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2013

Fukuyama Hidehiro, Verdier Yann, Guan Yongsheng, Makino-Okamura Chieko, Shilova Victoria, Liu Xi, Maksoud Elie, Matsubayashi Jun, Haddad Iman, Spirohn Kerstin, Ono Kenichiro, Hetru Charles, Rossier Jean, Ideker Trey, Boutros Michael, Vinh Joëlle, Hoffmann Jules A

Landscape of protein-protein interactions in Drosophila immune deficiency signaling during bacterial challenge Journal Article

In: Proc. Natl. Acad. Sci. U.S.A., vol. 110, no. 26, pp. 10717–10722, 2013, ISSN: 1091-6490.

Abstract | Links | BibTeX | Tags: Amino Acid, Animals, Chromatin Assembly and Disassembly, Escherichia coli, functional proteomics, Genes, Genetically Modified, Histone Acetyltransferases, hoffmann, Host-Pathogen Interactions, Humans, IMD interactome, Insect, M3i, Models, Molecular, Protein Interaction Maps, Sequence Homology, Signal Transduction, small ubiquitin-like modifier

2011

Limmer Stefanie, Haller Samantha, Drenkard Eliana, Lee Janice, Yu Shen, Kocks Christine, Ausubel Frederick M, Ferrandon Dominique

Pseudomonas aeruginosa RhlR is required to neutralize the cellular immune response in a Drosophila melanogaster oral infection model Journal Article

In: Proc. Natl. Acad. Sci. U.S.A., vol. 108, no. 42, pp. 17378–17383, 2011, ISSN: 1091-6490.

Abstract | Links | BibTeX | Tags: Animal, Animals, Bacteremia, Bacterial Proteins, Cellular, Disease Models, ferrandon, Genes, Genetically Modified, Hemolymph, Host-Pathogen Interactions, Immunity, Insect, M3i, Mutation, Oral, Pseudomonas aeruginosa, Pseudomonas Infections, Quorum Sensing, Trans-Activators, Viral, Virulence

2007

Mandin P., Repoila F., Vergassola M., Geissmann T., Cossart P.

Identification of new noncoding RNAs in Listeria monocytogenes and prediction of mRNA targets Journal Article

In: Nucleic Acids Res, vol. 35, no. 3, pp. 962-74, 2007, (1362-4962 (Electronic) Journal Article Research Support, Non-U.S. Gov't).

Abstract | BibTeX | Tags: 5', Assay, Bacterial, Base, Biology, Computational, Data, DNA, Electrophoretic, Flanking, Genes, Genomics, Intergenic/chemistry, Listeria, Messenger/chemistry/*metabolism, Mobility, Molecular, monocytogenes/*genetics/metabolism, Region, RNA, ROMBY, Sequence, Shift, Untranslated/analysis/*genetics/metabolism

2006

Frolet Cécile, Thoma Martine, Blandin Stéphanie A, Hoffmann Jules A, Levashina Elena A

Boosting NF-kappaB-dependent basal immunity of Anopheles gambiae aborts development of Plasmodium berghei Journal Article

In: Immunity, vol. 25, no. 4, pp. 677–685, 2006, ISSN: 1074-7613.

Abstract | Links | BibTeX | Tags: Animals, Anopheles gambiae, blandin, Gene Expression, Gene Expression Regulation, Genes, hoffmann, Immunity, Insect, M3i, NF-kappa B, Plasmodium berghei, telomerase

Durand Stéphanie H, Flacher Vincent, Roméas Annick, Carrouel Florence, Colomb Evelyne, Vincent Claude, Magloire Henry, Couble Marie-Lise, Bleicher Françoise, Staquet Marie-Jeanne, Lebecque Serge, Farges Jean-Christophe

Lipoteichoic acid increases TLR and functional chemokine expression while reducing dentin formation in in vitro differentiated human odontoblasts Journal Article

In: Journal of Immunology (Baltimore, Md.: 1950), vol. 176, no. 5, pp. 2880–2887, 2006, ISSN: 0022-1767.

Abstract | Links | BibTeX | Tags: Activation, Analysis, bacteria, Biosynthesis, BLOOD, Blood Vessels, Cell Differentiation, Cells, Chemistry, chemokines, COLLAGEN, Cultured, CXCL10, cytology, Dendritic Cells, DENTAL PULP, Dentin, development, Down-Regulation, Expression, extracellular, EXTRACELLULAR MATRIX, Extracellular Matrix Proteins, function, Gene, Gene Expression, Genes, Genetics, Gram-Positive Bacteria, Human, Humans, IMMATURE, Immunology, IN VITRO, In vivo, Innate immune response, lipopolysaccharide, Lipopolysaccharides, metabolism, migration, Odontoblasts, Organ Culture Techniques, Pharmacology, physiology, PRODUCTION, Protein, Proteins, Receptor, recognition, synthesis, Team-Mueller, Teichoic Acids, TLR7, Toll-Like Receptor 2, Up-Regulation

2005

Kocks Christine, Cho Ju Hyun, Nehme Nadine, Ulvila Johanna, Pearson Alan M, Meister Marie, Strom Charles, Conto Stephanie L, Hetru Charles, Stuart Lynda M, Stehle Thilo, Hoffmann Jules A, Reichhart Jean-Marc, Ferrandon Dominique, Rämet Mika, Ezekowitz Alan R B

Eater, a transmembrane protein mediating phagocytosis of bacterial pathogens in Drosophila Journal Article

In: Cell, vol. 123, no. 2, pp. 335–346, 2005, ISSN: 0092-8674.

Abstract | Links | BibTeX | Tags: Amino Acid, Amino Acid Motifs, Animals, Bacterial Infections, Cell Surface, Embryo, Escherichia coli, ferrandon, Flow Cytometry, Frameshift Mutation, Genes, Histidine, hoffmann, In Situ Hybridization, Insect, Insect Proteins, M3i, Macrophages, Membrane Proteins, messenger, Nonmammalian, Open Reading Frames, Phagocytosis, Receptors, reichhart, RNA, RNA Interference, Sequence Homology, Serratia marcescens

Fauny Jean Daniel, Silber Joël, Zider Alain

Drosophila Lipid Storage Droplet 2 gene (Lsd-2) is expressed and controls lipid storage in wing imaginal discs Journal Article

In: Developmental Dynamics: An Official Publication of the American Association of Anatomists, vol. 232, no. 3, pp. 725–732, 2005, ISSN: 1058-8388.

Abstract | Links | BibTeX | Tags: Animals, Biological, Drosophila, Drosophila Proteins, Embryo, Fat Body, Genes, I2CT, Imagerie, Insect, Larva, Lipid Metabolism, Metamorphosis, Mutation, Nonmammalian, Nuclear Proteins, Phosphoproteins, Wing

Imler Jean-Luc, Bulet Philippe

Antimicrobial peptides in Drosophila: structures, activities and gene regulation Journal Article

In: Chemical Immunology and Allergy, vol. 86, pp. 1–21, 2005, ISSN: 1660-2242.

Abstract | Links | BibTeX | Tags: Animals, Antimicrobial Cationic Peptides, Defensins, Gene Expression Regulation, Genes, Glycopeptides, imler, Immunity, Innate, Insect, Insect Proteins, M3i, Molecular Structure, Signal Transduction

2004

Martineau Y., Bec C. Le, Monbrun L., Allo V., Chiu I. M., Danos O., Moine H., Prats H., Prats A. C.

Internal ribosome entry site structural motifs conserved among mammalian fibroblast growth factor 1 alternatively spliced mRNAs Journal Article

In: Mol Cell Biol, vol. 24, no. 17, pp. 7622-35, 2004, (0270-7306 Journal Article).

Abstract | BibTeX | Tags: (Genetics), *5', *Alternative, *Nucleic, *Promoter, 1/*genetics, Acid, Alignment, Animals, Base, Cell, Conformation, Data, EHRESMANN, Factor, Fibroblast, Gene, Genes, Genetic, Gov't, Growth, Human, Line, Messenger/chemistry/*genetics/metabolism, Mice, Molecular, Muscle, Mutagenesis, Non-U.S., Regions, Ribosomes/*metabolism, RNA, Sequence, Site-Directed, Skeletal/cytology/physiology, Splicing, Structural/genetics, Support, Techniques, Transfer, Untranslated, Vectors

Blandin Stéphanie A, Levashina Elena A

Mosquito immune responses against malaria parasites Journal Article

In: Curr. Opin. Immunol., vol. 16, no. 1, pp. 16–20, 2004, ISSN: 0952-7915.

Abstract | BibTeX | Tags: Animals, Anopheles, blandin, Gene Library, Genes, Hemocytes, Host-Parasite Interactions, Immunity, Innate, Insect, Insect Vectors, M3i, Malaria, Plasmodium

2003

Gobert Vanessa, Gottar Marie, Matskevich Alexey A, Rutschmann Sophie, Royet Julien, Belvin Marcia, Hoffmann Jules A, Ferrandon Dominique

Dual activation of the Drosophila toll pathway by two pattern recognition receptors Journal Article

In: Science, vol. 302, no. 5653, pp. 2126–2130, 2003, ISSN: 1095-9203.

Abstract | Links | BibTeX | Tags: Animals, Carrier Proteins, Cell Surface, DNA Transposable Elements, ferrandon, Gene Expression, Genes, Gram-Negative Bacteria, Gram-Positive Bacteria, Hemolymph, hoffmann, Hypocreales, Insect, Insect Proteins, M3i, Mutation, Phenotype, Receptors, Serine Endopeptidases, Toll-Like Receptors

2002

Christophides George K, Zdobnov Evgeny, Barillas-Mury Carolina, Birney Ewan, Blandin Stephanie A, Blass Claudia, Brey Paul T, Collins Frank H, Danielli Alberto, Dimopoulos George, Hetru Charles, Hoa Ngo T, Hoffmann Jules A, Kanzok Stefan M, Letunic Ivica, Levashina Elena A, Loukeris Thanasis G, Lycett Gareth, Meister Stephan, Michel Kristin, Moita Luis F, Müller Hans-Michael, Osta Mike A, Paskewitz Susan M, Reichhart Jean-Marc, Rzhetsky Andrey, Troxler Laurent, Vernick Kenneth D, Vlachou Dina, Volz Jennifer, von Mering Christian, Xu Jiannong, Zheng Liangbiao, Bork Peer, Kafatos Fotis C

Immunity-related genes and gene families in Anopheles gambiae Journal Article

In: Science, vol. 298, no. 5591, pp. 159–165, 2002, ISSN: 1095-9203.

Abstract | Links | BibTeX | Tags: Alternative Splicing, Animals, Anopheles, Apoptosis, bacteria, bioinformatic, blandin, Catechol Oxidase, Computational Biology, Enzyme Precursors, Gene Expression Regulation, Genes, Genetic, Genome, hoffmann, Immunity, Innate, Insect, Insect Proteins, M3i, Multigene Family, Peptides, Phylogeny, Plasmodium, Protein Structure, reichhart, Selection, Serine Endopeptidases, Serpins, Signal Transduction, Tertiary

Ligoxygakis Petros, Pelte Nadège, Hoffmann Jules A, Reichhart Jean-Marc

Activation of Drosophila Toll during fungal infection by a blood serine protease Journal Article

In: Science, vol. 297, no. 5578, pp. 114–116, 2002, ISSN: 1095-9203.

Abstract | Links | BibTeX | Tags: Animals, Cell Surface, Chromosome Mapping, Escherichia coli, Female, Gene Expression Regulation, Genes, Gram-Positive Cocci, Hemolymph, hoffmann, Hypocreales, Insect, Insect Proteins, M3i, Male, Mutation, Protein Sorting Signals, Protein Structure, Receptors, reichhart, Serine Endopeptidases, Tertiary, Toll-Like Receptors

Gottar Marie, Gobert Vanessa, Michel Tatiana, Belvin Marcia, Duyk Geoffrey, Hoffmann Jules A, Ferrandon Dominique, Royet Julien

The Drosophila immune response against Gram-negative bacteria is mediated by a peptidoglycan recognition protein Journal Article

In: Nature, vol. 416, pp. 640–644, 2002, ISBN: 0028-0836.

Abstract | Links | BibTeX | Tags: Animal, Anti-Infective Agents/metabolism, Carrier Proteins/biosynthesis/genetics/*immunology, Drosophila melanogaster/genetics/*immunology/*microbiology, Drosophila Proteins/genetics/metabolism, Epistasis, Female, ferrandon, Genes, Genetic, Genetic Predisposition to Disease, Gram-Negative Bacteria/*immunology/physiology, hoffmann, Human, Insect/genetics, M3i, Messenger/genetics/metabolism, Mutation, Non-U.S. Gov't, P.H.S., Phenotype, RNA, Signal Transduction, Support, Survival Rate, Transgenes/genetics, U.S. Gov't

Micillino J. C., Coulais C., Binet S., Bottin M. C., Keith G., Moulin D., Rihn B. H.

Lack of genotoxicity of bitumen fumes in transgenic mouse lung Journal Article

In: Toxicology, vol. 170, no. 1-2, pp. 11-20, 2002, (0300-483x Journal Article).

Abstract | BibTeX | Tags: Adducts/drug, Aerosols, Animals, C57BL, Chromatography, DNA, DNA/drug, effects, effects/metabolism, Gases/*toxicity, Genes, Hydrocarbons/*toxicity, Inbred, Lac, Layer, Lung/*drug, Mice, Mutagenicity, Mutagens/*toxicity, Mutation/drug, Operon/genetics, Reporter/genetics, Tests, Thin, transgenic

Ligoxygakis Petros, Bulet Philippe, Reichhart Jean-Marc

Critical evaluation of the role of the Toll-like receptor 18-Wheeler in the host defense of Drosophila Journal Article

In: EMBO Rep., vol. 3, no. 7, pp. 666–673, 2002, ISSN: 1469-221X.

Abstract | Links | BibTeX | Tags: Animals, Anti-Bacterial Agents, Antimicrobial Cationic Peptides, Cell Adhesion Molecules, Fat Body, Gene Expression Regulation, Genes, Immunohistochemistry, Immunologic, Insect, Insect Proteins, Larva, M3i, Mass, Matrix-Assisted Laser Desorption-Ionization, Membrane Proteins, Receptors, reichhart, Reporter, Spectrometry, Transgenes

Tauszig-Delamasure Servane, Bilak Hana, Capovilla Maria, Hoffmann Jules A, Imler Jean-Luc

Drosophila MyD88 is required for the response to fungal and Gram-positive bacterial infections Journal Article

In: Nature Immunology, vol. 3, no. 1, pp. 91–97, 2002, ISSN: 1529-2908.

Abstract | Links | BibTeX | Tags: Adaptor Proteins, Amino Acid, Animals, Antigens, Antimicrobial Cationic Peptides, Cell Surface, Chromosome Mapping, Differentiation, Disease Susceptibility, Enterococcus faecalis, Epistasis, Escherichia coli, Female, Gene Expression Regulation, Genes, Genetic, Genetically Modified, Gram-Negative Bacteria, hoffmann, Hypocreales, imler, Immunologic, Insect, Insect Proteins, M3i, Membrane Glycoproteins, Micrococcus luteus, Myeloid Differentiation Factor 88, Protein Structure, Protein-Serine-Threonine Kinases, Receptors, Recombinant Fusion Proteins, Sequence Alignment, Sequence Homology, Signal Transducing, Tertiary, Toll-Like Receptors, Transfection

2001

Michel T, Reichhart Jean-Marc, Hoffmann Jules A, Royet Julien

Drosophila Toll is activated by Gram-positive bacteria through a circulating peptidoglycan recognition protein Journal Article

In: Nature, vol. 414, no. 6865, pp. 756–759, 2001, ISSN: 0028-0836.

Abstract | Links | BibTeX | Tags: Amino Acid, Animals, Anti-Bacterial Agents, Anti-Infective Agents, Bacillus thuringiensis, Carrier Proteins, Cell Surface, Chromosome Mapping, Enterococcus faecalis, Fungi, Genes, Gram-Positive Bacteria, Hemolymph, hoffmann, Humans, Insect, Insect Proteins, M3i, Membrane Glycoproteins, Micrococcus luteus, Mutation, Receptors, reichhart, Sequence Homology, Toll-Like Receptors

Jung Alain C, Criqui M C, Rutschmann Sophie, Hoffmann Jules A, Ferrandon Dominique

A microfluorometer assay to measure the expression of beta-galactosidase and green fluorescent protein reporter genes in single Drosophila flies Journal Article

In: BioTechniques, vol. 30, no. 3, pp. 594–598, 600–601, 2001, ISSN: 0736-6205.

Abstract | BibTeX | Tags: Animals, beta-Galactosidase, Cytophotometry, ferrandon, Genes, Green Fluorescent Proteins, hoffmann, Luminescent Proteins, M3i, Reporter

2000

Imler Jean-Luc, Hoffmann Jules A

Signaling mechanisms in the antimicrobial host defense of Drosophila Journal Article

In: Current Opinion in Microbiology, vol. 3, no. 1, pp. 16–22, 2000, ISSN: 1369-5274.

Abstract | BibTeX | Tags: Animals, Anti-Infective Agents, Cell Surface, Gene Expression Regulation, Genes, hoffmann, imler, Insect, Insect Proteins, M3i, Membrane Glycoproteins, Receptors, Signal Transduction, Toll-Like Receptors

Tzou P, Ohresser S, Ferrandon Dominique, Capovilla Maria, Reichhart Jean-Marc, Lemaitre Bruno, Hoffmann Jules A, Imler Jean-Luc

Tissue-specific inducible expression of antimicrobial peptide genes in Drosophila surface epithelia Journal Article

In: Immunity, vol. 13, pp. 737–48., 2000, ISSN: 1074-7613.

Abstract | BibTeX | Tags: *Genes, Animal, Anti-Infective Agents/*immunology/metabolism, Drosophila/genetics/*immunology, ferrandon, Gene Expression Regulation/*immunology, Genes, Glycoside Hydrolases/immunology, hoffmann, Human, imler, Insect, Insect Proteins/genetics/immunology, M3i, Non-U.S. Gov't, Organ Specificity, P.H.S., reichhart, Reporter, Support, Transfection, U.S. Gov't

Imler Jean-Luc, Tauszig Servane, Jouanguy Emmanuelle, Forestier C, Hoffmann Jules A

LPS-induced immune response in Drosophila Journal Article

In: Journal of Endotoxin Research, vol. 6, no. 6, pp. 459–462, 2000, ISSN: 0968-0519.

Abstract | BibTeX | Tags: Animals, Biological, Cell Line, Cell Surface, Defensins, Genes, Genetic, hoffmann, imler, Insect, Insect Proteins, Lipopolysaccharides, M3i, Membrane Glycoproteins, Models, Mutation, Promoter Regions, Receptors, Signal Transduction, Toll-Like Receptors

Meister Marie, Hetru Charles, Hoffmann Jules A

The antimicrobial host defense of Drosophila Journal Article

In: Curr. Top. Microbiol. Immunol., vol. 248, pp. 17–36, 2000, ISSN: 0070-217X.

BibTeX | Tags: Animals, Anti-Infective Agents, Fat Body, Genes, hoffmann, Insect, Insect Proteins, M3i

1999

Otten L, Salomone J Y, Helfer A, Schmidt J, Hammann P, Ruffray P De

Sequence and functional analysis of the left-hand part of the Ŧ-region from the nopaline-type Ti plasmid, pTiC58. Journal Article

In: Plant molecular biology, vol. 41, no. 6, pp. 765–776, 1999, ISSN: 0167-4412 0167-4412, (Place: Netherlands).

Abstract | Links | BibTeX | Tags: Agrobacterium tumefaciens/*genetics/pathogenicity, Bacterial/chemistry/*genetics, Bacterial/genetics, Chromosome Mapping, DNA, Gene Deletion, Genes, Genetic Complementation Test, Lycopersicon esculentum/genetics/microbiology, Medicinal/genetics/microbiology, Molecular Sequence Data, Mutation, Phylogeny, Plant Tumors/genetics/microbiology, Plants, Plasmids/chemistry/*genetics, PPSE, Sequence Analysis, Species Specificity, Tobacco/genetics/microbiology, Toxic, Virulence/genetics

Levashina Elena A, Langley E, Green C, Gubb David, Ashburner M, Hoffmann Jules A, Reichhart Jean-Marc

Constitutive activation of toll-mediated antifungal defense in serpin-deficient Drosophila Journal Article

In: Science, vol. 285, no. 5435, pp. 1917–1919, 1999, ISSN: 0036-8075.

Abstract | BibTeX | Tags: Animals, Antifungal Agents, Antimicrobial Cationic Peptides, Body Patterning, Cell Surface, Escherichia coli, Genes, Hemolymph, hoffmann, Insect, Insect Proteins, M3i, Membrane Glycoproteins, Micrococcus luteus, Mutagenesis, Peptides, Receptors, Recombinant Fusion Proteins, reichhart, Serine Proteinase Inhibitors, Serpins, Signal Transduction, Toll-Like Receptors, Up-Regulation

Manfruelli P, Reichhart Jean-Marc, Steward R, Hoffmann Jules A, Lemaitre Bruno

A mosaic analysis in Drosophila fat body cells of the control of antimicrobial peptide genes by the Rel proteins Dorsal and DIF Journal Article

In: EMBO J., vol. 18, no. 12, pp. 3380–3391, 1999, ISSN: 0261-4189.

Abstract | Links | BibTeX | Tags: Animals, Anti-Infective Agents, Cell Surface, Clone Cells, DNA-Binding Proteins, Fat Body, Female, Gene Expression Regulation, Genes, hoffmann, Insect, Insect Proteins, Larva, M3i, Male, Membrane Glycoproteins, Mosaicism, Mutation, Nuclear Proteins, Phosphoproteins, Receptors, reichhart, Reporter, Signal Transduction, Toll-Like Receptors, Transcription Factors

Dumortier H, Abbal M, Fort M, Briand J P, Cantagrel A, Muller S

MHC class II gene associations with autoantibodies to U1A and SmD1 proteins Journal Article

In: International Immunology, vol. 11, no. 2, pp. 249–257, 1999, ISSN: 0953-8178.

Abstract | Links | BibTeX | Tags: Alleles, Antibody Specificity, Autoantibodies, Autoantigens, Autoimmune Diseases, Blotting, Dumortier, Enzyme-Linked Immunosorbent Assay, Genes, HLA-DP Antigens, HLA-DP beta-Chains, HLA-DQ Antigens, HLA-DQ beta-Chains, HLA-DR Antigens, HLA-DRB1 Chains, Humans, I2CT, MHC Class II, Peptides, Rheumatic Diseases, Ribonucleoprotein, Ribonucleoproteins, RNA-Binding Proteins, Small Nuclear, snRNP Core Proteins, Team-Dumortier, U1 Small Nuclear, Western

1998

Hoet R M, Raats J M, de Wildt R, Dumortier H, Muller S, van den Hoogen F, van Venrooij W J

Human monoclonal autoantibody fragments from combinatorial antibody libraries directed to the U1snRNP associated U1C protein; epitope mapping, immunolocalization and V-gene usage Journal Article

In: Molecular Immunology, vol. 35, no. 16, pp. 1045–1055, 1998, ISSN: 0161-5890.

Abstract | Links | BibTeX | Tags: Amino Acid Sequence, Antibodies, Autoantibodies, Cross Reactions, Dumortier, Epitope Mapping, Genes, HeLa Cells, Humans, I2CT, Immunoglobulin, Immunoglobulin Fragments, Immunoglobulin Variable Region, Immunohistochemistry, Lupus Erythematosus, Monoclonal, Ribonucleoprotein, Ribonucleoproteins, Small Nuclear, Systemic, Team-Dumortier, U1 Small Nuclear

Ferrandon Dominique, Jung Alain C, Criqui M, Lemaitre Bruno, Uttenweiler-Joseph S, Michaut Lydia, Reichhart Jean-Marc, Hoffmann Jules A

A drosomycin-GFP reporter transgene reveals a local immune response in Drosophila that is not dependent on the Toll pathway Journal Article

In: EMBO J., vol. 17, no. 5, pp. 1217–1227, 1998, ISSN: 0261-4189.

Abstract | Links | BibTeX | Tags: Animals, bacteria, Cell Surface, Developmental, Digestive System, Epithelium, Fat Body, Female, ferrandon, Fungal, Gene Expression Regulation, Genes, Green Fluorescent Proteins, hoffmann, Insect Proteins, Larva, Luminescent Proteins, M3i, Male, Membrane Glycoproteins, Organ Specificity, Receptors, reichhart, Reporter, Respiratory System, Spores, Toll-Like Receptors, Trachea, Transgenes

Levashina Elena A, Ohresser S, Lemaitre Bruno, Imler Jean-Luc

Two distinct pathways can control expression of the gene encoding the Drosophila antimicrobial peptide metchnikowin Journal Article

In: Journal of Molecular Biology, vol. 278, no. 3, pp. 515–527, 1998, ISSN: 0022-2836.

Abstract | Links | BibTeX | Tags: Animals, Anti-Infective Agents, Antimicrobial Cationic Peptides, Base Sequence, Cloning, Gene Expression Regulation, Genes, Genetic, Genetically Modified, Glycopeptides, imler, Insect, Insect Proteins, Larva, M3i, Molecular, Mutation, Peptides, Promoter Regions, Recombinant Fusion Proteins, Reporter, Restriction Mapping, Transcription

1997

Lemaitre Bruno, Reichhart Jean-Marc, Hoffmann Jules A

Drosophila host defense: differential induction of antimicrobial peptide genes after infection by various classes of microorganisms Journal Article

In: Proc. Natl. Acad. Sci. U.S.A., vol. 94, no. 26, pp. 14614–14619, 1997, ISSN: 0027-8424.

Abstract | BibTeX | Tags: Animals, Genes, hoffmann, Immunity, Insect, M3i, Peptides, reichhart

Dimarcq Jean-Luc, Imler Jean-Luc, Lanot R, Ezekowitz Alan R B, Hoffmann Jules A, Janeway C A, Lagueux Marie

Treatment of l(2)mbn Drosophila tumorous blood cells with the steroid hormone ecdysone amplifies the inducibility of antimicrobial peptide gene expression Journal Article

In: Insect Biochemistry and Molecular Biology, vol. 27, no. 10, pp. 877–886, 1997, ISSN: 0965-1748.

Abstract | BibTeX | Tags: Animals, Bacterial Infections, Cellular, Ecdysone, Gene Expression, Genes, Hemocytes, Hemolymph, hoffmann, imler, Immunity, Insect, M3i, Macrophages, Peptide Biosynthesis, Phagocytosis

1996

Richman A M, Bulet Philippe, Hetru Charles, Barillas-Mury Carolina, Hoffmann Jules A, Kafalos Fotis C

Inducible immune factors of the vector mosquito Anopheles gambiae: biochemical purification of a defensin antibacterial peptide and molecular cloning of preprodefensin cDNA Journal Article

In: Insect Mol. Biol., vol. 5, no. 3, pp. 203–210, 1996, ISSN: 0962-1075.

Abstract | BibTeX | Tags: Amino Acid, Animals, Anopheles, Base Sequence, Blood Bactericidal Activity, Blood Proteins, Cloning, Complementary, Defensins, DNA, Escherichia coli, Female, Gene Expression, Genes, hoffmann, Insect, Insect Vectors, Larva, M3i, Micrococcus luteus, Molecular, Sequence Homology

Lemaitre Bruno, Nicolas E, Michaut Lydia, Reichhart Jean-Marc, Hoffmann Jules A

The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults Journal Article

In: Cell, vol. 86, no. 6, pp. 973–983, 1996, ISSN: 0092-8674.

Abstract | BibTeX | Tags: Animals, Antifungal Agents, Cell Surface, DNA-Binding Proteins, Fungi, Gene Expression, Genes, hoffmann, Insect, Insect Hormones, Insect Proteins, M3i, Membrane Glycoproteins, MHC Class II, Mutation, Mycoses, NF-kappa B, Phosphoproteins, Proteins, Receptors, reichhart, Signal Transduction, Toll-Like Receptors

1995

Lemaitre Bruno, Kromer-Metzger E, Michaut Lydia, Nicolas E, Meister Marie, Georgel Philippe, Reichhart Jean-Marc, Hoffmann Jules A

A recessive mutation, immune deficiency (imd), defines two distinct control pathways in the Drosophila host defense Journal Article

In: Proc. Natl. Acad. Sci. U.S.A., vol. 92, no. 21, pp. 9465–9469, 1995, ISSN: 0027-8424.

Abstract | BibTeX | Tags: Animals, Anti-Bacterial Agents, Antimicrobial Cationic Peptides, Bacterial Infections, Base Sequence, Gene Expression Regulation, Genes, Glycopeptides, hoffmann,