Pathogenesis of bacterial infections and immunity

@article{parietti_rituximab_2010,

title = {Rituximab treatment overcomes reduction of regulatory iNKT cells in patients with rheumatoid arthritis},

author = {Véronique Parietti and Hélène Chifflot and Jean Sibilia and Sylviane Muller and Fanny Monneaux},

doi = {10.1016/j.clim.2009.11.007},

issn = {1521-7035},

year  = {2010},

date = {2010-01-01},

journal = {Clinical Immunology (Orlando, Fla.)},

volume = {134},

number = {3},

pages = {331--339},

abstract = {Invariant natural killer T (iNKT) cells are a subset of T cells that recognize glycolipid antigens presented by the CD1d molecule. Accumulating evidences showed that iNKT cells are implicated in the regulatory mechanisms that control autoimmunity. We evaluated the number of circulating iNKT cells in patients with rheumatoid arthritis (RA) by flow cytometry and performed a longitudinal analysis of iNKT cell frequency in RA patients who were given an anti-CD20 therapy. Significantly lower iNKT cell numbers were measured in the blood from RA patients compared to healthy individuals (ptextless0.0001) and low iNKT cell frequencies were rather associated with an active disease. In RA patients who received rituximab treatment, iNKT cell number was increased in relation to the clinical outcome. We demonstrated that the number of iNKT cells is altered in RA patients and that following rituximab therapy, clinical remission of RA is associated with an increase of iNKT cell frequency.},

keywords = {Adult, Age Factors, Aged, Antibodies, Antirheumatic Agents, arthritis, Female, Flow Cytometry, Humans, I2CT, Longitudinal Studies, Male, Middle Aged, Monneaux, Monoclonal, Murine-Derived, Natural Killer T-Cells, Nonparametric, rheumatoid, Rituximab, Sex Factors, Statistics, Team-Dumortier, Young Adult},

pubstate = {published},

tppubtype = {article}

}

@article{bang_identification_1976,

title = {Identification, by gas chromatography and mass spectrometry, of ecdysone synthesized in the ovaries of adult female Locusta migratoria (Insecta, Orthoptera)},

author = {L Bang and Marie Lagueux and M Hirn and Jules A Hoffmann},

year  = {1976},

date = {1976-10-01},

journal = {C.R. Hebd. Seances Acad. Sci., Ser. D, Sci. Nat.},

volume = {283},

number = {9},

pages = {1081--1084},

abstract = {Gas chromatographic analysis, coupled to mass spectrometry, demonstrates that the considerable amounts of ecdysteroids produced in the ovaries of female adults of Locusta migratoria at the end of each ovarian cycle, consist predominantly of ecdysone.},

keywords = {Age Factors, Animals, Chromatography, Ecdysone, Female, Gas, Grasshoppers, hoffmann, M3i, Mass Spectrometry, Ovary},

pubstate = {published},

tppubtype = {article}

}

@article{feyereisen_hemolymphatic_1975,

title = {The hemolymphatic transport of molting hormone during the development of Locusta migratoria L},

author = {R Feyereisen and Marie Lagueux and Jules A Hoffmann},

year  = {1975},

date = {1975-04-01},

journal = {C.R. Hebd. Seances Acad. Sci., Ser. D, Sci. Nat.},

volume = {280},

number = {14},

pages = {1709--1712},

abstract = {Shortly after injection of radio-labelled ecdysone into fifth instar larvae of Locusta migratoria, 20-hydroxy-ecdysone (ecdysterone) is the main hormone found in the blood. Some 10% of the circulating hormone are bound to hemolymph macromolecules. The ratio of bound to free hormone is stage-dependent; it decreases considerably after previous injections of non-labelled ecdysone, but increases in insects in which ecdysone biosynthesis has been blocked by extirpation of the prothoracic glands or selective X-ray treatment of the hemocytopoietic tissue.},

keywords = {Age Factors, Animals, Carrier Proteins, Chromatography, Ecdysone, Ecdysterone, Gel, Grasshoppers, Hematopoietic System, hoffmann, Larva, M3i, Neurosecretory Systems, Protein Binding, Time Factors},

pubstate = {published},

tppubtype = {article}

}

@article{hoffmann_molting_1974,

title = {Molting hormone titer and metabolic fate of injected ecdysone during the fifth larval instar and in adults of Locusta migratoria (Orthoptera)},

author = {Jules A Hoffmann and J Koolman and P Karlson and P Joly},

issn = {0016-6480},

year  = {1974},

date = {1974-01-01},

journal = {Gen. Comp. Endocrinol.},

volume = {22},

number = {1},

pages = {90--97},

keywords = {Age Factors, Animals, Chromatography, Ecdysone, Feces, Grasshoppers, hoffmann, Hydroxylation, Invertebrate Hormones, Larva, M3i, Thin Layer, Time Factors, Tritium},

pubstate = {published},

tppubtype = {article}

}

@article{joly_development_1973,

title = {Development of the prothoracic glands of permanent larvae of Locusta migratoria obtained by selective irradiation of the hemocytopoietic tissue},

author = {L Joly and M J Weins and Jules A Hoffmann and A Porte},

issn = {0340-0336},

year  = {1973},

date = {1973-02-01},

journal = {Z Zellforsch Mikrosk Anat},

volume = {137},

number = {3},

pages = {387--397},

keywords = {Age Factors, Animals, Biological, Ecdysone, Electron, Endocrine Glands, Golgi Apparatus, Grasshoppers, hoffmann, Larva, M3i, Metamorphosis, Microscopy, Radiation Effects, ribosomes},

pubstate = {published},

tppubtype = {article}

}