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2011

Gaillard Claire, Duval Monique, Dumortier Hélène, Bianco Alberto

Carbon nanotube-coupled cell adhesion peptides are non-immunogenic: a promising step toward new biomedical devices Journal Article

In: Journal of Peptide Science: An Official Publication of the European Peptide Society, vol. 17, no. 2, pp. 139–142, 2011, ISSN: 1099-1387.

Abstract | Links | BibTeX | Tags: carbon, Dumortier, Enzyme-Linked Immunosorbent Assay, I2CT, Nanotubes, Peptides, Team-Bianco, Team-Dumortier

2010

Noordegraaf Madelon, Flacher Vincent, Stoitzner Patrizia, Clausen Björn E

Functional redundancy of Langerhans cells and Langerin+ dermal dendritic cells in contact hypersensitivity Journal Article

In: The Journal of Investigative Dermatology, vol. 130, no. 12, pp. 2752–2759, 2010, ISSN: 1523-1747.

Abstract | Links | BibTeX | Tags: Animal, Animals, Antigen, Antigens, C-Type, CHS, contact, CONTACT HYPERSENSITIVITY, Dendritic Cells, DEPLETION, DERMAL DENDRITIC CELLS, Dermatitis, DERMIS, Diphtheria Toxin, Disease Models, Epidermis, function, Gene Knock-In Techniques, Genetics, Growth, HAPTEN, Haptens, Heparin-binding EGF-like Growth Factor, Hypersensitivity, Immunology, Inbred C57BL, INDUCTION, Intercellular Signaling Peptides and Proteins, LACKING, Langerhans Cells, LECTIN, Lectins, LYMPH, LYMPH NODE, Lymph Nodes, Mannose-Binding Lectins, metabolism, Mice, mouse, Mutant Strains, Organ Culture Techniques, pathology, Peptides, Poisons, Protein, Proteins, RESPONSES, signaling, Skin, Surface, Team-Mueller, Toxicity

2009

Geotti-Bianchini Piero, Crisma Marco, Peggion Cristina, Bianco Alberto, Formaggio Fernando

Synthesis and 3D-structure of conformationally controlled nucleo-peptides Journal Article

In: Advances in Experimental Medicine and Biology, vol. 611, pp. 37–38, 2009, ISSN: 0065-2598.

Links | BibTeX | Tags: I2CT, Models, Molecular, Nucleoproteins, Peptides, Protein Conformation, Team-Bianco

Gaillard Claire, Cellot Giada, Li Shouping, Toma Francesca Maria, Dumortier Hélène, Spalluto Giampiero, Cacciari Barbara, Prato Maurizio, Ballerini Laura, Bianco Alberto

Carbon Nanotubes Carrying Cell-Adhesion Peptides do not Interfere with Neuronal Functionality Journal Article

In: Advanced Materials, vol. 21, no. 28, pp. 2903–2908, 2009, ISSN: 1521-4095.

Abstract | Links | BibTeX | Tags: Carbon nanotubes, Cytotoxicity, I2CT, mammalian cells, Neurons, Peptides, Team-Bianco

2008

Geotti-Bianchini Piero, Beyrath Julien, Chaloin Olivier, Formaggio Fernando, Bianco Alberto

Design and synthesis of intrinsically cell-penetrating nucleopeptides Journal Article

In: Organic & Biomolecular Chemistry, vol. 6, no. 20, pp. 3661–3663, 2008, ISSN: 1477-0539.

Abstract | Links | BibTeX | Tags: Amino Acid Sequence, Cell Line, Cells, Drug Design, Humans, I2CT, Molecular Sequence Data, Peptides, Purines, Pyrimidines, Team-Bianco

Muller Sylviane, Monneaux Fanny, Schall Nicolas, Rashkov Rasho K, Oparanov Boycho A, Wiesel Philippe, Geiger Jean-Marie, Zimmer Robert

Spliceosomal peptide P140 for immunotherapy of systemic lupus erythematosus: results of an early phase II clinical trial Journal Article

In: Arthritis and Rheumatism, vol. 58, no. 12, pp. 3873–3883, 2008, ISSN: 0004-3591.

Abstract | Links | BibTeX | Tags: Adolescent, Adult, Aged, Antibodies, Antinuclear, C-Reactive Protein, DNA, Female, Humans, I2CT, Immunotherapy, Lupus Erythematosus, Male, Middle Aged, Monneaux, Peptide Fragments, Peptides, Severity of Illness Index, Spliceosomes, Systemic, Team-Dumortier, Treatment Outcome, Young Adult

2007

Monneaux Fanny, Muller Sylviane

Peptide-based therapy in lupus: promising data Journal Article

In: Advances in Experimental Medicine and Biology, vol. 601, pp. 105–112, 2007, ISSN: 0065-2598.

Abstract | Links | BibTeX | Tags: Adrenal Cortex Hormones, Animals, Autoantigens, Autoimmune Diseases, Cyclophosphamide, Epitopes, Humans, I2CT, Immune System, Immunosuppressive Agents, inflammation, Lupus Erythematosus, Monneaux, Peptides, Systemic, T-Lymphocytes, Team-Dumortier

2006

Campidelli Stéphane, Klumpp Cédric, Bianco Alberto, Guldi Dirk M, Prato Maurizio

Functionalization of CNT: synthesis and applications in photovoltaics and biology Journal Article

In: Journal of Physical Organic Chemistry, vol. 19, no. 8-9, pp. 531–539, 2006, ISSN: 1099-1395.

Abstract | Links | BibTeX | Tags: Carbon nanotubes, Cells, Drug delivery, electron transfer, Functionalization, I2CT, Peptides, photovoltaic, Team-Bianco, Toxicity, Vectors

2005

Fournel Sylvie, Wieckowski Sébastien, Sun Weimin, Trouche Nathalie, Dumortier Hélène, Bianco Alberto, Chaloin Olivier, Habib Mohammed, Peter Jean-Christophe, Schneider Pascal, Vray Bernard, Toes René E, Offringa Rienk, Melief Cornelis J M, Hoebeke Johan, Guichard Gilles

C3-symmetric peptide scaffolds are functional mimetics of trimeric CD40L Journal Article

In: Nature Chemical Biology, vol. 1, no. 7, pp. 377–382, 2005, ISSN: 1552-4450.

Abstract | Links | BibTeX | Tags: Animals, Apoptosis, Biological, CD40 Antigens, CD40 Ligand, Cell Line, Dumortier, Humans, I2CT, Inbred BALB C, Mice, Models, Molecular Mimicry, Molecular Structure, Peptides, Protein Conformation, Protein Structure, Quaternary, Structure-Activity Relationship, Team-Bianco, Team-Dumortier, Time Factors, tumor

Bianco Alberto, Kostarelos Kostas, Prato Maurizio

Applications of carbon nanotubes in drug delivery Journal Article

In: Current Opinion in Chemical Biology, vol. 9, no. 6, pp. 674–679, 2005, ISSN: 1367-5931.

Abstract | Links | BibTeX | Tags: Biological, carbon, Drug Delivery Systems, Electron, HeLa Cells, Humans, I2CT, Microscopy, Models, Nanotubes, Nucleic Acids, Peptides, scanning, Team-Bianco

Bianco Alberto

Efficient solid-phase synthesis of fullero-peptides using Merrifield strategy Journal Article

In: Chemical Communications (Cambridge, England), no. 25, pp. 3174–3176, 2005, ISSN: 1359-7345.

Abstract | Links | BibTeX | Tags: Chromatography, Fullerenes, High Pressure Liquid, I2CT, Mass Spectrometry, Peptides, Team-Bianco

Fournel Sylvie, Wieckowski Sébastien, Sun Weimin, Trouche Nathalie, Dumortier Hélène, Bianco Alberto, Chaloin Olivier, Habib Mohammed, Peter Jean-Christophe, Schneider Pascal, Vray Bernard, Toes René E, Offringa Rienk, Melief Cornelis J M, Hoebeke Johan, Guichard Gilles

C3-symmetric peptide scaffolds are functional mimetics of trimeric CD40L Journal Article

In: Nature Chemical Biology, vol. 1, no. 7, pp. 377–382, 2005, ISSN: 1552-4450.

Abstract | Links | BibTeX | Tags: Animals, Apoptosis, Biological, CD40 Antigens, CD40 Ligand, Cell Line, Humans, I2CT, Inbred BALB C, Mice, Models, Molecular Mimicry, Molecular Structure, Peptides, Protein Conformation, Protein Structure, Quaternary, Structure-Activity Relationship, Team-Bianco, Time Factors, tumor

2004

Monneaux Fanny, Parietti Véronique, Briand Jean-Paul, Muller Sylviane

Intramolecular Ŧ cell spreading in unprimed MRL/lpr mice: importance of the U1-70k protein sequence 131-151 Journal Article

In: Arthritis and Rheumatism, vol. 50, no. 10, pp. 3232–3238, 2004, ISSN: 0004-3591.

Abstract | Links | BibTeX | Tags: Animals, Cell Division, Female, I2CT, Immunization, Inbred BALB C, Inbred MRL lpr, Lupus Erythematosus, Lymphocytes, Mice, Monneaux, Peptides, Phosphorylation, Ribonucleoprotein, Systemic, Team-Dumortier, U1 Small Nuclear

Pantarotto Davide, Tagmatarchis Nikos, Bianco Alberto, Prato Maurizio

Synthesis and biological properties of fullerene-containing amino acids and peptides Journal Article

In: Mini Reviews in Medicinal Chemistry, vol. 4, no. 7, pp. 805–814, 2004, ISSN: 1389-5575.

Abstract | BibTeX | Tags: Amino Acids, Animals, Fullerenes, Humans, I2CT, Molecular Structure, Peptides, Solubility, Team-Bianco

Poschalko Alexander, Lancelot Nathalie, Marin Julien, Larras Virginie, Limal David, Elbayed Karim, Raya Jesus, Piotto Martial, Briand Jean-Paul, Guichard Gilles, Bianco Alberto

DEUSS: A Perdeuterated Poly(oxyethylene)-Based Resin for Improving HRMAS NMR Studies of Solid-Supported Molecules Journal Article

In: Chemistry – A European Journal, vol. 10, no. 18, pp. 4532–4537, 2004, ISSN: 0947-6539.

Abstract | Links | BibTeX | Tags: combinatorial chemistry, I2CT, NMR spectroscopy, oligoureas, Peptides, poly(oxyethylene), Resins, Team-Bianco

Monneaux Fanny, Muller Sylviane

Peptide-based immunotherapy of systemic lupus erythematosus Journal Article

In: Autoimmunity Reviews, vol. 3, no. 1, pp. 16–24, 2004, ISSN: 1568-9972.

Abstract | Links | BibTeX | Tags: Animals, Antibodies, Antinuclear, Epitopes, Humans, I2CT, Immunotherapy, Lupus Erythematosus, Mice, Monneaux, Peptides, Systemic, T-Lymphocytes, Team-Dumortier

Pantarotto Davide, Briand Jean-Paul, Prato Maurizio, Bianco Alberto

Translocation of bioactive peptides across cell membranes by carbon nanotubes Journal Article

In: Chemical Communications (Cambridge, England), no. 1, pp. 16–17, 2004, ISSN: 1359-7345.

Abstract | Links | BibTeX | Tags: 3T3 Cells, Animals, carbon, Cell Membrane, Confocal, Flow Cytometry, fluorescence, I2CT, Mice, Microscopy, Nanotubes, Particle Size, Peptides, Protein Transport, Team-Bianco

2003

Bianco Alberto, Pantarotto Davide, Hoebeke Johan, Briand Jean-Paul, Prato Maurizio

Solid-phase synthesis and characterization of a novel fullerene-peptide derived from histone H3 Journal Article

In: Organic & Biomolecular Chemistry, vol. 1, no. 23, pp. 4141–4143, 2003, ISSN: 1477-0520.

Abstract | Links | BibTeX | Tags: Chromatography, Epitopes, Fullerenes, Glutamic Acid, High Pressure Liquid, Histones, I2CT, Models, Molecular, Molecular Structure, Peptides, Protein Structure, Team-Bianco, Tertiary

Pantarotto Davide, Partidos Charalambos D, Hoebeke Johan, Brown Fred, Kramer Ed, Briand Jean-Paul, Muller Sylviane, Prato Maurizio, Bianco Alberto

Immunization with peptide-functionalized carbon nanotubes enhances virus-specific neutralizing antibody responses Journal Article

In: Chemistry & Biology, vol. 10, no. 10, pp. 961–966, 2003, ISSN: 1074-5521.

Links | BibTeX | Tags: Animals, Antibodies, Antigen-Antibody Reactions, carbon, Drug Delivery Systems, Epitopes, Foot-and-Mouth Disease Virus, I2CT, Immunization, Mice, Monoclonal, Nanotubes, Neutralization Tests, Peptides, Team-Bianco, Vaccines, Viral

Hetru Charles, Troxler Laurent, Hoffmann Jules A

Drosophila melanogaster antimicrobial defense Journal Article

In: J. Infect. Dis., vol. 187 Suppl 2, pp. S327–334, 2003, ISSN: 0022-1899.

Abstract | Links | BibTeX | Tags: Animal, Animals, Bacterial Infections, bioinformatic, hoffmann, Immunity, Innate, M3i, Mycoses, Parasitic Diseases, Peptides, Signal Transduction

Lancelot Nathalie, Elbayed Karim, Raya Jésus, Piotto Martial, Briand Jean-Paul, Formaggio Fernando, Toniolo Claudio, Bianco Alberto

Characterization of the 310-helix in model peptides by HRMAS NMR spectroscopy Journal Article

In: Chemistry (Weinheim an Der Bergstrasse, Germany), vol. 9, no. 6, pp. 1317–1323, 2003, ISSN: 0947-6539.

Abstract | Links | BibTeX | Tags: biomolecular, Fourier Transform Infrared, I2CT, Nuclear Magnetic Resonance, Peptides, Protein Conformation, spectroscopy, Team-Bianco

2002

Christophides George K, Zdobnov Evgeny, Barillas-Mury Carolina, Birney Ewan, Blandin Stephanie A, Blass Claudia, Brey Paul T, Collins Frank H, Danielli Alberto, Dimopoulos George, Hetru Charles, Hoa Ngo T, Hoffmann Jules A, Kanzok Stefan M, Letunic Ivica, Levashina Elena A, Loukeris Thanasis G, Lycett Gareth, Meister Stephan, Michel Kristin, Moita Luis F, Müller Hans-Michael, Osta Mike A, Paskewitz Susan M, Reichhart Jean-Marc, Rzhetsky Andrey, Troxler Laurent, Vernick Kenneth D, Vlachou Dina, Volz Jennifer, von Mering Christian, Xu Jiannong, Zheng Liangbiao, Bork Peer, Kafatos Fotis C

Immunity-related genes and gene families in Anopheles gambiae Journal Article

In: Science, vol. 298, no. 5591, pp. 159–165, 2002, ISSN: 1095-9203.

Abstract | Links | BibTeX | Tags: Alternative Splicing, Animals, Anopheles, Apoptosis, bacteria, bioinformatic, blandin, Catechol Oxidase, Computational Biology, Enzyme Precursors, Gene Expression Regulation, Genes, Genetic, Genome, hoffmann, Immunity, Innate, Insect, Insect Proteins, M3i, Multigene Family, Peptides, Phylogeny, Plasmodium, Protein Structure, reichhart, Selection, Serine Endopeptidases, Serpins, Signal Transduction, Tertiary

Raya Jésus, Bianco Alberto, Furrer Julien, Briand Jean-Paul, Piotto Martial, Elbayed Karim

Proton dipolar recoupling in resin-bound peptides under high-resolution magic angle spinning Journal Article

In: Journal of Magnetic Resonance (San Diego, Calif.: 1997), vol. 157, no. 1, pp. 43–51, 2002, ISSN: 1090-7807.

Abstract | Links | BibTeX | Tags: Amino Acid Sequence, biomolecular, Foot-and-Mouth Disease Virus, I2CT, Nuclear Magnetic Resonance, Peptides, Plant, Resins, Team-Bianco

2001

Bianco A, Ros T Da, Prato M, Toniolo C

Fullerene-based amino acids and peptides Journal Article

In: Journal of Peptide Science: An Official Publication of the European Peptide Society, vol. 7, no. 4, pp. 208–219, 2001, ISSN: 1075-2617.

Abstract | Links | BibTeX | Tags: Amino Acids, Animals, Antiviral Agents, carbon, Fullerenes, Humans, I2CT, Infections, Oxidative Stress, Peptides, Proline, Team-Bianco

Lamberty M, Zachary Daniel, Lanot R, Bordereau C, Robert A, Hoffmann Jules A, Bulet Philippe

Insect immunity. Constitutive expression of a cysteine-rich antifungal and a linear antibacterial peptide in a termite insect. Journal Article

In: J. Biol. Chem., vol. 276, no. 6, pp. 4085–4092, 2001, ISSN: 0021-9258.

Abstract | Links | BibTeX | Tags: Amino Acid, Animals, Anti-Bacterial Agents, Antifungal Agents, Base Sequence, Chromatography, Cysteine, DNA Primers, High Pressure Liquid, hoffmann, Immunohistochemistry, Isoptera, M3i, Peptides, Protein Conformation, Recombinant Proteins, Sequence Homology

2000

Casimir J R, Iterbeke K, Nest W Van Den, Trescol-Biémont M C, Dumortier H, Muller S, Gerlier D, Rabourdin-Combe C, Tourwé D, Paris J

Conformational restriction of the Tyr53 side-chain in the decapeptide HE Journal Article

In: The Journal of Peptide Research: Official Journal of the American Peptide Society, vol. 56, no. 6, pp. 398–408, 2000, ISSN: 1397-002X.

Abstract | Links | BibTeX | Tags: Amino Acid Sequence, Animals, Antigen, Antigen-Presenting Cells, B-Lymphocytes, Chemical, Chickens, Dumortier, I2CT, Major Histocompatibility Complex, Mice, Models, Molecular Sequence Data, Muramidase, Peptide Biosynthesis, Peptides, Phenylalanine, Protein Binding, Protein Conformation, Receptors, T-Cell, Team-Dumortier, Temperature, Tyrosine

Tauszig Servane, Jouanguy Emmanuelle, Hoffmann Jules A, Imler Jean-Luc

Toll-related receptors and the control of antimicrobial peptide expression in Drosophila Journal Article

In: Proceedings of the National Academy of Sciences of the United States of America, vol. 97, no. 19, pp. 10520–10525, 2000, ISSN: 0027-8424.

Abstract | Links | BibTeX | Tags: Amino Acid, Animals, Anti-Bacterial Agents, Blotting, Cell Line, Cell Surface, hoffmann, imler, M3i, Membrane Glycoproteins, Multigene Family, Northern, Peptides, Receptors, Reverse Transcriptase Polymerase Chain Reaction, Sequence Homology, Toll-Like Receptor 2, Toll-Like Receptor 4, Toll-Like Receptor 5, Toll-Like Receptors

1999

Levashina Elena A, Langley E, Green C, Gubb David, Ashburner M, Hoffmann Jules A, Reichhart Jean-Marc

Constitutive activation of toll-mediated antifungal defense in serpin-deficient Drosophila Journal Article

In: Science, vol. 285, no. 5435, pp. 1917–1919, 1999, ISSN: 0036-8075.

Abstract | BibTeX | Tags: Animals, Antifungal Agents, Antimicrobial Cationic Peptides, Body Patterning, Cell Surface, Escherichia coli, Genes, Hemolymph, hoffmann, Insect, Insect Proteins, M3i, Membrane Glycoproteins, Micrococcus luteus, Mutagenesis, Peptides, Receptors, Recombinant Fusion Proteins, reichhart, Serine Proteinase Inhibitors, Serpins, Signal Transduction, Toll-Like Receptors, Up-Regulation

Nisole S, Krust B, Callebaut C, Guichard G, Muller S, Briand J P, Hovanessian A G

The anti-HIV pseudopeptide HB-19 forms a complex with the cell-surface-expressed nucleolin independent of heparan sulfate proteoglycans Journal Article

In: The Journal of Biological Chemistry, vol. 274, no. 39, pp. 27875–27884, 1999, ISSN: 0021-9258.

Abstract | Links | BibTeX | Tags: Anti-HIV Agents, Binding Sites, CD4-Positive T-Lymphocytes, Cell Line, Cell Membrane, Confocal, Fibroblast Growth Factor 2, Flow Cytometry, Heparan Sulfate Proteoglycans, HIV-1, Humans, Microscopy, Oligopeptides, Peptides, Phospholipid Ethers, Phosphoproteins, Proteins, RNA-Binding Proteins

Dumortier H, Abbal M, Fort M, Briand J P, Cantagrel A, Muller S

MHC class II gene associations with autoantibodies to U1A and SmD1 proteins Journal Article

In: International Immunology, vol. 11, no. 2, pp. 249–257, 1999, ISSN: 0953-8178.

Abstract | Links | BibTeX | Tags: Alleles, Antibody Specificity, Autoantibodies, Autoantigens, Autoimmune Diseases, Blotting, Dumortier, Enzyme-Linked Immunosorbent Assay, Genes, HLA-DP Antigens, HLA-DP beta-Chains, HLA-DQ Antigens, HLA-DQ beta-Chains, HLA-DR Antigens, HLA-DRB1 Chains, Humans, I2CT, MHC Class II, Peptides, Rheumatic Diseases, Ribonucleoprotein, Ribonucleoproteins, RNA-Binding Proteins, Small Nuclear, snRNP Core Proteins, Team-Dumortier, U1 Small Nuclear, Western

1998

Uttenweiler-Joseph S, Moniatte M, Lagueux Marie, Dorsselaer Van A, Hoffmann Jules A, Bulet Philippe

Differential display of peptides induced during the immune response of Drosophila: a matrix-assisted laser desorption ionization time-of-flight mass spectrometry study Journal Article

In: Proc. Natl. Acad. Sci. U.S.A., vol. 95, no. 19, pp. 11342–11347, 1998, ISSN: 0027-8424.

Abstract | BibTeX | Tags: Animals, bacteria, Chromatography, Cloning, Hemolymph, High Pressure Liquid, hoffmann, Immunity, Insect Proteins, M3i, Mass, Matrix-Assisted Laser Desorption-Ionization, messenger, Molecular, Peptides, Protein Precursors, RNA, Sequence Analysis, Spectrometry, Time Factors

Bulet Philippe, Uttenweiler-Joseph S, Moniatte M, Dorsselaer Van A, Hoffmann Jules A

Differential display of peptides induced during the immune response of Drosophila: a matrix-assisted laser desorption ionization time-of-flight mass spectrometry study Journal Article

In: J. Protein Chem., vol. 17, no. 6, pp. 528–529, 1998, ISSN: 0277-8033.

BibTeX | Tags: Animals, Anti-Infective Agents, hoffmann, M3i, Mass, Matrix-Assisted Laser Desorption-Ionization, Peptide Biosynthesis, Peptides, Spectrometry

Levashina Elena A, Ohresser S, Lemaitre Bruno, Imler Jean-Luc

Two distinct pathways can control expression of the gene encoding the Drosophila antimicrobial peptide metchnikowin Journal Article

In: Journal of Molecular Biology, vol. 278, no. 3, pp. 515–527, 1998, ISSN: 0022-2836.

Abstract | Links | BibTeX | Tags: Animals, Anti-Infective Agents, Antimicrobial Cationic Peptides, Base Sequence, Cloning, Gene Expression Regulation, Genes, Genetic, Genetically Modified, Glycopeptides, imler, Insect, Insect Proteins, Larva, M3i, Molecular, Mutation, Peptides, Promoter Regions, Recombinant Fusion Proteins, Reporter, Restriction Mapping, Transcription

1997

Lemaitre Bruno, Reichhart Jean-Marc, Hoffmann Jules A

Drosophila host defense: differential induction of antimicrobial peptide genes after infection by various classes of microorganisms Journal Article

In: Proc. Natl. Acad. Sci. U.S.A., vol. 94, no. 26, pp. 14614–14619, 1997, ISSN: 0027-8424.

Abstract | BibTeX | Tags: Animals, Genes, hoffmann, Immunity, Insect, M3i, Peptides, reichhart

Meister Marie, Lemaitre Bruno, Hoffmann Jules A

Antimicrobial peptide defense in Drosophila Journal Article

In: Bioessays, vol. 19, no. 11, pp. 1019–1026, 1997, ISSN: 0265-9247.

Abstract | Links | BibTeX | Tags: Animals, Anti-Infective Agents, Gene Expression Regulation, Genetic, hoffmann, Insect Proteins, M3i, Models, Peptides, Promoter Regions, Signal Transduction

1996

Ehret-Sabatier L, Loew D, Goyffon M, Fehlbaum P, Hoffmann Jules A, van Dorsselaer A, Bulet Philippe

Characterization of novel cysteine-rich antimicrobial peptides from scorpion blood Journal Article

In: J. Biol. Chem., vol. 271, no. 47, pp. 29537–29544, 1996, ISSN: 0021-9258.

Abstract | BibTeX | Tags: Animals, Anti-Bacterial Agents, Chromatography, Cysteine, Electron, Hemolymph, Hemolysis, High Pressure Liquid, hoffmann, M3i, Mass Spectrometry, Microscopy, Peptides, Scorpions

Halimi H, Dumortier H, Briand J P, Muller S

Comparison of two different methods using overlapping synthetic peptides for localizing linear B cell epitopes in the U1 snRNP-C autoantigen Journal Article

In: Journal of Immunological Methods, vol. 199, no. 1, pp. 77–85, 1996, ISSN: 0022-1759.

Abstract | Links | BibTeX | Tags: Amino Acid Sequence, Autoantigens, B-Lymphocytes, Dumortier, Enzyme-Linked Immunosorbent Assay, Epitope Mapping, Humans, I2CT, Lupus Erythematosus, Molecular Sequence Data, Peptides, Ribonucleoprotein, Systemic, Team-Dumortier, U1 Small Nuclear

Gross I, Georgel Philippe, Kappler Christine, Reichhart Jean-Marc, Hoffmann Jules A

Drosophila immunity: a comparative analysis of the Rel proteins dorsal and Dif in the induction of the genes encoding diptericin and cecropin Journal Article

In: Nucleic Acids Res., vol. 24, no. 7, pp. 1238–1245, 1996, ISSN: 0305-1048.

Abstract | BibTeX | Tags: Animals, Antimicrobial Cationic Peptides, Base Sequence, DNA Primers, DNA-Binding Proteins, Gene Expression Regulation, Genetic, hoffmann, Insect Hormones, Insect Proteins, M3i, NF-kappa B, Nuclear Proteins, Peptides, Phosphoproteins, reichhart, Transcription, Transcription Factors, Transcriptional Activation

Hoffmann Jules A, Reichhart Jean-Marc, Hetru Charles

Innate immunity in higher insects Journal Article

In: Curr. Opin. Immunol., vol. 8, no. 1, pp. 8–13, 1996, ISSN: 0952-7915.

Abstract | BibTeX | Tags: Animals, Base Sequence, Cyclic, hoffmann, Immunity, Immunologic, Immunological, Innate, insects, M3i, Models, Peptide Hydrolases, Peptides, Receptors, reichhart

Fehlbaum P, Bulet Philippe, Chernysh S, Briand J P, Roussel J P, Letellier L, Hetru Charles, Hoffmann Jules A

Structure-activity analysis of thanatin, a 21-residue inducible insect defense peptide with sequence homology to frog skin antimicrobial peptides Journal Article

In: Proc. Natl. Acad. Sci. U.S.A., vol. 93, no. 3, pp. 1221–1225, 1996, ISSN: 0027-8424.

Abstract | BibTeX | Tags: Amino Acid, Amphibian Proteins, Animals, Anti-Bacterial Agents, Anti-Infective Agents, Antimicrobial Cationic Peptides, Cyclic, Fungi, Gram-Negative Bacteria, Gram-Positive Bacteria, Hemiptera, hoffmann, M3i, Mass Spectrometry, Microbial Sensitivity Tests, Peptides, Ranidae, Sequence Homology, Skin, Structure-Activity Relationship

1995

Lemaitre Bruno, Kromer-Metzger E, Michaut Lydia, Nicolas E, Meister Marie, Georgel Philippe, Reichhart Jean-Marc, Hoffmann Jules A

A recessive mutation, immune deficiency (imd), defines two distinct control pathways in the Drosophila host defense Journal Article

In: Proc. Natl. Acad. Sci. U.S.A., vol. 92, no. 21, pp. 9465–9469, 1995, ISSN: 0027-8424.

Abstract | BibTeX | Tags: Animals, Anti-Bacterial Agents, Antimicrobial Cationic Peptides, Bacterial Infections, Base Sequence, Gene Expression Regulation, Genes, Glycopeptides, hoffmann, Insect, Insect Hormones, Insect Proteins, M3i, Male, Mutation, Mycoses, Nucleic Acid, Peptides, Protein Binding, Recessive, Regulatory Sequences, reichhart, Reporter, Survival Analysis

Levashina Elena A, Ohresser S, Bulet Philippe, Reichhart Jean-Marc, Hetru Charles, Hoffmann Jules A

Metchnikowin, a novel immune-inducible proline-rich peptide from Drosophila with antibacterial and antifungal properties Journal Article

In: Eur. J. Biochem., vol. 233, no. 2, pp. 694–700, 1995, ISSN: 0014-2956.

Abstract | BibTeX | Tags: Animals, Anti-Bacterial Agents, Antifungal Agents, Antimicrobial Cationic Peptides, bacteria, Base Sequence, Cells, Chromosome Mapping, Cloning, Cultured, Genetic, hoffmann, M3i, Molecular, Peptides, Proline, reichhart, Transcription

Briand J P, Guichard G, Dumortier H, Muller S

Retro-inverso peptidomimetics as new immunological probes. Validation and application to the detection of antibodies in rheumatic diseases Journal Article

In: The Journal of Biological Chemistry, vol. 270, no. 35, pp. 20686–20691, 1995, ISSN: 0021-9258.

Abstract | Links | BibTeX | Tags: Amino Acid Sequence, Animals, Antibodies, Autoantibodies, Autoimmune Diseases, Dumortier, Enzyme-Linked Immunosorbent Assay, Humans, I2CT, Immunoassay, Lupus Erythematosus, Mice, Molecular Sequence Data, Monoclonal, Peptide Fragments, Peptides, Rheumatic Diseases, Stereoisomerism, Structure-Activity Relationship, Systemic, Team-Dumortier

Hoffmann Jules A

Innate immunity of insects Journal Article

In: Curr. Opin. Immunol., vol. 7, no. 1, pp. 4–10, 1995, ISSN: 0952-7915.

Abstract | BibTeX | Tags: Animals, Anti-Bacterial Agents, Blood Proteins, Cellular, Defensins, Gene Expression Regulation, hoffmann, Immunity, Innate, insects, M3i, Peptides

1994

Fehlbaum P, Bulet Philippe, Michaut L, Lagueux Marie, Broekaert W F, Hetru Charles, Hoffmann Jules A

Insect immunity. Septic injury of Drosophila induces the synthesis of a potent antifungal peptide with sequence homology to plant antifungal peptides Journal Article

In: J. Biol. Chem., vol. 269, no. 52, pp. 33159–33163, 1994, ISSN: 0021-9258.

Abstract | BibTeX | Tags: Amino Acid, Animals, Antifungal Agents, Base Sequence, Cloning, Complementary, DNA, hoffmann, Insect Proteins, M3i, Male, messenger, Microbial Sensitivity Tests, Molecular, Peptide Biosynthesis, Peptides, Plants, Protein Biosynthesis, Protein Precursors, Proteins, RNA, Sequence Homology

Cociancich S, Dupont A, Hegy G, Lanot R, Holder F, Hetru Charles, Hoffmann Jules A, Bulet Philippe

Novel inducible antibacterial peptides from a hemipteran insect, the sap-sucking bug Pyrrhocoris apterus Journal Article

In: Biochem. J., vol. 300 ( Pt 2), pp. 567–575, 1994, ISSN: 0264-6021.

Abstract | BibTeX | Tags: Amino Acid, Animals, Anti-Bacterial Agents, Antimicrobial Cationic Peptides, Blood Proteins, Chromatography, Defensins, Gas Chromatography-Mass Spectrometry, Gel, Gram-Negative Bacteria, Gram-Positive Bacteria, Hemiptera, Hemolymph, hoffmann, Insect Proteins, M3i, Peptides, Sequence Homology

1992

Bulet Philippe, Cociancich S, Reuland M, Sauber F, Bischoff R, Hegy G, Dorsselaer Van A, Hetru Charles, Hoffmann Jules A

A novel insect defensin mediates the inducible antibacterial activity in larvae of the dragonfly Aeschna cyanea (Paleoptera, Odonata) Journal Article

In: Eur. J. Biochem., vol. 209, no. 3, pp. 977–984, 1992, ISSN: 0014-2956.

Abstract | BibTeX | Tags: Animals, Anti-Bacterial Agents, Antimicrobial Cationic Peptides, Blood Bactericidal Activity, Blood Proteins, Defensins, Hemolymph, hoffmann, Insect Proteins, insects, Larva, M3i, Mass Spectrometry, Peptides

Hoffmann Jules A, Hetru Charles

Insect defensins: inducible antibacterial peptides Journal Article

In: Immunol. Today, vol. 13, no. 10, pp. 411–415, 1992, ISSN: 0167-5699.

Abstract | Links | BibTeX | Tags: Amino Acid, Animals, Bacterial Infections, Blood Bactericidal Activity, Blood Proteins, Defensins, hoffmann, insects, M3i, Peptides, Sequence Homology

1987

Debono M, Barnhart M, Carrell C B, Hoffmann Jules A, Occolowitz J L, Abbott B J, Fukuda D S, Hamill R L, Biemann K, Herlihy W C

A21978C, a complex of new acidic peptide antibiotics: isolation, chemistry, and mass spectral structure elucidation Journal Article

In: J. Antibiot., vol. 40, no. 6, pp. 761–777, 1987, ISSN: 0021-8820.

Abstract | BibTeX | Tags: Acylation, Amino Acids, Anti-Bacterial Agents, Chemical Phenomena, Chemistry, Chromatography, Cyclic, Fatty Acids, Gas Chromatography-Mass Spectrometry, High Pressure Liquid, hoffmann, Hydrolysis, M3i, Magnetic Resonance Spectroscopy, Mass Spectrometry, Molecular Conformation, Peptides, Spectrophotometry, Streptomyces