Direct access Research units

Study and modeling of nutrients (selenium, vitamin E) effect using the sensitized transgenic Sepn1-/- mouse model

SelenoN-/- mouse is used as an integrative model to study redox homeostasis regulation in response to stress. The impaired defense toward oxidative stress in the SelenoN-/- mouse allows specific studies on the control mechanisms in response to different stresses. This animal model will be used to determine the protective role of nutritional supplies (seleno-organic compounds, vitamin E) on the stress susceptibility.

Picture of mouse