Pathogenesis of bacterial infections and immunity

@article{van_den_bossche_efficient_2010,

title = {Efficient receptor-independent intracellular translocation of aptamers mediated by conjugation to carbon nanotubes},

author = {Jeroen Van den Bossche and Wafa' T Al-Jamal and Bowen Tian and Antonio Nunes and Chiara Fabbro and Alberto Bianco and Maurizio Prato and Kostas Kostarelos},

doi = {10.1039/c0cc02092c},

issn = {1364-548X},

year  = {2010},

date = {2010-10-01},

journal = {Chemical Communications (Cambridge, England)},

volume = {46},

number = {39},

pages = {7379--7381},

abstract = {We have covalently grafted aptamers onto carboxylated carbon nanotubes to design a novel vector system that can easily translocate into the cytosol of different cell types independent of receptor-mediated uptake. We propose the use of carbon nanotubes for the efficient intracellular delivery of biologically active aptamers for potential therapeutic applications.},

keywords = {Aptamers, Base Sequence, Biological Transport, carbon, Cell Line, Cell Surface, DNA Primers, Electron, Electrophoresis, Humans, I2CT, Microscopy, Nanotubes, Nucleotide, Polyacrylamide Gel, Receptors, Team-Bianco, Transmission, tumor},

pubstate = {published},

tppubtype = {article}

}