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2021

Arquier Nathalie, Bjordal Marianne, Hammann Philippe, Kuhn Lauriane, Léopold Pierre

Brain adiponectin signaling controls peripheral insulin response in Drosophila Journal Article

In: Nature Communications, vol. 12, no. 1, pp. 5633, 2021, ISSN: 2041-1723.

Abstract | Links | BibTeX | Tags: Adiponectin, Animals, Brain, Cell Line, Drosophila melanogaster, Drosophila Proteins, Energy Metabolism, Genetically Modified, Hemolymph, Homeostasis, Insulin, Juvenile Hormones, Larva, Neurons, PPSE, Receptors, Signal Transduction

2009

Shia Alice K H, Glittenberg Marcus, Thompson Gavin, Weber Alexander N R, Reichhart Jean-Marc, Ligoxygakis Petros

Toll-dependent antimicrobial responses in Drosophila larval fat body require Spätzle secreted by haemocytes Journal Article

In: J. Cell. Sci., vol. 122, no. Pt 24, pp. 4505–4515, 2009, ISSN: 1477-9137.

Abstract | Links | BibTeX | Tags: Animals, Enterococcus faecalis, Escherichia coli, Fat Body, Hemocytes, Larva, M3i, reichhart, Toll-Like Receptors

2006

Bischoff Vincent, Vignal Cécile, Duvic Bernard, Boneca Ivo G, Hoffmann Jules A, Royet Julien

Downregulation of the Drosophila immune response by peptidoglycan-recognition proteins SC1 and SC2 Journal Article

In: PLoS Pathog., vol. 2, no. 2, pp. e14, 2006, ISSN: 1553-7374.

Abstract | Links | BibTeX | Tags: Animals, Antimicrobial Cationic Peptides, bacteria, Carrier Proteins, Down-Regulation, hoffmann, Larva, M3i, RNA Interference, Signal Transduction

2005

Irving Phil, Ubeda Jean-Michel, Doucet Daniel, Troxler Laurent, Lagueux Marie, Zachary Daniel, Hoffmann Jules A, Hetru Charles, Meister Marie

New insights into Drosophila larval haemocyte functions through genome-wide analysis Journal Article

In: Cell. Microbiol., vol. 7, no. 3, pp. 335–350, 2005, ISSN: 1462-5814.

Abstract | Links | BibTeX | Tags: Animals, bioinformatic, Catechol Oxidase, Cell Lineage, Enzyme Precursors, Escherichia coli, Fat Body, Gene Expression Profiling, Genome, Hemocytes, hoffmann, Integrin alpha Chains, Integrins, Larva, M3i, Micrococcus luteus

Fauny Jean Daniel, Silber Joël, Zider Alain

Drosophila Lipid Storage Droplet 2 gene (Lsd-2) is expressed and controls lipid storage in wing imaginal discs Journal Article

In: Developmental Dynamics: An Official Publication of the American Association of Anatomists, vol. 232, no. 3, pp. 725–732, 2005, ISSN: 1058-8388.

Abstract | Links | BibTeX | Tags: Animals, Biological, Drosophila, Drosophila Proteins, Embryo, Fat Body, Genes, I2CT, Imagerie, Insect, Larva, Lipid Metabolism, Metamorphosis, Mutation, Nonmammalian, Nuclear Proteins, Phosphoproteins, Wing

2002

Munier Anne-Isabelle, Doucet Daniel, Perrodou Emmanuel, Zachary Daniel, Meister Marie, Hoffmann Jules A, Janeway Charles A, Lagueux Marie

PVF2, a PDGF/VEGF-like growth factor, induces hemocyte proliferation in Drosophila larvae Journal Article

In: EMBO Rep., vol. 3, no. 12, pp. 1195–1200, 2002, ISSN: 1469-221X.

Abstract | Links | BibTeX | Tags: Animals, Antibodies, Blotting, Cell Differentiation, Hemocytes, hoffmann, Immunohistochemistry, Larva, ligands, M3i, Platelet-Derived Growth Factor, Receptors, Vascular Endothelial Growth Factor, Western

Kambris Zakaria, Hoffmann Jules A, Imler Jean-Luc, Capovilla Maria

Tissue and stage-specific expression of the Tolls in Drosophila embryos Journal Article

In: Gene expression patterns: GEP, vol. 2, no. 3-4, pp. 311–317, 2002, ISSN: 1567-133X.

Abstract | BibTeX | Tags: Animals, Blotting, Cell Surface, Gene Expression Profiling, hoffmann, imler, Larva, M3i, Multigene Family, Northern, Receptors, Toll-Like Receptors

Duvic Bernard, Hoffmann Jules A, Meister Marie, Royet Julien

Notch signaling controls lineage specification during Drosophila larval hematopoiesis Journal Article

In: Curr. Biol., vol. 12, no. 22, pp. 1923–1927, 2002, ISSN: 0960-9822.

Abstract | BibTeX | Tags: Animals, Cell Differentiation, Hematopoiesis, hoffmann, Larva, Lymphoid Tissue, M3i, Membrane Proteins, Notch, Receptors, Signal Transduction

Ligoxygakis Petros, Bulet Philippe, Reichhart Jean-Marc

Critical evaluation of the role of the Toll-like receptor 18-Wheeler in the host defense of Drosophila Journal Article

In: EMBO Rep., vol. 3, no. 7, pp. 666–673, 2002, ISSN: 1469-221X.

Abstract | Links | BibTeX | Tags: Animals, Anti-Bacterial Agents, Antimicrobial Cationic Peptides, Cell Adhesion Molecules, Fat Body, Gene Expression Regulation, Genes, Immunohistochemistry, Immunologic, Insect, Insect Proteins, Larva, M3i, Mass, Matrix-Assisted Laser Desorption-Ionization, Membrane Proteins, Receptors, reichhart, Reporter, Spectrometry, Transgenes

2000

Basset A, Khush R S, Braun A, Gardan L, Boccard F, Hoffmann Jules A, Lemaitre Bruno

The phytopathogenic bacteria Erwinia carotovora infects Drosophila and activates an immune response Journal Article

In: Proc. Natl. Acad. Sci. U.S.A., vol. 97, no. 7, pp. 3376–3381, 2000, ISSN: 0027-8424.

Abstract | Links | BibTeX | Tags: Animals, Bacterial, Gene Expression Regulation, Genetically Modified, hoffmann, Insect Proteins, Larva, M3i, Pectobacterium carotovorum

Imler Jean-Luc, Hoffmann Jules A

Toll and Toll-like proteins: an ancient family of receptors signaling infection Journal Article

In: Reviews in Immunogenetics, vol. 2, no. 3, pp. 294–304, 2000, ISSN: 1398-1714.

Abstract | BibTeX | Tags: Adaptor Proteins, Animals, Antigens, Autoantigens, CD14, Cell Adhesion Molecules, Cell Surface, Differentiation, DNA-Binding Proteins, Gene Expression Regulation, hoffmann, I-kappa B Proteins, imler, Immunity, Immunologic, infection, Innate, Insect Proteins, Interleukin-1 Receptor-Associated Kinases, Knockout, Larva, Lipopolysaccharides, M3i, Mammals, MAP Kinase Signaling System, Membrane Glycoproteins, Membrane Proteins, Mice, Multigene Family, Myeloid Differentiation Factor 88, NF-kappa B, peptidoglycan, Phosphorylation, Post-Translational, Protein Kinases, Protein Processing, Protein Structure, Receptors, Recombinant Fusion Proteins, Signal Transducing, Signal Transduction, Teichoic Acids, Tertiary, Toll-Like Receptor 4, Toll-Like Receptor 5, Toll-Like Receptor 6, Toll-Like Receptor 9, Toll-Like Receptors, Ubiquitins

1999

Manfruelli P, Reichhart Jean-Marc, Steward R, Hoffmann Jules A, Lemaitre Bruno

A mosaic analysis in Drosophila fat body cells of the control of antimicrobial peptide genes by the Rel proteins Dorsal and DIF Journal Article

In: EMBO J., vol. 18, no. 12, pp. 3380–3391, 1999, ISSN: 0261-4189.

Abstract | Links | BibTeX | Tags: Animals, Anti-Infective Agents, Cell Surface, Clone Cells, DNA-Binding Proteins, Fat Body, Female, Gene Expression Regulation, Genes, hoffmann, Insect, Insect Proteins, Larva, M3i, Male, Membrane Glycoproteins, Mosaicism, Mutation, Nuclear Proteins, Phosphoproteins, Receptors, reichhart, Reporter, Signal Transduction, Toll-Like Receptors, Transcription Factors

Lamberty M, Ades S, Uttenweiler-Joseph S, Brookhart G, Bushey D, Hoffmann Jules A, Bulet Philippe

Insect immunity. Isolation from the lepidopteran Heliothis virescens of a novel insect defensin with potent antifungal activity Journal Article

In: J. Biol. Chem., vol. 274, no. 14, pp. 9320–9326, 1999, ISSN: 0021-9258.

Abstract | BibTeX | Tags: Amino Acid, Animals, Antifungal Agents, Capillary, Chromatography, Defensins, Electrophoresis, Escherichia coli, Hemolymph, High Pressure Liquid, hoffmann, Insect Proteins, Larva, Lepidoptera, M3i, Micrococcus luteus, Proteins, Sequence Homology

1998

Braun A, Hoffmann Jules A, Meister Marie

Analysis of the Drosophila host defense in domino mutant larvae, which are devoid of hemocytes Journal Article

In: Proc. Natl. Acad. Sci. U.S.A., vol. 95, no. 24, pp. 14337–14342, 1998, ISSN: 0027-8424.

Abstract | BibTeX | Tags: Adipose Tissue, Animals, Candida, Escherichia coli, Fungal, Genotype, Hemocytes, hoffmann, Larva, M3i, Melanins, Micrococcus luteus, Spores

Ferrandon Dominique, Jung Alain C, Criqui M, Lemaitre Bruno, Uttenweiler-Joseph S, Michaut Lydia, Reichhart Jean-Marc, Hoffmann Jules A

A drosomycin-GFP reporter transgene reveals a local immune response in Drosophila that is not dependent on the Toll pathway Journal Article

In: EMBO J., vol. 17, no. 5, pp. 1217–1227, 1998, ISSN: 0261-4189.

Abstract | Links | BibTeX | Tags: Animals, bacteria, Cell Surface, Developmental, Digestive System, Epithelium, Fat Body, Female, ferrandon, Fungal, Gene Expression Regulation, Genes, Green Fluorescent Proteins, hoffmann, Insect Proteins, Larva, Luminescent Proteins, M3i, Male, Membrane Glycoproteins, Organ Specificity, Receptors, reichhart, Reporter, Respiratory System, Spores, Toll-Like Receptors, Trachea, Transgenes

Nicolas E, Reichhart Jean-Marc, Hoffmann Jules A, Lemaitre Bruno

In vivo regulation of the IkappaB homologue cactus during the immune response of Drosophila Journal Article

In: J. Biol. Chem., vol. 273, no. 17, pp. 10463–10469, 1998, ISSN: 0021-9258.

Abstract | BibTeX | Tags: Animals, Cell Surface, DNA-Binding Proteins, Gene Expression Regulation, hoffmann, Insect Proteins, Larva, M3i, Membrane Glycoproteins, Phosphoproteins, Proto-Oncogene Proteins, Receptors, reichhart, Signal Transduction, Toll-Like Receptors, Transcription Factor RelB, Transcription Factors

Levashina Elena A, Ohresser S, Lemaitre Bruno, Imler Jean-Luc

Two distinct pathways can control expression of the gene encoding the Drosophila antimicrobial peptide metchnikowin Journal Article

In: Journal of Molecular Biology, vol. 278, no. 3, pp. 515–527, 1998, ISSN: 0022-2836.

Abstract | Links | BibTeX | Tags: Animals, Anti-Infective Agents, Antimicrobial Cationic Peptides, Base Sequence, Cloning, Gene Expression Regulation, Genes, Genetic, Genetically Modified, Glycopeptides, imler, Insect, Insect Proteins, Larva, M3i, Molecular, Mutation, Peptides, Promoter Regions, Recombinant Fusion Proteins, Reporter, Restriction Mapping, Transcription

1996

Richman A M, Bulet Philippe, Hetru Charles, Barillas-Mury Carolina, Hoffmann Jules A, Kafalos Fotis C

Inducible immune factors of the vector mosquito Anopheles gambiae: biochemical purification of a defensin antibacterial peptide and molecular cloning of preprodefensin cDNA Journal Article

In: Insect Mol. Biol., vol. 5, no. 3, pp. 203–210, 1996, ISSN: 0962-1075.

Abstract | BibTeX | Tags: Amino Acid, Animals, Anopheles, Base Sequence, Blood Bactericidal Activity, Blood Proteins, Cloning, Complementary, Defensins, DNA, Escherichia coli, Female, Gene Expression, Genes, hoffmann, Insect, Insect Vectors, Larva, M3i, Micrococcus luteus, Molecular, Sequence Homology

1995

Bulet Philippe, Hegy G, Lambert J, van Dorsselaer Alan, Hoffmann Jules A, Hetru Charles

Insect immunity. The inducible antibacterial peptide diptericin carries two O-glycans necessary for biological activity Journal Article

In: Biochemistry, vol. 34, no. 22, pp. 7394–7400, 1995, ISSN: 0006-2960.

Abstract | BibTeX | Tags: Animals, Anti-Bacterial Agents, Carbohydrate Sequence, Carbohydrates, Diptera, Escherichia coli, Glycopeptides, Hemolymph, hoffmann, Insect Hormones, Insect Proteins, Larva, M3i, Mass Spectrometry, Plants, Trisaccharides

1994

Dimarcq Jean-Luc, Hoffmann Danièle, Meister Marie, Bulet Philippe, Lanot R, Reichhart Jean-Marc, Hoffmann Jules A

Characterization and transcriptional profiles of a Drosophila gene encoding an insect defensin. A study in insect immunity Journal Article

In: Eur. J. Biochem., vol. 221, no. 1, pp. 201–209, 1994, ISSN: 0014-2956.

Abstract | BibTeX | Tags: Animals, Base Sequence, Blood Proteins, Chromosome Mapping, Cloning, Complementary, Defensins, DNA, Gene Expression, Genetic, Gram-Positive Bacteria, hoffmann, Larva, M3i, Molecular, Molecular Structure, Nucleic Acid, Protein Precursors, Regulatory Sequences, reichhart, Transcription

1993

Georgel Philippe, Meister Marie, Kappler Christine, Lemaitre Bruno, Reichhart Jean-Marc, Hoffmann Jules A

Insect immunity: the diptericin promoter contains multiple functional regulatory sequences homologous to mammalian acute-phase response elements Journal Article

In: Biochem. Biophys. Res. Commun., vol. 197, no. 2, pp. 508–517, 1993, ISSN: 0006-291X.

Abstract | Links | BibTeX | Tags: Acute-Phase Proteins, Animals, Anti-Infective Agents, Base Sequence, Cell Line, Deoxyribonuclease I, DNA-Binding Proteins, Genetic, hoffmann, Insect Hormones, Insect Proteins, Larva, M3i, Mammals, NF-kappa B, Nucleic Acid, Oligonucleotide Probes, Polymerase Chain Reaction, Promoter Regions, Regulatory Sequences, reichhart

1992

Bulet Philippe, Cociancich S, Reuland M, Sauber F, Bischoff R, Hegy G, Dorsselaer Van A, Hetru Charles, Hoffmann Jules A

A novel insect defensin mediates the inducible antibacterial activity in larvae of the dragonfly Aeschna cyanea (Paleoptera, Odonata) Journal Article

In: Eur. J. Biochem., vol. 209, no. 3, pp. 977–984, 1992, ISSN: 0014-2956.

Abstract | BibTeX | Tags: Animals, Anti-Bacterial Agents, Antimicrobial Cationic Peptides, Blood Bactericidal Activity, Blood Proteins, Defensins, Hemolymph, hoffmann, Insect Proteins, insects, Larva, M3i, Mass Spectrometry, Peptides

1990

Dimarcq Jean-Luc, Zachary Daniel, Hoffmann Jules A, Hoffmann Danièle, Reichhart Jean-Marc

Insect immunity: expression of the two major inducible antibacterial peptides, defensin and diptericin, in Phormia terranovae Journal Article

In: EMBO J., vol. 9, no. 8, pp. 2507–2515, 1990, ISSN: 0261-4189.

Abstract | BibTeX | Tags: Animals, Anti-Bacterial Agents, Base Sequence, Blood Proteins, Cloning, Defensins, Diptera, Gene Expression, hoffmann, Insect Hormones, Insect Proteins, Larva, M3i, Molecular, Nucleic Acid Hybridization, Oligonucleotide Probes, Protein Conformation, reichhart

1988

Dimarcq Jean-Luc, Keppi E, Dunbar B, Lambert J, Reichhart Jean-Marc, Hoffmann Danièle, Rankine S M, Fothergill J E, Hoffmann Jules A

Insect immunity. Purification and characterization of a family of novel inducible antibacterial proteins from immunized larvae of the dipteran Phormia terranovae and complete amino-acid sequence of the predominant member, diptericin A Journal Article

In: Eur. J. Biochem., vol. 171, no. 1-2, pp. 17–22, 1988, ISSN: 0014-2956.

Abstract | BibTeX | Tags: Amino Acids, Animals, Anti-Bacterial Agents, Diptera, Escherichia coli, hoffmann, Insect Hormones, Insect Proteins, Isoelectric Point, Larva, M3i, reichhart

1985

Meister Marie F, Dimarcq Jean-Luc, Kappler Christine, Hetru Charles, Lagueux Marie, Lanot R, Luu B, Hoffmann Jules A

Conversion of a radiolabelled ecdysone precursor, 2,22,25-trideoxyecdysone, by embryonic and larval tissues of Locusta migratoria Journal Article

In: Mol. Cell. Endocrinol., vol. 41, no. 1, pp. 27–44, 1985, ISSN: 0303-7207.

Abstract | BibTeX | Tags: Abdomen, Animals, Cholestenones, Chromatography, Ecdysone, Epidermis, Fat Body, Grasshoppers, Head, High Pressure Liquid, hoffmann, Hydroxylation, Larva, M3i, Malpighian Tubules, Thorax

1980

Zachary Daniel, Hoffmann Jules A

Endocrine control of the metamorphosis of the larval muscles in Calliphora erythrocephala (Diptera): in vitro studies of the role of ecdysteroids Journal Article

In: Dev. Biol., vol. 80, no. 1, pp. 235–247, 1980, ISSN: 0012-1606.

BibTeX | Tags: Animals, Biological, Diptera, Ecdysone, Ecdysterone, hoffmann, Larva, M3i, Metamorphosis, Muscles, Organ Culture Techniques

1977

Hoffmann Danièle, Brehelin M, Hoffmann Jules A

First results of the antibacterial defense reactions of Locusta migratoria larva and imago Journal Article

In: Ann Parasitol Hum Comp, vol. 52, no. 1, pp. 87–88, 1977, ISSN: 0003-4150.

BibTeX | Tags: Animals, Bacillus thuringiensis, bacteria, Cellular, Grasshoppers, Hematopoietic System, Hemocytes, Hemolymph, hoffmann, Immunity, Larva, M3i, Muramidase

1976

Feyereisen R, Lagueux Marie, Hoffmann Jules A

Dynamics of ecdysone metabolism after ingestion and injection in Locusta migratoria Journal Article

In: Gen. Comp. Endocrinol., vol. 29, no. 3, pp. 319–327, 1976, ISSN: 0016-6480.

BibTeX | Tags: Animals, Ecdysone, Grasshoppers, hoffmann, Hydroxylation, Injections, Intestines, Larva, M3i, Malpighian Tubules, Oral

1975

Feyereisen R, Lagueux Marie, Hoffmann Jules A

The hemolymphatic transport of molting hormone during the development of Locusta migratoria L Journal Article

In: C.R. Hebd. Seances Acad. Sci., Ser. D, Sci. Nat., vol. 280, no. 14, pp. 1709–1712, 1975.

Abstract | BibTeX | Tags: Age Factors, Animals, Carrier Proteins, Chromatography, Ecdysone, Ecdysterone, Gel, Grasshoppers, Hematopoietic System, hoffmann, Larva, M3i, Neurosecretory Systems, Protein Binding, Time Factors

Hoffmann Jules A, Koolman J, Beyler C

The role of the prothoracic glands in the production of ecdysone during the last larval instar of Locusta migratoria L Journal Article

In: C.R. Hebd. Seances Acad. Sci., Ser. D, Sci. Nat., vol. 280, no. 6, pp. 733–736, 1975.

Abstract | BibTeX | Tags: Animals, Cholesterol, Ecdysone, Grasshoppers, hoffmann, Larva, M3i

1974

Hoffmann Jules A, Weins M J

Active protein synthesis in the prothoracic glands and ecdysone titer in the permanent larvae of Locusta migratoria after selective irradiation of hematopoietic tissue Journal Article

In: Experientia, vol. 30, no. 7, pp. 821–822, 1974, ISSN: 0014-4754.

BibTeX | Tags: Animals, Ecdysone, Grasshoppers, Hematopoietic System, hoffmann, Larva, Leucine, M3i, Protein Biosynthesis, Radiation Effects, Tritium

Hoffmann Jules A, Koolman J, Karlson P, Joly P

Molting hormone titer and metabolic fate of injected ecdysone during the fifth larval instar and in adults of Locusta migratoria (Orthoptera) Journal Article

In: Gen. Comp. Endocrinol., vol. 22, no. 1, pp. 90–97, 1974, ISSN: 0016-6480.

BibTeX | Tags: Age Factors, Animals, Chromatography, Ecdysone, Feces, Grasshoppers, hoffmann, Hydroxylation, Invertebrate Hormones, Larva, M3i, Thin Layer, Time Factors, Tritium

1973

Koolman J, Hoffmann Jules A, Karlson P

Sulphage esters as inactivation products of ecdysone in Locusta migratoria Journal Article

In: Hoppe-Seyler's Z. Physiol. Chem., vol. 354, no. 9, pp. 1043–1048, 1973, ISSN: 0018-4888.

BibTeX | Tags: Animals, Biological, Cattle, Chromatography, Ecdysone, Electrophoresis, Esterases, Glucosidases, Glucuronidase, Grasshoppers, hoffmann, Hydrogen-Ion Concentration, Hydrolysis, Ion Exchange, Isotope Labeling, Kinetics, Larva, Liver, M3i, Metamorphosis, Paper, Plants, Saccharomyces cerevisiae, Snails, Sulfatases, Sulfur Radioisotopes, Sulfuric Acids, Swine, Thin Layer, Time Factors, Tritium

Zachary Daniel, Hoffmann Jules A

The haemocytes of Calliphora erythrocephala (Meig.) (Diptera) Journal Article

In: Z Zellforsch Mikrosk Anat, vol. 141, no. 1, pp. 55–73, 1973, ISSN: 0340-0336.

BibTeX | Tags: Animals, Cell Count, Cell Nucleus, Diptera, Electron, Endoplasmic Reticulum, Hemolymph, Hemostasis, hoffmann, Inclusion Bodies, Larva, Lipids, Lysosomes, M3i, Microscopy, mitochondria, Phase-Contrast, Pupa, Radiation Effects

Joly L, Weins M J, Hoffmann Jules A, Porte A

Development of the prothoracic glands of permanent larvae of Locusta migratoria obtained by selective irradiation of the hemocytopoietic tissue Journal Article

In: Z Zellforsch Mikrosk Anat, vol. 137, no. 3, pp. 387–397, 1973, ISSN: 0340-0336.

BibTeX | Tags: Age Factors, Animals, Biological, Ecdysone, Electron, Endocrine Glands, Golgi Apparatus, Grasshoppers, hoffmann, Larva, M3i, Metamorphosis, Microscopy, Radiation Effects, ribosomes