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2019

Bordoni Valentina, Reina Giacomo, Orecchioni Marco, Furesi Giulia, Thiele Stefanie, Gardin Chiara, Zavan Barbara, Cuniberti Gianaurelio, Bianco Alberto, Rauner Martina, Delogu Lucia G

Stimulation of bone formation by monocyte-activator functionalized graphene oxide in vivo Journal Article

In: Nanoscale, vol. 11, no. 41, pp. 19408–19421, 2019, ISSN: 2040-3372.

Abstract | Links | BibTeX | Tags: Animals, Biocompatible Materials, Bone Morphogenetic Protein 2, Calcium Phosphates, Cell Differentiation, Cell Survival, Coculture Techniques, Graphite, Humans, I2CT, Inbred C57BL, Male, Mesenchymal Stem Cells, Mice, Monocytes, Oncostatin M, Osteoblasts, Osteogenesis, Signal Transduction, Team-Bianco, Tibia, Wnt Proteins

Schaeffer Evelyne, Sánchez-Fernández Elena M, Gonçalves-Pereira Rita, Flacher Vincent, Lamon Delphine, Duval Monique, Fauny Jean-Daniel, Fernández José M García, Mueller Christopher G, Mellet Carmen Ortiz

sp2-Iminosugar glycolipids as inhibitors of lipopolysaccharide-mediated human dendritic cell activation in vitro and of acute inflammation in mice in vivo Journal Article

In: European Journal of Medicinal Chemistry, vol. 169, pp. 111–120, 2019, ISSN: 1768-3254.

Abstract | Links | BibTeX | Tags: Activation, Acute Disease, Animals, antagonists & inhibitors, CD14, Cells, chemical synthesis, Chemistry, CO-RECEPTOR, Cultured, Dendritic cell, Dendritic Cells, Dose-Response Relationship, Drug, drug effects, drug therapy, Glycolipid, Glycolipids, Human, Humans, Iminosugar, immunopathology, IN VITRO, In vivo, Inbred C57BL, inflammation, Interleukin-6, lipopolysaccharide, Lipopolysaccharides, LPS, Male, Maturation, metabolism, Mice, MICROGLIA, Molecular Structure, mouse, pathology, Pharmacology, PRODUCTION, Receptor, signaling, Structure-Activity Relationship, Sulfone, Sulfoxide, Tail, target, Team-Mueller

2018

Sawaf Matthieu, Fauny Jean-Daniel, Felten Renaud, Sagez Flora, Gottenberg Jacques-Eric, Dumortier Hélène, Monneaux Fanny

Defective BTLA functionality is rescued by restoring lipid metabolism in lupus CD4+ Ŧ cells Journal Article

In: JCI insight, vol. 3, no. 13, 2018, ISSN: 2379-3708.

Abstract | Links | BibTeX | Tags: 80 and over, Adolescent, Adult, Aged, Autoimmune Diseases, Autoimmunity, CD4-Positive T-Lymphocytes, Cell Proliferation, CTLA-4 Antigen, Dumortier, Female, France, Humans, I2CT, Imagerie, Immunologic, Immunology, Lipid Metabolism, lupus, Lupus Erythematosus, Lymphocyte Activation, Male, Middle Aged, Monneaux, Programmed Cell Death 1 Receptor, Receptors, Signal Transduction, Systemic, Team-Dumortier, Young Adult

2015

Jacquemin Clément, Schmitt Nathalie, Contin-Bordes Cécile, Liu Yang, Narayanan Priya, Seneschal Julien, Maurouard Typhanie, Dougall David, Davizon Emily Spence, Dumortier Hélène, Douchet Isabelle, Raffray Loïc, Richez Christophe, Lazaro Estibaliz, Duffau Pierre, Truchetet Marie-Elise, Khoryati Liliane, Mercié Patrick, Couzi Lionel, Merville Pierre, Schaeverbeke Thierry, Viallard Jean-François, Pellegrin Jean-Luc, Moreau Jean-François, Muller Sylviane, Zurawski Sandy, Coffman Robert L, Pascual Virginia, Ueno Hideki, Blanco Patrick

OX40 Ligand Contributes to Human Lupus Pathogenesis by Promoting Ŧ Follicular Helper Response Journal Article

In: Immunity, vol. 42, no. 6, pp. 1159–1170, 2015, ISSN: 1097-4180.

Abstract | Links | BibTeX | Tags: Adolescent, Adult, Aged, Antigen Presentation, B-Lymphocytes, Cell Differentiation, Cells, Cultured, Cytokines, Disease Progression, Dumortier, Female, Helper-Inducer, Humans, I2CT, Immunologic Memory, Inducible T-Cell Co-Stimulator Protein, Lupus Erythematosus, Lymphocyte Activation, Male, Middle Aged, Molecular Targeted Therapy, Myeloid Cells, OX40, OX40 Ligand, Receptors, RNA, Signal Transduction, Systemic, T-Lymphocytes, Team-Dumortier, Toll-Like Receptor 7, Young Adult

2014

Bonnay François, Nguyen Xuan-Hung, Cohen-Berros Eva, Troxler Laurent, Batsche Eric, Camonis Jacques, Takeuchi Osamu, Reichhart Jean-Marc, Matt Nicolas

Akirin specifies NF-κB selectivity of Drosophila innate immune response via chromatin remodeling Journal Article

In: EMBO J., vol. 33, no. 20, pp. 2349–2362, 2014, ISSN: 1460-2075.

Abstract | Links | BibTeX | Tags: Animals, bioinformatic, Cell Cycle Proteins, Chromatin Assembly and Disassembly, chromatin remodeling, DNA-Binding Proteins, Female, Genetic, Immunity, Innate, Innate immune response, M3i, Male, matt, Mutation, NF-kappa B, NF‐κB, Promoter Regions, proteomics, reichhart, Trans-Activators, Transcription Factors, Transcriptional Activation, Two-Hybrid System Techniques

Tartey Sarang, Matsushita Kazufumi, Vandenbon Alexis, Ori Daisuke, Imamura Tomoko, Mino Takashi, Standley Daron M, Hoffmann Jules A, Reichhart Jean-Marc, Akira Shizuo, Takeuchi Osamu

Akirin2 is critical for inducing inflammatory genes by bridging IκB-ζ and the SWI/SNF complex Journal Article

In: EMBO J., vol. 33, no. 20, pp. 2332–2348, 2014, ISSN: 1460-2075.

Abstract | Links | BibTeX | Tags: Adaptor Proteins, Animals, Cell Nucleus, Chromatin Assembly and Disassembly, chromatin remodeling, Chromosomal Proteins, cytokine, Cytokines, Female, Gene Expression Regulation, gene regulation, Genetic, hoffmann, Humans, Immunity, Innate, innate immunity, Knockout, Listeria monocytogenes, M3i, Macrophages, Male, Mice, Multiprotein Complexes, Non-Histone, Nuclear Proteins, Promoter Regions, Protein Binding, reichhart, Repressor Proteins, Sequence Deletion, Signal Transducing, Transcriptional Activation

Amcheslavsky Alla, Song Wei, Li Qi, Nie Yingchao, Bragatto Ivan, Ferrandon Dominique, Perrimon Norbert, Ip Tony Y

Enteroendocrine cells support intestinal stem-cell-mediated homeostasis in Drosophila Journal Article

In: Cell Rep, vol. 9, no. 1, pp. 32–39, 2014, ISSN: 2211-1247.

Abstract | Links | BibTeX | Tags: Animals, Cell Differentiation, Enterocytes, Enteroendocrine Cells, Female, ferrandon, Homeostasis, Intestines, M3i, Male, Stem Cells, Tachykinins

2013

Coz Carole Le, Joublin Aurélie, Pasquali Jean-Louis, Korganow Anne-Sophie, Dumortier Hélène, Monneaux Fanny

Circulating TFH subset distribution is strongly affected in lupus patients with an active disease Journal Article

In: PloS One, vol. 8, no. 9, pp. e75319, 2013, ISSN: 1932-6203.

Abstract | Links | BibTeX | Tags: Adult, Aged, B-Lymphocytes, Case-Control Studies, CD4 Lymphocyte Count, CD5 Antigens, CXCR5, Cytokines, Dumortier, Female, Flow Cytometry, Helper-Inducer, Humans, I2CT, Immunoglobulin E, Immunologic Memory, Immunophenotyping, Interleukin-21, Lupus Erythematosus, Male, Middle Aged, Monneaux, Phenotype, Receptors, Systemic, T-Lymphocytes, Team-Dumortier, Th2 Cells, Young Adult

2010

Parietti Véronique, Chifflot Hélène, Sibilia Jean, Muller Sylviane, Monneaux Fanny

Rituximab treatment overcomes reduction of regulatory iNKT cells in patients with rheumatoid arthritis Journal Article

In: Clinical Immunology (Orlando, Fla.), vol. 134, no. 3, pp. 331–339, 2010, ISSN: 1521-7035.

Abstract | Links | BibTeX | Tags: Adult, Age Factors, Aged, Antibodies, Antirheumatic Agents, arthritis, Female, Flow Cytometry, Humans, I2CT, Longitudinal Studies, Male, Middle Aged, Monneaux, Monoclonal, Murine-Derived, Natural Killer T-Cells, Nonparametric, rheumatoid, Rituximab, Sex Factors, Statistics, Team-Dumortier, Young Adult

2009

Chamouard Patrick, Monneaux Fanny, Richert Zoe, Voegeli Anne-Claire, Lavaux Thomas, Gaub Marie Pierre, Baumann René, Oudet Pierre, Muller Sylviane

Diminution of Circulating CD4+CD25 high Ŧ cells in naïve Crohn's disease Journal Article

In: Digestive Diseases and Sciences, vol. 54, no. 10, pp. 2084–2093, 2009, ISSN: 1573-2568.

Abstract | Links | BibTeX | Tags: Adult, Aged, Blood Cell Count, CD4 Antigens, Colitis, Crohn Disease, Female, Flow Cytometry, Humans, I2CT, Interleukin-2 Receptor alpha Subunit, Lymphocyte Subsets, Male, Middle Aged, Monneaux, Regulatory, T-Lymphocytes, Team-Dumortier, Ulcerative

Bosisio M R, Maisonneuve C, Gregoire S, Kettaneh A, Mueller C G, Bridal S L

Ultrasound biomicroscopy: a powerful tool probing murine lymph node size in vivo Journal Article

In: Ultrasound Med.Biol., vol. 35, no. 1879-291X (Electronic), pp. 1209–1216, 2009.

Abstract | BibTeX | Tags: Acoustic, Animals, Axilla, cancer, Cell Count, Female, Graft Rejection, Hyperplasia, immunodeficiency, In vivo, Inbred C57BL, inflammation, LYMPH, LYMPH NODE, Lymph Nodes, Male, methods, Mice, Microscopy, murine, Observer Variation, pathology, SKIN GRAFT, Skin Transplantation, Team-Mueller, transgenic, TRANSGENIC MICE, ultrasonography

Schett G, Dumortier H, Hoefler E, Muller S, Steiner G

B cell epitopes of the heterogeneous nuclear ribonucleoprotein A2: identification of a new specific antibody marker for active lupus disease Journal Article

In: Annals of the Rheumatic Diseases, vol. 68, no. 5, pp. 729–735, 2009, ISSN: 1468-2060.

Abstract | Links | BibTeX | Tags: Autoantibodies, B-Lymphocyte, Biomarkers, Dumortier, Enzyme-Linked Immunosorbent Assay, Epitopes, Female, Follow-Up Studies, Heterogeneous-Nuclear Ribonucleoprotein Group A-B, Humans, I2CT, Lupus Erythematosus, Male, Rheumatic Diseases, Severity of Illness Index, Systemic, Team-Dumortier

2008

Muller Sylviane, Monneaux Fanny, Schall Nicolas, Rashkov Rasho K, Oparanov Boycho A, Wiesel Philippe, Geiger Jean-Marie, Zimmer Robert

Spliceosomal peptide P140 for immunotherapy of systemic lupus erythematosus: results of an early phase II clinical trial Journal Article

In: Arthritis and Rheumatism, vol. 58, no. 12, pp. 3873–3883, 2008, ISSN: 0004-3591.

Abstract | Links | BibTeX | Tags: Adolescent, Adult, Aged, Antibodies, Antinuclear, C-Reactive Protein, DNA, Female, Humans, I2CT, Immunotherapy, Lupus Erythematosus, Male, Middle Aged, Monneaux, Peptide Fragments, Peptides, Severity of Illness Index, Spliceosomes, Systemic, Team-Dumortier, Treatment Outcome, Young Adult

2007

Winter F., Edaye S., Huttenhofer A., Brunel C.

Anopheles gambiae miRNAs as actors of defence reaction against Plasmodium invasion Journal Article

In: Nucleic Acids Res, vol. 35, no. 20, pp. 6953-62, 2007, (1362-4962 (Electronic) 0305-1048 (Linking) Journal Article Research Support, Non-U.S. Gov't).

Abstract | BibTeX | Tags: *Gene, Animals, Anopheles, BRUNEL, Digestive, Expression, Female, gambiae/*genetics/*immunology/parasitology, Gene, III/genetics, Library, Male, MicroRNAs/*immunology, Plasmodium/*immunology, Profiling, Ribonuclease, silencing, System/immunology/metabolism/parasitology

2005

Dostert Catherine, Jouanguy Emmanuelle, Irving Phil, Troxler Laurent, Galiana-Arnoux Delphine, Hetru Charles, Hoffmann Jules A, Imler Jean-Luc

The Jak-STAT signaling pathway is required but not sufficient for the antiviral response of drosophila Journal Article

In: Nature Immunology, vol. 6, no. 9, pp. 946–953, 2005, ISSN: 1529-2908.

Abstract | Links | BibTeX | Tags: Animals, bioinformatic, DNA-Binding Proteins, Genetic, Genetically Modified, hoffmann, imler, Insect Viruses, Janus Kinase 1, M3i, Male, Oligonucleotide Array Sequence Analysis, Promoter Regions, Protein-Tyrosine Kinases, Signal Transduction, STAT1 Transcription Factor, Trans-Activators

2004

van Mierlo Geertje J D, Boonman Zita F H M, Dumortier Hélène M H, den Boer Annemieke Th, Fransen Marieke F, Nouta Jan, van der Voort Ellen I H, Offringa Rienk, Toes René E M, Melief Cornelis J M

Activation of dendritic cells that cross-present tumor-derived antigen licenses CD8+ CTL to cause tumor eradication Journal Article

In: Journal of Immunology (Baltimore, Md.: 1950), vol. 173, no. 11, pp. 6753–6759, 2004, ISSN: 0022-1767.

Abstract | Links | BibTeX | Tags: Adenovirus E1A Proteins, Animals, Antibodies, Antigen-Presenting Cells, Antigens, CD11c Antigen, CD40 Antigens, Cross-Priming, Cultured, Cytotoxic, Cytotoxicity, Dendritic Cells, Dumortier, Epitopes, Experimental, I2CT, Immunologic, Inbred C57BL, Injections, Intralesional, Intravenous, Knockout, Male, Mice, Monoclonal, Neoplasms, T-Lymphocyte, T-Lymphocytes, Team-Dumortier, transgenic, tumor, Tumor Cells, Viral

de la Pena-Lefebvre P. Garcia, Chanseaud Y., Tamby M. C., Reinbolt J., Batteux F., Allanore Y., Kahan A., Meyer O., Benveniste O., Boyer O., Guillevin L., Boissier M. C., Mouthon L.

IgG reactivity with a 100-kDa tissue and endothelial cell antigen identified as topoisomerase 1 distinguishes between limited and diffuse systemic sclerosis patients Journal Article

In: Clin Immunol, vol. 111, no. 3, pp. 241-51, 2004, (1521-6616 Journal Article).

Abstract | BibTeX | Tags: Aged, Assay, Autoantibodies/*analysis, Blotting, Cells/*immunology, Centromere/immunology, DNA, EHRESMANN, Electrophoresis, Endothelial, Enzyme-Linked, Female, G/analysis, Gel, Gov't, Human, I/*immunology, Immunoglobulin, Immunosorbent, M/analysis, Male, Middle, Non-U.S., Polyacrylamide, Scleroderma, Support, Systemic/*immunology, Topoisomerases, Type, Western

Mohr S., Bottin M. C., Lannes B., Neuville A., Bellocq J. P., Keith G., Rihn B. H.

Microdissection, mRNA amplification and microarray: a study of pleural mesothelial and malignant mesothelioma cells Journal Article

In: Biochimie, vol. 86, no. 1, pp. 13-9, 2004, (0300-9084 Journal Article).

Abstract | BibTeX | Tags: Analysis, Array, Chain, Epithelium/*metabolism, Expression, Female, Gene, Genetic, Human, KEITH, Lasers, Male, Markers, Mesothelioma/*genetics/metabolism, messenger, Microdissection, Neoplasms/*genetics/metabolism, Neoplastic/*genetics, Oligonucleotide, Pleura/*cytology/*metabolism, Pleural, Polymerase, Profiling, Reaction, Regulation, Reverse, RNA, Sequence, Transcriptase

Zukiel R., Nowak S., Barciszewska A. M., Gawronska I., Keith G., Barciszewska M. Z.

A simple epigenetic method for the diagnosis and classification of brain tumors Journal Article

In: Mol Cancer Res, vol. 2, no. 3, pp. 196-202, 2004, (1541-7786 Journal Article).

Abstract | BibTeX | Tags: *DNA, *Epigenesis, 5-Methylcytosine/*analysis, Adult, Aged, and, Brain, Chromatography, DNA, Female, Genetic, Gov't, Human, KEITH, Layer, Male, Methylation, Middle, Neoplasm/*chemistry/*metabolism, Neoplasms/*classification/*diagnosis/genetics/pathology, Non-U.S., Oxidative, oxygen, Reactive, Sensitivity, Species/metabolism, Specificity, Stress, Support, Thin

2003

Thouzeau Cécile, Maho Yvon Le, Froget Guillaume, Sabatier Laurence, Bohec Céline Le, Hoffmann Jules A, Bulet Philippe

Spheniscins, avian beta-defensins in preserved stomach contents of the king penguin, Aptenodytes patagonicus Journal Article

In: J. Biol. Chem., vol. 278, no. 51, pp. 51053–51058, 2003, ISSN: 0021-9258.

Abstract | Links | BibTeX | Tags: Animals, Antimicrobial Cationic Peptides, bacteria, beta-Defensins, Birds, Feeding Behavior, Fungi, Gastrointestinal Contents, hoffmann, M3i, Male, Mass, Matrix-Assisted Laser Desorption-Ionization, Protein Isoforms, Sequence Alignment, Spectrometry

Luna C, Hoa N T, Zhang J, Kanzok S M, Brown S E, Imler Jean-Luc, Knudson D L, Zheng L

Characterization of three Toll-like genes from mosquito Aedes aegypti Journal Article

In: Insect Molecular Biology, vol. 12, no. 1, pp. 67–74, 2003, ISSN: 0962-1075.

Abstract | BibTeX | Tags: Aedes, Animals, Base Sequence, Cell Surface, Chimera, Cloning, Developmental, Female, Gene Expression Regulation, Genetic, imler, Insect Proteins, M3i, Male, messenger, Models, Molecular, Mutagenesis, Promoter Regions, Receptors, Reverse Transcriptase Polymerase Chain Reaction, RNA, Sequence Alignment, Signal Transduction, Site-Directed, Transfection

Kambris Zakaria, Bilak Hana, D'Alessandro Rosalba, Belvin Marcia, Imler Jean-Luc, Capovilla Maria

DmMyD88 controls dorsoventral patterning of the Drosophila embryo Journal Article

In: EMBO reports, vol. 4, no. 1, pp. 64–69, 2003, ISSN: 1469-221X.

Abstract | Links | BibTeX | Tags: Adaptor Proteins, Alleles, Animals, Antigens, Base Sequence, Cell Surface, Complementary, Developmental, Differentiation, DNA, DNA Transposable Elements, Egg Proteins, Embryo, Exons, Female, Gene Expression Regulation, Genetically Modified, Genotype, imler, Immunity, Immunologic, Innate, Insertional, M3i, Male, messenger, Morphogenesis, Mutagenesis, Myeloid Differentiation Factor 88, Nonmammalian, Oocytes, Protein Biosynthesis, Protein Structure, Receptors, Reverse Transcriptase Polymerase Chain Reaction, RNA, Signal Transducing, Tertiary, Toll-Like Receptors, Zygote

2002

Ligoxygakis Petros, Pelte Nadège, Hoffmann Jules A, Reichhart Jean-Marc

Activation of Drosophila Toll during fungal infection by a blood serine protease Journal Article

In: Science, vol. 297, no. 5578, pp. 114–116, 2002, ISSN: 1095-9203.

Abstract | Links | BibTeX | Tags: Animals, Cell Surface, Chromosome Mapping, Escherichia coli, Female, Gene Expression Regulation, Genes, Gram-Positive Cocci, Hemolymph, hoffmann, Hypocreales, Insect, Insect Proteins, M3i, Male, Mutation, Protein Sorting Signals, Protein Structure, Receptors, reichhart, Serine Endopeptidases, Tertiary, Toll-Like Receptors

2001

Irving Phil, Troxler Laurent, Heuer Timothy S, Belvin Marcia, Kopczynski Casey, Reichhart Jean-Marc, Hoffmann Jules A, Hetru Charles

A genome-wide analysis of immune responses in Drosophila Journal Article

In: Proc. Natl. Acad. Sci. U.S.A., vol. 98, no. 26, pp. 15119–15124, 2001, ISSN: 0027-8424.

Abstract | Links | BibTeX | Tags: Animals, bioinformatic, Gene Expression Regulation, Genome, Gram-Negative Bacteria, hoffmann, M3i, Male, Oligonucleotide Array Sequence Analysis, reichhart, Signal Transduction

Georgel Philippe, Naitza S, Kappler Christine, Ferrandon Dominique, Zachary Daniel, Swimmer C, Kopczynski C, Duyk G, Reichhart Jean-Marc, Hoffmann Jules A

Drosophila immune deficiency (IMD) is a death domain protein that activates antibacterial defense and can promote apoptosis Journal Article

In: Dev. Cell, vol. 1, no. 4, pp. 503–514, 2001, ISSN: 1534-5807.

Abstract | BibTeX | Tags: Animals, Anti-Infective Agents, Apoptosis, Bacterial Infections, Caspases, Chromosome Mapping, Cysteine Proteinase Inhibitors, DNA Damage, Female, ferrandon, Gene Expression, hoffmann, I-kappa B Kinase, Immunocompromised Host, In Situ Nick-End Labeling, Insect Proteins, M3i, Male, Mutation, Phenotype, Protein Structure, Protein-Serine-Threonine Kinases, reichhart, Tertiary

2000

Dumortier H, Monneaux F, Jahn-Schmid B, Briand J P, Skriner K, Cohen P L, Smolen J S, Steiner G, Muller S

B and Ŧ cell responses to the spliceosomal heterogeneous nuclear ribonucleoproteins A2 and B1 in normal and lupus mice Journal Article

In: Journal of Immunology (Baltimore, Md.: 1950), vol. 165, no. 4, pp. 2297–2305, 2000, ISSN: 0022-1767.

Abstract | Links | BibTeX | Tags: Amino Acid Sequence, Animals, Autoantibodies, B-Lymphocytes, Dumortier, Epitope Mapping, Female, Heterogeneous Nuclear, Heterogeneous-Nuclear Ribonucleoprotein Group A-B, Heterogeneous-Nuclear Ribonucleoproteins, Humans, I2CT, Immunoglobulin G, Inbred BALB C, Inbred C57BL, Inbred CBA, Inbred MRL lpr, Injections, Lupus Nephritis, Lymphocyte Activation, Male, Mice, Molecular Sequence Data, Monneaux, Peptide Fragments, Recombinant Proteins, Ribonucleoproteins, RNA, Spliceosomes, Subcutaneous, T-Lymphocytes, Team-Dumortier, transgenic

Obrecht-Pflumio S., Dirheimer G.

In vitro DNA and dGMP adducts formation caused by ochratoxin A Journal Article

In: Chem Biol Interact, vol. 127, no. 1, pp. 29-44, 2000, (0009-2797 Journal Article).

Abstract | BibTeX | Tags: Acid/metabolism, Adducts/*metabolism, Agents/pharmacology, Animals, Arachidonic, Carcinogens/pharmacology, Chelating, Chromatography, Deferoxamine/pharmacology, Deoxyguanine, DNA, Female, Kidney/ultrastructure, Liver/metabolism, Male, Mice, Microsomes, Microsomes/metabolism, Mycotoxins/pharmacology, NADP/metabolism, Nucleotides/*metabolism, Nucleotides/metabolism, Ochratoxins/*pharmacology, Peroxidase/metabolism, Rabbits, Spectrophotometry

Rihn B., Coulais C., Kauffer E., Bottin M. C., Martin P., Yvon F., Vigneron J. C., Binet S., Monhoven N., Steiblen G., Keith G.

Inhaled crocidolite mutagenicity in lung DNA Journal Article

In: Environ Health Perspect, vol. 108, no. 4, pp. 341-6, 2000, (0091-6765 Journal Article).

Abstract | BibTeX | Tags: &, Adducts/*genetics, Air, Alveolar/physiology, Animals, Asbestos, Crocidolite/administration, Damage/*genetics, DNA, dosage/*adverse, effects, effects/pathology, Exposure, Gov't, Inhalation, Lung/*drug, Macrophages, Male, Mice, Mutagenicity, Non-U.S., Pollutants/*adverse, Support, Tests, transgenic

1999

Manfruelli P, Reichhart Jean-Marc, Steward R, Hoffmann Jules A, Lemaitre Bruno

A mosaic analysis in Drosophila fat body cells of the control of antimicrobial peptide genes by the Rel proteins Dorsal and DIF Journal Article

In: EMBO J., vol. 18, no. 12, pp. 3380–3391, 1999, ISSN: 0261-4189.

Abstract | Links | BibTeX | Tags: Animals, Anti-Infective Agents, Cell Surface, Clone Cells, DNA-Binding Proteins, Fat Body, Female, Gene Expression Regulation, Genes, hoffmann, Insect, Insect Proteins, Larva, M3i, Male, Membrane Glycoproteins, Mosaicism, Mutation, Nuclear Proteins, Phosphoproteins, Receptors, reichhart, Reporter, Signal Transduction, Toll-Like Receptors, Transcription Factors

1998

Ferrandon Dominique, Jung Alain C, Criqui M, Lemaitre Bruno, Uttenweiler-Joseph S, Michaut Lydia, Reichhart Jean-Marc, Hoffmann Jules A

A drosomycin-GFP reporter transgene reveals a local immune response in Drosophila that is not dependent on the Toll pathway Journal Article

In: EMBO J., vol. 17, no. 5, pp. 1217–1227, 1998, ISSN: 0261-4189.

Abstract | Links | BibTeX | Tags: Animals, bacteria, Cell Surface, Developmental, Digestive System, Epithelium, Fat Body, Female, ferrandon, Fungal, Gene Expression Regulation, Genes, Green Fluorescent Proteins, hoffmann, Insect Proteins, Larva, Luminescent Proteins, M3i, Male, Membrane Glycoproteins, Organ Specificity, Receptors, reichhart, Reporter, Respiratory System, Spores, Toll-Like Receptors, Trachea, Transgenes

1995

Lemaitre Bruno, Kromer-Metzger E, Michaut Lydia, Nicolas E, Meister Marie, Georgel Philippe, Reichhart Jean-Marc, Hoffmann Jules A

A recessive mutation, immune deficiency (imd), defines two distinct control pathways in the Drosophila host defense Journal Article

In: Proc. Natl. Acad. Sci. U.S.A., vol. 92, no. 21, pp. 9465–9469, 1995, ISSN: 0027-8424.

Abstract | BibTeX | Tags: Animals, Anti-Bacterial Agents, Antimicrobial Cationic Peptides, Bacterial Infections, Base Sequence, Gene Expression Regulation, Genes, Glycopeptides, hoffmann, Insect, Insect Hormones, Insect Proteins, M3i, Male, Mutation, Mycoses, Nucleic Acid, Peptides, Protein Binding, Recessive, Regulatory Sequences, reichhart, Reporter, Survival Analysis

1994

Meister Marie, Braun A, Kappler Christine, Reichhart Jean-Marc, Hoffmann Jules A

Insect immunity. A transgenic analysis in Drosophila defines several functional domains in the diptericin promoter Journal Article

In: EMBO J., vol. 13, no. 24, pp. 5958–5966, 1994, ISSN: 0261-4189.

Abstract | BibTeX | Tags: Animals, Anti-Infective Agents, Base Sequence, beta-Galactosidase, DNA Mutational Analysis, Female, Gene Expression Regulation, Genetic, Genetically Modified, Germ Cells, hoffmann, Insect Hormones, Insect Proteins, M3i, Male, Models, Nucleic Acid, Promoter Regions, Recombinant Fusion Proteins, reichhart, Repetitive Sequences, Transformation

Fehlbaum P, Bulet Philippe, Michaut L, Lagueux Marie, Broekaert W F, Hetru Charles, Hoffmann Jules A

Insect immunity. Septic injury of Drosophila induces the synthesis of a potent antifungal peptide with sequence homology to plant antifungal peptides Journal Article

In: J. Biol. Chem., vol. 269, no. 52, pp. 33159–33163, 1994, ISSN: 0021-9258.

Abstract | BibTeX | Tags: Amino Acid, Animals, Antifungal Agents, Base Sequence, Cloning, Complementary, DNA, hoffmann, Insect Proteins, M3i, Male, messenger, Microbial Sensitivity Tests, Molecular, Peptide Biosynthesis, Peptides, Plants, Protein Biosynthesis, Protein Precursors, Proteins, RNA, Sequence Homology

1977

Lagueux Marie, Hirn M, Hoffmann Jules A

Ecdysone during ovarian development in Locusta migratoria Journal Article

In: J. Insect Physiol., vol. 23, no. 1, pp. 109–119, 1977, ISSN: 0022-1910.

BibTeX | Tags: Animals, Ecdysone, Female, Grasshoppers, hoffmann, M3i, Male, Oogenesis, Ovary

1970

Hoffmann Jules A

Endocrine regulation of production and differentiation of hemocytes in an orthopteran insect: Locusta migratoria migratoroides Journal Article

In: Gen. Comp. Endocrinol., vol. 15, no. 2, pp. 198–219, 1970, ISSN: 0016-6480.

BibTeX | Tags: Animals, Biological, Blood Cells, Electrocoagulation, Female, Hemolymph, hoffmann, insects, M3i, Male, Metamorphosis, Microscopy, Neurosecretory Systems, Phase-Contrast