Screening Assays, Host-Pathogen Interactions, Humans, M3i, Microbial, Pseudomonas aeruginosa

Aoun Richard Bou, Hetru Charles, Troxler Laurent, Doucet Daniel, Ferrandon Dominique, Matt Nicolas

Analysis of thioester-containing proteins during the innate immune response of Drosophila melanogaster Journal Article

In: J Innate Immun, vol. 3, no. 1, pp. 52–64, 2011, ISSN: 1662-8128.

Abstract | Links | BibTeX | Tags: Animals, bioinformatic, DNA, Evolution, ferrandon, Gene Expression Regulation, Hemocytes, Immunity, In Situ Hybridization, Innate, M3i, matt, Molecular, Mutation, Phylogeny, Sequence Analysis

Meister Marie, Ferrandon Dominique

Immune cell transdifferentiation: a complex crosstalk between circulating immune cells and the haematopoietic niche Journal Article

In: EMBO Rep, vol. 13, pp. 3–4, 2011, ISSN: 1469-3178 (Electronic) 1469-221X (Linking).

Links | BibTeX | Tags: ferrandon, M3i

Lee Kwang-Zin, Ferrandon Dominique

Negative regulation of immune responses on the fly Journal Article

In: EMBO J., vol. 30, no. 6, pp. 988–990, 2011, ISSN: 1460-2075.

Links | BibTeX | Tags: *Gene Expression Regulation, *Homeostasis, Animals, bacteria, Bacteria/*immunology, Biological, Drosophila melanogaster/*immunology, Drosophila Proteins/biosynthesis/metabolism, ferrandon, Gene Expression Regulation, Homeostasis, M3i, Mitogen-Activated Protein Kinases, Mitogen-Activated Protein Kinases/metabolism, Models, NF-kappa B, NF-kappa B/metabolism, ras Proteins, ras Proteins/metabolism, Receptor Protein-Tyrosine Kinases, Receptor Protein-Tyrosine Kinases/metabolism

Nehme Nadine T, Quintin Jessica, Cho Ju Hyun, Lee Janice, Lafarge Marie-Céline, Kocks Christine, Ferrandon Dominique

Relative roles of the cellular and humoral responses in the Drosophila host defense against three gram-positive bacterial infections Journal Article

In: PLoS ONE, vol. 6, no. 3, pp. e14743, 2011, ISSN: 1932-6203.

Abstract | Links | BibTeX | Tags: Animals, Antimicrobial Cationic Peptides, Carrier Proteins, Cell Surface, Cellular, Enterococcus faecalis, ferrandon, Gram-Positive Bacteria, Gram-Positive Bacterial Infections, Host-Pathogen Interactions, Humoral, Immunity, Innate, M3i, Micrococcus luteus, Opsonin Proteins, Phagocytosis, Receptors, Signal Transduction, Solubility, Staphylococcus aureus


Matskevich Alexey A, Quintin Jessica, Ferrandon Dominique

The Drosophila PRR GNBP3 assembles effector complexes involved in antifungal defenses independently of its Toll-pathway activation function Journal Article

In: Eur. J. Immunol., vol. 40, no. 5, pp. 1244–1254, 2010, ISSN: 1521-4141.

Abstract | Links | BibTeX | Tags: Agglutination, Animals, Beauveria, Beauveria/immunology, Candida albicans, Candida albicans/immunology, Carrier Proteins, Carrier Proteins/*immunology/pharmacology, Drosophila melanogaster/*immunology/microbiology, Drosophila Proteins/*immunology/pharmacology/physiology, Enzyme Activation, ferrandon, Fungal, Fungi, Fungi/*immunology, Hemolymph, Hemolymph/immunology, M3i, Melanins, Melanins/*physiology, Monophenol Monooxygenase, Monophenol Monooxygenase/physiology, Multiprotein Complexes, Multiprotein Complexes/physiology, Recombinant Fusion Proteins, Recombinant Fusion Proteins/pharmacology, Serpins, Serpins/physiology, Spores, Toll-Like Receptors, Toll-Like Receptors/immunology

Pospisilik Andrew J, Schramek Daniel, Schnidar Harald, Cronin Shane J F, Nehme Nadine T, Zhang Xiaoyun, Knauf Claude, Cani Patrice D, Aumayr Karin, Todoric Jelena, Bayer Martina, Haschemi Arvand, Puviindran Vijitha, Tar Krisztina, Orthofer Michael, Neely Gregory G, Dietzl Georg, Manoukian Armen, Funovics Martin, Prager Gerhard, Wagner Oswald, Ferrandon Dominique, Aberger Fritz, Hui Chi-chung, Esterbauer Harald, Penninger Josef M

Drosophila genome-wide obesity screen reveals hedgehog as a determinant of brown versus white adipose cell fate Journal Article

In: Cell, vol. 140, no. 1, pp. 148–160, 2010, ISSN: 1097-4172.

Abstract | Links | BibTeX | Tags: Adipocytes, Adipogenesis, Animals, Brown, Brown/metabolism, Cyclic AMP, Cyclic AMP/metabolism, Drosophila Proteins/*metabolism, ferrandon, Glucocorticoids, Glucocorticoids/metabolism, Hedgehog Proteins, Hedgehog Proteins/*metabolism, Humans, Knockout, M3i, Mice, Muscle Cells, Muscle Cells/metabolism, Obesity, Obesity/*genetics, Repressor Proteins, Repressor Proteins/genetics, White, White/metabolism


Mishima Yumiko, Quintin Jessica, Aimanianda Vishukumar, Kellenberger Christine, Coste Franck, Clavaud Cecile, Hetru Charles, Hoffmann Jules A, Latgé Jean-Paul, Ferrandon Dominique, Roussel Alain

The N-terminal domain of Drosophila Gram-negative binding protein 3 (GNBP3) defines a novel family of fungal pattern recognition receptors Journal Article

In: J. Biol. Chem., vol. 284, no. 42, pp. 28687–28697, 2009, ISSN: 1083-351X.

Abstract | Links | BibTeX | Tags: Animals, beta-Glucans, Bombyx, Carrier Proteins, Crystallography, ferrandon, Fungal Proteins, Hemolymph, hoffmann, ligands, M3i, Molecular Conformation, Mutagenesis, Polysaccharides, Protein Structure, Secondary, Tertiary, X-Ray

Ferrandon Dominique

Host tolerance versus resistance and microbial virulence in the host-pathogen equation Journal Article

In: Cell Host Microbe, vol. 6, no. 3, pp. 203–205, 2009, ISSN: 1934-6069.

Abstract | Links | BibTeX | Tags: Animals, ferrandon, Host-Pathogen Interactions, Immune Tolerance, M3i, Salmonella typhimurium, Virulence

Cronin Shane J F, Nehme Nadine T, Limmer Stefanie, Liegeois Samuel, Pospisilik Andrew J, Schramek Daniel, Leibbrandt Andreas, de Simoes Ricardo Matos, Gruber Susanne, Puc Urszula, Ebersberger Ingo, Zoranovic Tamara, Neely Gregory G, von Haeseler Arndt, Ferrandon Dominique, Penninger Josef M

Genome-wide RNAi screen identifies genes involved in intestinal pathogenic bacterial infection Journal Article

In: Science, vol. 325, no. 5938, pp. 340–343, 2009, ISSN: 1095-9203.

Abstract | Links | BibTeX | Tags: *Genome, *RNA Interference, Animal, Animals, Cell Proliferation, Drosophila melanogaster/*genetics/immunology/*microbiology, Drosophila Proteins/genetics/metabolism, Epithelial Cells, Epithelial Cells/cytology/physiology, ferrandon, Genetically Modified, Genome, Hemocytes, Hemocytes/immunology/metabolism/microbiology, Homeostasis, Immunity, Innate, Innate/*genetics, Insect, Intestinal Mucosa, Intestinal Mucosa/cytology/immunology/metabolism/microbiology, Janus Kinases, Janus Kinases/genetics/metabolism, M3i, Models, RNA Interference, Serratia Infections, Serratia Infections/genetics/*immunology/microbiology, Serratia marcescens, Serratia marcescens/*immunology/physiology, Signal Transduction, STAT Transcription Factors, STAT Transcription Factors/genetics/metabolism, Stem Cells, Stem Cells/cytology/physiology