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2014

Imler Jean-Luc

Overview of Drosophila immunity: a historical perspective Journal Article

In: Developmental and Comparative Immunology, vol. 42, no. 1, pp. 3–15, 2014, ISSN: 1879-0089.

Abstract | Links | BibTeX | Tags: Allergy and Immunology, Animal, Animals, Antimicrobial Cationic Peptides, Antimicrobial peptides, history, Humans, IMD pathway, imler, Immunity, Innate, innate immunity, M3i, Models, Pattern recognition receptors, Signal Transduction, Toll-Like Receptors

Haller Samantha, Limmer Stefanie, Ferrandon Dominique

Assessing Pseudomonas virulence with a nonmammalian host: Drosophila melanogaster Journal Article

In: Methods Mol. Biol., vol. 1149, pp. 723–740, 2014, ISSN: 1940-6029.

Abstract | Links | BibTeX | Tags: Animal, Animals, Antimicrobial Cationic Peptides, Biological Assay, Colony Count, Disease Models, ferrandon, Hemolymph, Host-Pathogen Interactions, M3i, Mammals, Microbial, Pseudomonas aeruginosa, Pseudomonas Infections, Reverse Transcriptase Polymerase Chain Reaction, Virulence

2013

Baron Olga Lucia, van West Pieter, Industri Benoit, Ponchet Michel, Dubreuil Géraldine, Gourbal Benjamin, Reichhart Jean-Marc, Coustau Christine

Parental transfer of the antimicrobial protein LBP/BPI protects Biomphalaria glabrata eggs against oomycete infections Journal Article

In: PLoS Pathog., vol. 9, no. 12, pp. e1003792, 2013, ISSN: 1553-7374.

Abstract | Links | BibTeX | Tags: Acute-Phase Proteins, Animals, Antimicrobial Cationic Peptides, Biomphalaria, Blood Proteins, Carrier Proteins, Cell Membrane, Cell Membrane Permeability, Cloning, Escherichia coli, Female, Immunity, infection, M3i, Maternally-Acquired, Membrane Glycoproteins, Microbial Sensitivity Tests, Molecular, Oomycetes, Recombinant Proteins, reichhart, Zygote

2011

Nehme Nadine T, Quintin Jessica, Cho Ju Hyun, Lee Janice, Lafarge Marie-Céline, Kocks Christine, Ferrandon Dominique

Relative roles of the cellular and humoral responses in the Drosophila host defense against three gram-positive bacterial infections Journal Article

In: PLoS ONE, vol. 6, no. 3, pp. e14743, 2011, ISSN: 1932-6203.

Abstract | Links | BibTeX | Tags: Animals, Antimicrobial Cationic Peptides, Carrier Proteins, Cell Surface, Cellular, Enterococcus faecalis, ferrandon, Gram-Positive Bacteria, Gram-Positive Bacterial Infections, Host-Pathogen Interactions, Humoral, Immunity, Innate, M3i, Micrococcus luteus, Opsonin Proteins, Phagocytosis, Receptors, Signal Transduction, Solubility, Staphylococcus aureus

2006

Bischoff Vincent, Vignal Cécile, Duvic Bernard, Boneca Ivo G, Hoffmann Jules A, Royet Julien

Downregulation of the Drosophila immune response by peptidoglycan-recognition proteins SC1 and SC2 Journal Article

In: PLoS Pathog., vol. 2, no. 2, pp. e14, 2006, ISSN: 1553-7374.

Abstract | Links | BibTeX | Tags: Animals, Antimicrobial Cationic Peptides, bacteria, Carrier Proteins, Down-Regulation, hoffmann, Larva, M3i, RNA Interference, Signal Transduction

2005

Royet Julien, Reichhart Jean-Marc, Hoffmann Jules A

Sensing and signaling during infection in Drosophila Journal Article

In: Curr. Opin. Immunol., vol. 17, no. 1, pp. 11–17, 2005, ISSN: 0952-7915.

Abstract | Links | BibTeX | Tags: Animals, Antimicrobial Cationic Peptides, Bacterial Infections, Gene Expression Regulation, Genome, hoffmann, Immunity, Innate, M3i, reichhart, Signal Transduction

Imler Jean-Luc, Bulet Philippe

Antimicrobial peptides in Drosophila: structures, activities and gene regulation Journal Article

In: Chemical Immunology and Allergy, vol. 86, pp. 1–21, 2005, ISSN: 1660-2242.

Abstract | Links | BibTeX | Tags: Animals, Antimicrobial Cationic Peptides, Defensins, Gene Expression Regulation, Genes, Glycopeptides, imler, Immunity, Innate, Insect, Insect Proteins, M3i, Molecular Structure, Signal Transduction

2003

Thouzeau Cécile, Maho Yvon Le, Froget Guillaume, Sabatier Laurence, Bohec Céline Le, Hoffmann Jules A, Bulet Philippe

Spheniscins, avian beta-defensins in preserved stomach contents of the king penguin, Aptenodytes patagonicus Journal Article

In: J. Biol. Chem., vol. 278, no. 51, pp. 51053–51058, 2003, ISSN: 0021-9258.

Abstract | Links | BibTeX | Tags: Animals, Antimicrobial Cationic Peptides, bacteria, beta-Defensins, Birds, Feeding Behavior, Fungi, Gastrointestinal Contents, hoffmann, M3i, Male, Mass, Matrix-Assisted Laser Desorption-Ionization, Protein Isoforms, Sequence Alignment, Spectrometry

2002

Ligoxygakis Petros, Bulet Philippe, Reichhart Jean-Marc

Critical evaluation of the role of the Toll-like receptor 18-Wheeler in the host defense of Drosophila Journal Article

In: EMBO Rep., vol. 3, no. 7, pp. 666–673, 2002, ISSN: 1469-221X.

Abstract | Links | BibTeX | Tags: Animals, Anti-Bacterial Agents, Antimicrobial Cationic Peptides, Cell Adhesion Molecules, Fat Body, Gene Expression Regulation, Genes, Immunohistochemistry, Immunologic, Insect, Insect Proteins, Larva, M3i, Mass, Matrix-Assisted Laser Desorption-Ionization, Membrane Proteins, Receptors, reichhart, Reporter, Spectrometry, Transgenes

Tauszig-Delamasure Servane, Bilak Hana, Capovilla Maria, Hoffmann Jules A, Imler Jean-Luc

Drosophila MyD88 is required for the response to fungal and Gram-positive bacterial infections Journal Article

In: Nature Immunology, vol. 3, no. 1, pp. 91–97, 2002, ISSN: 1529-2908.

Abstract | Links | BibTeX | Tags: Adaptor Proteins, Amino Acid, Animals, Antigens, Antimicrobial Cationic Peptides, Cell Surface, Chromosome Mapping, Differentiation, Disease Susceptibility, Enterococcus faecalis, Epistasis, Escherichia coli, Female, Gene Expression Regulation, Genes, Genetic, Genetically Modified, Gram-Negative Bacteria, hoffmann, Hypocreales, imler, Immunologic, Insect, Insect Proteins, M3i, Membrane Glycoproteins, Micrococcus luteus, Myeloid Differentiation Factor 88, Protein Structure, Protein-Serine-Threonine Kinases, Receptors, Recombinant Fusion Proteins, Sequence Alignment, Sequence Homology, Signal Transducing, Tertiary, Toll-Like Receptors, Transfection

2001

Boulanger Nathalie, Ehret-Sabatier Laurence, Brun R, Zachary Daniel, Bulet Philippe, Imler Jean-Luc

Immune response of Drosophila melanogaster to infection with the flagellate parasite Crithidia spp Journal Article

In: Insect Biochemistry and Molecular Biology, vol. 31, no. 2, pp. 129–137, 2001, ISSN: 0965-1748.

Abstract | BibTeX | Tags: Animals, Anti-Bacterial Agents, Antimicrobial Cationic Peptides, Crithidia, Defensins, Gene Expression, Glycopeptides, Hemocytes, imler, Insect Proteins, M3i, Phagocytosis

1999

Levashina Elena A, Langley E, Green C, Gubb David, Ashburner M, Hoffmann Jules A, Reichhart Jean-Marc

Constitutive activation of toll-mediated antifungal defense in serpin-deficient Drosophila Journal Article

In: Science, vol. 285, no. 5435, pp. 1917–1919, 1999, ISSN: 0036-8075.

Abstract | BibTeX | Tags: Animals, Antifungal Agents, Antimicrobial Cationic Peptides, Body Patterning, Cell Surface, Escherichia coli, Genes, Hemolymph, hoffmann, Insect, Insect Proteins, M3i, Membrane Glycoproteins, Micrococcus luteus, Mutagenesis, Peptides, Receptors, Recombinant Fusion Proteins, reichhart, Serine Proteinase Inhibitors, Serpins, Signal Transduction, Toll-Like Receptors, Up-Regulation

1998

Levashina Elena A, Ohresser S, Lemaitre Bruno, Imler Jean-Luc

Two distinct pathways can control expression of the gene encoding the Drosophila antimicrobial peptide metchnikowin Journal Article

In: Journal of Molecular Biology, vol. 278, no. 3, pp. 515–527, 1998, ISSN: 0022-2836.

Abstract | Links | BibTeX | Tags: Animals, Anti-Infective Agents, Antimicrobial Cationic Peptides, Base Sequence, Cloning, Gene Expression Regulation, Genes, Genetic, Genetically Modified, Glycopeptides, imler, Insect, Insect Proteins, Larva, M3i, Molecular, Mutation, Peptides, Promoter Regions, Recombinant Fusion Proteins, Reporter, Restriction Mapping, Transcription

1996

Gross I, Georgel Philippe, Kappler Christine, Reichhart Jean-Marc, Hoffmann Jules A

Drosophila immunity: a comparative analysis of the Rel proteins dorsal and Dif in the induction of the genes encoding diptericin and cecropin Journal Article

In: Nucleic Acids Res., vol. 24, no. 7, pp. 1238–1245, 1996, ISSN: 0305-1048.

Abstract | BibTeX | Tags: Animals, Antimicrobial Cationic Peptides, Base Sequence, DNA Primers, DNA-Binding Proteins, Gene Expression Regulation, Genetic, hoffmann, Insect Hormones, Insect Proteins, M3i, NF-kappa B, Nuclear Proteins, Peptides, Phosphoproteins, reichhart, Transcription, Transcription Factors, Transcriptional Activation

Fehlbaum P, Bulet Philippe, Chernysh S, Briand J P, Roussel J P, Letellier L, Hetru Charles, Hoffmann Jules A

Structure-activity analysis of thanatin, a 21-residue inducible insect defense peptide with sequence homology to frog skin antimicrobial peptides Journal Article

In: Proc. Natl. Acad. Sci. U.S.A., vol. 93, no. 3, pp. 1221–1225, 1996, ISSN: 0027-8424.

Abstract | BibTeX | Tags: Amino Acid, Amphibian Proteins, Animals, Anti-Bacterial Agents, Anti-Infective Agents, Antimicrobial Cationic Peptides, Cyclic, Fungi, Gram-Negative Bacteria, Gram-Positive Bacteria, Hemiptera, hoffmann, M3i, Mass Spectrometry, Microbial Sensitivity Tests, Peptides, Ranidae, Sequence Homology, Skin, Structure-Activity Relationship

1995

Lemaitre Bruno, Kromer-Metzger E, Michaut Lydia, Nicolas E, Meister Marie, Georgel Philippe, Reichhart Jean-Marc, Hoffmann Jules A

A recessive mutation, immune deficiency (imd), defines two distinct control pathways in the Drosophila host defense Journal Article

In: Proc. Natl. Acad. Sci. U.S.A., vol. 92, no. 21, pp. 9465–9469, 1995, ISSN: 0027-8424.

Abstract | BibTeX | Tags: Animals, Anti-Bacterial Agents, Antimicrobial Cationic Peptides, Bacterial Infections, Base Sequence, Gene Expression Regulation, Genes, Glycopeptides, hoffmann, Insect, Insect Hormones, Insect Proteins, M3i, Male, Mutation, Mycoses, Nucleic Acid, Peptides, Protein Binding, Recessive, Regulatory Sequences, reichhart, Reporter, Survival Analysis

Levashina Elena A, Ohresser S, Bulet Philippe, Reichhart Jean-Marc, Hetru Charles, Hoffmann Jules A

Metchnikowin, a novel immune-inducible proline-rich peptide from Drosophila with antibacterial and antifungal properties Journal Article

In: Eur. J. Biochem., vol. 233, no. 2, pp. 694–700, 1995, ISSN: 0014-2956.

Abstract | BibTeX | Tags: Animals, Anti-Bacterial Agents, Antifungal Agents, Antimicrobial Cationic Peptides, bacteria, Base Sequence, Cells, Chromosome Mapping, Cloning, Cultured, Genetic, hoffmann, M3i, Molecular, Peptides, Proline, reichhart, Transcription

Lemaitre Bruno, Meister Marie, Govind S, Georgel Philippe, Steward R, Reichhart Jean-Marc, Hoffmann Jules A

Functional analysis and regulation of nuclear import of dorsal during the immune response in Drosophila Journal Article

In: EMBO J., vol. 14, no. 3, pp. 536–545, 1995, ISSN: 0261-4189.

Abstract | BibTeX | Tags: Animals, Anti-Bacterial Agents, Anti-Infective Agents, Antimicrobial Cationic Peptides, Biological Transport, Cell Nucleus, Cell Surface, DNA-Binding Proteins, Fat Body, Gene Expression Regulation, Genetic, hoffmann, Immunity, Immunohistochemistry, Insect Hormones, Insect Proteins, M3i, Melanins, Membrane Glycoproteins, Mutation, Neoplasms, Nuclear Proteins, Phosphoproteins, Receptors, reichhart, Signal Transduction, Toll-Like Receptors, Transcription, Transcription Factors

1994

Cociancich S, Dupont A, Hegy G, Lanot R, Holder F, Hetru Charles, Hoffmann Jules A, Bulet Philippe

Novel inducible antibacterial peptides from a hemipteran insect, the sap-sucking bug Pyrrhocoris apterus Journal Article

In: Biochem. J., vol. 300 ( Pt 2), pp. 567–575, 1994, ISSN: 0264-6021.

Abstract | BibTeX | Tags: Amino Acid, Animals, Anti-Bacterial Agents, Antimicrobial Cationic Peptides, Blood Proteins, Chromatography, Defensins, Gas Chromatography-Mass Spectrometry, Gel, Gram-Negative Bacteria, Gram-Positive Bacteria, Hemiptera, Hemolymph, hoffmann, Insect Proteins, M3i, Peptides, Sequence Homology

1992

Bulet Philippe, Cociancich S, Reuland M, Sauber F, Bischoff R, Hegy G, Dorsselaer Van A, Hetru Charles, Hoffmann Jules A

A novel insect defensin mediates the inducible antibacterial activity in larvae of the dragonfly Aeschna cyanea (Paleoptera, Odonata) Journal Article

In: Eur. J. Biochem., vol. 209, no. 3, pp. 977–984, 1992, ISSN: 0014-2956.

Abstract | BibTeX | Tags: Animals, Anti-Bacterial Agents, Antimicrobial Cationic Peptides, Blood Bactericidal Activity, Blood Proteins, Defensins, Hemolymph, hoffmann, Insect Proteins, insects, Larva, M3i, Mass Spectrometry, Peptides

1990

Hoffmann Jules A, Hoffmann Danièle

The inducible antibacterial peptides of dipteran insects Journal Article

In: Res. Immunol., vol. 141, no. 9, pp. 910–918, 1990, ISSN: 0923-2494.

BibTeX | Tags: Animals, Antimicrobial Cationic Peptides, Defensins, Diptera, Gene Expression Regulation, Genetic, hoffmann, Insect Hormones, Insect Proteins, M3i, Nucleic Acid, Proteins, Sequence Homology, Transcription