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2004

Costa A., de Barros J. P. Pais, Keith G., Baranowski W., Desgres J.

Determination of queuosine derivatives by reverse-phase liquid chromatography for the hypomodification study of Q-bearing tRNAs from various mammal liver cells Journal Article

In: J Chromatogr B Analyt Technol Biomed Life Sci, vol. 801, no. 2, pp. 237-47, 2004, (1570-0232 Journal Article).

Abstract | BibTeX | Tags: *Chromatography, &, Acyl/chemistry, Amino, Animals, Asn/chemistry, Cells, Chickens, Cultured, derivatives/*analysis, Experimental, Gov't, Hepatocytes/chemistry, high, KEITH, liquid, Liver, Liver/*chemistry, Neoplasms, Non-U.S., Nucleoside, Pressure, purification, Q/*analogs, Rats, RNA, Support, Transfer, Transfer/*chemistry/isolation, tumor

Delarue M., Dumas P.

On the use of low-frequency normal modes to enforce collective movements in refining macromolecular structural models Journal Article

In: Proc Natl Acad Sci U S A, vol. 101, no. 18, pp. 6957-62, 2004, (0027-8424 Journal Article).

Abstract | BibTeX | Tags: *Models, Carrier, coli, Computer, Diffraction, DUMAS, Escherichia, Gov't, Molecular, Non-U.S., Proteins/*chemistry, Proteins/chemistry, Simulation, Support, X-Ray

de la Pena-Lefebvre P. Garcia, Chanseaud Y., Tamby M. C., Reinbolt J., Batteux F., Allanore Y., Kahan A., Meyer O., Benveniste O., Boyer O., Guillevin L., Boissier M. C., Mouthon L.

IgG reactivity with a 100-kDa tissue and endothelial cell antigen identified as topoisomerase 1 distinguishes between limited and diffuse systemic sclerosis patients Journal Article

In: Clin Immunol, vol. 111, no. 3, pp. 241-51, 2004, (1521-6616 Journal Article).

Abstract | BibTeX | Tags: Aged, Assay, Autoantibodies/*analysis, Blotting, Cells/*immunology, Centromere/immunology, DNA, EHRESMANN, Electrophoresis, Endothelial, Enzyme-Linked, Female, G/analysis, Gel, Gov't, Human, I/*immunology, Immunoglobulin, Immunosorbent, M/analysis, Male, Middle, Non-U.S., Polyacrylamide, Scleroderma, Support, Systemic/*immunology, Topoisomerases, Type, Western

Grosjean H., Keith G., Droogmans L.

Detection and quantification of modified nucleotides in RNA using thin-layer chromatography Book Section

In: Gott, J. M. (Ed.): RNA Interference, Editing, and Modification: Methods and Protocols, vol. 265, pp. 357-91, Springer Protocols, Humana Press, 2004.

Abstract | BibTeX | Tags: &, 5', acids, and, Base, Chromatography, Composition, Deoxyribonucleotides/chemistry/isolation, DNA/chemistry/genetics/isolation, Endoribonucleases, Gov't, Indicators, Isotope, KEITH, Labeling/methods, Layer/methods, Non-U.S., Nucleic, Oligoribonucleotides/chemistry/isolation, Peptide, purification, Radioisotopes, Reagents, Regions/chemistry, Ribonucleotides/*analysis, RNA/*genetics/isolation, Support, Thin, Untranslated

Martineau Y., Bec C. Le, Monbrun L., Allo V., Chiu I. M., Danos O., Moine H., Prats H., Prats A. C.

Internal ribosome entry site structural motifs conserved among mammalian fibroblast growth factor 1 alternatively spliced mRNAs Journal Article

In: Mol Cell Biol, vol. 24, no. 17, pp. 7622-35, 2004, (0270-7306 Journal Article).

Abstract | BibTeX | Tags: (Genetics), *5', *Alternative, *Nucleic, *Promoter, 1/*genetics, Acid, Alignment, Animals, Base, Cell, Conformation, Data, EHRESMANN, Factor, Fibroblast, Gene, Genes, Genetic, Gov't, Growth, Human, Line, Messenger/chemistry/*genetics/metabolism, Mice, Molecular, Muscle, Mutagenesis, Non-U.S., Regions, Ribosomes/*metabolism, RNA, Sequence, Site-Directed, Skeletal/cytology/physiology, Splicing, Structural/genetics, Support, Techniques, Transfer, Untranslated, Vectors

Przykorska A., Solecka K., Olszak K., Keith G., Nawrot B., Kuligowska E.

Wheat (Triticum vulgare) chloroplast nuclease ChSI exhibits 5' flap structure-specific endonuclease activity Journal Article

In: Biochemistry, vol. 43, no. 35, pp. 11283-94, 2004, (0006-2960 Journal Article).

Abstract | BibTeX | Tags: &, Acid, Catalysis, Chloroplasts/*enzymology, Conformation, Desorption-Ionization, DNA, Endonucleases/*chemistry/isolation, Exonucleases/chemistry/metabolism, Flap, Gov't, Hydrolysis, KEITH, Kinetics, Laser, Mass, Matrix-Assisted, Non-U.S., Nucleic, Oligonucleotides/chemical, Plant/chemistry/metabolism, purification/*metabolism, Relationship, Single-Stranded/chemistry/metabolism, Specificity, Spectrometry, Structure-Activity, Substrate, Support, synthesis/metabolism, Thermodynamics, Triticum/*enzymology

Zukiel R., Nowak S., Barciszewska A. M., Gawronska I., Keith G., Barciszewska M. Z.

A simple epigenetic method for the diagnosis and classification of brain tumors Journal Article

In: Mol Cancer Res, vol. 2, no. 3, pp. 196-202, 2004, (1541-7786 Journal Article).

Abstract | BibTeX | Tags: *DNA, *Epigenesis, 5-Methylcytosine/*analysis, Adult, Aged, and, Brain, Chromatography, DNA, Female, Genetic, Gov't, Human, KEITH, Layer, Male, Methylation, Middle, Neoplasm/*chemistry/*metabolism, Neoplasms/*classification/*diagnosis/genetics/pathology, Non-U.S., Oxidative, oxygen, Reactive, Sensitivity, Species/metabolism, Specificity, Stress, Support, Thin

Ferrandon Dominique, Imler Jean-Luc, Hoffmann Jules A

Sensing infection in Drosophila: Toll and beyond Journal Article

In: Semin Immunol, vol. 16, pp. 43–53, 2004, ISSN: 1044-5323.

Abstract | BibTeX | Tags: Animals, Carrier Proteins/chemistry/immunology/physiology, Cell Surface/immunology/*physiology, Drosophila Proteins/chemistry/immunology/*physiology, Drosophila/genetics/*immunology/microbiology, ferrandon, Fungi/immunology, Gene Expression Regulation, Gram-Negative Bacterial Infections/immunology, Gram-Positive Bacterial Infections/immunology, hoffmann, imler, Immunological, Insect Proteins/chemistry/immunology/physiology, M3i, Models, Non-U.S. Gov't, Receptors, Signal Transduction/immunology/physiology, Support

2003

Kurz Léopold C, Chauvet Sophie, Andrès Emmanuel, Aurouze Marianne, Vallet Isabelle, Michel Gérard P F, Uh Mitch, Celli Jean, Filloux Alain, Bentzmann Sophie De, Steinmetz Ivo, Hoffmann Jules A, Finlay Brett B, Gorvel Jean-Pierre, Ferrandon Dominique, Ewbank Jonathan J

Virulence factors of the human opportunistic pathogen Serratia marcescens identified by in vivo screening Journal Article

In: Embo J, vol. 22, pp. 1451–60, 2003, ISBN: 0261-4189.

Abstract | Links | BibTeX | Tags: *Virulence, Animal, Caenorhabditis elegans/*microbiology, ferrandon, hoffmann, M3i, Mutation, Non-U.S. Gov't, Serratia marcescens/genetics/*pathogenicity, Support

Bonnal S., Schaeffer C., Creancier L., Clamens S., Moine H., Prats A. C., Vagner S.

A single internal ribosome entry site containing a G quartet RNA structure drives fibroblast growth factor 2 gene expression at four alternative translation initiation codons Journal Article

In: J Biol Chem, vol. 278, no. 41, pp. 39330-6, 2003, (0021-9258 Journal Article).

Abstract | BibTeX | Tags: 2/*genetics, Acid, Alternative, Base, Cell, Chain, Codon, Complementary/genetics, Conformation, Data, Deletion, DNA, Expression, Factor, Fibroblast, Gene, Gov't, Growth, Human, initiation, Initiator/genetics, Line, Messenger/*chemistry/*genetics, Molecular, Non-U.S., Nucleic, Peptide, Ribosomes/*metabolism, RNA, Sequence, Splicing, Support, Transfection

Heyman T., Wilhelm M., Wilhelm F. X.

The central PPT of the yeast retrotransposon Ty1 is not essential for transposition Journal Article

In: J Mol Biol, vol. 331, no. 2, pp. 315-20, 2003, (0022-2836 Journal Article).

Abstract | BibTeX | Tags: Base, cerevisiae/genetics, Data, DNA/*biosynthesis, Genetic, Gov't, Models, Molecular, Mutation, Non-U.S., Purines/*chemistry, Retroelements/*genetics, Saccharomyces, Sequence, Support

Miturski R., Postawski K., Semczuk A., Bogusiewicz M., Baranowski W., Jakowicki J. A., Keith G.

Global DNA methylation in relation to hMLH1 and hMSH2 protein immunoreactivity in sporadic human endometrial carcinomas Journal Article

In: Int J Mol Med, vol. 11, no. 5, pp. 569-74, 2003, (1107-3756 Journal Article).

Abstract | BibTeX | Tags: *DNA, Base, Carcinoma/genetics/*metabolism/pathology, DNA, Endometrial, Female, Gov't, Human, Immunohistochemistry, Methylation, Mismatch, Neoplasm, Neoplasms/genetics/*metabolism/pathology, Non-U.S., Pair, Proteins/*metabolism, Proto-Oncogene, Repair, Support

Wilhelm F. X., Wilhelm M., Gabriel A.

Extension and cleavage of the polypurine tract plus-strand primer by Ty1 reverse transcriptase Journal Article

In: J Biol Chem, vol. 278, no. 48, pp. 47678-84, 2003, (0021-9258 Journal Article).

Abstract | BibTeX | Tags: Base, Calf, Data, DNA, DNA/chemistry, Genetic, Gov't, H, Messenger/metabolism, Models, Molecular, Non-U.S., P.H.S., Polymerase/*chemistry, Primers, Proteins/chemistry, Purines/*chemistry, Recombinant, Replication, Retroelements/*genetics, Ribonuclease, RNA, RNA-Directed, RNA/chemistry, Sequence, Support, Templates, Thymus/chemistry, U.S., Viral

2002

Gottar Marie, Gobert Vanessa, Michel Tatiana, Belvin Marcia, Duyk Geoffrey, Hoffmann Jules A, Ferrandon Dominique, Royet Julien

The Drosophila immune response against Gram-negative bacteria is mediated by a peptidoglycan recognition protein Journal Article

In: Nature, vol. 416, pp. 640–644, 2002, ISBN: 0028-0836.

Abstract | Links | BibTeX | Tags: Animal, Anti-Infective Agents/metabolism, Carrier Proteins/biosynthesis/genetics/*immunology, Drosophila melanogaster/genetics/*immunology/*microbiology, Drosophila Proteins/genetics/metabolism, Epistasis, Female, ferrandon, Genes, Genetic, Genetic Predisposition to Disease, Gram-Negative Bacteria/*immunology/physiology, hoffmann, Human, Insect/genetics, M3i, Messenger/genetics/metabolism, Mutation, Non-U.S. Gov't, P.H.S., Phenotype, RNA, Signal Transduction, Support, Survival Rate, Transgenes/genetics, U.S. Gov't

Cristofari G., Bampi C., Wilhelm M., Wilhelm F. X., Darlix J. L.

A 5'-3' long-range interaction in Ty1 RNA controls its reverse transcription and retrotransposition Journal Article

In: EMBO J, vol. 21, no. 16, pp. 4368-79, 2002, (0261-4189 Journal Article).

Abstract | BibTeX | Tags: *Gene, *Transcription, Acid, cerevisiae/*genetics, Complementary/biosynthesis, Conformation, DNA, Expression, Fungal, Fungal/chemistry/*metabolism, Genetic, Gov't, in, Messenger/chemistry/*metabolism, Non-U.S., Nucleic, Phylogeny, Regulation, Retroelements/*genetics, RNA, Saccharomyces, Support, vitro

Mohr S., Leikauf G. D., Keith G., Rihn B. H.

Microarrays as cancer keys: an array of possibilities Journal Article

In: J Clin Oncol, vol. 20, no. 14, pp. 3165-75, 2002, (0732-183x Journal Article Review Review, Tutorial).

Abstract | BibTeX | Tags: (Genetics), *Gene, *Oligonucleotide, *Sequence, Aberrations, Analysis, Analysis/methods, Animals, Array, Chromosome, DNA/methods, Expression, Genotype, Gov't, Human, Mutation, Neoplasms/*genetics, Neoplastic, Oncogenes/*genetics, P.H.S., Polymorphism, Profiling/methods, Proteome/genetics, Regulation, Sequence, Support, U.S.

Perederina A., Nevskaya N., Nikonov O., Nikulin A., Dumas P., Yao M., Tanaka I., Garber M., Gongadze G., Nikonov S.

Detailed analysis of RNA-protein interactions within the bacterial ribosomal protein L5/5S rRNA complex Journal Article

In: RNA, vol. 8, no. 12, pp. 1548-57, 2002, (1355-8382 Journal Article).

Abstract | BibTeX | Tags: 5S/*chemistry/*metabolism, Acid, Amino, Bacterial, Base, Binding, Bonding, coli/genetics, Conformation, Data, Escherichia, Fragments/chemistry/metabolism, Gov't, Hydrogen, Models, Molecular, Non-U.S., Nucleic, Peptide, Protein, Proteins/*chemistry/*metabolism, Proteins/chemistry/metabolism, Ribosomal, RNA, Sequence, Sites, Support

Wilhelm M., Fishman J. A., Pontikis R., Aubertin A. M., Wilhelm F. X.

Susceptibility of recombinant porcine endogenous retrovirus reverse transcriptase to nucleoside and non-nucleoside inhibitors Journal Article

In: Cell Mol Life Sci, vol. 59, no. 12, pp. 2184-90, 2002, (1420-682x Journal Article).

Abstract | BibTeX | Tags: Acid, Amino, Animals, Calf, Chloride/metabolism, Chlorides/metabolism, Cloning, Compounds/metabolism, Data, DNA, DNA-Directed, endogenous, Gov't, H, Human, Inhibitors/*pharmacology, Magnesium, Manganese, Molecular, Non-U.S., Nucleosides/chemistry/*metabolism, P.H.S., Polymerase/chemistry/genetics/*metabolism, Polymerase/metabolism, Proteins/metabolism, Recombinant, Retroviruses/*enzymology, Reverse, Ribonuclease, RNA-Directed, Sequence, Sodium, structure, Support, Swine, Thymus/metabolism, Transcriptase, U.S.

2001

Boutabout M., Wilhelm M., Wilhelm F. X.

DNA synthesis fidelity by the reverse transcriptase of the yeast retrotransposon Ty1 Journal Article

In: Nucleic Acids Res, vol. 29, no. 11, pp. 2217-22, 2001, (1362-4962 Journal Article).

Abstract | BibTeX | Tags: cerevisiae/*genetics/metabolism, DNA, Fungal/genetics, Fungal/genetics/*metabolism, Genetic, Gov't, Kinetics, Non-U.S., Nucleotides/genetics/metabolism, Polymerase/*metabolism, Retroelements/*genetics, RNA, RNA-Directed, Saccharomyces, Support, Templates

Carnicelli D., Brigotti M., Rizzi S., Keith G., Montanaro L., Sperti S.

Nucleotides U28-A42 and A37 in unmodified yeast tRNA(Trp) as negative identity elements for bovine tryptophanyl-tRNA synthetase Journal Article

In: FEBS Lett, vol. 492, no. 3, pp. 238-41, 2001, (0014-5793 Journal Article).

Abstract | BibTeX | Tags: Acid, Adenine/chemistry, Animals, Base, Cattle, cerevisiae/genetics, Conformation, Data, Fungal/genetics/metabolism, Gov't, Kinetics, Ligase/*metabolism, Molecular, Non-U.S., Nucleic, RNA, Saccharomyces, Sequence, Species, Specificity, Substrate, Support, Transfer, Trp/chemistry/*metabolism, Tryptophan-tRNA, Uridine/chemistry

Wilhelm M., Uzun O., Mules E. H., Gabriel A., Wilhelm F. X.

Polypurine tract formation by Ty1 RNase H Journal Article

In: J Biol Chem, vol. 276, no. 50, pp. 47695-701, 2001, (0021-9258 Journal Article).

Abstract | BibTeX | Tags: *Purines, *Retroelements, Base, Binding, Calf, Data, DNA, DNA/metabolism, Factors, Gov't, H, Hydrolysis, Molecular, Mutation, Non-U.S., P.H.S., Polymerase/*chemistry/*metabolism, Primers/pharmacology, Protein, Proteins/metabolism, Recombinant, Ribonuclease, RNA-Directed, RNA/metabolism, Sequence, Sites, Support, Thymus/*chemistry/*genetics/metabolism, time, U.S.

2000

Delagoutte B., Keith G., Moras D., Cavarelli J.

Crystallization and preliminary X-ray crystallographic analysis of yeast arginyl-tRNA synthetase-yeast tRNAArg complexes Journal Article

In: Acta Crystallogr D Biol Crystallogr, vol. 56, no. Pt 4, pp. 492-4, 2000, (0907-4449 Journal Article).

Abstract | BibTeX | Tags: &, Arg/*chemistry/isolation, Arginine-tRNA, cerevisiae/enzymology/genetics, Crystallization, Crystallography, Fungal/chemistry/isolation, Gov't, Ligase/*chemistry/isolation, Non-U.S., purification/*metabolism, purification/metabolism, RNA, Saccharomyces, Support, Transfer, X-Ray

Postawski K., Olech-Fudali E., Jakowicki J. A., Korobowicz E., Keith G., Baranowski W.

[Overall genomic DNA methylation in relation to estrogen] Journal Article

In: Ginekol Pol, vol. 71, no. 9, pp. 1206-11, 2000, (0017-0011 Journal Article).

Abstract | BibTeX | Tags: 80, Abstract, Aged, and, Biopsy, DNA, English, Estrogen/*metabolism, Female, Gov't, Human, Methylases/metabolism, Methylation, Middle, modification, Neoplasms/*metabolism/*pathology, Non-U.S., over, Progesterone/*metabolism, Receptors, Support, Uterine, Uterus/*metabolism/pathology

Rihn B., Coulais C., Kauffer E., Bottin M. C., Martin P., Yvon F., Vigneron J. C., Binet S., Monhoven N., Steiblen G., Keith G.

Inhaled crocidolite mutagenicity in lung DNA Journal Article

In: Environ Health Perspect, vol. 108, no. 4, pp. 341-6, 2000, (0091-6765 Journal Article).

Abstract | BibTeX | Tags: &, Adducts/*genetics, Air, Alveolar/physiology, Animals, Asbestos, Crocidolite/administration, Damage/*genetics, DNA, dosage/*adverse, effects, effects/pathology, Exposure, Gov't, Inhalation, Lung/*drug, Macrophages, Male, Mice, Mutagenicity, Non-U.S., Pollutants/*adverse, Support, Tests, transgenic

Rihn B. H., Bottin M. C., Coulais C., Rouget R., Monhoven N., Baranowski W., Edorh A., Keith G.

Genotoxicity of 3-methylcholanthrene in liver of transgenic big Blue mice Journal Article

In: Environ Mol Mutagen, vol. 36, no. 4, pp. 266-73, 2000, (0893-6692 Journal Article).

Abstract | BibTeX | Tags: *Escherichia, Adducts, Animals, Bacterial, Base, C57BL, Cell, coli, Division/drug, DNA, effects, Gov't, Inbred, Liver/cytology/*drug, Methylcholanthrene/*toxicity, Mice, Mutagens/*toxicity, Mutation, Non-U.S., Organ, Primers, Proteins, Proteins/genetics, Repressor, Sequence, Support, transgenic, Weight

Wilhelm M., Boutabout M., Wilhelm F. X.

Expression of an active form of recombinant Ty1 reverse transcriptase in Escherichia coli: a fusion protein containing the C-terminal region of the Ty1 integrase linked to the reverse transcriptase-RNase H domain exhibits polymerase and RNase H activities Journal Article

In: Biochem J, vol. 348, no. Pt 2, pp. 337-42, 2000, (0264-6021 Journal Article).

Abstract | BibTeX | Tags: &, Acid, affinity, Alignment, Amino, Calf, cerevisiae/*enzymology/*genetics, Chromatography, Cloning, Codon, coli, Comparative, Data, DNA, DNA/metabolism, Escherichia, Frames, Fusion, Genetic, Gov't, H, Heteroduplexes/metabolism, HIV-1, Homology, Integrases/chemistry/metabolism, Kinetics, Molecular, Non-U.S., Nucleic, Open, Polymerase/chemistry/isolation, Proteins/chemistry/isolation, purification/*metabolism, purification/metabolism, Reading, Recombinant, Retroelements/*genetics, Reverse, Ribonuclease, RNA-Directed, RNA/metabolism, Saccharomyces, Sequence, Study, Support, Templates, Terminator, Thymus/isolation, Transcriptase/chemistry

Tzou P, Ohresser S, Ferrandon Dominique, Capovilla Maria, Reichhart Jean-Marc, Lemaitre Bruno, Hoffmann Jules A, Imler Jean-Luc

Tissue-specific inducible expression of antimicrobial peptide genes in Drosophila surface epithelia Journal Article

In: Immunity, vol. 13, pp. 737–48., 2000, ISSN: 1074-7613.

Abstract | BibTeX | Tags: *Genes, Animal, Anti-Infective Agents/*immunology/metabolism, Drosophila/genetics/*immunology, ferrandon, Gene Expression Regulation/*immunology, Genes, Glycoside Hydrolases/immunology, hoffmann, Human, imler, Insect, Insect Proteins/genetics/immunology, M3i, Non-U.S. Gov't, Organ Specificity, P.H.S., reichhart, Reporter, Support, Transfection, U.S. Gov't

1999

Auxilien S., Keith G., Grice S. F. Le, Darlix J. L.

Role of post-transcriptional modifications of primer tRNALys,3 in the fidelity and efficacy of plus strand DNA transfer during HIV-1 reverse transcription Journal Article

In: J Biol Chem, vol. 274, no. 7, pp. 4412-20, 1999, (0021-9258 Journal Article).

Abstract | BibTeX | Tags: *RNA, *Transcription, Acid, Base, Calf, Conformation, Data, DNA, Genetic, Gov't, H, HIV-1, HIV-1/*physiology, Lys/*metabolism, Molecular, Non-U.S., Nucleic, post-transcriptional, Processing, Reverse, Ribonuclease, RNA, Sequence, Support, Templates, Thymus/metabolism, Transcriptase/metabolism, Transfer, Viral/*metabolism, Viral/metabolism

Perreau V. M., Keith G., Holmes W. M., Przykorska A., Santos M. A., Tuite M. F.

The Candida albicans CUG-decoding ser-tRNA has an atypical anticodon stem-loop structure Journal Article

In: J Mol Biol, vol. 293, no. 5, pp. 1039-53, 1999, (0022-2836 Journal Article).

Abstract | BibTeX | Tags: *Nucleic, Acid, albicans/*genetics, Anticodon/*chemistry/*genetics/metabolism, Base, Candida, cerevisiae/genetics, Code/genetics, Conformation, Evolution, Fungal/chemistry/genetics/metabolism, Genetic, Gov't, Imidazoles/metabolism, Lead/metabolism, Methylation, Methyltransferases/metabolism, Molecular, Mutation/genetics, Non-P.H.S., Non-U.S., Nucleosides/genetics/metabolism, P.H.S., Ribonucleases/metabolism, RNA, Saccharomyces, Sequence, Ser/*chemistry/*genetics/metabolism, Solutions, Support, Transfer, tRNA, U.S.

Wilhelm M., Boutabout M., Heyman T., Wilhelm F. X.

Reverse transcription of the yeast Ty1 retrotransposon: the mode of first strand transfer is either intermolecular or intramolecular Journal Article

In: J Mol Biol, vol. 288, no. 4, pp. 505-10, 1999, (0022-2836 Journal Article).

Abstract | BibTeX | Tags: *Retroelements, *Transcription, Acid, Base, cerevisiae/*genetics, DNA, Genetic, Gov't, Non-U.S., Nucleic, Repetitive, Saccharomyces, Sequence, Sequences, Single-Stranded/genetics, Support

Wilhelm M., Heyman T., Boutabout M., Wilhelm F. X.

A sequence immediately upstream of the plus-strand primer is essential for plus-strand DNA synthesis of the Saccharomyces cerevisiae Ty1 retrotransposon Journal Article

In: Nucleic Acids Res, vol. 27, no. 23, pp. 4547-52, 1999, (0305-1048 Journal Article).

Abstract | BibTeX | Tags: *DNA, *Retroelements, Base, cerevisiae/*genetics, DNA, Elements, Fungal/*biosynthesis, Gov't, Mutation, Non-U.S., Primers, response, Saccharomyces, Sequence, Support

1998

Bergdoll M., Eltis L. D., Cameron A. D., Dumas P., Bolin J. T.

All in the family: structural and evolutionary relationships among three modular proteins with diverse functions and variable assembly Journal Article

In: Protein Sci, vol. 7, no. 8, pp. 1661-70, 1998, (0961-8368 Journal Article).

Abstract | BibTeX | Tags: *Acetyltransferases, *Evolution, Acid, Amino, Bacterial, Burkholderia/*chemistry, Crystallography, Data, Genetic, Gov't, Homology, Human, Lactoylglutathione, Lyase/*chemistry, Models, Molecular, Non-U.S., Oxygenases/chemistry, P.H.S., Phylogeny, Protein, Proteins/*chemistry, Secondary, Sequence, structure, Support, U.S., X-Ray

Brigotti M., Keith G., Pallanca A., Carnicelli D., Alvergna P., Dirheimer G., Montanaro L., Sperti S.

Identification of the tRNAs which up-regulate agrostin, barley RIP and PAP-S, three ribosome-inactivating proteins of plant origin Journal Article

In: FEBS Lett, vol. 431, no. 2, pp. 259-62, 1998, (0014-5793 Journal Article).

Abstract | BibTeX | Tags: &, Acid, Adenosine, Base, Conformation, Data, effects/*metabolism, Gov't, Hordeum/metabolism, Hydrolases/*metabolism, Molecular, N-Glycosyl, Non-U.S., Nucleic, Plant, Plant/chemistry/isolation, Proteins/drug, purification/*metabolism, RNA, Sequence, Support, Transfer/chemistry/isolation, Triphosphate/pharmacology, Up-Regulation

Duranton B., Keith G., Goss, Bergmann C., Schleiffer R., Raul F.

Concomitant changes in polyamine pools and DNA methylation during growth inhibition of human colonic cancer cells Journal Article

In: Exp Cell Res, vol. 243, no. 2, pp. 319-25, 1998, (0014-4827 Journal Article).

Abstract | BibTeX | Tags: *Cell, *DNA, &, Adenosylmethionine, Amidines/pharmacology, Caco-2, Cells, Decarboxylase/antagonists, Differentiation/drug, Division/drug, effects, Eflornithine/pharmacology, enzyme, Gov't, Human, Indans/pharmacology, inhibitors/metabolism, Inhibitors/pharmacology, Methylation, Non-U.S., Ornithine, Polyamines/*metabolism, Support

Friant S., Heyman T., Bystrom A. S., Wilhelm M., Wilhelm F. X.

Interactions between Ty1 retrotransposon RNA and the T and D regions of the tRNA(iMet) primer are required for initiation of reverse transcription in vivo Journal Article

In: Mol Cell Biol, vol. 18, no. 2, pp. 799-806, 1998, (0270-7306 Journal Article).

Abstract | BibTeX | Tags: *Retroelements, *Transcription, Acid, Base, Binding, cerevisiae, Conformation, Data, DNA, Fungal/*metabolism, Fungal/biosynthesis, Genetic, Gov't, Met/*metabolism, Molecular, Mutagenesis, Non-U.S., Nucleic, Primers, Replication, RNA, Saccharomyces, Sequence, Sites, Support, Transfer

Gabus C., Ficheux D., Rau M., Keith G., Sandmeyer S., Darlix J. L.

The yeast Ty3 retrotransposon contains a 5'-3' bipartite primer-binding site and encodes nucleocapsid protein NCp9 functionally homologous to HIV-1 NCp7 Journal Article

In: EMBO J, vol. 17, no. 16, pp. 4873-80, 1998, (0261-4189 Journal Article).

Abstract | BibTeX | Tags: *Capsid, *Retroelements, Acid, Base, Binding, Capsid/*genetics, cerevisiae/*genetics, dimerization, gag/*genetics, Gene, Gov't, Homology, Met/genetics/*metabolism, Non-U.S., Nucleic, P.H.S., Products, Proteins, RNA, Saccharomyces, Sequence, Sites, Support, Transfer, U.S.

Motorin Y., Keith G., Simon C., Foiret D., Simos G., Hurt E., Grosjean H.

The yeast tRNA:pseudouridine synthase Pus1p displays a multisite substrate specificity Journal Article

In: RNA, vol. 4, no. 7, pp. 856-69, 1998, (1355-8382 Journal Article).

Abstract | BibTeX | Tags: *RNA, cerevisiae, Cloning, Fractions/metabolism, Fungal, Fungal/metabolism, Gov't, Hydro-Lyases/biosynthesis/genetics/*metabolism, Molecular, Mutation, Non-U.S., Plant/metabolism, post-transcriptional, Precursors/*metabolism, Processing, Proteins/biosynthesis, Proteins/biosynthesis/genetics/metabolism, Pseudouridine/*biosynthesis, Recombinant, RNA, Saccharomyces, Specificity, Subcellular, Substrate, Support, Transfer/*metabolism

1997

Friant S., Heyman T., Poch O., Wilhelm M., Wilhelm F. X.

Sequence comparison of the Ty1 and Ty2 elements of the yeast genome supports the structural model of the tRNAiMet-Ty1 RNA reverse transcription initiation complex Journal Article

In: Yeast, vol. 13, no. 7, pp. 639-45, 1997, (0749-503x Journal Article).

Abstract | BibTeX | Tags: *Sequence, Acid, Alignment, Amino, Analysis, Base, Data, DNA, Elements/*genetics, Fungal/genetics, Gov't, Met/*chemistry/*genetics, Molecular, Non-U.S., RNA, Sequence, structure, Support, Transfer, Transposable, Yeasts/*genetics

Wilhelm M., Heyman T., Friant S., Wilhelm F. X.

Heterogeneous terminal structure of Ty1 and Ty3 reverse transcripts Journal Article

In: Nucleic Acids Res, vol. 25, no. 11, pp. 2161-6, 1997, (0305-1048 Journal Article).

Abstract | BibTeX | Tags: *Nucleic, *Transcription, Acid, Calf, Chain, Conformation, DNA, Fungal/*chemistry/metabolism, Genetic, Gov't, H, Hybridization, Non-U.S., Nucleic, Plasmids/chemistry/genetics/metabolism, Polymerase, Reaction, Replication, Retroelements/*genetics, Ribonuclease, RNA, Support, Thymus/metabolism, Transfer/chemistry

1996

Friant S., Heyman T., Wilhelm F. X., Wilhelm M.

Role of RNA primers in initiation of minus-strand and plus-strand DNA synthesis of the yeast retrotransposon Ty1 Journal Article

In: Biochimie, vol. 78, no. 7, pp. 674-80, 1996, (0300-9084 Journal Article).

Abstract | BibTeX | Tags: *DNA, Acid, Bacterial/*metabolism, Complementary/metabolism, Conformation, Data, DNA, Elements, Gov't, Molecular, Mutagenesis, Non-U.S., Nucleic, Replication, RNA, RNA/*metabolism, Sequence, Support, Transposable

Friant S., Heyman T., Wilhelm M. L., Wilhelm F. X.

Extended interactions between the primer tRNAi(Met) and genomic RNA of the yeast Ty1 retrotransposon Journal Article

In: Nucleic Acids Res, vol. 24, no. 3, pp. 441-9, 1996, (0305-1048 Journal Article).

Abstract | BibTeX | Tags: Acid, Base, cerevisiae, Conformation, Data, Gov't, Met/genetics/*metabolism, Molecular, Mutation, Non-U.S., Nucleic, Retroelements/*genetics, RNA, RNA/genetics/*metabolism, Saccharomyces, Sequence, structure, Support, Transfer

de Barros J. P. Pais, Keith G., Adlouni C. El, Glasser A. L., Mack G., Dirheimer G., Desgres J.

2'-O-methyl-5-formylcytidine (f5Cm), a new modified nucleotide at the 'wobble' of two cytoplasmic tRNAs Leu (NAA) from bovine liver Journal Article

In: Nucleic Acids Res, vol. 24, no. 8, pp. 1489-96, 1996, (0305-1048 Journal Article).

Abstract | BibTeX | Tags: &, Acid, Acyl/*chemistry/isolation, Amino, Animals, Base, Borohydrides/chemistry, Cattle, Cells, Conformation, Cytidine/*analogs, Cytoplasm, Data, derivatives/chemistry/isolation, Fragmentography, Gov't, Hela, Human, Liver/*chemistry, Mass, Molecular, Non-U.S., Nucleic, purification, RNA, Sequence, structure, Support, Transfer

1995

Dirheimer G., Baranowski W., Keith G.

Variations in tRNA modifications, particularly of their queuine content in higher eukaryotes. Its relation to malignancy grading Journal Article

In: Biochimie, vol. 77, no. 1-2, pp. 99-103, 1995, (0300-9084 Journal Article Review Review, Tutorial).

Abstract | BibTeX | Tags: &, Animals, Cell, derivatives/analysis, Female, Gov't, Guanine/*analogs, Human, Neoplasms/*genetics/pathology, Neoplastic/genetics, Non-U.S., Ovarian, post-transcriptional, Processing, Purines/analysis, Pyrimidines/analysis, RNA, Support, Transfer/*chemistry/metabolism, Transformation

Gabryszuk J., Keith G., Monko M., Kuligowska E., Dirheimer G., Szarkowski J. W., Przykorska A.

Structural specificity of nuclease from wheat chloroplasts stroma Journal Article

In: Nucleic Acids Symp Ser, no. 33, pp. 115-9, 1995, (0261-3166 Journal Article).

Abstract | BibTeX | Tags: &, Acid, Asp/chemistry/genetics/metabolism, Base, Binding, Chloroplasts/*enzymology, Conformation, Data, Endonucleases/isolation, Fungal/chemistry/genetics/metabolism, Gov't, Molecular, Non-U.S., Nucleic, Phe/chemistry/genetics/metabolism, purification/*metabolism, RNA, RNA/chemistry/metabolism, Sequence, Sites, Specificity, Substrate, Support, Transfer, Triticum/*enzymology

Heyman T., Agoutin B., Friant S., Wilhelm F. X., Wilhelm M. L.

Plus-strand DNA synthesis of the yeast retrotransposon Ty1 is initiated at two sites, PPT1 next to the 3' LTR and PPT2 within the pol gene. PPT1 is sufficient for Ty1 transposition Journal Article

In: J Mol Biol, vol. 253, no. 2, pp. 291-303, 1995, (0022-2836 Journal Article).

Abstract | BibTeX | Tags: *DNA, *Genes, *Repetitive, *Retroelements, Acid, Base, C/analysis, cerevisiae/genetics/*virology, Chain, Cloning, Data, DNA, Fungal, Fungal/biosynthesis, Genes, Genetic, Genome, Gov't, Mapping, Molecular, Non-U.S., Nucleic, pol, Poly, Polymerase, Primers, Reaction, Replication, Restriction, Saccharomyces, Sequence, Sequences, Support, Transcription, Viral, Viral/*biosynthesis

Keith G., Dirheimer G.

Postlabeling: a sensitive method for studying DNA adducts and their role in carcinogenesis Journal Article

In: Curr Opin Biotechnol, vol. 6, no. 1, pp. 3-11, 1995, (0958-1669 Journal Article Review Review, Academic).

Abstract | BibTeX | Tags: *Cell, *Genome, Adducts/*analysis, and, Animals, Base, Cell, Conditions/genetics/pathology, Data, Dilution, Division, DNA, Genetic, Gov't, Human, Models, Molecular, Mutagenesis, Neoplasms/*genetics/pathology, Neoplastic, Non-U.S., Phosphorus, Precancerous, Radioisotope, Radioisotopes, Sensitivity, Sequence, Specificity, Support, Technique, Transformation, Xenobiotics

O'Connor M., Brunelli C. A., Firpo M. A., Gregory S. T., Lieberman K. R., Lodmell J. S., Moine H., Ryk D. I. Van, Dahlberg A. E.

Genetic probes of ribosomal RNA function Journal Article

In: Biochem Cell Biol, vol. 73, no. 11-12, pp. 859-68, 1995, (0829-8211 Journal Article Review Review, Tutorial).

Abstract | BibTeX | Tags: 16S/genetics, Acid, Base, Conformation, Data, Gov't, Messenger/genetics, Molecular, Mutation, Non-U.S., Nucleic, P.H.S., Probes, Ribosomal, Ribosomal/*genetics, RNA, Sequence, Support, Transfer/genetics, U.S.

1994

Baranowski W., Dirheimer G., Jakowicki J. A., Keith G.

Deficiency of queuine, a highly modified purine base, in transfer RNAs from primary and metastatic ovarian malignant tumors in women Journal Article

In: Cancer Res, vol. 54, no. 16, pp. 4468-71, 1994, (0008-5472 Journal Article).

Abstract | BibTeX | Tags: &, Adolescent, Adult, Aged, derivatives/analysis, Female, Gov't, Guanine/*analogs, Human, Middle, Neoplasm/*chemistry, Neoplasms/*chemistry/pathology, Non-U.S., Ovarian, RNA, Support, Transfer/*chemistry

Dumas P., Bergdoll M., Cagnon C., Masson J. M.

Crystal structure and site-directed mutagenesis of a bleomycin resistance protein and their significance for drug sequestering Journal Article

In: EMBO J, vol. 13, no. 11, pp. 2483-92, 1994, (0261-4189 Journal Article).

Abstract | BibTeX | Tags: *Acetyltransferases, &, Acid, Amino, Bacterial, Bacterial/*genetics, Base, Binding, Bleomycin/*metabolism/pharmacology, Conformation, Crystallization, Crystallography, Data, Drug, Fusion, Genes, Gov't, Microbial/genetics, Models, Molecular, Mutagenesis, Non-U.S., Protein, Proteins/*chemistry/genetics/isolation, Proteins/isolation, purification, purification/metabolism, Recombinant, Relationship, Resistance, Secondary, Sequence, Site-Directed, Sites, Structural, structure, Structure-Activity, Support, X-Ray

Moine H., Dahlberg A. E.

Mutations in helix 34 of Escherichia coli 16 S ribosomal RNA have multiple effects on ribosome function and synthesis Journal Article

In: J Mol Biol, vol. 243, no. 3, pp. 402-12, 1994, (0022-2836 Journal Article).

Abstract | BibTeX | Tags: *Mutation, *Nucleic, *Translation, &, 16S/*chemistry/genetics, Acid, Base, beta-Galactosidase/genetics, Codon, coli/*genetics/growth, Conformation, Data, development, Escherichia, Genetic, Gov't, Molecular, Non-U.S., P.H.S., Ribosomal, Ribosomes/*metabolism, RNA, Sequence, Support, Terminator, U.S.

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