Focus on ribosome traps in hox genes

This week eLife publishes a work of the team “Evolution of translation initiation systems in eukaryotes on hox genes involved in development in vertebrates and the discovery of sequences acting as ‘ribosome traps’ in their mRNAs and ensuring the regulation of their expression. Full details in the news of the CNRS Institute of Biological Sciences.

Contact: Franck Martin

Reference: Translation inhibitory elements from Hoxa3 and Hoxa11 mRNAs use uORFs for translation inhibition. Alghoul F, Laure S, Eriani G, Martin F. Elife. 2021 Jun 2;10:e66369. doi: 10.7554/eLife.66369