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257 entries « 1 of 6 »

2023

H Cai, L Li, KM Slavik, J Huang, T Yin, X Ai, L Hédelin, G Haas, Z Xiang, Y Yang, X Li, Y Chen, Z Wei, H Deng, D Chen, R Jiao, N Martins, C Meignin, PJ Kranzusch, JL Imler

The virus-induced cyclic dinucleotide 2'3'-c-di-GMP mediates STING-dependent antiviral immunity in Drosophila Journal Article

In: Immunity, vol. 56, iss. 9, pp. 1991-2005, 2023.

Abstract | Links | BibTeX | Tags: c-di-GMP, cGAMP, cGAS, cGLR, cyclic dinucleotide, Drosophila, Evolution, Hua, imler, M3i, meignin, pattern recognition receptor, STING, virus

de Faria Isaque J. S., Imler Jean-Luc, Marques João T.

Protocol for the analysis of double-stranded RNAs in virus-infected insect cells using anti-dsRNA antibodies Journal Article

In: STAR Protocols, vol. 4, iss. 1, 2023.

Abstract | Links | BibTeX | Tags: antibody, cell bioloby, imler, Immunology, M3i, Marques, microbiology, Microscopy, Molecular Biology

Huang Jianqiong, Lou Yanyan, Liu Jiyong, Bulet Philippe, Cai Chuping, Ma Kaiyu, Jiao Renjie, Hoffmann Jules A, Liégeois Samuel, Lia Zi, Ferrandon Dominique

A Toll pathway effector protects Drosophila specifically from distinct toxins secreted by a fungus or a bacterium Journal Article

In: PNAS, vol. 120, no. 12, 2023.

Abstract | Links | BibTeX | Tags: Baramicin A, Destruxin A, disease tolerance, enterocin O16, ferrandon, hoffmann, M3i, microbial toxins, resilience

R.P. Olmo, Y.M.H. Todjro, E.R.G.R. Aguiar, de Almeida J.P.P., F.V. Ferreira, J.N. Armache, de Faria I.J.S., A.G.A. Ferreira, S.C.D. Amadou, A.T.S. Silva, de Souza K.P.R., A.P.P. Vilela, A. Babarit, C.H. Tan, M. Diallo, A. Gaye, C. Paupy, J. Obame-Nkoghe, T.M. Visser, C.J.M. Koenraadt, M.A. Wongsokarijo, A.L.C. Cruz, M.T. Prieto, M.C.P. Parra, Nogueira M.L., V. Avelino-Silva, R.N. Mota, M.A.Z. Borges, B.P. Drumond, E.G. Kroon, M. Recker, L. Sedda, E. Marois, J.L. Imler, J.T. Marques

Mosquito vector competence for dengue is modulated by insect-specific viruses Journal Article

In: Nature Microbiology, vol. 8, iss. 1, 2023.

Abstract | Links | BibTeX | Tags: Dengue, imler, M3i, marois, Marques, mosquito, Olmo, virus

2022

de Faria Isaque J. S., Aguiar Eric R. G. R., Olmo Roenick P., da Silva Juliana Alves, Daeffler Laurent, Carthew Richard W., Imler Jean-Luc, Marques Joao T.

Invading viral DNA triggers dsRNA synthesis by RNA polymerase II to activate antiviral RNA interference in Drosophila Journal Article

In: Cell Reports, vol. 39, pp. 110976, 2022.

Abstract | Links | BibTeX | Tags: antiviral, Drosophila, dsRNA, imler, M3i, Marques, protocol, RNA Interference

Cai H, Meignin C, Imler JL

cGAS-like receptor-mediated immunity: the insect perspective Journal Article

In: Current Opinion in Immunology, vol. 74, pp. 183-189, 2022.

Abstract | Links | BibTeX | Tags: imler, M3i, meignin

2021

Pennemann Friederike L, Mussabekova Assel, Urban Christian, Stukalov Alexey, Andersen Line Lykke, Grass Vincent, Lavacca Teresa Maria, Holze Cathleen, Oubraham Lila, Benamrouche Yasmine, Girardi Enrico, Boulos Rasha E, Hartmann Rune, Superti-Furga Giulio, Habjan Matthias, Imler Jean-Luc, Meignin Carine, Pichlmair Andreas

Cross-species analysis of viral nucleic acid interacting proteins identifies TAOKs as innate immune regulators Journal Article

In: Nat Commun, vol. 12, no. 1, pp. 7009, 2021, ISSN: 2041-1723.

Abstract | Links | BibTeX | Tags: antiviral innate immunity, imler, M3i, meignin

Loiseau Vincent, Peccoud Jean, Bouzar Clémence, Guillier Sandra, Fan Jiangbin, Alletti Gianpiero Gueli, Meignin Carine, Herniou Elisabeth A, Federici Brian A, Wennmann Jörg T, Jehle Johannes A, Cordaux Richard, Gilbert Clément

Monitoring Insect Transposable Elements in Large Double-Stranded DNA Viruses Reveals Host-to-Virus and Virus-to-Virus Transposition Journal Article

In: Mol Biol Evol, vol. 38, no. 9, pp. 3512–3530, 2021, ISSN: 1537-1719.

Abstract | Links | BibTeX | Tags: M3i, meignin

Prakash Pragya, Roychowdhury-Sinha Arghyashree, Goto Akira

Verloren negatively regulates the expression of IMD pathway dependent antimicrobial peptides in Drosophila Journal Article

In: Scientific Reports, vol. 11, no. 15549, 2021.

Abstract | Links | BibTeX | Tags: bacteria, Biochemistry, DNA, Fungi, Gene Expression, gene regulation, Genetics, hoffmann, Immunochemistry, Immunology, infection, inflammation, Innate immune cells, innate immunity, M3i, microbiology, Molecular Biology, pathogens, RNA, RNAi, Signal Transduction, Transcription

Holleufer Andreas, Winther Kasper Grønbjerg, Gad Hans Henrik, Ai Xianlong, Chen Yuqiang, Li Lihua, Wei Ziming, Deng Huimin, Liu Jiyong, Frederiksen Ninna Ahlmann, Simonsen Bine, Andersen Line Lykke, Kleigrewe Karin, Dalskov Louise, Pichlmair Andreas, Cai Hua, Imler Jean-Luc, Hartmann Rune

Two cGAS-like receptors induce antiviral immunity in Drosophila Journal Article

In: Nature, vol. 597, pp. 114-118, 2021.

Abstract | Links | BibTeX | Tags: antiviral immunity, cGAS-like receptors, Drosophila, imler, M3i

Slavik Kailey M, Morehouse Benjamin R, Ragucci Adelyn E, Zhou Wen, Ai Xianlong, Chen Yuqiang, Li Lihua, Wei Ziming, Bähre Heike, König Martin, Seifert Roland, Lee Amy S Y, Cai Hua, Imler Jean-Luc, Kranzusch Philip J

cGAS-like receptors sense RNA and control 3'2'-cGAMP signalling in Drosophila Journal Article

In: Nature, vol. 597, no. 7874, pp. 109–113, 2021, ISSN: 1476-4687.

Abstract | Links | BibTeX | Tags: imler, M3i

Cai Hua, Imler Jean-Luc

cGAS-STING: insight on the evolution of a primordial antiviral signaling cassette Journal Article

In: Faculty Reviews, vol. 10, pp. 54, 2021.

Abstract | Links | BibTeX | Tags: imler, M3i

Leite Thiago H J F, Ferreira Alvaro G A, Imler Jean-Luc, Marques João T

Distinct Roles of Hemocytes at Different Stages of Infection by Dengue and Zika Viruses in Aedes aegypti Mosquitoes Journal Article

In: Frontiers in immunology, vol. 12, pp. 660873, 2021.

Abstract | Links | BibTeX | Tags: Aedes, Dengue, Hemocytes, imler, innate immunity, M3i, Marques, Zika

Chen Di, Roychowdhury-Sinha Arghyashree, Prakash Pragya, Lan Xiao, Fan Wenmin, Goto Akira, Hoffmann Jules A

A time course transcriptomic analysis of host and injected oncogenic cells reveals new aspects of Drosophila immune defenses Journal Article

In: PNAS, vol. 118, no. 12, 2021.

Abstract | Links | BibTeX | Tags: cancer, chemoreceptor, Drosophila melanogaster, goto, hoffmann, innate immunity, M3i, RasV12

Jactel H, Imler JL, Lambrechts L, Failloux AB, Lebreton JD, Maho Y Le, Duplessy JC, Cossart P, Grandcolas P

Insect decline: immediate action is needed Journal Article

In: Comptes Rendus. Biologies, 2021, ISSN: 17683238.

Abstract | Links | BibTeX | Tags: imler, M3i

2020

Schneider J, Imler JL

Sensing and signalling viral infection in drosophila Journal Article

In: Developmental and Comparative Immunology, vol. 117, 2020.

Abstract | Links | BibTeX | Tags: imler, M3i

Rousseau C, Meignin C

[Viral sensing by RNA helicases] Journal Article

In: Virologie (Montrouge), vol. 24, no. 6, pp. 419-436, 2020, ISBN: 1267-8694.

Links | BibTeX | Tags: antiviral innate immunity, M3i, meignin

Rousseau C, Meignin C

Viral sensing by RNA helicases Journal Article

In: Virologie (Montrouge), vol. 24, no. 6, pp. 36-52, 2020, ISSN: 1267-8694.

Links | BibTeX | Tags: antiviral innate immunity, M3i, meignin

Cai H, Holleufer A, Simonsen B, Schneider J, Lemoine A, Gad HH, Huang J, Huang J, Chen D, Peng T, Marques JT, Hartmann R, Martins N, Imler JL

2'3'-cGAMP triggers a STING- and NF-κB-dependent broad antiviral response in Drosophila Journal Article

In: Science Signaling, vol. 13, no. 660, pp. eabc4537, 2020.

Abstract | Links | BibTeX | Tags: imler, M3i, Marques, STING

Imler JL, Hofmann JA

L'immunité innée Book Chapter

In: Cramer, P; Meignien, A (Ed.): vol. Le défi des maladies infectieuses, pp. 191-203, Les éditions du Palais, Docis, 2020, ISBN: 9791090119895.

BibTeX | Tags: hoffmann, imler, M3i

Aguiar ERGR, de Almeida JPP, Queiroz LR, Oliveira LS, Olmo RP, de Faria IJDS, Imler JL, Gruber A, Matthews BJ, Marques JT

A single unidirectional piRNA cluster similar to the flamenco locus is the major source of EVE-derived transcription and small RNAs in Aedes aegypti mosquitoes Journal Article

In: RNA, vol. 26, no. 5, pp. 581-594, 2020.

Abstract | Links | BibTeX | Tags: A. aegypti, Aedes aegypti, endogenous viral elements, EVE, flamenco locus, imler, M3i, Marques, piRNA, piRNAs, RNA Interference

Goto Akira, Okado Kiyoshi, Martins Nelson, Cai Hua, Barbier Vincent, Lamiable Olivier, Troxler Laurent, Santiago Estelle, Kuhn Lauriane, Paik Donggi, Silverman Neal, Holleufer Andreas, Hartmann Rune, Liu Jiyong, Peng Tao, Hoffmann Jules A, Meignin Carine, Daeffler Laurent, Imler Jean-Luc

The Kinase IKKβ Regulates a STING-and NF-κB-Dependent Antiviral Response Pathway in Drosophila Journal Article

In: Immunity, vol. 52, no. 1, pp. 200, 2020.

Abstract | Links | BibTeX | Tags: antiviral, Drosophila, hoffmann, imler, Kinase, M3i, meignin, STING

Donelick H M, Talide L, Bellet M, Aruscavage P J, Lauret E, Aguiar E R G R, Marques J T, Meignin C, Bass B L

In vitro studies provide insight into effects of Đicer-2 helicase mutations in Đrosophila melanogaster Journal Article

In: RNA, vol. 26, no. 12, pp. 1847–1861, 2020, ([PubMed Central:hrefhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7668257PMC7668257] [DOI:hrefhttps://dx.doi.org/10.1261/rna.077289.12010.1261/rna.077289.120] [PubMed:hrefhttps://www.ncbi.nlm.nih.gov/pubmed/2136255421362554]).

BibTeX | Tags: antiviral innate immunity, Dicer-2, Drosophila melanogaster, M3i, meignin

Loiseau V, Herniou E A, Moreau Y, Lévêque N, Meignin C, Daeffler L, Federici B, Cordaux R, Gilbert C

Wide spectrum and high frequency of genomic structural variation, including transposable elements, in large double-stranded ĐNA viruses Journal Article

In: Virus Evol, vol. 6, no. 1, pp. vez060, 2020, ([PubMed Central:hrefhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6983493PMC6983493] [DOI:hrefhttps://dx.doi.org/10.1093/ve/vez06010.1093/ve/vez060] [PubMed:hrefhttps://www.ncbi.nlm.nih.gov/pubmed/2739260627392606]).

BibTeX | Tags: M3i, meignin, virus

2019

Talide L, Imler JL, Meignin C

Sensing Viral Infections in Insects: A Dearth of Pathway Receptors Journal Article

In: Curr Issues Mol Biol, vol. 34, pp. 31-60, 2019, ISBN: 9781912530090.

Abstract | Links | BibTeX | Tags: imler, innate immunity, M3i, meignin, STAT, viral Infection

Olmo RP, Martins NE, Aguiar ERGR, Marques JT, Imler JL

The insect reservoir of biodiversity for viruses and for antiviral mechanisms Journal Article

In: An Acad Bras Cienc , vol. 91, no. Suppl 3, pp. e20190122, 2019.

Abstract | Links | BibTeX | Tags: antiviral immunity, imler, insects, M3i, Marques, metagenomics, restriction factors, RNA Interference, virome

Einhorn E., Imler JL

Insect Immunity: From Systemic to Chemosensory Organs Protection Book Chapter

In: Picimbon, JF (Ed.): vol. 2, pp. 205-229, Springer, 2019, ISBN: 9783030051648.

Abstract | Links | BibTeX | Tags: imler, M3i

Martins NE, Olmo RP, Aguiar ERGR, Marques JT, Imler JL

Les insectes : un fantastique réservoir de virus et de gènes antiviraux Journal Article

In: Biologie Aujourd'hui, vol. 212, no. 3-4, pp. 101-106, 2019.

Abstract | Links | BibTeX | Tags: antiviral immunity, ARN interference, imler, Insect, M3i, Marques, metagenomic, virome

Martins N, Lemoine A, Santiago E, Paro S, Imler JL, Meignin C

A Transgenic Flock House Virus Replicon Reveals an RNAi Independent Antiviral Mechanism Acting in Drosophila Follicular Somatic Cells Journal Article

In: G3 (Bethesda), vol. 9, no. 2, pp. 403-412, 2019.

Links | BibTeX | Tags: antiviral immunity, Drosophila melanogaster, Follicular somatic cells, Genetics of Immunity, imler, M3i, meignin, replicon, Viral replicon

2018

Olmo RP, Ferreira AGA, Izidoro-Toledo TC, Aguiar ERGR, de Faria IJS, de Souza KPR, Osório KP, Kuhn L, Hammann P, de Andrade EG, Todjro YM, Rocha MN, Leite THJF, Amadou SCG, Armache JN, Paro S, de Oliveira CD, Carvalho FD, Moreira LA, Marois E, Imler JL, Marques JT

Control of dengue virus in the midgut of Aedes aegypti by ectopic expression of the dsRNA-binding protein Loqs2 Journal Article

In: Nature Microbiology, vol. 3, no. 12, pp. 1385-1393, 2018.

Abstract | Links | BibTeX | Tags: Aedes aegypti, Dengue, imler, M3i, marois, Marques, Zika

Goto Akira, Okado Kiyoshi, Martins Nelson, Cai Hua, Barbier Vincent, Lamiable Olivier, Troxler Laurent, Santiago Estelle, Kuhn Lauriane, Paik Donggi, Silverman Neal, Holleufer Andreas, Hartmann Rune, Liu Jiyong, Peng Tao, Hoffmann Jules A, Meignin Carine, Daeffler Laurent, Imler Jean-Luc

The Kinase IKKβ Regulates a STING- and NF-κB-Dependent Antiviral Response Pathway in Drosophila Journal Article

In: Immunity, no. 49, pp. 225-234, 2018.

Abstract | Links | BibTeX | Tags: hoffmann, imler, M3i, meignin, PPSE

Ferreira Flávia Viana, Aguiar Eric Roberto Guimarães Rocha, Olmo Roenick Proveti, de Oliveira Karla Pollyanna Vieira, Silva Emanuele Guimarães, Sant'Anna Maurício Roberto Viana, de Gontijo Nelder Figueiredo, Kroon Erna Geessien, Imler Jean-Luc, Marques João Trindade

The small non-coding RNA response to virus infection in the Leishmania vector Lutzomyia longipalpis Journal Article

In: PLoS Negl Trop Dis, vol. 12, no. 6, pp. e0006569, 2018, ISSN: 1935-2735.

Abstract | Links | BibTeX | Tags: Animals, Host-Pathogen Interactions, imler, Insect Vectors, Leishmania, M3i, ncRNA, Psychodidae, RNA, RNA Interference, Small Interfering, Untranslated, Vesicular stomatitis Indiana virus, Viral

2017

Kuhn Lauriane, Majzoub Karim, Einhorn Evelyne, Chicher Johana, Pompon Julien, Imler Jean-Luc, Hammann Philippe, Meignin Carine

Definition of a RACK1 Interaction Network in Drosophila melanogaster Using SWATH-MS Journal Article

In: G3 (Bethesda), 2017, ISSN: 2160-1836.

Abstract | Links | BibTeX | Tags: imler, M3i, meignin, PPSE

Gross E, Vincens Q, Einhorn E, Noireterre A, Schaeffer L, Kuhn L, Imler JL, Eriani, Meignin C, Martin F

The IRES5'UTR of the dicistrovirus cricket paralysis virus is a type III IRES containing an essential pseudoknot structure Journal Article

In: Nucleic Acids Research, vol. 45, no. 15, pp. 8993-9004, 2017.

Abstract | Links | BibTeX | Tags: imler, IRES, M3i, meignin

FM Cao C Cogni R Barbier V Jiggins

Complex Coding and Regulatory Polymorphisms in a Restriction Factor Determine the Susceptibility of Drosophila to Viral Infection Journal Article

In: Genetics, vol. 206, pp. 2159-2173, 2017.

Abstract | Links | BibTeX | Tags: imler, M3i

Gross L, Vicens Q, Einhorn E, Noireterre A, Schaeffer L, Kuhn L, Imler JL, Eriani G, Meignin C, Martin F

The IRES5'UTR of the dicistrovirus cricket paralysis virus is a type III IRES containing an essential pseudoknot structure Journal Article

In: Nucleic Acids Res, vol. 45, no. 15, pp. 8993-9004, 2017, ISBN: 28911115.

Abstract | Links | BibTeX | Tags: ERIANI, meignin, PPSE, Unité ARN

Gross Lauriane, Vicens Quentin, Einhorn Evelyne, Noireterre Audrey, Schaeffer Laure, Kuhn Lauriane, Imler Jean-Luc, Eriani Gilbert, Meignin Carine, Martin Franck

The IRES5'UTR of the dicistrovirus cricket paralysis virus is a type III IRES containing an essential pseudoknot structure Journal Article

In: Nucleic Acids Research, vol. 45, no. 15, pp. 8993–9004, 2017, ISSN: 1362-4962.

Abstract | Links | BibTeX | Tags: meignin, PPSE

Kuhn Lauriane, Majzoub Karim, Einhorn Evelyne, Chicher Johana, Pompon Julien, Imler Jean-Luc, Hammann Philippe, Meignin Carine

Definition of a RACK1 Interaction Network in Drosophila melanogaster Using SWATH-MS Journal Article

In: G3 (Bethesda), 2017, ISSN: 2160-1836.

Abstract | Links | BibTeX | Tags: meignin, PPSE